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The map label for this gene is argD [H]

Identifier: 116328124

GI number: 116328124

Start: 1655821

End: 1657041

Strand: Reverse

Name: argD [H]

Synonym: LBL_1422

Alternate gene names: 116328124

Gene position: 1657041-1655821 (Counterclockwise)

Preceding gene: 116328125

Following gene: 116328123

Centisome position: 45.84

GC content: 42.83

Gene sequence:

>1221_bases
ATGAACGACACAGACATCCACAAAGAACTTTTCCAACATACTAAGGAATTAGCGGATCATTATCTACTCAATACGTATTC
AAGATACGACGTAGCGTTTCGTTACGGAGTCAACGAACTTCTATTCGATTTTGATAATAAGCAGTATATTGATTTTCACT
GTGGAGTTGCAGTTACAAATCTAGGACACGCGGACCCAGATATCATCGAAGCTGTTCGCTCTCAAGCGGACCAACTCTTT
CACACCTCCAATCTTTTTTACTCTGAAGAAGCGGCAAAACTCGCAGAACTTCTGATCTTAAATTCTTTTCCGGGAAAAGT
GTTTTTAACCAATTCCGGAACCGAAGCCATAGAAGGAGCGTTTAAACTCGCAAGAAAATACGCATATTCGAAAAGTATCA
TGGACCCGATTATCCTTTCCTTAGAAAAAAGTTTTCATGGAAGATCCGTTTCCGGTATGAGTTTAACCGGACAAGATAAA
ATCAGAAAAGGTTACGGAGAACTTCTAAAAGGAATCGAGTTCATAGAACCGAACAACGACGAAGCCCTTGTCGCGGCTTT
CGAAAGACACCAGGGAAGAATCGTCGCATTGATCGAAGAACCAATCTTAGGTGAAAGCGGAATCATTCCCTTATCGAAGA
GCTTTCTCACACTTTCCAGAGAACTGACCGAAGAAAACGACGCGCTTCTTATCTTCGACGAAATCCAAACCGGAATGGGG
AGAACAGGAACATTATTCGCTTTTGAAACGATGGGATTTGCGCCCGACGCGATGACACTTGCCAAAGGACTCGGATCCGG
TTTTCCAATCGGCGCCCTAATCGTGGGAGAAAAATATCAGAATCTTTTTACGCCAGGATCCCACGGCTCCACATTCGGAG
GAAATCATCTTGCGGCAGCAATCGCTTACGAAACGATTCGAATCATTCAAACCAGAGAAATTTTAAACAACGTAAATCTT
TGTTCCGATATAGCTTTTACGAGACTGAAAGAAATGCAGGAAAAATATCCGGTGATCTCCGAAGTCAGAGGGAAAGGACT
TCATATCGGAGTCGAATTGAAAACTCCTTCCAGACCGGTGGTAGAGGCTTGTTTGTCTGCGGGGCTCGTAATAAACGCAA
CGGCGGATAACGTGATTCGAATCATGCCCTCACTTACGATTTCCACAGACTTTTTAAATCAGGGATTGGACATTTTAGAA
TCCGTACTCAAACAAAATTAA

Upstream 100 bases:

>100_bases
AAGCTCCTAATTCCAAAGGAGAAATTCCAATCCTCATGAAAGATCTCCTTTCCGAAATCAAAGTATCCGAGGAAATATTT
TTACGACTGGCGGAACTCTC

Downstream 100 bases:

>100_bases
AAGGATCCAAAAAAAGAATGAAGAATGTAGCGGTACTTTCCGGAGACGGAATCGGACCGGAAGTCATGGAAGTAGCCCTC
TCCGTTTTGAAAAAGGCTCT

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MNDTDIHKELFQHTKELADHYLLNTYSRYDVAFRYGVNELLFDFDNKQYIDFHCGVAVTNLGHADPDIIEAVRSQADQLF
HTSNLFYSEEAAKLAELLILNSFPGKVFLTNSGTEAIEGAFKLARKYAYSKSIMDPIILSLEKSFHGRSVSGMSLTGQDK
IRKGYGELLKGIEFIEPNNDEALVAAFERHQGRIVALIEEPILGESGIIPLSKSFLTLSRELTEENDALLIFDEIQTGMG
RTGTLFAFETMGFAPDAMTLAKGLGSGFPIGALIVGEKYQNLFTPGSHGSTFGGNHLAAAIAYETIRIIQTREILNNVNL
CSDIAFTRLKEMQEKYPVISEVRGKGLHIGVELKTPSRPVVEACLSAGLVINATADNVIRIMPSLTISTDFLNQGLDILE
SVLKQN

Sequences:

>Translated_406_residues
MNDTDIHKELFQHTKELADHYLLNTYSRYDVAFRYGVNELLFDFDNKQYIDFHCGVAVTNLGHADPDIIEAVRSQADQLF
HTSNLFYSEEAAKLAELLILNSFPGKVFLTNSGTEAIEGAFKLARKYAYSKSIMDPIILSLEKSFHGRSVSGMSLTGQDK
IRKGYGELLKGIEFIEPNNDEALVAAFERHQGRIVALIEEPILGESGIIPLSKSFLTLSRELTEENDALLIFDEIQTGMG
RTGTLFAFETMGFAPDAMTLAKGLGSGFPIGALIVGEKYQNLFTPGSHGSTFGGNHLAAAIAYETIRIIQTREILNNVNL
CSDIAFTRLKEMQEKYPVISEVRGKGLHIGVELKTPSRPVVEACLSAGLVINATADNVIRIMPSLTISTDFLNQGLDILE
SVLKQN
>Mature_406_residues
MNDTDIHKELFQHTKELADHYLLNTYSRYDVAFRYGVNELLFDFDNKQYIDFHCGVAVTNLGHADPDIIEAVRSQADQLF
HTSNLFYSEEAAKLAELLILNSFPGKVFLTNSGTEAIEGAFKLARKYAYSKSIMDPIILSLEKSFHGRSVSGMSLTGQDK
IRKGYGELLKGIEFIEPNNDEALVAAFERHQGRIVALIEEPILGESGIIPLSKSFLTLSRELTEENDALLIFDEIQTGMG
RTGTLFAFETMGFAPDAMTLAKGLGSGFPIGALIVGEKYQNLFTPGSHGSTFGGNHLAAAIAYETIRIIQTREILNNVNL
CSDIAFTRLKEMQEKYPVISEVRGKGLHIGVELKTPSRPVVEACLSAGLVINATADNVIRIMPSLTISTDFLNQGLDILE
SVLKQN

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=391, Percent_Identity=31.2020460358056, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI13994255, Length=441, Percent_Identity=29.0249433106576, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI284507298, Length=303, Percent_Identity=32.013201320132, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI37574042, Length=412, Percent_Identity=25.4854368932039, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI24119277, Length=404, Percent_Identity=24.009900990099, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI226442705, Length=412, Percent_Identity=24.7572815533981, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI226442709, Length=390, Percent_Identity=25.1282051282051, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI188536080, Length=300, Percent_Identity=25.6666666666667, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI38679950, Length=300, Percent_Identity=25.6666666666667, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI38679946, Length=300, Percent_Identity=25.6666666666667, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1788044, Length=389, Percent_Identity=38.3033419023136, Blast_Score=264, Evalue=7e-72,
Organism=Escherichia coli, GI1789759, Length=388, Percent_Identity=38.4020618556701, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI145693181, Length=410, Percent_Identity=33.6585365853659, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1789016, Length=399, Percent_Identity=31.077694235589, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1787560, Length=395, Percent_Identity=30.379746835443, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI1786991, Length=298, Percent_Identity=28.8590604026846, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786349, Length=277, Percent_Identity=29.6028880866426, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI25144271, Length=399, Percent_Identity=30.0751879699248, Blast_Score=191, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI32564660, Length=436, Percent_Identity=30.045871559633, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI25144274, Length=267, Percent_Identity=29.5880149812734, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71992977, Length=419, Percent_Identity=25.5369928400955, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71981843, Length=175, Percent_Identity=29.1428571428571, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17541228, Length=460, Percent_Identity=23.695652173913, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324432, Length=397, Percent_Identity=38.2871536523929, Blast_Score=273, Evalue=3e-74,
Organism=Saccharomyces cerevisiae, GI6323470, Length=415, Percent_Identity=31.8072289156626, Blast_Score=190, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6324386, Length=441, Percent_Identity=26.530612244898, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321456, Length=433, Percent_Identity=25.1732101616628, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21357415, Length=391, Percent_Identity=30.690537084399, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI28574759, Length=417, Percent_Identity=28.7769784172662, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI161085790, Length=422, Percent_Identity=28.436018957346, Blast_Score=172, Evalue=5e-43,
Organism=Drosophila melanogaster, GI21356575, Length=399, Percent_Identity=24.5614035087719, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281366494, Length=294, Percent_Identity=24.4897959183673, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24667139, Length=294, Percent_Identity=24.4897959183673, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24667143, Length=294, Percent_Identity=24.4897959183673, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 44792; Mature: 44792

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTDIHKELFQHTKELADHYLLNTYSRYDVAFRYGVNELLFDFDNKQYIDFHCGVAVTN
CCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCHHHHHHCCCCCEEEEEECCEEEEC
LGHADPDIIEAVRSQADQLFHTSNLFYSEEAAKLAELLILNSFPGKVFLTNSGTEAIEGA
CCCCCHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHH
FKLARKYAYSKSIMDPIILSLEKSFHGRSVSGMSLTGQDKIRKGYGELLKGIEFIEPNND
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHCCEEECCCCC
EALVAAFERHQGRIVALIEEPILGESGIIPLSKSFLTLSRELTEENDALLIFDEIQTGMG
CHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHHCCCC
RTGTLFAFETMGFAPDAMTLAKGLGSGFPIGALIVGEKYQNLFTPGSHGSTFGGNHLAAA
CCCEEEEEECCCCCCHHHHHHHHCCCCCCEEEEEECCHHHHCCCCCCCCCCCCCCHHHHH
IAYETIRIIQTREILNNVNLCSDIAFTRLKEMQEKYPVISEVRGKGLHIGVELKTPSRPV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEEEECCCCCHH
VEACLSAGLVINATADNVIRIMPSLTISTDFLNQGLDILESVLKQN
HHHHHHCCEEEEECCCCCEECCCCCEEEHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure
MNDTDIHKELFQHTKELADHYLLNTYSRYDVAFRYGVNELLFDFDNKQYIDFHCGVAVTN
CCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCHHHHHHCCCCCEEEEEECCEEEEC
LGHADPDIIEAVRSQADQLFHTSNLFYSEEAAKLAELLILNSFPGKVFLTNSGTEAIEGA
CCCCCHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHH
FKLARKYAYSKSIMDPIILSLEKSFHGRSVSGMSLTGQDKIRKGYGELLKGIEFIEPNND
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHCCEEECCCCC
EALVAAFERHQGRIVALIEEPILGESGIIPLSKSFLTLSRELTEENDALLIFDEIQTGMG
CHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHHCCCC
RTGTLFAFETMGFAPDAMTLAKGLGSGFPIGALIVGEKYQNLFTPGSHGSTFGGNHLAAA
CCCEEEEEECCCCCCHHHHHHHHCCCCCCEEEEEECCHHHHCCCCCCCCCCCCCCHHHHH
IAYETIRIIQTREILNNVNLCSDIAFTRLKEMQEKYPVISEVRGKGLHIGVELKTPSRPV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEEEECCCCCHH
VEACLSAGLVINATADNVIRIMPSLTISTDFLNQGLDILESVLKQN
HHHHHHCCEEEEECCCCCEECCCCCEEEHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA