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The map label for this gene is qmcA [H]

Identifier: 116328054

GI number: 116328054

Start: 1582973

End: 1583920

Strand: Reverse

Name: qmcA [H]

Synonym: LBL_1349

Alternate gene names: 116328054

Gene position: 1583920-1582973 (Counterclockwise)

Preceding gene: 116328055

Following gene: 116328053

Centisome position: 43.82

GC content: 45.25

Gene sequence:

>948_bases
ATGTCTGCAGGGTTTATATTCACGTTAGTCTTCATAGCGTTGATCTATCTGATTCGTAAAACATTCATCATCGTTCCTCA
ACAGTATTGTTATGTCGTGGAACGAGTCGGAGTTTTTAAAGGAGCCTTGGAAGCAGGTTTTCATTTTCTCTGGCCCGTGA
TCGAAGTTGTCAAATACAGGCAGAATCTCAAAGAGATCGCGATCGACATTCCTCCTCAGATGTGTATCACAAAGGACAAC
GTCTCCATCGCGGTGGATGGAATTCTTTATTTGAAAGTGGTCGATCCCTATAAAGCTTCTTACGCGATCGAAAACTTTAT
GCTCGCGACGCAGCAGCTCGCTCAGACGACCCTTCGTTCCGAAATCGGTAAACTGATTCTTGATCAGACATTTGCGGAAA
GAGACGATATCAATTCCCACGTTGTGCGTGCGTTGGACGAAGCGACCGATCCCTGGGGAATCAAGGTCACGAGGTACGAA
ATCAAAAATATTTCTCCTCCTAAGGAAATTCTTCACGAGATGGAAGAACAAGTAAAAGCGGAACGCGTAAAAAGGGCGGA
GATCACGATCTCGGAAGGAGAAAAACTTTCGAGGATCAACCGCTCCGTGGGGGAAAAGGAAGAAGCCATCAACGTTTCCG
AAGGTGAAAAAATGAAAAAAATCAACGAAGCAGAAGGTAAGGCTTTGGAGATAGAGCTGATTGCCGCCGCGAAAGCAAAA
GGAATCCGGATGATCGCAGAATCCATTTCCAGAGAAGGCGGAGGCGAAGCTGTTAATCTCCAAATTACCGAAGATTATCT
CACTGGTCTTGGAGAAATCCTAAGCGTTTCCAAAACTACGATTCTTCCCGCGGAGCTTGCCAATATTGCGGGAGTGTTCG
AAGGTTTTTCCAAAGTAACCGGAAAATTACCGGAAATCAAAACACCGAAAGAGAAGGAAGGTCAGTAA

Upstream 100 bases:

>100_bases
CAAGGCAAGAATTCTGAGCCGAGACAACCTCACGTTTCTCGTGGAACCTTTGGAACTTCCGGAAGAATAGGTCTGATTTT
AAAATAGAAAAGGAGATTTT

Downstream 100 bases:

>100_bases
GATGGAAACGTTTCAAAACACATTCGTAATGATATTCTGGACTCTGTTCGGAATCTACTTCGCATACAAACTCTATCGTT
CGATCCGAATCGTTTCCGCT

Product: HflC membrane associated protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MSAGFIFTLVFIALIYLIRKTFIIVPQQYCYVVERVGVFKGALEAGFHFLWPVIEVVKYRQNLKEIAIDIPPQMCITKDN
VSIAVDGILYLKVVDPYKASYAIENFMLATQQLAQTTLRSEIGKLILDQTFAERDDINSHVVRALDEATDPWGIKVTRYE
IKNISPPKEILHEMEEQVKAERVKRAEITISEGEKLSRINRSVGEKEEAINVSEGEKMKKINEAEGKALEIELIAAAKAK
GIRMIAESISREGGGEAVNLQITEDYLTGLGEILSVSKTTILPAELANIAGVFEGFSKVTGKLPEIKTPKEKEGQ

Sequences:

>Translated_315_residues
MSAGFIFTLVFIALIYLIRKTFIIVPQQYCYVVERVGVFKGALEAGFHFLWPVIEVVKYRQNLKEIAIDIPPQMCITKDN
VSIAVDGILYLKVVDPYKASYAIENFMLATQQLAQTTLRSEIGKLILDQTFAERDDINSHVVRALDEATDPWGIKVTRYE
IKNISPPKEILHEMEEQVKAERVKRAEITISEGEKLSRINRSVGEKEEAINVSEGEKMKKINEAEGKALEIELIAAAKAK
GIRMIAESISREGGGEAVNLQITEDYLTGLGEILSVSKTTILPAELANIAGVFEGFSKVTGKLPEIKTPKEKEGQ
>Mature_314_residues
SAGFIFTLVFIALIYLIRKTFIIVPQQYCYVVERVGVFKGALEAGFHFLWPVIEVVKYRQNLKEIAIDIPPQMCITKDNV
SIAVDGILYLKVVDPYKASYAIENFMLATQQLAQTTLRSEIGKLILDQTFAERDDINSHVVRALDEATDPWGIKVTRYEI
KNISPPKEILHEMEEQVKAERVKRAEITISEGEKLSRINRSVGEKEEAINVSEGEKMKKINEAEGKALEIELIAAAKAKG
IRMIAESISREGGGEAVNLQITEDYLTGLGEILSVSKTTILPAELANIAGVFEGFSKVTGKLPEIKTPKEKEGQ

Specific function: Unknown

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family [H]

Homologues:

Organism=Homo sapiens, GI7305503, Length=294, Percent_Identity=42.5170068027211, Blast_Score=237, Evalue=1e-62,
Organism=Homo sapiens, GI38016911, Length=215, Percent_Identity=34.8837209302326, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI221316744, Length=190, Percent_Identity=33.6842105263158, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI21686995, Length=190, Percent_Identity=33.6842105263158, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI7657615, Length=185, Percent_Identity=27.5675675675676, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1786697, Length=297, Percent_Identity=36.3636363636364, Blast_Score=202, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI32564147, Length=267, Percent_Identity=46.4419475655431, Blast_Score=240, Evalue=6e-64,
Organism=Caenorhabditis elegans, GI17569499, Length=218, Percent_Identity=34.4036697247706, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71987612, Length=222, Percent_Identity=31.0810810810811, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71989948, Length=166, Percent_Identity=36.7469879518072, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71989955, Length=166, Percent_Identity=36.7469879518072, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25153583, Length=222, Percent_Identity=31.0810810810811, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17569493, Length=189, Percent_Identity=31.2169312169312, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71987621, Length=222, Percent_Identity=31.0810810810811, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI193209764, Length=189, Percent_Identity=31.2169312169312, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI193210507, Length=185, Percent_Identity=33.5135135135135, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17570161, Length=185, Percent_Identity=33.5135135135135, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI32566490, Length=200, Percent_Identity=34, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17569497, Length=133, Percent_Identity=34.5864661654135, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17570459, Length=219, Percent_Identity=31.9634703196347, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71989963, Length=110, Percent_Identity=32.7272727272727, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45550506, Length=274, Percent_Identity=42.7007299270073, Blast_Score=226, Evalue=1e-59,
Organism=Drosophila melanogaster, GI45556022, Length=211, Percent_Identity=34.5971563981043, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI18860517, Length=204, Percent_Identity=34.3137254901961, Blast_Score=104, Evalue=8e-23,
Organism=Drosophila melanogaster, GI62484448, Length=207, Percent_Identity=34.7826086956522, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI281365664, Length=207, Percent_Identity=34.7826086956522, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI62484274, Length=207, Percent_Identity=34.7826086956522, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24657857, Length=214, Percent_Identity=34.5794392523364, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21356845, Length=188, Percent_Identity=27.6595744680851, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281361633, Length=192, Percent_Identity=26.5625, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281361631, Length=192, Percent_Identity=26.5625, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28573263, Length=150, Percent_Identity=29.3333333333333, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI281361635, Length=126, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR018080
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 35115; Mature: 34984

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAGFIFTLVFIALIYLIRKTFIIVPQQYCYVVERVGVFKGALEAGFHFLWPVIEVVKYR
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNLKEIAIDIPPQMCITKDNVSIAVDGILYLKVVDPYKASYAIENFMLATQQLAQTTLRS
HHHHHHHHCCCCCCEEECCCCEEEECCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
EIGKLILDQTFAERDDINSHVVRALDEATDPWGIKVTRYEIKNISPPKEILHEMEEQVKA
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
ERVKRAEITISEGEKLSRINRSVGEKEEAINVSEGEKMKKINEAEGKALEIELIAAAKAK
HHHHHHEEEECCCHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHCCCCEEEEEEEEHHHHH
GIRMIAESISREGGGEAVNLQITEDYLTGLGEILSVSKTTILPAELANIAGVFEGFSKVT
HHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GKLPEIKTPKEKEGQ
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
SAGFIFTLVFIALIYLIRKTFIIVPQQYCYVVERVGVFKGALEAGFHFLWPVIEVVKYR
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNLKEIAIDIPPQMCITKDNVSIAVDGILYLKVVDPYKASYAIENFMLATQQLAQTTLRS
HHHHHHHHCCCCCCEEECCCCEEEECCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
EIGKLILDQTFAERDDINSHVVRALDEATDPWGIKVTRYEIKNISPPKEILHEMEEQVKA
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
ERVKRAEITISEGEKLSRINRSVGEKEEAINVSEGEKMKKINEAEGKALEIELIAAAKAK
HHHHHHEEEECCCHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHCCCCEEEEEEEEHHHHH
GIRMIAESISREGGGEAVNLQITEDYLTGLGEILSVSKTTILPAELANIAGVFEGFSKVT
HHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GKLPEIKTPKEKEGQ
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]