Click here to switch to the map view.

The map label for this gene is tlpA [H]

Identifier: 116327853

GI number: 116327853

Start: 1333146

End: 1335686

Strand: Reverse

Name: tlpA [H]

Synonym: LBL_1131

Alternate gene names: 116327853

Gene position: 1335686-1333146 (Counterclockwise)

Preceding gene: 116327854

Following gene: 116327852

Centisome position: 36.95

GC content: 39.16

Gene sequence:

>2541_bases
ATGGATGACAACATTACAAATTCGATTCGTAAATTCATTCTTCATTTCATTTTGATAACCGAAGTCGTAGGTTTTACTCT
TACGATAGGTACGGCGATTTTATTTTATAAAATGTTTTTGGAAATGGATTCCGGCCAACTTGAAATCGCAATCTATATCA
CTTTAGCAACTTCAGTTTTCACCCTTATATTCGCGGTTTTTTCGGATATGCGCAGACTTCGGCCTATTCAAAAGTATCTT
TTTATCACGGAAAGAGGTATCGCAGATAAAGAGATCATCTTAAAGGCGCAAAAATCCGTTTTTCGTATTCCTTTTTTTCA
TTCAGTCGAAATCGGTCTTCGAATTTTAATCACTGCCTTCGTCGTAATCACCATCCTCGGCCGATTTGTGGTCTTAGATG
CGACTGATTACTACAATCTGTATGCGATCACTCTCCTCATGTCTCTTTTTATGGGAGTGTACACGTTTTTAGTCTCAGAA
AAATTGACTTCCAATCTGATAGAAGCCGGTATATTCAAAAATATAGACGTCTCATCTCTGGTAAAAATTCGCCTAACAGG
CTCGCTTACGATAACCTTTATATTTATCATGTGTATCCTTGCGATTACGATCTCCTGTCTCGTATTCAAGTTCAACCATT
TGGCGATTCAAAGATCGTATTTCAATCAGATGGAAAACATGAATGAAACGCTGAATATTTTTACGGAATCGATCTTCGAA
GAAGTTCAATTCGACGCGCAAAAATTGAAAAAAAACCCCTTATTCCTTTCTCTAATCGAGAATCACAAAACAAACGAAAT
TCAGAAATTTTTAGATACACTTTTAGACCATTCTCCGAAATACGAATCCATTTCTCTTATCAAACAGGAAAATCAATCCT
GGAATGTTTTCATAGGTACCGGAATACTTTCCAAAGACCGCGAATCCATTCTCAAAGATTTCAAACTTCCTTCGAAAGAT
ATCATCATAGAAACGATTTCAAGAAAAAGAATATTCCTAAGCGAACCGATCTCCTCTCCCATTTCCGGAACACCCATACT
TTTAATTTTGGAAACGATTCCGCAGAACGTAAATGTTTACATCGCTTATTCCCTTAGAATCGCCGATCTTACGAGTAAAC
TAATCGGTTCTATTCAGATCGGAAAATCGGGTTATTCCGGACTTATTAGTCCGAACGAAGTGATAATCAATCACATTAAC
CCTTCTCTGAATCTGAAAAGTTTGAAAAGTTTCCCTTTCTATCCCCAAATGAAAAATTATAAGAACAAAGTTCCGTTTCG
TTATCTTTTTAACGGGAAATACAAATACACGATTCTTTATAAGAGTCCGAAATACGATTTTCTTACGTTTACTTCGGTCG
AATGTGAAGAAATCACCGGCGAAGCGATCGTCTGCGTTTACGCAATGGTGGGAATTTCCTTAGCCGGTCTTTTTCTAATA
GGAATTTTAATCTATTTCATTCTTAAAAAGAGAATCCGTCCTTTGCAAGAAAGTAAGAACGCCTTGGAAGCTATGGCGAA
TGGGAATCTTACCAACGGACTCAAGGTTTTTTCAATGGATGAAATCGGAGAGATGGCGATTTCAATCAATTCGTTTAACA
AAAATGTGAAAAAGGTCTTGAATAAGATCGCAAACTCGTCCGAAAACCTTGCAAGCTCCTCCGACGAGATGTCGAAAGCC
CACCACTCCATTTCCGATAACGCGCAAAACCAGGCTTCTTCTTCGGAAGAAATTTCAGCTTCGATCGAAGAAATCTCCGC
CGGTATGGATGGAATGGAAATCCAGACGGAGGAGCAAGTCAATCTACTGGATCAATTCGCTTTGGATATGAGTCAATTCT
CACATTCCATTCACGCAACTTTTAAAAGTTTGGAAAAGACGATGTCCGAAATGGAAAGGATCACGGGAAGCGCTCAAAAG
GGTGAAAAATCCTTGGAGCTGACCAATCATTCCATCGCTAAGATCAGCCGTAGTTCGGAAGATATTACCGGCGTCATAGA
AATCATCAGCAATATTTCAGAACAAATTCATCTTCTCTCATTGAATACGGCAATCGAAGCCGCCAGAGCCGGGAGCGCCG
GAAGAGGTTTTGCGGTCGTCGCCGATGAAATTTCGAAACTAGCGGATAAAACGACGGACAGCATCAAAAATATAGAATAC
ATCATTCAAAACAACGAAACGGAAATAGGAATCGGAATTCAAAATATCACCGATACGGTAAAAGTCATCTCCGGAATCAT
CCAAGGGATTTCTGAAATCAATCACCAAATGAAGGTGGTAAATCGGTTTATGGAAGATCAACTTTCCAAAAACGATCAAA
TGAACCTCGCCGCGAAAGAAGTCAAAGGCAGGGCGGATGCAATCCAAGCGGCGGTTCGTGAACAAAAAATTGCAATTGAA
GAAATCTCTAAAAGGATCACTACTATAAACGAGCTCAATCAATCTTCCGCGGCTTCCTCGGAAGAACTGAGTTCCAGTTC
TGTCAACTTAGCAAAATTAGCCGAAGAGCTTAAACACGAAGTAGAATTTTTTAAACTTTGA

Upstream 100 bases:

>100_bases
TTTTTACTTTCTCCTTGTATTAATAATCGTTAATAGCTTTAATTTACATAGAGGATCAATCAAGTTCGAATAACGCATAA
CTTAGGTATCGGAACAAAAT

Downstream 100 bases:

>100_bases
TTTCGTAAGAAAACAAAAAACGGATGTTCTTTTTTCGCATCCTGCGACGAAATCAAAATTGTGAATCGTTGTCTTCCGTG
ATTCATAACTGATTCGGAAA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 846; Mature: 846

Protein sequence:

>846_residues
MDDNITNSIRKFILHFILITEVVGFTLTIGTAILFYKMFLEMDSGQLEIAIYITLATSVFTLIFAVFSDMRRLRPIQKYL
FITERGIADKEIILKAQKSVFRIPFFHSVEIGLRILITAFVVITILGRFVVLDATDYYNLYAITLLMSLFMGVYTFLVSE
KLTSNLIEAGIFKNIDVSSLVKIRLTGSLTITFIFIMCILAITISCLVFKFNHLAIQRSYFNQMENMNETLNIFTESIFE
EVQFDAQKLKKNPLFLSLIENHKTNEIQKFLDTLLDHSPKYESISLIKQENQSWNVFIGTGILSKDRESILKDFKLPSKD
IIIETISRKRIFLSEPISSPISGTPILLILETIPQNVNVYIAYSLRIADLTSKLIGSIQIGKSGYSGLISPNEVIINHIN
PSLNLKSLKSFPFYPQMKNYKNKVPFRYLFNGKYKYTILYKSPKYDFLTFTSVECEEITGEAIVCVYAMVGISLAGLFLI
GILIYFILKKRIRPLQESKNALEAMANGNLTNGLKVFSMDEIGEMAISINSFNKNVKKVLNKIANSSENLASSSDEMSKA
HHSISDNAQNQASSSEEISASIEEISAGMDGMEIQTEEQVNLLDQFALDMSQFSHSIHATFKSLEKTMSEMERITGSAQK
GEKSLELTNHSIAKISRSSEDITGVIEIISNISEQIHLLSLNTAIEAARAGSAGRGFAVVADEISKLADKTTDSIKNIEY
IIQNNETEIGIGIQNITDTVKVISGIIQGISEINHQMKVVNRFMEDQLSKNDQMNLAAKEVKGRADAIQAAVREQKIAIE
EISKRITTINELNQSSAASSEELSSSSVNLAKLAEELKHEVEFFKL

Sequences:

>Translated_846_residues
MDDNITNSIRKFILHFILITEVVGFTLTIGTAILFYKMFLEMDSGQLEIAIYITLATSVFTLIFAVFSDMRRLRPIQKYL
FITERGIADKEIILKAQKSVFRIPFFHSVEIGLRILITAFVVITILGRFVVLDATDYYNLYAITLLMSLFMGVYTFLVSE
KLTSNLIEAGIFKNIDVSSLVKIRLTGSLTITFIFIMCILAITISCLVFKFNHLAIQRSYFNQMENMNETLNIFTESIFE
EVQFDAQKLKKNPLFLSLIENHKTNEIQKFLDTLLDHSPKYESISLIKQENQSWNVFIGTGILSKDRESILKDFKLPSKD
IIIETISRKRIFLSEPISSPISGTPILLILETIPQNVNVYIAYSLRIADLTSKLIGSIQIGKSGYSGLISPNEVIINHIN
PSLNLKSLKSFPFYPQMKNYKNKVPFRYLFNGKYKYTILYKSPKYDFLTFTSVECEEITGEAIVCVYAMVGISLAGLFLI
GILIYFILKKRIRPLQESKNALEAMANGNLTNGLKVFSMDEIGEMAISINSFNKNVKKVLNKIANSSENLASSSDEMSKA
HHSISDNAQNQASSSEEISASIEEISAGMDGMEIQTEEQVNLLDQFALDMSQFSHSIHATFKSLEKTMSEMERITGSAQK
GEKSLELTNHSIAKISRSSEDITGVIEIISNISEQIHLLSLNTAIEAARAGSAGRGFAVVADEISKLADKTTDSIKNIEY
IIQNNETEIGIGIQNITDTVKVISGIIQGISEINHQMKVVNRFMEDQLSKNDQMNLAAKEVKGRADAIQAAVREQKIAIE
EISKRITTINELNQSSAASSEELSSSSVNLAKLAEELKHEVEFFKL
>Mature_846_residues
MDDNITNSIRKFILHFILITEVVGFTLTIGTAILFYKMFLEMDSGQLEIAIYITLATSVFTLIFAVFSDMRRLRPIQKYL
FITERGIADKEIILKAQKSVFRIPFFHSVEIGLRILITAFVVITILGRFVVLDATDYYNLYAITLLMSLFMGVYTFLVSE
KLTSNLIEAGIFKNIDVSSLVKIRLTGSLTITFIFIMCILAITISCLVFKFNHLAIQRSYFNQMENMNETLNIFTESIFE
EVQFDAQKLKKNPLFLSLIENHKTNEIQKFLDTLLDHSPKYESISLIKQENQSWNVFIGTGILSKDRESILKDFKLPSKD
IIIETISRKRIFLSEPISSPISGTPILLILETIPQNVNVYIAYSLRIADLTSKLIGSIQIGKSGYSGLISPNEVIINHIN
PSLNLKSLKSFPFYPQMKNYKNKVPFRYLFNGKYKYTILYKSPKYDFLTFTSVECEEITGEAIVCVYAMVGISLAGLFLI
GILIYFILKKRIRPLQESKNALEAMANGNLTNGLKVFSMDEIGEMAISINSFNKNVKKVLNKIANSSENLASSSDEMSKA
HHSISDNAQNQASSSEEISASIEEISAGMDGMEIQTEEQVNLLDQFALDMSQFSHSIHATFKSLEKTMSEMERITGSAQK
GEKSLELTNHSIAKISRSSEDITGVIEIISNISEQIHLLSLNTAIEAARAGSAGRGFAVVADEISKLADKTTDSIKNIEY
IIQNNETEIGIGIQNITDTVKVISGIIQGISEINHQMKVVNRFMEDQLSKNDQMNLAAKEVKGRADAIQAAVREQKIAIE
EISKRITTINELNQSSAASSEELSSSSVNLAKLAEELKHEVEFFKL

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=383, Percent_Identity=26.8929503916449, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI2367378, Length=317, Percent_Identity=25.2365930599369, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1788195, Length=297, Percent_Identity=25.2525252525253, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI1788194, Length=363, Percent_Identity=22.8650137741047, Blast_Score=106, Evalue=7e-24,
Organism=Escherichia coli, GI1789453, Length=246, Percent_Identity=23.1707317073171, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 94901; Mature: 94901

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDNITNSIRKFILHFILITEVVGFTLTIGTAILFYKMFLEMDSGQLEIAIYITLATSVF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHH
TLIFAVFSDMRRLRPIQKYLFITERGIADKEIILKAQKSVFRIPFFHSVEIGLRILITAF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHH
VVITILGRFVVLDATDYYNLYAITLLMSLFMGVYTFLVSEKLTSNLIEAGIFKNIDVSSL
HHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHE
VKIRLTGSLTITFIFIMCILAITISCLVFKFNHLAIQRSYFNQMENMNETLNIFTESIFE
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVQFDAQKLKKNPLFLSLIENHKTNEIQKFLDTLLDHSPKYESISLIKQENQSWNVFIGT
HHHHHHHHHCCCCEEEEEHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEEC
GILSKDRESILKDFKLPSKDIIIETISRKRIFLSEPISSPISGTPILLILETIPQNVNVY
CCCCHHHHHHHHHCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEECCCCCCEEE
IAYSLRIADLTSKLIGSIQIGKSGYSGLISPNEVIINHINPSLNLKSLKSFPFYPQMKNY
EEEEEEHHHHHHHHHCCEEECCCCCCCCCCCCHHEEECCCCCCCHHHHHCCCCCCCHHCC
KNKVPFRYLFNGKYKYTILYKSPKYDFLTFTSVECEEITGEAIVCVYAMVGISLAGLFLI
CCCCCEEEEECCEEEEEEEEECCCCCEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHH
GILIYFILKKRIRPLQESKNALEAMANGNLTNGLKVFSMDEIGEMAISINSFNKNVKKVL
HHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHEEEHHHHHHHHHHHH
NKIANSSENLASSSDEMSKAHHSISDNAQNQASSSEEISASIEEISAGMDGMEIQTEEQV
HHHHCCCHHHCCCHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHCCCCCCEECCHHHH
NLLDQFALDMSQFSHSIHATFKSLEKTMSEMERITGSAQKGEKSLELTNHSIAKISRSSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHCCHHHHHHHCCCH
DITGVIEIISNISEQIHLLSLNTAIEAARAGSAGRGFAVVADEISKLADKTTDSIKNIEY
HHHHHHHHHHHHHHHEEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IIQNNETEIGIGIQNITDTVKVISGIIQGISEINHQMKVVNRFMEDQLSKNDQMNLAAKE
EEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
VKGRADAIQAAVREQKIAIEEISKRITTINELNQSSAASSEELSSSSVNLAKLAEELKHE
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHH
VEFFKL
HHHHCC
>Mature Secondary Structure
MDDNITNSIRKFILHFILITEVVGFTLTIGTAILFYKMFLEMDSGQLEIAIYITLATSVF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHH
TLIFAVFSDMRRLRPIQKYLFITERGIADKEIILKAQKSVFRIPFFHSVEIGLRILITAF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHH
VVITILGRFVVLDATDYYNLYAITLLMSLFMGVYTFLVSEKLTSNLIEAGIFKNIDVSSL
HHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHE
VKIRLTGSLTITFIFIMCILAITISCLVFKFNHLAIQRSYFNQMENMNETLNIFTESIFE
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVQFDAQKLKKNPLFLSLIENHKTNEIQKFLDTLLDHSPKYESISLIKQENQSWNVFIGT
HHHHHHHHHCCCCEEEEEHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEEC
GILSKDRESILKDFKLPSKDIIIETISRKRIFLSEPISSPISGTPILLILETIPQNVNVY
CCCCHHHHHHHHHCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEECCCCCCEEE
IAYSLRIADLTSKLIGSIQIGKSGYSGLISPNEVIINHINPSLNLKSLKSFPFYPQMKNY
EEEEEEHHHHHHHHHCCEEECCCCCCCCCCCCHHEEECCCCCCCHHHHHCCCCCCCHHCC
KNKVPFRYLFNGKYKYTILYKSPKYDFLTFTSVECEEITGEAIVCVYAMVGISLAGLFLI
CCCCCEEEEECCEEEEEEEEECCCCCEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHH
GILIYFILKKRIRPLQESKNALEAMANGNLTNGLKVFSMDEIGEMAISINSFNKNVKKVL
HHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHEEEHHHHHHHHHHHH
NKIANSSENLASSSDEMSKAHHSISDNAQNQASSSEEISASIEEISAGMDGMEIQTEEQV
HHHHCCCHHHCCCHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHCCCCCCEECCHHHH
NLLDQFALDMSQFSHSIHATFKSLEKTMSEMERITGSAQKGEKSLELTNHSIAKISRSSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHCCHHHHHHHCCCH
DITGVIEIISNISEQIHLLSLNTAIEAARAGSAGRGFAVVADEISKLADKTTDSIKNIEY
HHHHHHHHHHHHHHHEEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IIQNNETEIGIGIQNITDTVKVISGIIQGISEINHQMKVVNRFMEDQLSKNDQMNLAAKE
EEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
VKGRADAIQAAVREQKIAIEEISKRITTINELNQSSAASSEELSSSSVNLAKLAEELKHE
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHH
VEFFKL
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]