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The map label for this gene is argF [H]

Identifier: 116327770

GI number: 116327770

Start: 1200357

End: 1201286

Strand: Reverse

Name: argF [H]

Synonym: LBL_1028

Alternate gene names: 116327770

Gene position: 1201286-1200357 (Counterclockwise)

Preceding gene: 116327771

Following gene: 116327769

Centisome position: 33.24

GC content: 42.58

Gene sequence:

>930_bases
ATGTCTGAAAGCAACATAAAACACTTGATTTCCTGGGAAGATTGGTCGGATTCCGAAATCCTTGATTTGGTGAACTTTGC
AGTTCATGTAAAGAAAAATCGAGTCAATTATGCGGGACATATGAGTGGCCGATCCCTCGCTATGCTCTTTCAGAAAACCT
CCACAAGAACCAGGGTTTCCTTTGAAGTCGCCATGACCGAAATGGGAGGGCACGGAATTTATCTAGATTGGATGGCGTCT
AACTTTCAACTTTCTGATATCGATCTAGAAGCCAGATATCTTTCCAGAAACGTATCCGTTATTATGGCCCGTTTGAAAAA
ACACGAGGATCTTCTTTTGATGAAAAACGGCTCTCAAGTTCCGGTCATTAACGGATGCGATAATATGTTTCATCCTTGTC
AATCTCTTGCGGATATTATGACGATCGCACTCGATGCCCCGGAACGTCCCCTCAACCAAACGAAACTGACTTACATCGGA
GTTCATAACAATGTGGTCAATTCCCTCATCGGAATCACTGCCGCACTCGGAGTCCATCTAACTCTCGTAACGCCAATCAA
AGAAAACATTCACCCCCAGACGGTGGAAAGAGCCAAGTCGAAAGGAACTCTTACTTGGGAACAAAATCTGGAAAAGTCGG
TAAAAGATGCGGACTATGTTTATACGGACACTTGGCTAGATATGGAATTTTTCAACGATCCTTCTTACGCAGATAAGAAA
AAACAAAGAATGGAGTTGATGATGCCGTATCAGATCAATTCTTCTTTGATGGAAAAAACGAATGCAAAAGTGATGCATGA
TATGCCGATCCACGCGGGTTATGAAATCACCAGAGAAGTCGTTTTAAGTCAACGATCCATCATCTTTCAGCAGGCAGAAA
ATCGTTTAGACGCCCAGAAAGCAGTCATTCTAAAACTTCTGGAAGTTTGA

Upstream 100 bases:

>100_bases
CGTATTTGTTGCCACTACGAGATCCGAATCTCGATTTTATTTTTTGGTCTTTTTCATTTACGAAACGACTCCGATTTTGT
TTTTTGTATATAAGACCCGT

Downstream 100 bases:

>100_bases
TACTTCGGAAAATCGGTTTACAGAGGCCCGCACTTTCGAAACCTGTATTTAGAGCCTTTTCACCCTCACTTGCAGGCTCG
AAACCACAATTAAAGGTATC

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSESNIKHLISWEDWSDSEILDLVNFAVHVKKNRVNYAGHMSGRSLAMLFQKTSTRTRVSFEVAMTEMGGHGIYLDWMAS
NFQLSDIDLEARYLSRNVSVIMARLKKHEDLLLMKNGSQVPVINGCDNMFHPCQSLADIMTIALDAPERPLNQTKLTYIG
VHNNVVNSLIGITAALGVHLTLVTPIKENIHPQTVERAKSKGTLTWEQNLEKSVKDADYVYTDTWLDMEFFNDPSYADKK
KQRMELMMPYQINSSLMEKTNAKVMHDMPIHAGYEITREVVLSQRSIIFQQAENRLDAQKAVILKLLEV

Sequences:

>Translated_309_residues
MSESNIKHLISWEDWSDSEILDLVNFAVHVKKNRVNYAGHMSGRSLAMLFQKTSTRTRVSFEVAMTEMGGHGIYLDWMAS
NFQLSDIDLEARYLSRNVSVIMARLKKHEDLLLMKNGSQVPVINGCDNMFHPCQSLADIMTIALDAPERPLNQTKLTYIG
VHNNVVNSLIGITAALGVHLTLVTPIKENIHPQTVERAKSKGTLTWEQNLEKSVKDADYVYTDTWLDMEFFNDPSYADKK
KQRMELMMPYQINSSLMEKTNAKVMHDMPIHAGYEITREVVLSQRSIIFQQAENRLDAQKAVILKLLEV
>Mature_308_residues
SESNIKHLISWEDWSDSEILDLVNFAVHVKKNRVNYAGHMSGRSLAMLFQKTSTRTRVSFEVAMTEMGGHGIYLDWMASN
FQLSDIDLEARYLSRNVSVIMARLKKHEDLLLMKNGSQVPVINGCDNMFHPCQSLADIMTIALDAPERPLNQTKLTYIGV
HNNVVNSLIGITAALGVHLTLVTPIKENIHPQTVERAKSKGTLTWEQNLEKSVKDADYVYTDTWLDMEFFNDPSYADKKK
QRMELMMPYQINSSLMEKTNAKVMHDMPIHAGYEITREVVLSQRSIIFQQAENRLDAQKAVILKLLEV

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=315, Percent_Identity=29.2063492063492, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI18105007, Length=312, Percent_Identity=26.2820512820513, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1786469, Length=337, Percent_Identity=32.3442136498516, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1790703, Length=333, Percent_Identity=32.4324324324324, Blast_Score=155, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6322373, Length=328, Percent_Identity=32.3170731707317, Blast_Score=144, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6322331, Length=314, Percent_Identity=24.203821656051, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24642586, Length=296, Percent_Identity=25.3378378378378, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 35246; Mature: 35115

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESNIKHLISWEDWSDSEILDLVNFAVHVKKNRVNYAGHMSGRSLAMLFQKTSTRTRVS
CCCCCCEEEEEECCCCCHHHHHHHHHHHEEECCCCCEEECCCCCHHEEEEHHCCCCEEEE
FEVAMTEMGGHGIYLDWMASNFQLSDIDLEARYLSRNVSVIMARLKKHEDLLLMKNGSQV
EEEEEEECCCCEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
PVINGCDNMFHPCQSLADIMTIALDAPERPLNQTKLTYIGVHNNVVNSLIGITAALGVHL
CEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHEEE
TLVTPIKENIHPQTVERAKSKGTLTWEQNLEKSVKDADYVYTDTWLDMEFFNDPSYADKK
EEEECHHHCCCHHHHHHHHHCCCEEHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCHHH
KQRMELMMPYQINSSLMEKTNAKVMHDMPIHAGYEITREVVLSQRSIIFQQAENRLDAQK
HHHHHEECCEECCHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVILKLLEV
HHHHHHHCC
>Mature Secondary Structure 
SESNIKHLISWEDWSDSEILDLVNFAVHVKKNRVNYAGHMSGRSLAMLFQKTSTRTRVS
CCCCCEEEEEECCCCCHHHHHHHHHHHEEECCCCCEEECCCCCHHEEEEHHCCCCEEEE
FEVAMTEMGGHGIYLDWMASNFQLSDIDLEARYLSRNVSVIMARLKKHEDLLLMKNGSQV
EEEEEEECCCCEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
PVINGCDNMFHPCQSLADIMTIALDAPERPLNQTKLTYIGVHNNVVNSLIGITAALGVHL
CEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHEEE
TLVTPIKENIHPQTVERAKSKGTLTWEQNLEKSVKDADYVYTDTWLDMEFFNDPSYADKK
EEEECHHHCCCHHHHHHHHHCCCEEHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCHHH
KQRMELMMPYQINSSLMEKTNAKVMHDMPIHAGYEITREVVLSQRSIIFQQAENRLDAQK
HHHHHEECCEECCHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVILKLLEV
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA