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The map label for this gene is dctR [H]

Identifier: 116327739

GI number: 116327739

Start: 1162221

End: 1163147

Strand: Reverse

Name: dctR [H]

Synonym: LBL_0995

Alternate gene names: 116327739

Gene position: 1163147-1162221 (Counterclockwise)

Preceding gene: 116327740

Following gene: 116327735

Centisome position: 32.18

GC content: 43.47

Gene sequence:

>927_bases
ATGGAAGATCCTATGCGAATTCTTTTTTTAGACGACGAGGAAATGATCCGAGAACTGTTTCAGGAGATATTCGGAGTCGT
TCATGACCTCACTTTGGCGGGAACTGCGGAAGAAGCTTTAGAAATCTGTAAAGACAAAAGTTTCGATCTGATCATAACGG
ACGTCCGTCTACCTAAAATGAGCGGGATCGATTTCGTTTCCAAGCTCCGGGACAGGGAAATCAACACTCCTTTTATCGTG
ATCACGGGCAACCAGGATATAGATATCTCCATTCGAGCGCTCCGGCTTGGTGCCGTGGATTTTTTCATCAAACCCTTTCG
TATGGATGCGATCCGTCATTCTCTGCAAAAATTCGAGAATTTATTCATTTGTAGTCAGGAACTGATCGGTAAAAACCACT
TTCAACTAACAGAGTCCAAACAACATTTTTCGATTAAACCCAGTCTTAAAAATTTAAATCAATATGTAAATCTTGTTATG
CGCTCGATTTCCCTGATTCCCGGAATTCATACGGACGACATCCTTTCAATCAAACTCGCTTTGTATGAACTGCTCGGAAA
TTCGATCGAACACGGGTTCGCGGGAATTAATTACGAAAATAAATCGAAATTACTCTCCTCCGATGTGGATTATTTCGATC
ACGTGGATCGGATCTGCGACACTCTGAGCGAATTCGTTCATCTTGAAGTCGGTTTCGAAAATCAAAAAGTTCACGTTTCT
CTAAAAGATCCTGGAACGGGTTTCGATCCCAGCAAGGTTCCCGACCCGGTCACCGATCCTAACGCAAGTCATCTCTCCGG
CCGCGGTATCTTCCTTGTGAAAATGAACGTGGATGAACTCGTCTACAACGACATCGGAAACGAAGTCAGATTCAGCAGAA
CCTTAAAAAAGGCTCTTCCTACGCCTTCAAAAGTAAATGCCAGCTGA

Upstream 100 bases:

>100_bases
CTTGAATTCAAAGATTCTCTCAAATTATAACCTGGATAAATTAGACAATTTACCTTGATAATATCTTGACGGATCTATTC
CGGAAATGTAACGTCTGACA

Downstream 100 bases:

>100_bases
AAAATAAATCCGGGAATATTCCCGGATCGACTCCTTAATTTTCCATTCCTCGATAAAAACTTTCTTTTCCCTCTGAGGAT
CCACATGTGCATAAGATAAG

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MEDPMRILFLDDEEMIRELFQEIFGVVHDLTLAGTAEEALEICKDKSFDLIITDVRLPKMSGIDFVSKLRDREINTPFIV
ITGNQDIDISIRALRLGAVDFFIKPFRMDAIRHSLQKFENLFICSQELIGKNHFQLTESKQHFSIKPSLKNLNQYVNLVM
RSISLIPGIHTDDILSIKLALYELLGNSIEHGFAGINYENKSKLLSSDVDYFDHVDRICDTLSEFVHLEVGFENQKVHVS
LKDPGTGFDPSKVPDPVTDPNASHLSGRGIFLVKMNVDELVYNDIGNEVRFSRTLKKALPTPSKVNAS

Sequences:

>Translated_308_residues
MEDPMRILFLDDEEMIRELFQEIFGVVHDLTLAGTAEEALEICKDKSFDLIITDVRLPKMSGIDFVSKLRDREINTPFIV
ITGNQDIDISIRALRLGAVDFFIKPFRMDAIRHSLQKFENLFICSQELIGKNHFQLTESKQHFSIKPSLKNLNQYVNLVM
RSISLIPGIHTDDILSIKLALYELLGNSIEHGFAGINYENKSKLLSSDVDYFDHVDRICDTLSEFVHLEVGFENQKVHVS
LKDPGTGFDPSKVPDPVTDPNASHLSGRGIFLVKMNVDELVYNDIGNEVRFSRTLKKALPTPSKVNAS
>Mature_308_residues
MEDPMRILFLDDEEMIRELFQEIFGVVHDLTLAGTAEEALEICKDKSFDLIITDVRLPKMSGIDFVSKLRDREINTPFIV
ITGNQDIDISIRALRLGAVDFFIKPFRMDAIRHSLQKFENLFICSQELIGKNHFQLTESKQHFSIKPSLKNLNQYVNLVM
RSISLIPGIHTDDILSIKLALYELLGNSIEHGFAGINYENKSKLLSSDVDYFDHVDRICDTLSEFVHLEVGFENQKVHVS
LKDPGTGFDPSKVPDPVTDPNASHLSGRGIFLVKMNVDELVYNDIGNEVRFSRTLKKALPTPSKVNAS

Specific function: Member of the two-component regulatory system dctS/dctR. Essential for expression of dctP [H]

COG id: COG4565

COG function: function code KT; Response regulator of citrate/malate metabolism

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=137, Percent_Identity=32.1167883211679, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790437, Length=116, Percent_Identity=29.3103448275862, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787487, Length=111, Percent_Identity=32.4324324324324, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788192, Length=106, Percent_Identity=33.9622641509434, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001034
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08220 HTH_DeoR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 34911; Mature: 34911

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDPMRILFLDDEEMIRELFQEIFGVVHDLTLAGTAEEALEICKDKSFDLIITDVRLPKM
CCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCC
SGIDFVSKLRDREINTPFIVITGNQDIDISIRALRLGAVDFFIKPFRMDAIRHSLQKFEN
CCHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHH
LFICSQELIGKNHFQLTESKQHFSIKPSLKNLNQYVNLVMRSISLIPGIHTDDILSIKLA
HHHCCHHHHCCCCEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LYELLGNSIEHGFAGINYENKSKLLSSDVDYFDHVDRICDTLSEFVHLEVGFENQKVHVS
HHHHHCCHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHEEEEECCCCCEEEEE
LKDPGTGFDPSKVPDPVTDPNASHLSGRGIFLVKMNVDELVYNDIGNEVRFSRTLKKALP
ECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHCCCHHHHHHHHHHHCC
TPSKVNAS
CCCCCCCC
>Mature Secondary Structure
MEDPMRILFLDDEEMIRELFQEIFGVVHDLTLAGTAEEALEICKDKSFDLIITDVRLPKM
CCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCC
SGIDFVSKLRDREINTPFIVITGNQDIDISIRALRLGAVDFFIKPFRMDAIRHSLQKFEN
CCHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHH
LFICSQELIGKNHFQLTESKQHFSIKPSLKNLNQYVNLVMRSISLIPGIHTDDILSIKLA
HHHCCHHHHCCCCEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LYELLGNSIEHGFAGINYENKSKLLSSDVDYFDHVDRICDTLSEFVHLEVGFENQKVHVS
HHHHHCCHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHEEEEECCCCCEEEEE
LKDPGTGFDPSKVPDPVTDPNASHLSGRGIFLVKMNVDELVYNDIGNEVRFSRTLKKALP
ECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHCCCHHHHHHHHHHHCC
TPSKVNAS
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9168601; 10708364 [H]