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The map label for this gene is ygcA [C]

Identifier: 116327717

GI number: 116327717

Start: 1126468

End: 1127832

Strand: Reverse

Name: ygcA [C]

Synonym: LBL_0969

Alternate gene names: 116327717

Gene position: 1127832-1126468 (Counterclockwise)

Preceding gene: 116327719

Following gene: 116327716

Centisome position: 31.2

GC content: 39.93

Gene sequence:

>1365_bases
ATGCCCGATAAAGACATAAATTTCACTCATAAAGGTACGATTGAATTTGTGAATTCCAAACTTCGTGGAGTTAGTATTGT
AAATAACACTCCGATTGAGATCCCTTATTCCCTACCCGGGGACATTTATCACGTCACTTTTTTTAAAAAGAAACGCCGTA
AGCCTTTCGCCAAACCGGAATTAATTTTTCAGACCCAAAGAACCGTATTGCCTCCTTGTCCCGCATTTACGAGATGCGGA
GGTTGTTCCGCGCAACACATTCCCTATGAAGAGCAATTCCATTACAAAACCTCGGCTCTTTTGGAAAGTTATAAAAAGGA
TTTCGGAATAGAACCTATCTTACATCCGGCCCTAAAAAAACTTCATTATAGAAATCGAATGGACTTTGCCGTATTTCCGG
GGCCGGTTATCGGACAAAGGAAATCTGGTTCCTTTAGGCATGTCGTGGATTTGGAGTTCTGTTTTATTCAAAGCGAAGAG
TCAAATGCGGAATTGAAAAGATTTCGAAGTCTAATCTCCGAATTTCCGGATCTTCCCTATAACCGAAAATCGGATTCAGG
ATTTCTAAAGTATCTGACTCTTCGAAAAGCGACAAACTCGTCCGAATTGATGACCATTCTAACTTTTATAGAAGAATTTA
AAAACTCGGATCAAGAGGAAAAACTCGCGAAAGCCTGTTTAAAATATCTGAAAGCGGACCATATCCTATTTTGTTTCAAT
CGAAAAAAAGGGGAAATTTCGGCGGTCGGAGAAGTAAAAGTTCTGAAAGGAAGAGAATCTTATCTGGAATTCGTTTCCGG
AAAAGAATTTCGAGTTCCCTTCGACTCTTTTTTTCAACCCAATCCGGAAGGATTTCAACCGATTTTGGATTTCATCGAAA
AAGAAATTCCCAAACCATCCGACCATCTCATCGATCTATTTTGCGGTTCCGGTTTTTTCAGTAGAATTTTCGCCCATAAA
TTTAGGAAAATTACGGGAATCGACTCCATCGAAAGCTCTTTAGAAATCGCCCACAAACAAATGTCTTTCGATTTTCCGGA
AATCGAATTCTCTTATCTGAGAGAAGATCTTTTTTCGAAAAAGTCCTTTTCTCAACTGAACATACTGCTTCAATCTCGGG
AAAAGAATATTTTAATCGCCGATCCTCCACGTGCCGGGCTCGGTGAATTTGTTACGGAAGCGCTGAAGAATTCAAAAATT
TCCTCTTTTTTTTACGTTTCCTGCAATCCAACCTCCCAAAAAGAAGATCTCCGGAAATTGAAGGACTTCTTTCAGATACA
AAAAATTCTCATCACGGATCCGTATCCTCAAACTCCTCACCTGGAATCCGTTGCGCTTTTGAGTTCCAAAAGTCCACCCG
TTTGA

Upstream 100 bases:

>100_bases
CTAGTAAGACTATGTTTTACCGGAAAATTTTTTATTAAAGAATCCACTTTTAAGACGAACTAAAGTTTACCACACACGCC
AAGTCGATAGACTGGTTATA

Downstream 100 bases:

>100_bases
TCCGGTAAACCTATCGACATAAGATTCCTATTTCCTCTTTCGAAGCTCGTCCCCCGCGAATGTTTTATATTATTATATTT
TTATTATATTCTTTAATGAT

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MPDKDINFTHKGTIEFVNSKLRGVSIVNNTPIEIPYSLPGDIYHVTFFKKKRRKPFAKPELIFQTQRTVLPPCPAFTRCG
GCSAQHIPYEEQFHYKTSALLESYKKDFGIEPILHPALKKLHYRNRMDFAVFPGPVIGQRKSGSFRHVVDLEFCFIQSEE
SNAELKRFRSLISEFPDLPYNRKSDSGFLKYLTLRKATNSSELMTILTFIEEFKNSDQEEKLAKACLKYLKADHILFCFN
RKKGEISAVGEVKVLKGRESYLEFVSGKEFRVPFDSFFQPNPEGFQPILDFIEKEIPKPSDHLIDLFCGSGFFSRIFAHK
FRKITGIDSIESSLEIAHKQMSFDFPEIEFSYLREDLFSKKSFSQLNILLQSREKNILIADPPRAGLGEFVTEALKNSKI
SSFFYVSCNPTSQKEDLRKLKDFFQIQKILITDPYPQTPHLESVALLSSKSPPV

Sequences:

>Translated_454_residues
MPDKDINFTHKGTIEFVNSKLRGVSIVNNTPIEIPYSLPGDIYHVTFFKKKRRKPFAKPELIFQTQRTVLPPCPAFTRCG
GCSAQHIPYEEQFHYKTSALLESYKKDFGIEPILHPALKKLHYRNRMDFAVFPGPVIGQRKSGSFRHVVDLEFCFIQSEE
SNAELKRFRSLISEFPDLPYNRKSDSGFLKYLTLRKATNSSELMTILTFIEEFKNSDQEEKLAKACLKYLKADHILFCFN
RKKGEISAVGEVKVLKGRESYLEFVSGKEFRVPFDSFFQPNPEGFQPILDFIEKEIPKPSDHLIDLFCGSGFFSRIFAHK
FRKITGIDSIESSLEIAHKQMSFDFPEIEFSYLREDLFSKKSFSQLNILLQSREKNILIADPPRAGLGEFVTEALKNSKI
SSFFYVSCNPTSQKEDLRKLKDFFQIQKILITDPYPQTPHLESVALLSSKSPPV
>Mature_453_residues
PDKDINFTHKGTIEFVNSKLRGVSIVNNTPIEIPYSLPGDIYHVTFFKKKRRKPFAKPELIFQTQRTVLPPCPAFTRCGG
CSAQHIPYEEQFHYKTSALLESYKKDFGIEPILHPALKKLHYRNRMDFAVFPGPVIGQRKSGSFRHVVDLEFCFIQSEES
NAELKRFRSLISEFPDLPYNRKSDSGFLKYLTLRKATNSSELMTILTFIEEFKNSDQEEKLAKACLKYLKADHILFCFNR
KKGEISAVGEVKVLKGRESYLEFVSGKEFRVPFDSFFQPNPEGFQPILDFIEKEIPKPSDHLIDLFCGSGFFSRIFAHKF
RKITGIDSIESSLEIAHKQMSFDFPEIEFSYLREDLFSKKSFSQLNILLQSREKNILIADPPRAGLGEFVTEALKNSKIS
SFFYVSCNPTSQKEDLRKLKDFFQIQKILITDPYPQTPHLESVALLSSKSPPV

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RNA M5U methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=372, Percent_Identity=24.4623655913978, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI51173878, Length=372, Percent_Identity=24.4623655913978, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1789148, Length=445, Percent_Identity=24.0449438202247, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1787083, Length=385, Percent_Identity=24.4155844155844, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790403, Length=195, Percent_Identity=25.1282051282051, Blast_Score=72, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24666579, Length=464, Percent_Identity=24.3534482758621, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000072
- InterPro:   IPR010280 [H]

Pfam domain/function: PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 52301; Mature: 52170

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDKDINFTHKGTIEFVNSKLRGVSIVNNTPIEIPYSLPGDIYHVTFFKKKRRKPFAKPE
CCCCCCCCCCCCHHHHHHCCCCCEEEECCCCCEEECCCCCCEEEEEEEHHHHCCCCCCCH
LIFQTQRTVLPPCPAFTRCGGCSAQHIPYEEQFHYKTSALLESYKKDFGIEPILHPALKK
HEEECCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LHYRNRMDFAVFPGPVIGQRKSGSFRHVVDLEFCFIQSEESNAELKRFRSLISEFPDLPY
HHHCCCCCEEECCCCCCCCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCC
NRKSDSGFLKYLTLRKATNSSELMTILTFIEEFKNSDQEEKLAKACLKYLKADHILFCFN
CCCCCCCHHHHEEHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEE
RKKGEISAVGEVKVLKGRESYLEFVSGKEFRVPFDSFFQPNPEGFQPILDFIEKEIPKPS
CCCCCEEECCCEEEECCHHHHHHHHCCCCEECCHHHHCCCCCCHHHHHHHHHHHHCCCCC
DHLIDLFCGSGFFSRIFAHKFRKITGIDSIESSLEIAHKQMSFDFPEIEFSYLREDLFSK
HHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
KSFSQLNILLQSREKNILIADPPRAGLGEFVTEALKNSKISSFFYVSCNPTSQKEDLRKL
HHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHH
KDFFQIQKILITDPYPQTPHLESVALLSSKSPPV
HHHHHHHHHHEECCCCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
PDKDINFTHKGTIEFVNSKLRGVSIVNNTPIEIPYSLPGDIYHVTFFKKKRRKPFAKPE
CCCCCCCCCCCHHHHHHCCCCCEEEECCCCCEEECCCCCCEEEEEEEHHHHCCCCCCCH
LIFQTQRTVLPPCPAFTRCGGCSAQHIPYEEQFHYKTSALLESYKKDFGIEPILHPALKK
HEEECCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LHYRNRMDFAVFPGPVIGQRKSGSFRHVVDLEFCFIQSEESNAELKRFRSLISEFPDLPY
HHHCCCCCEEECCCCCCCCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCC
NRKSDSGFLKYLTLRKATNSSELMTILTFIEEFKNSDQEEKLAKACLKYLKADHILFCFN
CCCCCCCHHHHEEHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEE
RKKGEISAVGEVKVLKGRESYLEFVSGKEFRVPFDSFFQPNPEGFQPILDFIEKEIPKPS
CCCCCEEECCCEEEECCHHHHHHHHCCCCEECCHHHHCCCCCCHHHHHHHHHHHHCCCCC
DHLIDLFCGSGFFSRIFAHKFRKITGIDSIESSLEIAHKQMSFDFPEIEFSYLREDLFSK
HHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
KSFSQLNILLQSREKNILIADPPRAGLGEFVTEALKNSKISSFFYVSCNPTSQKEDLRKL
HHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHH
KDFFQIQKILITDPYPQTPHLESVALLSSKSPPV
HHHHHHHHHHEECCCCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA