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The map label for this gene is frr

Identifier: 116327676

GI number: 116327676

Start: 1064817

End: 1065371

Strand: Direct

Name: frr

Synonym: LBL_0922

Alternate gene names: 116327676

Gene position: 1064817-1065371 (Clockwise)

Preceding gene: 116327675

Following gene: 116327677

Centisome position: 29.46

GC content: 41.62

Gene sequence:

>555_bases
ATGGCAAGTGAAGAAATCATTTCGGGAATGAAGACTAAAATGGATAAAACCATCGACCTGGTAAAAAAGGATTTTGGAAC
TGTTCGTACCGGACGCGCAAATCCCTCTCTTGTGGAAGATATTCGTGTGGATTATTACGGAACGTTGACTCCGATCAATC
AACTGGGAAATATTTCCGTTCCGGAACCAAGAATGCTCGTGATTTCTCCTTACGATAAGGGAATTATGAAGGATATCGAA
AAAGCGATCCAGGCTTCCGGTTTGGGTCTTCAACCGTCTAACGACGGAGTGGTAATTCGAATCATAATTCCTGAGCTGAC
GGGAGAAAGAAGAAAAGAACTTGCAAAAATCGTAAAGTCCAAATCAGAAGAAAAGAAAGTTGCGATCCGCAATATCCGTA
GGGACGCGATGGAAGATTTAAAAAAACACACCGAAGGATTGTCTCAGGACGAGATCAAAACAATTCAAGACCGGATTCAA
AAAACCACCGATTCTTATATCGATAAAATTTCCGCTCTGACCGCAGAGAAGGAAAAGGAAATCACTACGATCTAA

Upstream 100 bases:

>100_bases
ATCATTGTCTTCGATATCTTCAAACAAGGAAACCTTAAGGACTTAGTCACAGGAAAAAATATCGGGACCTTGATCTCTAA
CTCGGAGGATATTCAAATCG

Downstream 100 bases:

>100_bases
CGTGGGCTTATTCGAGTCCAAGTTTCCTCAACATATCGCCGTTATCATGGACGGTAACGGTCGATGGGCCGTTTCTCTGG
GGAAACCCCGATCGGAAGGA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MASEEIISGMKTKMDKTIDLVKKDFGTVRTGRANPSLVEDIRVDYYGTLTPINQLGNISVPEPRMLVISPYDKGIMKDIE
KAIQASGLGLQPSNDGVVIRIIIPELTGERRKELAKIVKSKSEEKKVAIRNIRRDAMEDLKKHTEGLSQDEIKTIQDRIQ
KTTDSYIDKISALTAEKEKEITTI

Sequences:

>Translated_184_residues
MASEEIISGMKTKMDKTIDLVKKDFGTVRTGRANPSLVEDIRVDYYGTLTPINQLGNISVPEPRMLVISPYDKGIMKDIE
KAIQASGLGLQPSNDGVVIRIIIPELTGERRKELAKIVKSKSEEKKVAIRNIRRDAMEDLKKHTEGLSQDEIKTIQDRIQ
KTTDSYIDKISALTAEKEKEITTI
>Mature_183_residues
ASEEIISGMKTKMDKTIDLVKKDFGTVRTGRANPSLVEDIRVDYYGTLTPINQLGNISVPEPRMLVISPYDKGIMKDIEK
AIQASGLGLQPSNDGVVIRIIIPELTGERRKELAKIVKSKSEEKKVAIRNIRRDAMEDLKKHTEGLSQDEIKTIQDRIQK
TTDSYIDKISALTAEKEKEITTI

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=171, Percent_Identity=28.6549707602339, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI291042689, Length=132, Percent_Identity=31.0606060606061, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1786368, Length=171, Percent_Identity=45.0292397660819, Blast_Score=149, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24661488, Length=177, Percent_Identity=28.2485875706215, Blast_Score=77, Evalue=8e-15,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_LEPBJ (Q04U69)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_800309.1
- ProteinModelPortal:   Q04U69
- SMR:   Q04U69
- STRING:   Q04U69
- GeneID:   4409803
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_0907
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   LBOR355277:LBJ_0907-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20641; Mature: 20510

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASEEIISGMKTKMDKTIDLVKKDFGTVRTGRANPSLVEDIRVDYYGTLTPINQLGNISV
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHHCCCCCC
PEPRMLVISPYDKGIMKDIEKAIQASGLGLQPSNDGVVIRIIIPELTGERRKELAKIVKS
CCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHC
KSEEKKVAIRNIRRDAMEDLKKHTEGLSQDEIKTIQDRIQKTTDSYIDKISALTAEKEKE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ITTI
CCCC
>Mature Secondary Structure 
ASEEIISGMKTKMDKTIDLVKKDFGTVRTGRANPSLVEDIRVDYYGTLTPINQLGNISV
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHHCCCCCC
PEPRMLVISPYDKGIMKDIEKAIQASGLGLQPSNDGVVIRIIIPELTGERRKELAKIVKS
CCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHC
KSEEKKVAIRNIRRDAMEDLKKHTEGLSQDEIKTIQDRIQKTTDSYIDKISALTAEKEKE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ITTI
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA