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The map label for this gene is sph [H]

Identifier: 116327634

GI number: 116327634

Start: 1012798

End: 1013334

Strand: Reverse

Name: sph [H]

Synonym: LBL_0869

Alternate gene names: 116327634

Gene position: 1013334-1012798 (Counterclockwise)

Preceding gene: 116327637

Following gene: 116327633

Centisome position: 28.04

GC content: 42.46

Gene sequence:

>537_bases
ATGAGAAAAGCCAAACCTCGACCCAGACCAAAACGAAAATACGACGGGGTTACTTTTGTATCCTATGCAACCGGAAAAAG
AATTCAAGCCAACAGTAAAGCTCCGAACGGATGGCTGAAAGTAGATGCTTCACGAGACACTTATTTTACCAGATTCAATT
TATATCAGGACGGCGGTGATCCCAACTGTATAGAAAGCGGTCGTATCCGAGTCGAAACCTCTGCAAATCCGAAATATTAT
TGGAATTGGTGGGCCGGCGGAGGGGGAGGTAATTACGCATACTATCCGAAATATAATGATGGTTCCAATCGACTTAGTAT
CTTAGTTATGAGTGGAGGATGTTTAGAATCCGGGGGCAAAGTCGCATTTGCGGATCATGATACTTTAGGTTATGGGTATG
ATTATTATATCACGAATTGGAAAGGAGGGAGTTGGAATGAATATCTATTCCTTTGGGTAAGGACACTTAATCCTGGTCCA
AGAGAAATTTTTACTGTTATATTAAGTCCAACACCTCCGGAAGCCGCAGCTGAATAG

Upstream 100 bases:

>100_bases
CAACTGTCTACCGGATCAACAATCGCACGAAGATAATTTACTTCTGTCTTTATTTTCCCTTCCAAATGACCAAAGTTTAG
AATTGCAACAAGATAGATCC

Downstream 100 bases:

>100_bases
CATGGTCAGCGATTGATTTGATAGGACTTTATTAGACAGACCATTGAACATAACCATGATTTACCATATGTTTTTAGAAA
TGGATTAATCATCAAAATAT

Product: sphingomyelinase C precursor

Products: NA

Alternate protein names: Sphingomyelin phosphodiesterase; SMase [H]

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MRKAKPRPRPKRKYDGVTFVSYATGKRIQANSKAPNGWLKVDASRDTYFTRFNLYQDGGDPNCIESGRIRVETSANPKYY
WNWWAGGGGGNYAYYPKYNDGSNRLSILVMSGGCLESGGKVAFADHDTLGYGYDYYITNWKGGSWNEYLFLWVRTLNPGP
REIFTVILSPTPPEAAAE

Sequences:

>Translated_178_residues
MRKAKPRPRPKRKYDGVTFVSYATGKRIQANSKAPNGWLKVDASRDTYFTRFNLYQDGGDPNCIESGRIRVETSANPKYY
WNWWAGGGGGNYAYYPKYNDGSNRLSILVMSGGCLESGGKVAFADHDTLGYGYDYYITNWKGGSWNEYLFLWVRTLNPGP
REIFTVILSPTPPEAAAE
>Mature_178_residues
MRKAKPRPRPKRKYDGVTFVSYATGKRIQANSKAPNGWLKVDASRDTYFTRFNLYQDGGDPNCIESGRIRVETSANPKYY
WNWWAGGGGGNYAYYPKYNDGSNRLSILVMSGGCLESGGKVAFADHDTLGYGYDYYITNWKGGSWNEYLFLWVRTLNPGP
REIFTVILSPTPPEAAAE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005135
- InterPro:   IPR017766 [H]

Pfam domain/function: PF03372 Exo_endo_phos [H]

EC number: =3.1.4.12 [H]

Molecular weight: Translated: 20081; Mature: 20081

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKAKPRPRPKRKYDGVTFVSYATGKRIQANSKAPNGWLKVDASRDTYFTRFNLYQDGGD
CCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCEEEEECCCCEEEEEEEEEECCCC
PNCIESGRIRVETSANPKYYWNWWAGGGGGNYAYYPKYNDGSNRLSILVMSGGCLESGGK
CCCCCCCEEEEEECCCCCEEEEEEECCCCCCCEECCCCCCCCCEEEEEEEECCCCCCCCE
VAFADHDTLGYGYDYYITNWKGGSWNEYLFLWVRTLNPGPREIFTVILSPTPPEAAAE
EEEECCCCCCCCEEEEEEECCCCCCCEEEEEEEEECCCCCCCEEEEEECCCCCHHCCC
>Mature Secondary Structure
MRKAKPRPRPKRKYDGVTFVSYATGKRIQANSKAPNGWLKVDASRDTYFTRFNLYQDGGD
CCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCEEEEECCCCEEEEEEEEEECCCC
PNCIESGRIRVETSANPKYYWNWWAGGGGGNYAYYPKYNDGSNRLSILVMSGGCLESGGK
CCCCCCCEEEEEECCCCCEEEEEEECCCCCCCEECCCCCCCCCEEEEEEEECCCCCCCCE
VAFADHDTLGYGYDYYITNWKGGSWNEYLFLWVRTLNPGPREIFTVILSPTPPEAAAE
EEEECCCCCCCCEEEEEEECCCCCCCEEEEEEEEECCCCCCCEEEEEECCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2163985 [H]