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The map label for this gene is lpxB [H]

Identifier: 116327596

GI number: 116327596

Start: 958885

End: 960081

Strand: Reverse

Name: lpxB [H]

Synonym: LBL_0828

Alternate gene names: 116327596

Gene position: 960081-958885 (Counterclockwise)

Preceding gene: 116327597

Following gene: 116327593

Centisome position: 26.56

GC content: 40.35

Gene sequence:

>1197_bases
ATGTTAGCCGGAGAACATTCCGGCGATCTTTTGGGCGGAGAATTGATTCGAGAGCTCAAAAAAAATTTTTCCGATCTGGA
AACCTTCGGAGTCGGCGGGGAAAGAATGATCGAAGAAGGTTTCGTTTCGATCGAGTCCATGGAAGAACTTTCCATCATCG
GCTTTTCCGCAATCCTTTTCAAATACAGATTCTTAAAGACTTTGATCGGAAGATTGATCGATATTGCCGTGGAGAAAAAT
TGCACTCACGCCGTTTTAATCGACTATCCTGGCTTCAATCTTCGCCTTGCAAAAGCACTCAAAAAACTAGGAATCACGGT
TGTCTTTTACGTTTCTCCCCAACTCTGGGCTTGGAAGTTCGATCGAATCTATACGATCAGAGACAATGTCGATTTGATGC
TCGTCTTATTTCCTTTCGAAAAAGAAATTTATGATAATTACGGAATTCCTTGTGAATTTGTAGGTCATCCTCTCGCGGTT
CGTTTGAGGGAAAAGATCCGTAAAGAAACGGCCATTCCCGAATTGGAAGATAAGACTCATTTTCATTTTACAATCACTTT
GATGCCCGGTTCCCGTAGTGGTGAAATTCGAAGAATCTTAAACGATCTTTTAGAAACCGCGGGACAACTTTCGGATCATT
ATGAAATTGAAAAAAAGAAGATTCGCTTTCTTTTACCGAATATTAGTCAAAAGGAAGAAGTGTATATTCTCGAACAAATA
GAATTCGCCAAATCCAAATTCCCGAATTTAAAAATCGAATATCTATTCGATCGTTCTCTCCGGGCGATCGAAGCCTCCGA
TTTGGTTTTGGTAACTTCCGGGACCGCAACATTAGAGGTGGCTTATTTCGAAAAGCCGATGGTGATCCTTTACAAAGTCA
GCATATTTACTTACTTTATCGGTTCTCTTTTTATCCGAACTCCTTACATCGGGCTTGTAAATATTCTCTCCGGAAAAGAG
ATCTGCAGGGAATTAATACAAGCAGAATGTACTCCGATGCACATCTCGGAAGAATCGATTCAACTTTTGGACAACAAAAA
ATATCGCACTAAAATGATCGAAGAAGTTCGCCAAGTAAAAGAGGCGTTAGGAATTGAAAATTCATCCAGACATGCTTCCA
GGGAAATTACGAAATTGATCAAAGGATTCTCCAAAAAAATAGGGACGAGATCCGAAAACCCGGAATTGCAAGCTTGA

Upstream 100 bases:

>100_bases
CTTACGAAAATCAACTCCACAATCCAAAAAATCCGGTAGTCGACCCATATCCAAACGCGCGTCCAGTCTGTCGGCAAAAA
AGGAAAATCCTAAAATTTTA

Downstream 100 bases:

>100_bases
ATTTAGAATTTTCTTATATTTCTAAATTGTAATCATTCCCACATTTTAAGAAACACAACAAGTAAAATTCTCAGAGAACA
AGGTGGTTATGTCGTAGCTC

Product: Lipid-A-disaccharide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MLAGEHSGDLLGGELIRELKKNFSDLETFGVGGERMIEEGFVSIESMEELSIIGFSAILFKYRFLKTLIGRLIDIAVEKN
CTHAVLIDYPGFNLRLAKALKKLGITVVFYVSPQLWAWKFDRIYTIRDNVDLMLVLFPFEKEIYDNYGIPCEFVGHPLAV
RLREKIRKETAIPELEDKTHFHFTITLMPGSRSGEIRRILNDLLETAGQLSDHYEIEKKKIRFLLPNISQKEEVYILEQI
EFAKSKFPNLKIEYLFDRSLRAIEASDLVLVTSGTATLEVAYFEKPMVILYKVSIFTYFIGSLFIRTPYIGLVNILSGKE
ICRELIQAECTPMHISEESIQLLDNKKYRTKMIEEVRQVKEALGIENSSRHASREITKLIKGFSKKIGTRSENPELQA

Sequences:

>Translated_398_residues
MLAGEHSGDLLGGELIRELKKNFSDLETFGVGGERMIEEGFVSIESMEELSIIGFSAILFKYRFLKTLIGRLIDIAVEKN
CTHAVLIDYPGFNLRLAKALKKLGITVVFYVSPQLWAWKFDRIYTIRDNVDLMLVLFPFEKEIYDNYGIPCEFVGHPLAV
RLREKIRKETAIPELEDKTHFHFTITLMPGSRSGEIRRILNDLLETAGQLSDHYEIEKKKIRFLLPNISQKEEVYILEQI
EFAKSKFPNLKIEYLFDRSLRAIEASDLVLVTSGTATLEVAYFEKPMVILYKVSIFTYFIGSLFIRTPYIGLVNILSGKE
ICRELIQAECTPMHISEESIQLLDNKKYRTKMIEEVRQVKEALGIENSSRHASREITKLIKGFSKKIGTRSENPELQA
>Mature_398_residues
MLAGEHSGDLLGGELIRELKKNFSDLETFGVGGERMIEEGFVSIESMEELSIIGFSAILFKYRFLKTLIGRLIDIAVEKN
CTHAVLIDYPGFNLRLAKALKKLGITVVFYVSPQLWAWKFDRIYTIRDNVDLMLVLFPFEKEIYDNYGIPCEFVGHPLAV
RLREKIRKETAIPELEDKTHFHFTITLMPGSRSGEIRRILNDLLETAGQLSDHYEIEKKKIRFLLPNISQKEEVYILEQI
EFAKSKFPNLKIEYLFDRSLRAIEASDLVLVTSGTATLEVAYFEKPMVILYKVSIFTYFIGSLFIRTPYIGLVNILSGKE
ICRELIQAECTPMHISEESIQLLDNKKYRTKMIEEVRQVKEALGIENSSRHASREITKLIKGFSKKIGTRSENPELQA

Specific function: Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG0763

COG function: function code M; Lipid A disaccharide synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxB family [H]

Homologues:

Organism=Escherichia coli, GI1786379, Length=387, Percent_Identity=33.8501291989664, Blast_Score=215, Evalue=4e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003835 [H]

Pfam domain/function: PF02684 LpxB [H]

EC number: =2.4.1.182 [H]

Molecular weight: Translated: 45748; Mature: 45748

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAGEHSGDLLGGELIRELKKNFSDLETFGVGGERMIEEGFVSIESMEELSIIGFSAILF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYRFLKTLIGRLIDIAVEKNCTHAVLIDYPGFNLRLAKALKKLGITVVFYVSPQLWAWKF
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCEEEEEE
DRIYTIRDNVDLMLVLFPFEKEIYDNYGIPCEFVGHPLAVRLREKIRKETAIPELEDKTH
CEEEEEECCCCEEEEEECCHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHCCCCCCCCCE
FHFTITLMPGSRSGEIRRILNDLLETAGQLSDHYEIEKKKIRFLLPNISQKEEVYILEQI
EEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCCCCEEHHHHH
EFAKSKFPNLKIEYLFDRSLRAIEASDLVLVTSGTATLEVAYFEKPMVILYKVSIFTYFI
HHHHHCCCCCEEEEEECCCHHHCCCCCEEEEECCCCEEEEEEECCCEEEEEHHHHHHHHH
GSLFIRTPYIGLVNILSGKEICRELIQAECTPMHISEESIQLLDNKKYRTKMIEEVRQVK
HHHHHHCCCHHHHHHHCHHHHHHHHHHCCCCCEEECHHHHHHHCCCHHHHHHHHHHHHHH
EALGIENSSRHASREITKLIKGFSKKIGTRSENPELQA
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLAGEHSGDLLGGELIRELKKNFSDLETFGVGGERMIEEGFVSIESMEELSIIGFSAILF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYRFLKTLIGRLIDIAVEKNCTHAVLIDYPGFNLRLAKALKKLGITVVFYVSPQLWAWKF
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCEEEEEE
DRIYTIRDNVDLMLVLFPFEKEIYDNYGIPCEFVGHPLAVRLREKIRKETAIPELEDKTH
CEEEEEECCCCEEEEEECCHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHCCCCCCCCCE
FHFTITLMPGSRSGEIRRILNDLLETAGQLSDHYEIEKKKIRFLLPNISQKEEVYILEQI
EEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCCCCEEHHHHH
EFAKSKFPNLKIEYLFDRSLRAIEASDLVLVTSGTATLEVAYFEKPMVILYKVSIFTYFI
HHHHHCCCCCEEEEEECCCHHHCCCCCEEEEECCCCEEEEEEECCCEEEEEHHHHHHHHH
GSLFIRTPYIGLVNILSGKEICRELIQAECTPMHISEESIQLLDNKKYRTKMIEEVRQVK
HHHHHHCCCHHHHHHHCHHHHHHHHHHCCCCCEEECHHHHHHHCCCHHHHHHHHHHHHHH
EALGIENSSRHASREITKLIKGFSKKIGTRSENPELQA
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA