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The map label for this gene is ykcC [H]

Identifier: 116327576

GI number: 116327576

Start: 925643

End: 926641

Strand: Reverse

Name: ykcC [H]

Synonym: LBL_0807

Alternate gene names: 116327576

Gene position: 926641-925643 (Counterclockwise)

Preceding gene: 116327581

Following gene: 116327575

Centisome position: 25.64

GC content: 42.94

Gene sequence:

>999_bases
ATGGCCGAAAGACCTCCTCTCCTTTCCGTAGTCATCCCGATCTATAACGAAGAAAAAACAATTCCCGAACTTACGAGAAG
ATTGCGTATCTTACACAATCTATTGTCATCGAAACATTCTTTTAAAAAAGACGATCTGGAAATTCTTTTCGTAAACGACG
GTTCGAGAGACGAAAGTTTTTCAGTTCTTAAAAAGTTCTGTTCGCAGACGAACGGGTATAAACTCGTAAATCTTTCTAGA
AACTACGGACACCAAACCGCTATCACCGCGGGAATAGACACCGCTGTCGGAGAAGCCGTAGTAGTAATGGACGGAGATCT
TCAAGATCCCCCCGAATTTGTAAGCGATCTATACGGAAAATTACTCGAAGGATACGATGTTGTTTACGCAAAAAGAAAAA
AAAGACCGGGAGAATCCTGGTTTAAACTTTCGACCGCACACATATTTTACAGAATCCTAAAAGAAATCACGAAATTCGAC
ATTCCGATCGATACGGGCGATTTTAGAATCATGAGTCGAAGGGTTACGGACGTTCTCTGTTCGATGAGAGAGCAACACCG
TTACATTCGAGGGCTCATTTCCTGGATCGGCTTTAAACAAATCGGACTCGAATACGAAAGAGAAGAACGTTTCGAAGGTG
TGACTAAATTCTCCCTCGGAAAGATGCTCAAATTCGCGTTAGACGGAATCACTTCCTTTTCCTCGGCTCCTCTCAAACTC
TCCTCGTATCTCGGTTTTTTTACAGCGTTCTGCGGAGCGATTTACGCGTTATACGTCGTTTATTTGAGAATTTTCACTTC
CGAAACGATCACCGGTTGGAGTTCTATGATGATCGTAGTTCTCATATTAGGCGGAACACAATTGCTTGCCCTAGGTATGA
TCGGAGAATACTTGAGCCGCGTAAACGACGAATCCAAAAATAGGCCTCTGTATGTGATCGAGGACATTTATTCTTCTGCT
TCTCAAAAACGAAGAGCGACGGCCAAGAGAAAACGCTAA

Upstream 100 bases:

>100_bases
AAAACCTATTTCGCCAATGCTGGTCGGTCCACAAGCGATTTCTTTCCTTAAAACTTTCTGGACAAAAAGCCGACTCCTGT
GATTCTTACGGGTACATATT

Downstream 100 bases:

>100_bases
TCGCTTTCCGTTTTTTCCTTCTGGAGATGAATATGAAAAAAGTTAAGAACCTACCACGTAAAAACGTAATGTCGAGCCCC
GCCGATTCTGATCTCCCAGC

Product: glycosyltransferase

Products: GDP; dolichyl D-mannosyl phosphate

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MAERPPLLSVVIPIYNEEKTIPELTRRLRILHNLLSSKHSFKKDDLEILFVNDGSRDESFSVLKKFCSQTNGYKLVNLSR
NYGHQTAITAGIDTAVGEAVVVMDGDLQDPPEFVSDLYGKLLEGYDVVYAKRKKRPGESWFKLSTAHIFYRILKEITKFD
IPIDTGDFRIMSRRVTDVLCSMREQHRYIRGLISWIGFKQIGLEYEREERFEGVTKFSLGKMLKFALDGITSFSSAPLKL
SSYLGFFTAFCGAIYALYVVYLRIFTSETITGWSSMMIVVLILGGTQLLALGMIGEYLSRVNDESKNRPLYVIEDIYSSA
SQKRRATAKRKR

Sequences:

>Translated_332_residues
MAERPPLLSVVIPIYNEEKTIPELTRRLRILHNLLSSKHSFKKDDLEILFVNDGSRDESFSVLKKFCSQTNGYKLVNLSR
NYGHQTAITAGIDTAVGEAVVVMDGDLQDPPEFVSDLYGKLLEGYDVVYAKRKKRPGESWFKLSTAHIFYRILKEITKFD
IPIDTGDFRIMSRRVTDVLCSMREQHRYIRGLISWIGFKQIGLEYEREERFEGVTKFSLGKMLKFALDGITSFSSAPLKL
SSYLGFFTAFCGAIYALYVVYLRIFTSETITGWSSMMIVVLILGGTQLLALGMIGEYLSRVNDESKNRPLYVIEDIYSSA
SQKRRATAKRKR
>Mature_331_residues
AERPPLLSVVIPIYNEEKTIPELTRRLRILHNLLSSKHSFKKDDLEILFVNDGSRDESFSVLKKFCSQTNGYKLVNLSRN
YGHQTAITAGIDTAVGEAVVVMDGDLQDPPEFVSDLYGKLLEGYDVVYAKRKKRPGESWFKLSTAHIFYRILKEITKFDI
PIDTGDFRIMSRRVTDVLCSMREQHRYIRGLISWIGFKQIGLEYEREERFEGVTKFSLGKMLKFALDGITSFSSAPLKLS
SYLGFFTAFCGAIYALYVVYLRIFTSETITGWSSMMIVVLILGGTQLLALGMIGEYLSRVNDESKNRPLYVIEDIYSSAS
QKRRATAKRKR

Specific function: Involved In O Antigen Modification. Catalyzes The Transfer Of The Glucose Residue From Udp-Glucose To A Lipid Carrier (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. GtrB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788692, Length=309, Percent_Identity=36.2459546925566, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1788588, Length=323, Percent_Identity=30.030959752322, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1787259, Length=101, Percent_Identity=30.6930693069307, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: 2.4.1.83

Molecular weight: Translated: 37919; Mature: 37788

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERPPLLSVVIPIYNEEKTIPELTRRLRILHNLLSSKHSFKKDDLEILFVNDGSRDESF
CCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHH
SVLKKFCSQTNGYKLVNLSRNYGHQTAITAGIDTAVGEAVVVMDGDLQDPPEFVSDLYGK
HHHHHHHCCCCCEEEEEECCCCCCCHHHHHCCHHHHCCEEEEECCCCCCCHHHHHHHHHH
LLEGYDVVYAKRKKRPGESWFKLSTAHIFYRILKEITKFDIPIDTGDFRIMSRRVTDVLC
HHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
SMREQHRYIRGLISWIGFKQIGLEYEREERFEGVTKFSLGKMLKFALDGITSFSSAPLKL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHH
SSYLGFFTAFCGAIYALYVVYLRIFTSETITGWSSMMIVVLILGGTQLLALGMIGEYLSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
VNDESKNRPLYVIEDIYSSASQKRRATAKRKR
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AERPPLLSVVIPIYNEEKTIPELTRRLRILHNLLSSKHSFKKDDLEILFVNDGSRDESF
CCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHH
SVLKKFCSQTNGYKLVNLSRNYGHQTAITAGIDTAVGEAVVVMDGDLQDPPEFVSDLYGK
HHHHHHHCCCCCEEEEEECCCCCCCHHHHHCCHHHHCCEEEEECCCCCCCHHHHHHHHHH
LLEGYDVVYAKRKKRPGESWFKLSTAHIFYRILKEITKFDIPIDTGDFRIMSRRVTDVLC
HHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
SMREQHRYIRGLISWIGFKQIGLEYEREERFEGVTKFSLGKMLKFALDGITSFSSAPLKL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHH
SSYLGFFTAFCGAIYALYVVYLRIFTSETITGWSSMMIVVLILGGTQLLALGMIGEYLSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
VNDESKNRPLYVIEDIYSSASQKRRATAKRKR
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDPmannose; dolichyl phosphate

Specific reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]