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The map label for this gene is yogA [H]

Identifier: 116327417

GI number: 116327417

Start: 698305

End: 699318

Strand: Reverse

Name: yogA [H]

Synonym: LBL_0626

Alternate gene names: 116327417

Gene position: 699318-698305 (Counterclockwise)

Preceding gene: 116327419

Following gene: 116327415

Centisome position: 19.35

GC content: 42.21

Gene sequence:

>1014_bases
ATGAAGGTTTATGAAATTCAAAATCAGTTCGGTCTAGAAAATTTAAAAATCTCCGAACGCCCCGATCCAATTCCAGCGCA
AGGAGAAGTGCTTGTTCGTTTTAAAGCGGTTTCTTTAAATTACAGAGATTATCTGATGGCGATCGGCAAATACAACCCGA
AACAAAAACTTCCTTTGATTCCTCTTTCCGATGGTGCGGGAGAAATTGTCCAAATCGGTCCCGGTGTCACAAAATGGAAG
GTAGGTGATAAGGTTTGTGCGAACTTTGCTCAAAGTTGGTTCGACGGAGCTCCGGAAAAGGATATGTTGAAAAATACCCT
CGGTGGACCGTTAGACGGAACTCTTTGCGAATATAGGCTTTTCGGCGAACAAGGATTGGTTCCTATGCCGGAACATCTTT
CCTTTGTGGAAGCCTCTACTCTTCCTTGCGCCGCACTGACCGCATACACGGCAATCGTAACTCACGGCAACATTCAACCC
GGAGCGACAATAGTCGTTCAGGGAACCGGAGGTGTTTCCATATTTGCATTACAATTTGCTAAAATGATGGGATGTAGAGT
AATTGCGACTTCCTCTAGCAAAGATAAACTCGACAAAGTAAAAGCCCTAGGTGCGGACGAAGTCATCAACTATAATGAAA
AAACGAATTGGGATAGGGAGGTTCGTAAAATCACGAACATGAAAGGTGCCGATCTTATCATCGAAGTAGGCGGCGCTGGT
ACTTTACAAAAATCTATTTCTAGTACGAAACCTTGGGGAACAATCGCTTTAATCGGAGTATTAGCGGGAGGAGAAAGCAA
TAACTTATCTCTATTCCCAATACTTATGCAAGGAATCAGAATTCAAGGAATCATCGTGGGAAGTAAAAGAAATTTTGAAG
ATATGAATCAGGCGATCGATGCGAATAAAATCAAACCGGTCGTGGATCACGTTTATTCTTTTGAAGAAGCTTCCAAAGCG
TTCGATACATTAAAAGCGGGAAAACATTTCGGCAAGGTTTGTATTGAAATTTAA

Upstream 100 bases:

>100_bases
TAGATTCTCTTAAAACGAAAGGAAAATACAAAGGTGAGGAAAATTCTTTCCGAAAGAATTTTGGACGAATCGATCCACAA
ACTAGGGAGAAAACGTATCC

Downstream 100 bases:

>100_bases
ACCGTAACGGTTTCAAAAGAATTCTTATCTTGTCATTACCGAAGTCCGATTATGAAGTCCAACTTCGGAGATAAGAAATT
CCGGGTGAAACTTTCACCCG

Product: Zinc-binding alcohol dehydrogenase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKVYEIQNQFGLENLKISERPDPIPAQGEVLVRFKAVSLNYRDYLMAIGKYNPKQKLPLIPLSDGAGEIVQIGPGVTKWK
VGDKVCANFAQSWFDGAPEKDMLKNTLGGPLDGTLCEYRLFGEQGLVPMPEHLSFVEASTLPCAALTAYTAIVTHGNIQP
GATIVVQGTGGVSIFALQFAKMMGCRVIATSSSKDKLDKVKALGADEVINYNEKTNWDREVRKITNMKGADLIIEVGGAG
TLQKSISSTKPWGTIALIGVLAGGESNNLSLFPILMQGIRIQGIIVGSKRNFEDMNQAIDANKIKPVVDHVYSFEEASKA
FDTLKAGKHFGKVCIEI

Sequences:

>Translated_337_residues
MKVYEIQNQFGLENLKISERPDPIPAQGEVLVRFKAVSLNYRDYLMAIGKYNPKQKLPLIPLSDGAGEIVQIGPGVTKWK
VGDKVCANFAQSWFDGAPEKDMLKNTLGGPLDGTLCEYRLFGEQGLVPMPEHLSFVEASTLPCAALTAYTAIVTHGNIQP
GATIVVQGTGGVSIFALQFAKMMGCRVIATSSSKDKLDKVKALGADEVINYNEKTNWDREVRKITNMKGADLIIEVGGAG
TLQKSISSTKPWGTIALIGVLAGGESNNLSLFPILMQGIRIQGIIVGSKRNFEDMNQAIDANKIKPVVDHVYSFEEASKA
FDTLKAGKHFGKVCIEI
>Mature_337_residues
MKVYEIQNQFGLENLKISERPDPIPAQGEVLVRFKAVSLNYRDYLMAIGKYNPKQKLPLIPLSDGAGEIVQIGPGVTKWK
VGDKVCANFAQSWFDGAPEKDMLKNTLGGPLDGTLCEYRLFGEQGLVPMPEHLSFVEASTLPCAALTAYTAIVTHGNIQP
GATIVVQGTGGVSIFALQFAKMMGCRVIATSSSKDKLDKVKALGADEVINYNEKTNWDREVRKITNMKGADLIIEVGGAG
TLQKSISSTKPWGTIALIGVLAGGESNNLSLFPILMQGIRIQGIIVGSKRNFEDMNQAIDANKIKPVVDHVYSFEEASKA
FDTLKAGKHFGKVCIEI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=343, Percent_Identity=27.4052478134111, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI22538444, Length=343, Percent_Identity=27.4052478134111, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI194239674, Length=325, Percent_Identity=27.0769230769231, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI13236495, Length=325, Percent_Identity=27.0769230769231, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI18379349, Length=337, Percent_Identity=25.2225519287834, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI34577061, Length=362, Percent_Identity=28.7292817679558, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI71565152, Length=354, Percent_Identity=27.1186440677966, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI4501933, Length=367, Percent_Identity=27.5204359673025, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4501929, Length=363, Percent_Identity=27.5482093663912, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI156627571, Length=339, Percent_Identity=25.6637168141593, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI194239676, Length=323, Percent_Identity=26.625386996904, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI47519420, Length=348, Percent_Identity=26.1494252873563, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI28557745, Length=252, Percent_Identity=28.1746031746032, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI41872631, Length=325, Percent_Identity=24.6153846153846, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI71565154, Length=354, Percent_Identity=25.9887005649718, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI71743840, Length=368, Percent_Identity=24.1847826086957, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI262073058, Length=368, Percent_Identity=24.1847826086957, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI156523966, Length=353, Percent_Identity=22.6628895184136, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4501939, Length=353, Percent_Identity=22.6628895184136, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1788073, Length=328, Percent_Identity=24.0853658536585, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87082125, Length=348, Percent_Identity=25.8620689655172, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790485, Length=333, Percent_Identity=24.3243243243243, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788075, Length=337, Percent_Identity=24.9258160237389, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786552, Length=222, Percent_Identity=25.2252252252252, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081918, Length=325, Percent_Identity=24, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790045, Length=343, Percent_Identity=21.865889212828, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789651, Length=263, Percent_Identity=27.3764258555133, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71988145, Length=334, Percent_Identity=24.5508982035928, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17562584, Length=333, Percent_Identity=24.6246246246246, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17507255, Length=315, Percent_Identity=26.031746031746, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17562582, Length=323, Percent_Identity=25.077399380805, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17562876, Length=269, Percent_Identity=26.7657992565056, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI212642053, Length=225, Percent_Identity=25.3333333333333, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562878, Length=216, Percent_Identity=25, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17565904, Length=319, Percent_Identity=22.5705329153605, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319621, Length=349, Percent_Identity=26.9340974212034, Blast_Score=99, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6323961, Length=317, Percent_Identity=28.0757097791798, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6323729, Length=335, Percent_Identity=23.5820895522388, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319955, Length=333, Percent_Identity=26.1261261261261, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322619, Length=333, Percent_Identity=26.1261261261261, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324486, Length=299, Percent_Identity=26.4214046822742, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6323099, Length=340, Percent_Identity=26.4705882352941, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319520, Length=341, Percent_Identity=24.633431085044, Blast_Score=73, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6320033, Length=352, Percent_Identity=23.8636363636364, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581341, Length=379, Percent_Identity=23.4828496042216, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24581339, Length=379, Percent_Identity=23.4828496042216, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24581345, Length=336, Percent_Identity=26.7857142857143, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19920632, Length=224, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI221330659, Length=224, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI17737897, Length=340, Percent_Identity=24.7058823529412, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17137530, Length=340, Percent_Identity=23.8235294117647, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI17737895, Length=362, Percent_Identity=22.0994475138122, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 36549; Mature: 36549

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVYEIQNQFGLENLKISERPDPIPAQGEVLVRFKAVSLNYRDYLMAIGKYNPKQKLPLI
CCEEEECHHCCCCCCEECCCCCCCCCCCCEEEEEEEEEECHHHHHHHHCCCCCCCCCCEE
PLSDGAGEIVQIGPGVTKWKVGDKVCANFAQSWFDGAPEKDMLKNTLGGPLDGTLCEYRL
ECCCCCCCEEEECCCCEEEECCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCEEEEEE
FGEQGLVPMPEHLSFVEASTLPCAALTAYTAIVTHGNIQPGATIVVQGTGGVSIFALQFA
ECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHEECCCCCCCCEEEEECCCCCCHHHHHHH
KMMGCRVIATSSSKDKLDKVKALGADEVINYNEKTNWDREVRKITNMKGADLIIEVGGAG
HHHCCEEEEECCCHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCC
TLQKSISSTKPWGTIALIGVLAGGESNNLSLFPILMQGIRIQGIIVGSKRNFEDMNQAID
HHHHHHHCCCCCCCEEEEEEEECCCCCCEEEHHHHHCCEEEEEEEEECCCCHHHHHHHHC
ANKIKPVVDHVYSFEEASKAFDTLKAGKHFGKVCIEI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEC
>Mature Secondary Structure
MKVYEIQNQFGLENLKISERPDPIPAQGEVLVRFKAVSLNYRDYLMAIGKYNPKQKLPLI
CCEEEECHHCCCCCCEECCCCCCCCCCCCEEEEEEEEEECHHHHHHHHCCCCCCCCCCEE
PLSDGAGEIVQIGPGVTKWKVGDKVCANFAQSWFDGAPEKDMLKNTLGGPLDGTLCEYRL
ECCCCCCCEEEECCCCEEEECCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCEEEEEE
FGEQGLVPMPEHLSFVEASTLPCAALTAYTAIVTHGNIQPGATIVVQGTGGVSIFALQFA
ECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHEECCCCCCCCEEEEECCCCCCHHHHHHH
KMMGCRVIATSSSKDKLDKVKALGADEVINYNEKTNWDREVRKITNMKGADLIIEVGGAG
HHHCCEEEEECCCHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCC
TLQKSISSTKPWGTIALIGVLAGGESNNLSLFPILMQGIRIQGIIVGSKRNFEDMNQAID
HHHHHHHCCCCCCCEEEEEEEECCCCCCEEEHHHHHCCEEEEEEEEECCCCHHHHHHHHC
ANKIKPVVDHVYSFEEASKAFDTLKAGKHFGKVCIEI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]