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The map label for this gene is yogA [H]

Identifier: 116327313

GI number: 116327313

Start: 554219

End: 555466

Strand: Reverse

Name: yogA [H]

Synonym: LBL_0505

Alternate gene names: 116327313

Gene position: 555466-554219 (Counterclockwise)

Preceding gene: 116327315

Following gene: 116327312

Centisome position: 15.37

GC content: 49.28

Gene sequence:

>1248_bases
ATGAGCCAAATTGAATCCGTTCCAGTTGGAACCCTTCCCCCCTTGGGCCAGGTTCCTAAAAAAATGTATGCACAGGTCGT
TAGAGCCGATCGTTTCGGCGACCCAATCAAAGCAATTCAGGAAGAACTCATCGATGTTCCAGAAATAGCTCCGAACGAAG
TACTCGTCGCGGTCATGGCAGCCGGTGTAAATTATAATAACGTTTGGGCCGCCCTTGGATTTCCCGTAGACGTAATCGGC
GCCAGAAACAAAAAAGGCGAACCCGAACCGTTTCATATCGGCGGGTCCGACGCATCCGGAATCGTATATAAAGTCGGTTC
CGATGTTAAGAACGTAAAAGTAGGAGACGAAGTCGTTCTTCACTGCGGAATCTGGGATCGCAACGATCCTTGGGTCAAAG
CGGGAAAAGATCCGATGTTCGCTCCTTCTCAGTTGATCTGGGGATACGAAACGAACTGGGGATCCTTTGCACAGTTTTGC
AAGGTTCAAGATCACCAATGTCTTCCAAAACCGAAACATCTCTCCTGGGAAGAAGCCGCCGCCTATATGCTCGTAGGAGC
GACCGCATATAGAATGCTTCACCACTGGAAACCGAACGACGTACAAAAAGACGACGTAGTTCTGATTTGGGGAGGCGCAG
GTGGGCTCGGAGCAATGGCGATTCAGATTGTAAAAGCGGCAGGCGGAGTTCCAATCGCGGTCGTTTCCGAAGACGATAAG
TTCGACTTCTGTATGAAGTTAGGCGCGGCGGGTGTTATCAACCGTAAGAAATTCTCTCATTGGGGCGCTTTAACTTCCGA
AATCAACAAGATGGAAAAATTTGCGGAATGGACAAAGTCCGCTCGCGAATTCGGAAAAGCGATTTGGGACATCGCAGGAA
AAGGAAAAAATCCGAAGATCGTCTTCGAACATCCGGGCGAAACCACGATTCCTACTTCCATGTTCGTGTGCGAAACAGGT
GGCATGGTCGTAATCTGTGCGGGAACTACGGGCTATAACGCAACGGTCGACTTGCGCTATCTCTGGATGAGACAAAAACG
TCTCCAAGGCTCGCACTTTGCGAACGACGACAACTCGAAAGGCCTGAACGACTTAGTGATCGATAAAAAAGTCGATCCTT
GTCTTTCCAAAACCTTCACTTGGAACGAGACCGCGCATGCACACCAATTGATGAAAGAAAACAAACATCCGGCCGGAAAC
ATGTCGATCTTGGTCGGAGCCGACAAACTGGGACTCGGAAGAAAATAA

Upstream 100 bases:

>100_bases
TTCTTTTAGGAATCAAAAGTATCCAAACTTCCCTCAAAAACGTAGAAAATCCCATTAAAATTGGTGTAGATCAAATACCG
AAGCTCGGAAATCTGTGCAC

Downstream 100 bases:

>100_bases
TTTCACGATCCTAATCAACTCGGATTAACAAAAACCCCGAAAGCAACCGGCTCCTAGGGGTTTTATTTTTAAATGGAAAT
TTATCCTAAAGAAAACTCAA

Product: Zinc-binding dehydrogenase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MSQIESVPVGTLPPLGQVPKKMYAQVVRADRFGDPIKAIQEELIDVPEIAPNEVLVAVMAAGVNYNNVWAALGFPVDVIG
ARNKKGEPEPFHIGGSDASGIVYKVGSDVKNVKVGDEVVLHCGIWDRNDPWVKAGKDPMFAPSQLIWGYETNWGSFAQFC
KVQDHQCLPKPKHLSWEEAAAYMLVGATAYRMLHHWKPNDVQKDDVVLIWGGAGGLGAMAIQIVKAAGGVPIAVVSEDDK
FDFCMKLGAAGVINRKKFSHWGALTSEINKMEKFAEWTKSAREFGKAIWDIAGKGKNPKIVFEHPGETTIPTSMFVCETG
GMVVICAGTTGYNATVDLRYLWMRQKRLQGSHFANDDNSKGLNDLVIDKKVDPCLSKTFTWNETAHAHQLMKENKHPAGN
MSILVGADKLGLGRK

Sequences:

>Translated_415_residues
MSQIESVPVGTLPPLGQVPKKMYAQVVRADRFGDPIKAIQEELIDVPEIAPNEVLVAVMAAGVNYNNVWAALGFPVDVIG
ARNKKGEPEPFHIGGSDASGIVYKVGSDVKNVKVGDEVVLHCGIWDRNDPWVKAGKDPMFAPSQLIWGYETNWGSFAQFC
KVQDHQCLPKPKHLSWEEAAAYMLVGATAYRMLHHWKPNDVQKDDVVLIWGGAGGLGAMAIQIVKAAGGVPIAVVSEDDK
FDFCMKLGAAGVINRKKFSHWGALTSEINKMEKFAEWTKSAREFGKAIWDIAGKGKNPKIVFEHPGETTIPTSMFVCETG
GMVVICAGTTGYNATVDLRYLWMRQKRLQGSHFANDDNSKGLNDLVIDKKVDPCLSKTFTWNETAHAHQLMKENKHPAGN
MSILVGADKLGLGRK
>Mature_414_residues
SQIESVPVGTLPPLGQVPKKMYAQVVRADRFGDPIKAIQEELIDVPEIAPNEVLVAVMAAGVNYNNVWAALGFPVDVIGA
RNKKGEPEPFHIGGSDASGIVYKVGSDVKNVKVGDEVVLHCGIWDRNDPWVKAGKDPMFAPSQLIWGYETNWGSFAQFCK
VQDHQCLPKPKHLSWEEAAAYMLVGATAYRMLHHWKPNDVQKDDVVLIWGGAGGLGAMAIQIVKAAGGVPIAVVSEDDKF
DFCMKLGAAGVINRKKFSHWGALTSEINKMEKFAEWTKSAREFGKAIWDIAGKGKNPKIVFEHPGETTIPTSMFVCETGG
MVVICAGTTGYNATVDLRYLWMRQKRLQGSHFANDDNSKGLNDLVIDKKVDPCLSKTFTWNETAHAHQLMKENKHPAGNM
SILVGADKLGLGRK

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI47519420, Length=234, Percent_Identity=30.3418803418803, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1790485, Length=369, Percent_Identity=24.9322493224932, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71988145, Length=318, Percent_Identity=26.7295597484277, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562876, Length=291, Percent_Identity=26.4604810996564, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323729, Length=237, Percent_Identity=29.957805907173, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 45454; Mature: 45323

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQIESVPVGTLPPLGQVPKKMYAQVVRADRFGDPIKAIQEELIDVPEIAPNEVLVAVMA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHH
AGVNYNNVWAALGFPVDVIGARNKKGEPEPFHIGGSDASGIVYKVGSDVKNVKVGDEVVL
CCCCCCCEEEECCCCEEEEECCCCCCCCCCEEECCCCCCCEEEEECCCCCCEECCCEEEE
HCGIWDRNDPWVKAGKDPMFAPSQLIWGYETNWGSFAQFCKVQDHQCLPKPKHLSWEEAA
EECCCCCCCCCEECCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCHHHHH
AYMLVGATAYRMLHHWKPNDVQKDDVVLIWGGAGGLGAMAIQIVKAAGGVPIAVVSEDDK
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCC
FDFCMKLGAAGVINRKKFSHWGALTSEINKMEKFAEWTKSAREFGKAIWDIAGKGKNPKI
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VFEHPGETTIPTSMFVCETGGMVVICAGTTGYNATVDLRYLWMRQKRLQGSHFANDDNSK
EEECCCCCCCCCEEEEEECCCEEEEEECCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCC
GLNDLVIDKKVDPCLSKTFTWNETAHAHQLMKENKHPAGNMSILVGADKLGLGRK
CCCCEEECCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure 
SQIESVPVGTLPPLGQVPKKMYAQVVRADRFGDPIKAIQEELIDVPEIAPNEVLVAVMA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHH
AGVNYNNVWAALGFPVDVIGARNKKGEPEPFHIGGSDASGIVYKVGSDVKNVKVGDEVVL
CCCCCCCEEEECCCCEEEEECCCCCCCCCCEEECCCCCCCEEEEECCCCCCEECCCEEEE
HCGIWDRNDPWVKAGKDPMFAPSQLIWGYETNWGSFAQFCKVQDHQCLPKPKHLSWEEAA
EECCCCCCCCCEECCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCHHHHH
AYMLVGATAYRMLHHWKPNDVQKDDVVLIWGGAGGLGAMAIQIVKAAGGVPIAVVSEDDK
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCC
FDFCMKLGAAGVINRKKFSHWGALTSEINKMEKFAEWTKSAREFGKAIWDIAGKGKNPKI
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VFEHPGETTIPTSMFVCETGGMVVICAGTTGYNATVDLRYLWMRQKRLQGSHFANDDNSK
EEECCCCCCCCCEEEEEECCCEEEEEECCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCC
GLNDLVIDKKVDPCLSKTFTWNETAHAHQLMKENKHPAGNMSILVGADKLGLGRK
CCCCEEECCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]