| Definition | Leptospira borgpetersenii serovar Hardjo-bovis L550 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008508 |
| Length | 3,614,446 |
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The map label for this gene is mrcA [H]
Identifier: 116327306
GI number: 116327306
Start: 546269
End: 549007
Strand: Reverse
Name: mrcA [H]
Synonym: LBL_0498
Alternate gene names: 116327306
Gene position: 549007-546269 (Counterclockwise)
Preceding gene: 116327307
Following gene: 116327305
Centisome position: 15.19
GC content: 43.99
Gene sequence:
>2739_bases ATGGAAACGGGAATTCAAACTCTTAGAAGTTCTCGATTTTTGTGTCCCGAATGTGAAACGACTTCCCGTTTGCCGGAAGG AGTTCCTACAGGTTCGATTTTTAGATTAACCTGCTACCAATGCGGTCACAAGGCTCTCGTGAAAATGGAAGTTCCGACTC ATATAAAGTCGATTTTCCCCTCCGACGAAATTCTACCTCATCCGGAACAACCCAAAGATGTAGGAACTCCCCACTTTCAA GCTCCTTCTCATACAGGTTTTGAATCTACCGGCCCAGGAATCCCAGAAAAAATTTGGGGCTTTGTTTCTCAATTTCAGAT CCACCTGAACGAGAAAATACGGAAACTGATACAAAAATTCCGGAATATACCAAAAGGCCAAAAGTCGGATCCTTTTTCAT CAACGACGGACAAACCCTTCCTTCAAAGGAAAAAGATTCCATTCGAAAAAAAACCGTTTTTTATAGTTCGACGTGAGATC GAAGACAATGGACAACCCCGGATCAAAACTCTCGCCGAGAGACTGAGAGAACAAATCGGCGATCGTCGTTTCCAACTTCC GAATGTGGTCTTACTTTCCGCGGGTGTGATCATTTCTTTGCTTCTTGTCGGGATGATACTTTTCTGGGTGGGAGTGATCA CTCGAGAATCGGAACTTAAGGAAATGATTTCGCTTTTTTACAATCATCAGCCCTCTGTGATCTACGATCGGGACGGGAAA AAGGTTTCTGAAATTTTCGCGAAAAAAACGAGTAATCTAGAATGGGACGCTTATCCTGAAAACCTGAAAAAAATCGTTCT TTTGGTAGAAGACCGAAAGTTTTTTTCTCATAGTGGAATTAACTACATGTCCGTTCTACGTGCAGCTTTCGTGAACATCG CGAGTTTCCGTTTTAAACAAGGAGCGTCTACGATTACCCAGCAACTTGCAAGAATTTTACTGGACGATCGCGAAAAAAGT CTCGTCCGAAAGATCAAGGAGGCCCAGCTTGCTTTTGCTCTAGAATATACATATGAGAAAAAGCAAATATTATTATATTA TCTAAATAACGTATATCTGGGCCACGGAGCGTTCGGATTTGCAAGCGCAGCCGAATTCTATTTCAGAAAGACCCCTTCCG AGCTCAACACGGAGGAGATGATCGTTCTCGCTTCGTTGGCTTCGGCTCCGAATCGTTTTTCACCTTTGAAAAATCCGGAT CTATCCAGACAACGCGTAAACGCGATCGTCCATTCTTTTCAAAAACAAGAAATTTTAAAAGAAAATCCGAAACCGAAACT GGACGAGATCTATCTTGCATTTCACATGAGATCACCGGGCGAGACAGTGTTCGGAAACCGTAAGGATGATTCTCCTTATG TGACGGAACACGTTCGTAAATTTTTGAATTCCCTATACCCAGATTCCAATATCTACGAAACCGGCGGTTTTTCAATTCAC ACCACGATTGCGGAACCGGTTCAAGCCGAACTCTCGAAGATTGTAAAGAATTATCTAGACAACATTCAAAAGAGCGGGCT CGTTCGCAAAACAAAACTCACGGATAACAAAAATTCCAGCGAGACCGCGGTTTTTCGAAAATACGTTCAGGATATTTCAC CGGCGCTCGAACTTTTCATTGATACGGACTCTTTCGGCGGAAAAAGCGAATCCGGCCTACAAGTTGCGTTAGTCGCTGTT GACCCTGCCACGGGAGAAATCCTATTGATGCACGGTGGTTCGGAATTCAAAGCCGACAATCAATTGGACAGAACTACCGC GATGAAACGTCAGACGGGTTCTTCCATTAAACCAATTTTATATTCCGCCGCGATCGAGACCGAACTCATCAGCGCCTCTT CCAGAATTTTGGACGCCCCTTTGATTTATAGAAATCAAACCGGAAATTGGATGCCGGAAAATATAGGAAATCAATACGAC GGAGATATTAGCGTTAGACATGCTTTAGCAAAGTCCAAAAATACGGCGGCAGTTCAGATCGCGGAAAAGTTAGGAATTTC AAAAATTCAAGACTTTTTTCAAAAGTATTTCTTCCCTGATCCGAAAGTACTTCAGTCTAGATTTAGAGGGGACCTTTCCC TTGCACTCGGTTCTTTGGAAATTTCTCCTCTGGAAATGGCGCTTGCGTATTCCGCGTTTGCAAACGACGGAACAATCAAA CGTCCTTATTTGATTCAAAAAATCACGGATCGATCCGGCAAGATCGTCTACGAAAGAAAATCCACAGACGAATTCGGATT AAAAGTTCCGGAAGAAAGAAAGGTGTTGTCTTCCCAAGTCGCGGAAATCATGATCGACCTTCTTCACGGAAGCGCAAATT CGGCGGGAGTGAGAAGCACCGGATATAGAGGGGAAGTTGCCGGCAAAACGGGGACTACAAATGATAACAGAGACAACTGG TTCGTGGGAGTAAAACCGGGAATGTCAATGGCAATTTGGCTCGGTTACGACGACCCGAGTTACGGACTCGGATCATCCGC GTTAGGTGGCACTGTTGCAGCTCCTCTTTGGGGATCCGTCGCAAAAACTTTCGAAGCCACGGAAGACGAAAAAAGAAAAT ATCCGGTTACCGAACACGCGATAAGCATAACCGTTTGCGAAGAATCAGGCAAACTTCCCGGACCTTTCTGTAAACATCCC CGAAAAGAACTTTTCAAAAATGGAACCGTACCCTCCGAAATTTGCCCTTTAAATCACGGAACAGACGTAAAGCGGGAAGT TCTCAGAAATGTATTTTAA
Upstream 100 bases:
>100_bases ACTCAAGGGTTGCGATTTTACCGTGATTACGGAAAGGGGAAAAAAAGAGAATTAAAATACTTGTCTGGAACTCTAGGATT CTCCGACAATTAAGGGGATA
Downstream 100 bases:
>100_bases ATTTTTTTATTTCATTATAATATTATTATATTCTTTCTCAAGTGCACATCCCGTTTCCTACGAAGAGGCGTACACAATGG AAAAAGAGGATCCACTGTTT
Product: membrane carboxypeptidase/penicillin-binding protein
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 912; Mature: 912
Protein sequence:
>912_residues METGIQTLRSSRFLCPECETTSRLPEGVPTGSIFRLTCYQCGHKALVKMEVPTHIKSIFPSDEILPHPEQPKDVGTPHFQ APSHTGFESTGPGIPEKIWGFVSQFQIHLNEKIRKLIQKFRNIPKGQKSDPFSSTTDKPFLQRKKIPFEKKPFFIVRREI EDNGQPRIKTLAERLREQIGDRRFQLPNVVLLSAGVIISLLLVGMILFWVGVITRESELKEMISLFYNHQPSVIYDRDGK KVSEIFAKKTSNLEWDAYPENLKKIVLLVEDRKFFSHSGINYMSVLRAAFVNIASFRFKQGASTITQQLARILLDDREKS LVRKIKEAQLAFALEYTYEKKQILLYYLNNVYLGHGAFGFASAAEFYFRKTPSELNTEEMIVLASLASAPNRFSPLKNPD LSRQRVNAIVHSFQKQEILKENPKPKLDEIYLAFHMRSPGETVFGNRKDDSPYVTEHVRKFLNSLYPDSNIYETGGFSIH TTIAEPVQAELSKIVKNYLDNIQKSGLVRKTKLTDNKNSSETAVFRKYVQDISPALELFIDTDSFGGKSESGLQVALVAV DPATGEILLMHGGSEFKADNQLDRTTAMKRQTGSSIKPILYSAAIETELISASSRILDAPLIYRNQTGNWMPENIGNQYD GDISVRHALAKSKNTAAVQIAEKLGISKIQDFFQKYFFPDPKVLQSRFRGDLSLALGSLEISPLEMALAYSAFANDGTIK RPYLIQKITDRSGKIVYERKSTDEFGLKVPEERKVLSSQVAEIMIDLLHGSANSAGVRSTGYRGEVAGKTGTTNDNRDNW FVGVKPGMSMAIWLGYDDPSYGLGSSALGGTVAAPLWGSVAKTFEATEDEKRKYPVTEHAISITVCEESGKLPGPFCKHP RKELFKNGTVPSEICPLNHGTDVKREVLRNVF
Sequences:
>Translated_912_residues METGIQTLRSSRFLCPECETTSRLPEGVPTGSIFRLTCYQCGHKALVKMEVPTHIKSIFPSDEILPHPEQPKDVGTPHFQ APSHTGFESTGPGIPEKIWGFVSQFQIHLNEKIRKLIQKFRNIPKGQKSDPFSSTTDKPFLQRKKIPFEKKPFFIVRREI EDNGQPRIKTLAERLREQIGDRRFQLPNVVLLSAGVIISLLLVGMILFWVGVITRESELKEMISLFYNHQPSVIYDRDGK KVSEIFAKKTSNLEWDAYPENLKKIVLLVEDRKFFSHSGINYMSVLRAAFVNIASFRFKQGASTITQQLARILLDDREKS LVRKIKEAQLAFALEYTYEKKQILLYYLNNVYLGHGAFGFASAAEFYFRKTPSELNTEEMIVLASLASAPNRFSPLKNPD LSRQRVNAIVHSFQKQEILKENPKPKLDEIYLAFHMRSPGETVFGNRKDDSPYVTEHVRKFLNSLYPDSNIYETGGFSIH TTIAEPVQAELSKIVKNYLDNIQKSGLVRKTKLTDNKNSSETAVFRKYVQDISPALELFIDTDSFGGKSESGLQVALVAV DPATGEILLMHGGSEFKADNQLDRTTAMKRQTGSSIKPILYSAAIETELISASSRILDAPLIYRNQTGNWMPENIGNQYD GDISVRHALAKSKNTAAVQIAEKLGISKIQDFFQKYFFPDPKVLQSRFRGDLSLALGSLEISPLEMALAYSAFANDGTIK RPYLIQKITDRSGKIVYERKSTDEFGLKVPEERKVLSSQVAEIMIDLLHGSANSAGVRSTGYRGEVAGKTGTTNDNRDNW FVGVKPGMSMAIWLGYDDPSYGLGSSALGGTVAAPLWGSVAKTFEATEDEKRKYPVTEHAISITVCEESGKLPGPFCKHP RKELFKNGTVPSEICPLNHGTDVKREVLRNVF >Mature_912_residues METGIQTLRSSRFLCPECETTSRLPEGVPTGSIFRLTCYQCGHKALVKMEVPTHIKSIFPSDEILPHPEQPKDVGTPHFQ APSHTGFESTGPGIPEKIWGFVSQFQIHLNEKIRKLIQKFRNIPKGQKSDPFSSTTDKPFLQRKKIPFEKKPFFIVRREI EDNGQPRIKTLAERLREQIGDRRFQLPNVVLLSAGVIISLLLVGMILFWVGVITRESELKEMISLFYNHQPSVIYDRDGK KVSEIFAKKTSNLEWDAYPENLKKIVLLVEDRKFFSHSGINYMSVLRAAFVNIASFRFKQGASTITQQLARILLDDREKS LVRKIKEAQLAFALEYTYEKKQILLYYLNNVYLGHGAFGFASAAEFYFRKTPSELNTEEMIVLASLASAPNRFSPLKNPD LSRQRVNAIVHSFQKQEILKENPKPKLDEIYLAFHMRSPGETVFGNRKDDSPYVTEHVRKFLNSLYPDSNIYETGGFSIH TTIAEPVQAELSKIVKNYLDNIQKSGLVRKTKLTDNKNSSETAVFRKYVQDISPALELFIDTDSFGGKSESGLQVALVAV DPATGEILLMHGGSEFKADNQLDRTTAMKRQTGSSIKPILYSAAIETELISASSRILDAPLIYRNQTGNWMPENIGNQYD GDISVRHALAKSKNTAAVQIAEKLGISKIQDFFQKYFFPDPKVLQSRFRGDLSLALGSLEISPLEMALAYSAFANDGTIK RPYLIQKITDRSGKIVYERKSTDEFGLKVPEERKVLSSQVAEIMIDLLHGSANSAGVRSTGYRGEVAGKTGTTNDNRDNW FVGVKPGMSMAIWLGYDDPSYGLGSSALGGTVAAPLWGSVAKTFEATEDEKRKYPVTEHAISITVCEESGKLPGPFCKHP RKELFKNGTVPSEICPLNHGTDVKREVLRNVF
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786343, Length=575, Percent_Identity=26.7826086956522, Blast_Score=186, Evalue=7e-48, Organism=Escherichia coli, GI87082258, Length=269, Percent_Identity=35.3159851301115, Blast_Score=150, Evalue=3e-37, Organism=Escherichia coli, GI1788867, Length=180, Percent_Identity=35, Blast_Score=99, Evalue=1e-21, Organism=Escherichia coli, GI1789601, Length=128, Percent_Identity=39.84375, Blast_Score=80, Evalue=8e-16,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 3.4.-.-
Molecular weight: Translated: 102401; Mature: 102401
Theoretical pI: Translated: 9.43; Mature: 9.43
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure METGIQTLRSSRFLCPECETTSRLPEGVPTGSIFRLTCYQCGHKALVKMEVPTHIKSIFP CCHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCEEEEHHHHCCCCEEEEEECCHHHHHHCC SDEILPHPEQPKDVGTPHFQAPSHTGFESTGPGIPEKIWGFVSQFQIHLNEKIRKLIQKF CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH RNIPKGQKSDPFSSTTDKPFLQRKKIPFEKKPFFIVRREIEDNGQPRIKTLAERLREQIG HCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHC DRRFQLPNVVLLSAGVIISLLLVGMILFWVGVITRESELKEMISLFYNHQPSVIYDRDGK CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEECCCCH KVSEIFAKKTSNLEWDAYPENLKKIVLLVEDRKFFSHSGINYMSVLRAAFVNIASFRFKQ HHHHHHHHHCCCCCCCCCHHCCEEEEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHC GASTITQQLARILLDDREKSLVRKIKEAQLAFALEYTYEKKQILLYYLNNVYLGHGAFGF CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEHHCCHHEEEEEECCEEECCCCHHH ASAAEFYFRKTPSELNTEEMIVLASLASAPNRFSPLKNPDLSRQRVNAIVHSFQKQEILK HHHHHHHHHCCCCCCCHHHEEHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH ENPKPKLDEIYLAFHMRSPGETVFGNRKDDSPYVTEHVRKFLNSLYPDSNIYETGGFSIH CCCCCCHHEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCEEEE TTIAEPVQAELSKIVKNYLDNIQKSGLVRKTKLTDNKNSSETAVFRKYVQDISPALELFI EHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHEEEE DTDSFGGKSESGLQVALVAVDPATGEILLMHGGSEFKADNQLDRTTAMKRQTGSSIKPIL CCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHH YSAAIETELISASSRILDAPLIYRNQTGNWMPENIGNQYDGDISVRHALAKSKNTAAVQI HHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHCCCCCCCCHHHHHHHHHCCCCHHHHH AEKLGISKIQDFFQKYFFPDPKVLQSRFRGDLSLALGSLEISPLEMALAYSAFANDGTIK HHHHCHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCC RPYLIQKITDRSGKIVYERKSTDEFGLKVPEERKVLSSQVAEIMIDLLHGSANSAGVRST CCHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC GYRGEVAGKTGTTNDNRDNWFVGVKPGMSMAIWLGYDDPSYGLGSSALGGTVAAPLWGSV CCCCEECCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHH AKTFEATEDEKRKYPVTEHAISITVCEESGKLPGPFCKHPRKELFKNGTVPSEICPLNHG HHHHHCCCHHHHCCCCCHHEEEEEEECCCCCCCCHHHCCCHHHHHHCCCCCHHHCCCCCC TDVKREVLRNVF CHHHHHHHHHCC >Mature Secondary Structure METGIQTLRSSRFLCPECETTSRLPEGVPTGSIFRLTCYQCGHKALVKMEVPTHIKSIFP CCHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCEEEEHHHHCCCCEEEEEECCHHHHHHCC SDEILPHPEQPKDVGTPHFQAPSHTGFESTGPGIPEKIWGFVSQFQIHLNEKIRKLIQKF CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH RNIPKGQKSDPFSSTTDKPFLQRKKIPFEKKPFFIVRREIEDNGQPRIKTLAERLREQIG HCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHC DRRFQLPNVVLLSAGVIISLLLVGMILFWVGVITRESELKEMISLFYNHQPSVIYDRDGK CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEECCCCH KVSEIFAKKTSNLEWDAYPENLKKIVLLVEDRKFFSHSGINYMSVLRAAFVNIASFRFKQ HHHHHHHHHCCCCCCCCCHHCCEEEEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHC GASTITQQLARILLDDREKSLVRKIKEAQLAFALEYTYEKKQILLYYLNNVYLGHGAFGF CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEHHCCHHEEEEEECCEEECCCCHHH ASAAEFYFRKTPSELNTEEMIVLASLASAPNRFSPLKNPDLSRQRVNAIVHSFQKQEILK HHHHHHHHHCCCCCCCHHHEEHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH ENPKPKLDEIYLAFHMRSPGETVFGNRKDDSPYVTEHVRKFLNSLYPDSNIYETGGFSIH CCCCCCHHEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCEEEE TTIAEPVQAELSKIVKNYLDNIQKSGLVRKTKLTDNKNSSETAVFRKYVQDISPALELFI EHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHEEEE DTDSFGGKSESGLQVALVAVDPATGEILLMHGGSEFKADNQLDRTTAMKRQTGSSIKPIL CCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHH YSAAIETELISASSRILDAPLIYRNQTGNWMPENIGNQYDGDISVRHALAKSKNTAAVQI HHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHCCCCCCCCHHHHHHHHHCCCCHHHHH AEKLGISKIQDFFQKYFFPDPKVLQSRFRGDLSLALGSLEISPLEMALAYSAFANDGTIK HHHHCHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCC RPYLIQKITDRSGKIVYERKSTDEFGLKVPEERKVLSSQVAEIMIDLLHGSANSAGVRST CCHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC GYRGEVAGKTGTTNDNRDNWFVGVKPGMSMAIWLGYDDPSYGLGSSALGGTVAAPLWGSV CCCCEECCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHH AKTFEATEDEKRKYPVTEHAISITVCEESGKLPGPFCKHPRKELFKNGTVPSEICPLNHG HHHHHCCCHHHHCCCCCHHEEEEEEECCCCCCCCHHHCCCHHHHHHCCCCCHHHCCCCCC TDVKREVLRNVF CHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA