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The map label for this gene is aofA

Identifier: 116327076

GI number: 116327076

Start: 297772

End: 299109

Strand: Direct

Name: aofA

Synonym: LBL_0249

Alternate gene names: NA

Gene position: 297772-299109 (Clockwise)

Preceding gene: 116327068

Following gene: 116327082

Centisome position: 8.24

GC content: 42.6

Gene sequence:

>1338_bases
ATGAAACTAAGTAGATCTGAGTTTATCAAACTTTTGACCGCGGCGGGTATTTCCGGCTTTTCAGGGATAAAATTAAGCGC
TCAAGGCATGTCTCCTCGGAAAACAGTAATCGTATTAGGGGGTGGAATTGCCGGTTTGTACACTTCTTATCTCTTGGGCA
AAACGGGAATCAAAGTCCAACTCATTGAGGCGACGGATCGATTGGGGGGTAGAATCAGAACGGTTACCGATGTAAGCGGA
AATTTTTTGGATTTGGGCGCCGAATGGATTCAGGCCGAACACAAAACCGCTAAGAGTTTAATTCGAGAGTTGAGTCTAAA
AACGACCGATTTTGAGGTTCAGTCCGATTTGTTTTTCGGATCGTATCGTAAATTCGGAACCTGGGATATATCGCTTAAGT
CCCAAGAAATTTTAAATAAACTCGTTCAGATGAATGCAAAGATCAATTCTTCGCAACAACAGGAATTGGATCGGATCAGC
TTTTATAATTTTCTAACTTATCAAGGGATGACTCCCGAGGATTTAAAACTTCTGAATTTTAAATATTCCTTATATTATGG
AGATTCACTTCGTTCTTTATCGGCGCAAAAGGTTTTATCCGATCTGGTTAACTTTCCGAAATACGATACCAGAGTGGAAG
GTGGAATGGAATCTTTAACGAAGGCGCTTGTGTTGTCTTTGGAAAATACGGAAGTAACTTTTATGGATCCTGTTGTTTCC
GTTTTTCAGGGAGAAGGTAAAGTGACCGTGACTACGGCGTCCGGCAAACGAATAGAAGGGGGCGCTTGCATTTCGACTTT
GCCTGCAAATCAACTAACGTCGATTCAGTGGGAGCCTGAATTGGATAAGGAAAAGAAACTATCCGCATTGCGAATTCGAT
ATTCCAGAATTTATAAGACTTTTTTAATGCTTCGGGAGGCTCCTTGGACAAAAGGAAATTTTTCGGCGTATTCGGATTCC
GCCGCAGGTTTTATCTACGACGCCGGAACTAAAACAAACTCGGAAGATAAGGTTCTCGGAATGATTTCTACCGGAGATCG
ATACGACGTTTTAGCTTCTTCAACCGATGCGATGAAAGTCGAATACATACGTCTTGCGCTGGAATGTTTGGGACAAAATA
AAGATTTACAGGTCCTTCGGATTCAAAGTAGCGAAACTTCCCAATCCAAATATGTTCCGACCGGTATCGCGACTTTTCCG
CCCGGAAGTTATGGATCGATCATCTCTTTGTTAAAACCGGTGGATCGAATATTCTTTGCGGGGGAACATACTGCGGATTT
GAATGGAACAGTGGAAGGTGCGCTTTCGTCTGCGATTCGTGCTGTCAATCAGATTTGA

Upstream 100 bases:

>100_bases
ATTTCAAGAAAGTACTTTCAAAATCTTTTCTACAAAACCAATTTTTAACCGAAAATAAAAAATGGAATACAACCTTTCCA
AATTTAAATCGGACAATCCA

Downstream 100 bases:

>100_bases
ATGAAGCGTGTCTTCTTTTATCGCTTCAGTTTAAAATATTCAAGGTTAAGAGGAAGCGGATTACTTTGTTGTCTTATCGG
GCGTACAAACGAACATGAAA

Product: amine oxidase (flavin-containing)

Products: 2-oxo acid; NH3; H2O2

Alternate protein names: Twin-Arginine Translocation Pathway Signal; L-Amino Acid Oxidase; Putrescine Oxidase; Amine Oxidase Flavin-Containing; Flavin-Containing Amine Oxidase; Oxidoreductase; Flavin-Containing Monoamine Oxidase; UDP-Galactopyranose Mutase; Flavin-Containing Monoamine Oxidase AofH; Monoamine Oxidase; Fad-Dependent Amine Oxidoreductase

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MKLSRSEFIKLLTAAGISGFSGIKLSAQGMSPRKTVIVLGGGIAGLYTSYLLGKTGIKVQLIEATDRLGGRIRTVTDVSG
NFLDLGAEWIQAEHKTAKSLIRELSLKTTDFEVQSDLFFGSYRKFGTWDISLKSQEILNKLVQMNAKINSSQQQELDRIS
FYNFLTYQGMTPEDLKLLNFKYSLYYGDSLRSLSAQKVLSDLVNFPKYDTRVEGGMESLTKALVLSLENTEVTFMDPVVS
VFQGEGKVTVTTASGKRIEGGACISTLPANQLTSIQWEPELDKEKKLSALRIRYSRIYKTFLMLREAPWTKGNFSAYSDS
AAGFIYDAGTKTNSEDKVLGMISTGDRYDVLASSTDAMKVEYIRLALECLGQNKDLQVLRIQSSETSQSKYVPTGIATFP
PGSYGSIISLLKPVDRIFFAGEHTADLNGTVEGALSSAIRAVNQI

Sequences:

>Translated_445_residues
MKLSRSEFIKLLTAAGISGFSGIKLSAQGMSPRKTVIVLGGGIAGLYTSYLLGKTGIKVQLIEATDRLGGRIRTVTDVSG
NFLDLGAEWIQAEHKTAKSLIRELSLKTTDFEVQSDLFFGSYRKFGTWDISLKSQEILNKLVQMNAKINSSQQQELDRIS
FYNFLTYQGMTPEDLKLLNFKYSLYYGDSLRSLSAQKVLSDLVNFPKYDTRVEGGMESLTKALVLSLENTEVTFMDPVVS
VFQGEGKVTVTTASGKRIEGGACISTLPANQLTSIQWEPELDKEKKLSALRIRYSRIYKTFLMLREAPWTKGNFSAYSDS
AAGFIYDAGTKTNSEDKVLGMISTGDRYDVLASSTDAMKVEYIRLALECLGQNKDLQVLRIQSSETSQSKYVPTGIATFP
PGSYGSIISLLKPVDRIFFAGEHTADLNGTVEGALSSAIRAVNQI
>Mature_445_residues
MKLSRSEFIKLLTAAGISGFSGIKLSAQGMSPRKTVIVLGGGIAGLYTSYLLGKTGIKVQLIEATDRLGGRIRTVTDVSG
NFLDLGAEWIQAEHKTAKSLIRELSLKTTDFEVQSDLFFGSYRKFGTWDISLKSQEILNKLVQMNAKINSSQQQELDRIS
FYNFLTYQGMTPEDLKLLNFKYSLYYGDSLRSLSAQKVLSDLVNFPKYDTRVEGGMESLTKALVLSLENTEVTFMDPVVS
VFQGEGKVTVTTASGKRIEGGACISTLPANQLTSIQWEPELDKEKKLSALRIRYSRIYKTFLMLREAPWTKGNFSAYSDS
AAGFIYDAGTKTNSEDKVLGMISTGDRYDVLASSTDAMKVEYIRLALECLGQNKDLQVLRIQSSETSQSKYVPTGIATFP
PGSYGSIISLLKPVDRIFFAGEHTADLNGTVEGALSSAIRAVNQI

Specific function: Unknown

COG id: COG1231

COG function: function code E; Monoamine oxidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4557735, Length=451, Percent_Identity=23.5033259423503, Blast_Score=100, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.4.3.2

Molecular weight: Translated: 48998; Mature: 48998

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSRSEFIKLLTAAGISGFSGIKLSAQGMSPRKTVIVLGGGIAGLYTSYLLGKTGIKVQ
CCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEE
LIEATDRLGGRIRTVTDVSGNFLDLGAEWIQAEHKTAKSLIRELSLKTTDFEVQSDLFFG
EEECHHHCCCEEEEEEECCCCHHHHCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEC
SYRKFGTWDISLKSQEILNKLVQMNAKINSSQQQELDRISFYNFLTYQGMTPEDLKLLNF
CCCCCCEEEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEECCCCCCCEEEEEE
KYSLYYGDSLRSLSAQKVLSDLVNFPKYDTRVEGGMESLTKALVLSLENTEVTFMDPVVS
EEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHEEEECCCEEEEHHHHHH
VFQGEGKVTVTTASGKRIEGGACISTLPANQLTSIQWEPELDKEKKLSALRIRYSRIYKT
HHCCCCCEEEEECCCCEECCCCEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
FLMLREAPWTKGNFSAYSDSAAGFIYDAGTKTNSEDKVLGMISTGDRYDVLASSTDAMKV
HHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCEEEEECCCCHHHH
EYIRLALECLGQNKDLQVLRIQSSETSQSKYVPTGIATFPPGSYGSIISLLKPVDRIFFA
HHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEC
GEHTADLNGTVEGALSSAIRAVNQI
CCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLSRSEFIKLLTAAGISGFSGIKLSAQGMSPRKTVIVLGGGIAGLYTSYLLGKTGIKVQ
CCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEE
LIEATDRLGGRIRTVTDVSGNFLDLGAEWIQAEHKTAKSLIRELSLKTTDFEVQSDLFFG
EEECHHHCCCEEEEEEECCCCHHHHCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEC
SYRKFGTWDISLKSQEILNKLVQMNAKINSSQQQELDRISFYNFLTYQGMTPEDLKLLNF
CCCCCCEEEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEECCCCCCCEEEEEE
KYSLYYGDSLRSLSAQKVLSDLVNFPKYDTRVEGGMESLTKALVLSLENTEVTFMDPVVS
EEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHEEEECCCEEEEHHHHHH
VFQGEGKVTVTTASGKRIEGGACISTLPANQLTSIQWEPELDKEKKLSALRIRYSRIYKT
HHCCCCCEEEEECCCCEECCCCEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
FLMLREAPWTKGNFSAYSDSAAGFIYDAGTKTNSEDKVLGMISTGDRYDVLASSTDAMKV
HHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCEEEEECCCCHHHH
EYIRLALECLGQNKDLQVLRIQSSETSQSKYVPTGIATFPPGSYGSIISLLKPVDRIFFA
HHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEC
GEHTADLNGTVEGALSSAIRAVNQI
CCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-amino acid; H2O; O2

Specific reaction: an L-amino acid + H2O + O2 = a 2-oxo acid + NH3 + H2O2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA