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The map label for this gene is eriC [C]

Identifier: 116327066

GI number: 116327066

Start: 285762

End: 287642

Strand: Direct

Name: eriC [C]

Synonym: LBL_0239

Alternate gene names: 116327066

Gene position: 285762-287642 (Clockwise)

Preceding gene: 116327065

Following gene: 116327067

Centisome position: 7.91

GC content: 43.75

Gene sequence:

>1881_bases
ATGGAAAAAGTAAAACAACCCATTTTTCGAATCAGCGGCAGAAGATCCTTATACTTTTATTGTATTCTTACCGGAATCGT
TTCCGGGTTGGGGGCCTTTTTATTTTCAAGAATTCTTGCCGTATGCGAATACTTATTTTTAGATCGTGCGGCAGGTCTTT
CGCTTCCACATGCTTCCGGAGAATTTCTCATCGATTCCAACGACACATTACATTGGGGAATTCCTTTTTCGGATGAATAT
AGACCTTGGGTTTTGTTTTTTCTTCCAATCATCGGAGGATTACTTACCGGTTGGATCGTAAACCGTTTTTCACCCGAATC
GGGGGGAACGGGTTCGGATGCGATGATCGATTCCTTTCACAATCAGGAAGGGAGAATGAATCCCGTCGTTTCACTCGTCA
AGTCCATCGCGACTGTTTTTACACTAGCAAGTGGAGGGAGCGGCGGAAAAGAAGGTCCGATCTCACAAATCGGAGCGGGT
TTCGGATCCTTACTTGCTACTCTTTTGAAAGCCGGAGCAAGAGCGAGACGAACACTTTTACTTGCCGGGACGGCGGGAGG
TTTAGGCGCGATCTTTCATGCTCCGTTGGGGGGGGCGTTGACGTCGGTGGAAATGATCTATCGGGAGGATATCGAAAGTG
ATTCTTTGATTCCCTGTATTATTTCTTCGGTTTCTGCTTACTTAGTGTATTCCGGCCTGAACGGTTTTAATACGGTGTAT
CGAGTTACCGGCACTGAATTTTTGAGGTATACCGATTTGATTTTTTATTTAGGTCTGGGGGTTCTTTGTTTTCTGTGCGG
GGATATATTCATTAGGATTTTTAGAAAGGTGCAGAACTTTTCCGCGCATCTCAAGATTTCTCCGATTTTGAAACCTGCGT
TAGGCGGCATATTTGTGGGAATCGTCGGGCTTTTTTTACCGGAAACGATCGGAACCGGAGCGGGAATCCTTCAAGTCGCA
TTGGACGGAAAGGATCCCGTCGGAGCATCGGGAATCTTTTCGTCGGTGTTTCAAAGTTCAGGACTTTGGTTGGTCGCGTT
GTTTTTTATTTTAGCGGGAGTTAAAATTCTTACCACTTCGTTTACCGTCGGAACCGGAGGTTCTGCGGGAATGTTCGGGC
CTTCTCTTTTTATCGGAGGAATGTTAGGCGGAGGAGTCGGAACTTTTGCAAAGATTTTCGTTTATCCCGATCTTTCCGTT
ACGTCGTTCATTTTGGTGGGAATGGGGGCCTTTTACGCGGGTGTTGCAAGTGCTCCAATTGCGGGAATGATTATGATCTG
TGAAATGATCGGAAGTTACATGTTGCTTCCCCCTTTGATGGTGGTTTCGATTTTAACGTTTGTGTTAAGTCACAAATTGA
GTTTATATCGTGCACAGAAAGAAACAAGATTTCAATCTCCCGCACATTTTTGGGATATGAACCGAGACTTTTTGGAAGAA
ATTCAAGTCAAAACTTGTACAAATCGGTTGCGAACAATTGCGGTAACTCGGGATCATTTTTTGCTTTCTGAACTTGAGGA
AGAGGCGTTAAAAATTCAAGCGAGTGACTACGTGGTTCTCGATCGGGAAAATCGATATCTGGGAATTTTATCTCTTCGAA
AAGCAAGACATACTCTCGAATCCAGAGACGTCATCGGCAATTTAATTACTGTTGGAGATGTTACGGATGTTTCGGCTCCG
TTTGGAAAGCTGGAAGACTCTTTAGCCACTCTTTTAAAGATCTTGATCGATCGGGATCTGGATAAAATCGCGATCGTCGA
GGAGAATCAGTTTATCGGATATCTTCGTTTTGCGGATCTCATGAAAATATATTTCGAAAATACCTTTTCTAAAAGTGCAA
AATCGTCGGATTCTGCTCCGAAAATTAAGATATACCTTTAA

Upstream 100 bases:

>100_bases
GACAAAGTAGGATTTTGAAGTTCTAGAAATTTTAGAGTTGGTCCTAAAAATAAGATCAAAACTTTAAATTTCTTTGAGAA
TGACCGACGCAGTTATGAAG

Downstream 100 bases:

>100_bases
AATGAGACGGGTTCCGATCTAAATTTTTAGTTTATGTTTTTCTTATGTATTTAGTCTTAACTGTTTGGGAAAAGGGTTGA
CCCAATCCGGAATCAATGTT

Product: chloride channel protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 626; Mature: 626

Protein sequence:

>626_residues
MEKVKQPIFRISGRRSLYFYCILTGIVSGLGAFLFSRILAVCEYLFLDRAAGLSLPHASGEFLIDSNDTLHWGIPFSDEY
RPWVLFFLPIIGGLLTGWIVNRFSPESGGTGSDAMIDSFHNQEGRMNPVVSLVKSIATVFTLASGGSGGKEGPISQIGAG
FGSLLATLLKAGARARRTLLLAGTAGGLGAIFHAPLGGALTSVEMIYREDIESDSLIPCIISSVSAYLVYSGLNGFNTVY
RVTGTEFLRYTDLIFYLGLGVLCFLCGDIFIRIFRKVQNFSAHLKISPILKPALGGIFVGIVGLFLPETIGTGAGILQVA
LDGKDPVGASGIFSSVFQSSGLWLVALFFILAGVKILTTSFTVGTGGSAGMFGPSLFIGGMLGGGVGTFAKIFVYPDLSV
TSFILVGMGAFYAGVASAPIAGMIMICEMIGSYMLLPPLMVVSILTFVLSHKLSLYRAQKETRFQSPAHFWDMNRDFLEE
IQVKTCTNRLRTIAVTRDHFLLSELEEEALKIQASDYVVLDRENRYLGILSLRKARHTLESRDVIGNLITVGDVTDVSAP
FGKLEDSLATLLKILIDRDLDKIAIVEENQFIGYLRFADLMKIYFENTFSKSAKSSDSAPKIKIYL

Sequences:

>Translated_626_residues
MEKVKQPIFRISGRRSLYFYCILTGIVSGLGAFLFSRILAVCEYLFLDRAAGLSLPHASGEFLIDSNDTLHWGIPFSDEY
RPWVLFFLPIIGGLLTGWIVNRFSPESGGTGSDAMIDSFHNQEGRMNPVVSLVKSIATVFTLASGGSGGKEGPISQIGAG
FGSLLATLLKAGARARRTLLLAGTAGGLGAIFHAPLGGALTSVEMIYREDIESDSLIPCIISSVSAYLVYSGLNGFNTVY
RVTGTEFLRYTDLIFYLGLGVLCFLCGDIFIRIFRKVQNFSAHLKISPILKPALGGIFVGIVGLFLPETIGTGAGILQVA
LDGKDPVGASGIFSSVFQSSGLWLVALFFILAGVKILTTSFTVGTGGSAGMFGPSLFIGGMLGGGVGTFAKIFVYPDLSV
TSFILVGMGAFYAGVASAPIAGMIMICEMIGSYMLLPPLMVVSILTFVLSHKLSLYRAQKETRFQSPAHFWDMNRDFLEE
IQVKTCTNRLRTIAVTRDHFLLSELEEEALKIQASDYVVLDRENRYLGILSLRKARHTLESRDVIGNLITVGDVTDVSAP
FGKLEDSLATLLKILIDRDLDKIAIVEENQFIGYLRFADLMKIYFENTFSKSAKSSDSAPKIKIYL
>Mature_626_residues
MEKVKQPIFRISGRRSLYFYCILTGIVSGLGAFLFSRILAVCEYLFLDRAAGLSLPHASGEFLIDSNDTLHWGIPFSDEY
RPWVLFFLPIIGGLLTGWIVNRFSPESGGTGSDAMIDSFHNQEGRMNPVVSLVKSIATVFTLASGGSGGKEGPISQIGAG
FGSLLATLLKAGARARRTLLLAGTAGGLGAIFHAPLGGALTSVEMIYREDIESDSLIPCIISSVSAYLVYSGLNGFNTVY
RVTGTEFLRYTDLIFYLGLGVLCFLCGDIFIRIFRKVQNFSAHLKISPILKPALGGIFVGIVGLFLPETIGTGAGILQVA
LDGKDPVGASGIFSSVFQSSGLWLVALFFILAGVKILTTSFTVGTGGSAGMFGPSLFIGGMLGGGVGTFAKIFVYPDLSV
TSFILVGMGAFYAGVASAPIAGMIMICEMIGSYMLLPPLMVVSILTFVLSHKLSLYRAQKETRFQSPAHFWDMNRDFLEE
IQVKTCTNRLRTIAVTRDHFLLSELEEEALKIQASDYVVLDRENRYLGILSLRKARHTLESRDVIGNLITVGDVTDVSAP
FGKLEDSLATLLKILIDRDLDKIAIVEENQFIGYLRFADLMKIYFENTFSKSAKSSDSAPKIKIYL

Specific function: Unknown

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081943, Length=450, Percent_Identity=27.7777777777778, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786350, Length=362, Percent_Identity=27.9005524861878, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 67876; Mature: 67876

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKVKQPIFRISGRRSLYFYCILTGIVSGLGAFLFSRILAVCEYLFLDRAAGLSLPHASG
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EFLIDSNDTLHWGIPFSDEYRPWVLFFLPIIGGLLTGWIVNRFSPESGGTGSDAMIDSFH
CEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHC
NQEGRMNPVVSLVKSIATVFTLASGGSGGKEGPISQIGAGFGSLLATLLKAGARARRTLL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHCCCHHCEEEE
LAGTAGGLGAIFHAPLGGALTSVEMIYREDIESDSLIPCIISSVSAYLVYSGLNGFNTVY
EEECCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEE
RVTGTEFLRYTDLIFYLGLGVLCFLCGDIFIRIFRKVQNFSAHLKISPILKPALGGIFVG
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHH
IVGLFLPETIGTGAGILQVALDGKDPVGASGIFSSVFQSSGLWLVALFFILAGVKILTTS
HHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHEE
FTVGTGGSAGMFGPSLFIGGMLGGGVGTFAKIFVYPDLSVTSFILVGMGAFYAGVASAPI
EEECCCCCCCCCCHHHHHHHHHCCCHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHCCCH
AGMIMICEMIGSYMLLPPLMVVSILTFVLSHKLSLYRAQKETRFQSPAHFWDMNRDFLEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHH
IQVKTCTNRLRTIAVTRDHFLLSELEEEALKIQASDYVVLDRENRYLGILSLRKARHTLE
HHHHHHHHHHHEEEEEHHHHHHHHHHHHHHEEECCCEEEEECCCCEEEHHHHHHHHHHHH
SRDVIGNLITVGDVTDVSAPFGKLEDSLATLLKILIDRDLDKIAIVEENQFIGYLRFADL
HHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHH
MKIYFENTFSKSAKSSDSAPKIKIYL
HHHHHHHHHHHCCCCCCCCCEEEEEC
>Mature Secondary Structure
MEKVKQPIFRISGRRSLYFYCILTGIVSGLGAFLFSRILAVCEYLFLDRAAGLSLPHASG
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EFLIDSNDTLHWGIPFSDEYRPWVLFFLPIIGGLLTGWIVNRFSPESGGTGSDAMIDSFH
CEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHC
NQEGRMNPVVSLVKSIATVFTLASGGSGGKEGPISQIGAGFGSLLATLLKAGARARRTLL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHCCCHHCEEEE
LAGTAGGLGAIFHAPLGGALTSVEMIYREDIESDSLIPCIISSVSAYLVYSGLNGFNTVY
EEECCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEE
RVTGTEFLRYTDLIFYLGLGVLCFLCGDIFIRIFRKVQNFSAHLKISPILKPALGGIFVG
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHH
IVGLFLPETIGTGAGILQVALDGKDPVGASGIFSSVFQSSGLWLVALFFILAGVKILTTS
HHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHEE
FTVGTGGSAGMFGPSLFIGGMLGGGVGTFAKIFVYPDLSVTSFILVGMGAFYAGVASAPI
EEECCCCCCCCCCHHHHHHHHHCCCHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHCCCH
AGMIMICEMIGSYMLLPPLMVVSILTFVLSHKLSLYRAQKETRFQSPAHFWDMNRDFLEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHH
IQVKTCTNRLRTIAVTRDHFLLSELEEEALKIQASDYVVLDRENRYLGILSLRKARHTLE
HHHHHHHHHHHEEEEEHHHHHHHHHHHHHHEEECCCEEEEECCCCEEEHHHHHHHHHHHH
SRDVIGNLITVGDVTDVSAPFGKLEDSLATLLKILIDRDLDKIAIVEENQFIGYLRFADL
HHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHH
MKIYFENTFSKSAKSSDSAPKIKIYL
HHHHHHHHHHHCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]