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The map label for this gene is holA

Identifier: 116326866

GI number: 116326866

Start: 18819

End: 19907

Strand: Reverse

Name: holA

Synonym: LBL_0015

Alternate gene names: NA

Gene position: 19907-18819 (Counterclockwise)

Preceding gene: 116326868

Following gene: 116326863

Centisome position: 0.55

GC content: 37.01

Gene sequence:

>1089_bases
ATGGCGACAAAAGCAAAAGAATATAAAAATTCCATAGAATTTCTGACCGATTGGAGTGAAAAACTACCGCAAATCGTTTT
TGTTGCGGCTAAAGAATCCTACGAGTTTGAAATTATCGCGGAAAAATATAAGGAAGAAATTCGAAAAACGGGAGAACCAT
TCGAAATCGTAATATTCGTTTCGGAACCGGGAGACTTTGAAAGATTCCAATCCGACGCTTTCAATCTGGATATGTTTTCC
AATCGAAAATTATTTATCGTAAAATCCGGTCTTGAATTTTTTAAGCCGATCTCAAGCGGAAAAGGAAAGAATAACGAATC
TTTACAAAAACGATTTTCAAACTTTCCGAACTCGATCCAACTTTTAATTCATTATAATCACTGGGAAGTTCCAAACAAGA
TCCTTCAAATCTTCGGGGGAAAAGCAAATCTCATCAAAACCAAAAATTTTTATCCTAACGAAACACGCGCTGGTCTTTTG
CAAGCTTGTAAAGAAATTGGAGTTCAATTGGACGAGGACGCCATAAATGAATTCCTACACAAAATTCCTCCCTCAATGGG
AGCGTATCTACAATCACTTTCTAAACTAAAACTTTATCTCGTAAAAAAATCCTTCACGAAACAAGACGTTGAAGACGTCT
TGCTTTTCAGCGGGGAATTAAATTCTTCCGGCTTGGTTGACTTTTTTATGGAATCGGATCGAATCCGTTTTTTCAAAGAA
CTGAAAAAATTCCAGAGCGGGAAAGATTCTTTACTTTTATTTCTTTCAATCCTGAAAGAAAGAGTCGATCAACTTCGGAA
ATATAAAATCATCTCCAGAAAATACGAGACATCCCTTTCAGACGAGGAAATCCACGAATTCTTGGATATTCAATCTTATA
GCCCCGCAAGGAAAAATTTCGTTCGAAATCGCCTCAGAAAAGAAGCTACCTTTTTTTCCGATAAAATCATCGGAGAACTT
TACGATTTTATGATAGATATGAATATTCGAATCAAAACCGGTTCGGAAAAAGAAGGGGCGGAGTTTTATTTCAGTCGCCG
GATGGAGGATTTTTTCCTTCAGCTTCGCCGGAAAGACCGAATTCTATAA

Upstream 100 bases:

>100_bases
GAACTGATATTCATATTCTAATCTTCGGAGAATTGATCCTTTACTTTAAATAATTCTTCGGTTTTTTTAAGGACCGGAAC
GATTTTTCAATTTAAATAGA

Downstream 100 bases:

>100_bases
TCTTTCTATAAATCGTCCTTTCCGATATTCCGAGTATTTTGGCGGCCTTTTCCCGATTTCCGTTCACAAGAATCAAATTC
CTTTTGATGATTTCCCTTTC

Product: DNA-directed DNA polymerase, delta subunit

Products: diphosphate; DNAn+1

Alternate protein names: DNA-Directed DNA Polymerase Delta Subunit

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MATKAKEYKNSIEFLTDWSEKLPQIVFVAAKESYEFEIIAEKYKEEIRKTGEPFEIVIFVSEPGDFERFQSDAFNLDMFS
NRKLFIVKSGLEFFKPISSGKGKNNESLQKRFSNFPNSIQLLIHYNHWEVPNKILQIFGGKANLIKTKNFYPNETRAGLL
QACKEIGVQLDEDAINEFLHKIPPSMGAYLQSLSKLKLYLVKKSFTKQDVEDVLLFSGELNSSGLVDFFMESDRIRFFKE
LKKFQSGKDSLLLFLSILKERVDQLRKYKIISRKYETSLSDEEIHEFLDIQSYSPARKNFVRNRLRKEATFFSDKIIGEL
YDFMIDMNIRIKTGSEKEGAEFYFSRRMEDFFLQLRRKDRIL

Sequences:

>Translated_362_residues
MATKAKEYKNSIEFLTDWSEKLPQIVFVAAKESYEFEIIAEKYKEEIRKTGEPFEIVIFVSEPGDFERFQSDAFNLDMFS
NRKLFIVKSGLEFFKPISSGKGKNNESLQKRFSNFPNSIQLLIHYNHWEVPNKILQIFGGKANLIKTKNFYPNETRAGLL
QACKEIGVQLDEDAINEFLHKIPPSMGAYLQSLSKLKLYLVKKSFTKQDVEDVLLFSGELNSSGLVDFFMESDRIRFFKE
LKKFQSGKDSLLLFLSILKERVDQLRKYKIISRKYETSLSDEEIHEFLDIQSYSPARKNFVRNRLRKEATFFSDKIIGEL
YDFMIDMNIRIKTGSEKEGAEFYFSRRMEDFFLQLRRKDRIL
>Mature_361_residues
ATKAKEYKNSIEFLTDWSEKLPQIVFVAAKESYEFEIIAEKYKEEIRKTGEPFEIVIFVSEPGDFERFQSDAFNLDMFSN
RKLFIVKSGLEFFKPISSGKGKNNESLQKRFSNFPNSIQLLIHYNHWEVPNKILQIFGGKANLIKTKNFYPNETRAGLLQ
ACKEIGVQLDEDAINEFLHKIPPSMGAYLQSLSKLKLYLVKKSFTKQDVEDVLLFSGELNSSGLVDFFMESDRIRFFKEL
KKFQSGKDSLLLFLSILKERVDQLRKYKIISRKYETSLSDEEIHEFLDIQSYSPARKNFVRNRLRKEATFFSDKIIGELY
DFMIDMNIRIKTGSEKEGAEFYFSRRMEDFFLQLRRKDRIL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.7

Molecular weight: Translated: 42603; Mature: 42471

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATKAKEYKNSIEFLTDWSEKLPQIVFVAAKESYEFEIIAEKYKEEIRKTGEPFEIVIFV
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEE
SEPGDFERFQSDAFNLDMFSNRKLFIVKSGLEFFKPISSGKGKNNESLQKRFSNFPNSIQ
ECCCCHHHHHCCCCCEEEECCCEEEEEECCHHHHHHHHCCCCCCHHHHHHHHHCCCCEEE
LLIHYNHWEVPNKILQIFGGKANLIKTKNFYPNETRAGLLQACKEIGVQLDEDAINEFLH
EEEEECCCCHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
KIPPSMGAYLQSLSKLKLYLVKKSFTKQDVEDVLLFSGELNSSGLVDFFMESDRIRFFKE
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHH
LKKFQSGKDSLLLFLSILKERVDQLRKYKIISRKYETSLSDEEIHEFLDIQSYSPARKNF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHH
VRNRLRKEATFFSDKIIGELYDFMIDMNIRIKTGSEKEGAEFYFSRRMEDFFLQLRRKDR
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCC
IL
CC
>Mature Secondary Structure 
ATKAKEYKNSIEFLTDWSEKLPQIVFVAAKESYEFEIIAEKYKEEIRKTGEPFEIVIFV
CCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEE
SEPGDFERFQSDAFNLDMFSNRKLFIVKSGLEFFKPISSGKGKNNESLQKRFSNFPNSIQ
ECCCCHHHHHCCCCCEEEECCCEEEEEECCHHHHHHHHCCCCCCHHHHHHHHHCCCCEEE
LLIHYNHWEVPNKILQIFGGKANLIKTKNFYPNETRAGLLQACKEIGVQLDEDAINEFLH
EEEEECCCCHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
KIPPSMGAYLQSLSKLKLYLVKKSFTKQDVEDVLLFSGELNSSGLVDFFMESDRIRFFKE
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHH
LKKFQSGKDSLLLFLSILKERVDQLRKYKIISRKYETSLSDEEIHEFLDIQSYSPARKNF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHH
VRNRLRKEATFFSDKIIGELYDFMIDMNIRIKTGSEKEGAEFYFSRRMEDFFLQLRRKDR
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCC
IL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA