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The map label for this gene is agpA [H]

Identifier: 116249442

GI number: 116249442

Start: 850501

End: 852438

Strand: Direct

Name: agpA [H]

Synonym: pRL120780

Alternate gene names: 116249442

Gene position: 850501-852438 (Clockwise)

Preceding gene: 116249432

Following gene: 116249443

Centisome position: 97.76

GC content: 60.99

Gene sequence:

>1938_bases
ATGGCCAAAGAAATACTGTCGCGCGGCGTCACCCGCCGCGCCGTGCTTGGTGGCATGGCTGGTGTCGCGGCGCTGTCTAT
CGCCGGTCGCGTGTCTGCCGCAGGCGGTGAAGCGCCGGCCCTTGCGCAGCTCGCCAAGGATGGAAAGCTGCCGCCGCTCG
CCGAGCGCCTGCCGAAAAAGCCGATGGTCGTGACGCCGTTCGAGAAGGTCGGCACCTATGGCGGTTCGCTGCGTCGCGGC
CTTCGCGGTTCATCCGACCATAACGGCATCCTGCGTATGGTCGGCAACCAGAGCCTTGTGCGCTGGAACCTCGATTTTAC
CGCCGTGCAGCCGAACCTTGCCGAGCGCTGGGAGGTCAGCGACGACGCAACACAATTCACGTTCCATCTCATCGAAGGCG
TGCGCTGGTCCGACGGTCATCCCTTTACGGCCGATGACGTCGTTTTCGCGATCGAAGACTGCGTCAAGAACACCGAGCTC
TACAGCTCGACGCCGGCGCAGCTTGCCGTCGCCGGCAAGCCGGTCACCGTCGAGAAGATCGACGACTATACGGTGAAGTT
CACCTTTGCCGCGGCCAACGCGCTTTACCTGGAAAACCTCGCCACACCGCTTGGCCAGCATCCGACGCTGTTCCCGAAGC
ATTACTGCAGCCAGTTCCTGCCGAAATATAATCCCAATATCGAGGCCGATGCGAAGAAGGCCGGCGTCACCAGTTGGACG
GAGCTGTTCCGCAGCCGTTGCGGCGACATCGAGATCCCGTCGCGATGGGGCAATGTCGACAAGCCGACGCTCGATCCATG
GGTGGTCAAGGAGCCCTATGCCGGCGGCGCGACGCGCGTCGTCATGACCCGCAACCCTTATTTCTGGCAGGTCGATACCG
AGGGCAACCAGCTCCCCTACATCGATGAAATCAACTTCGGCATCTCGCAGGACGTCGAATCGCTGATGCTGAACGTCATC
TCTGGAAAAATCGACATCCAGGAACGTCACATCAGCGTTCTGGCCAACAAGCCGACGCTGTCCAAGAACATGGAAAAGGG
CGATTATCGGCTGCTGACGCTCGTGCCTTCGGCCTCGCAACAGTGCCAGATCTATTTCAACATCACCCACAAAGATCCTG
CCATGCGCAAGATGTTTGCCGACAAGGCGTTCCGGCAAGCGCTTTCGATCGGCATCAATCGCCAGGAGCTCATCGACATC
GTCTATTTCGGACAGAGCGAGCCCTACCAGGCCGGGCCGCGTCCGACCCATCCCTGGTATAACGAGACATACGCGCGCCA
ATTCACCGAATTCGACGCCGACAAGGCAGGCGCGATGCTCGATGAGGCCGGCTATAAGAAAGGCGGCGACGGTTTCCGCC
TCCGGCCCGACGGCCAGAAGGTGTTCTTCTCGATCGACGTCATTCCGACCCTCTATCCCGACCTCGTCGATGCACTGGAA
CTGGTCAAGGCGCATTGGGCTCAGATCGGTATCGACATGAAGGTCAACACGATCGAGCGGGCGCTCTATTACACCCGCGG
CGACGACAACGCCCATGATGCGGCGGTGTGGCCGGGTCCTGGCGGTCTCGATCCGATGCTCGATCCGCGCGATTTCTTCG
CCTTCCATCCGCAGGGTTCGCGGTACGCCATTCCATGGACGCTTTGGTACACCTCCAACGGTGCACGCGGCGAAGAGCCG
CCGGAAAGCCAGAAGAAGCGCATGATGCTCTTCGACGAAGCGCGTTCGACGGCCGATCTCGACAAGCGCGGTGCGATCAT
GAAGCAGATCTTCGACATCGCGGCCGAGGAATTCGAGACCGTCGGCCTTTGCCTTGCCGTCGGCGGCTTCGGCATCATCC
GCAACAATCTGCGCAATGTTCCCGAGAAGGAGCCGGATAGCTGGTCCTGGCCCAATCCCGGTCCGGCAATGCCGCAGCAA
TTCACCTTCACGAGCTGA

Upstream 100 bases:

>100_bases
TGGTTTCGGTCGTAGCGCCGAGGAGGGCGTCAGCGTCGGGTCGGGAGCCCGCCGCATCAGCCGGTGCAAAGGCTGCGCCG
GCACAAAAGGGAGGAATTCG

Downstream 100 bases:

>100_bases
TTTTCGTCTTGAGCGCCGTGCCATCAGGTACGGCGCTTTCTTTCAGTACGCCCTCCGAGATGCCTTGCCGGTCCTGACCG
CCGACAAGGCCCGGGAGGCG

Product: putative substrate-binding component of ABC transporter

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 645; Mature: 644

Protein sequence:

>645_residues
MAKEILSRGVTRRAVLGGMAGVAALSIAGRVSAAGGEAPALAQLAKDGKLPPLAERLPKKPMVVTPFEKVGTYGGSLRRG
LRGSSDHNGILRMVGNQSLVRWNLDFTAVQPNLAERWEVSDDATQFTFHLIEGVRWSDGHPFTADDVVFAIEDCVKNTEL
YSSTPAQLAVAGKPVTVEKIDDYTVKFTFAAANALYLENLATPLGQHPTLFPKHYCSQFLPKYNPNIEADAKKAGVTSWT
ELFRSRCGDIEIPSRWGNVDKPTLDPWVVKEPYAGGATRVVMTRNPYFWQVDTEGNQLPYIDEINFGISQDVESLMLNVI
SGKIDIQERHISVLANKPTLSKNMEKGDYRLLTLVPSASQQCQIYFNITHKDPAMRKMFADKAFRQALSIGINRQELIDI
VYFGQSEPYQAGPRPTHPWYNETYARQFTEFDADKAGAMLDEAGYKKGGDGFRLRPDGQKVFFSIDVIPTLYPDLVDALE
LVKAHWAQIGIDMKVNTIERALYYTRGDDNAHDAAVWPGPGGLDPMLDPRDFFAFHPQGSRYAIPWTLWYTSNGARGEEP
PESQKKRMMLFDEARSTADLDKRGAIMKQIFDIAAEEFETVGLCLAVGGFGIIRNNLRNVPEKEPDSWSWPNPGPAMPQQ
FTFTS

Sequences:

>Translated_645_residues
MAKEILSRGVTRRAVLGGMAGVAALSIAGRVSAAGGEAPALAQLAKDGKLPPLAERLPKKPMVVTPFEKVGTYGGSLRRG
LRGSSDHNGILRMVGNQSLVRWNLDFTAVQPNLAERWEVSDDATQFTFHLIEGVRWSDGHPFTADDVVFAIEDCVKNTEL
YSSTPAQLAVAGKPVTVEKIDDYTVKFTFAAANALYLENLATPLGQHPTLFPKHYCSQFLPKYNPNIEADAKKAGVTSWT
ELFRSRCGDIEIPSRWGNVDKPTLDPWVVKEPYAGGATRVVMTRNPYFWQVDTEGNQLPYIDEINFGISQDVESLMLNVI
SGKIDIQERHISVLANKPTLSKNMEKGDYRLLTLVPSASQQCQIYFNITHKDPAMRKMFADKAFRQALSIGINRQELIDI
VYFGQSEPYQAGPRPTHPWYNETYARQFTEFDADKAGAMLDEAGYKKGGDGFRLRPDGQKVFFSIDVIPTLYPDLVDALE
LVKAHWAQIGIDMKVNTIERALYYTRGDDNAHDAAVWPGPGGLDPMLDPRDFFAFHPQGSRYAIPWTLWYTSNGARGEEP
PESQKKRMMLFDEARSTADLDKRGAIMKQIFDIAAEEFETVGLCLAVGGFGIIRNNLRNVPEKEPDSWSWPNPGPAMPQQ
FTFTS
>Mature_644_residues
AKEILSRGVTRRAVLGGMAGVAALSIAGRVSAAGGEAPALAQLAKDGKLPPLAERLPKKPMVVTPFEKVGTYGGSLRRGL
RGSSDHNGILRMVGNQSLVRWNLDFTAVQPNLAERWEVSDDATQFTFHLIEGVRWSDGHPFTADDVVFAIEDCVKNTELY
SSTPAQLAVAGKPVTVEKIDDYTVKFTFAAANALYLENLATPLGQHPTLFPKHYCSQFLPKYNPNIEADAKKAGVTSWTE
LFRSRCGDIEIPSRWGNVDKPTLDPWVVKEPYAGGATRVVMTRNPYFWQVDTEGNQLPYIDEINFGISQDVESLMLNVIS
GKIDIQERHISVLANKPTLSKNMEKGDYRLLTLVPSASQQCQIYFNITHKDPAMRKMFADKAFRQALSIGINRQELIDIV
YFGQSEPYQAGPRPTHPWYNETYARQFTEFDADKAGAMLDEAGYKKGGDGFRLRPDGQKVFFSIDVIPTLYPDLVDALEL
VKAHWAQIGIDMKVNTIERALYYTRGDDNAHDAAVWPGPGGLDPMLDPRDFFAFHPQGSRYAIPWTLWYTSNGARGEEPP
ESQKKRMMLFDEARSTADLDKRGAIMKQIFDIAAEEFETVGLCLAVGGFGIIRNNLRNVPEKEPDSWSWPNPGPAMPQQF
TFTS

Specific function: Probably involved in an alpha-galactosides intake transport system [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=514, Percent_Identity=25.6809338521401, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1787551, Length=443, Percent_Identity=23.4762979683973, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 71841; Mature: 71710

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEILSRGVTRRAVLGGMAGVAALSIAGRVSAAGGEAPALAQLAKDGKLPPLAERLPKK
CCHHHHHCCCHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHCCCCCHHHHHCCCC
PMVVTPFEKVGTYGGSLRRGLRGSSDHNGILRMVGNQSLVRWNLDFTAVQPNLAERWEVS
CEEECCHHHHCCCCHHHHHCCCCCCCCCCEEEEECCCEEEEEECEEEEECCCHHHHCCCC
DDATQFTFHLIEGVRWSDGHPFTADDVVFAIEDCVKNTELYSSTPAQLAVAGKPVTVEKI
CCHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHCCCHHCCCCCCEEEECCCCEEEEEC
DDYTVKFTFAAANALYLENLATPLGQHPTLFPKHYCSQFLPKYNPNIEADAKKAGVTSWT
CCEEEEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHCCCHHHH
ELFRSRCGDIEIPSRWGNVDKPTLDPWVVKEPYAGGATRVVMTRNPYFWQVDTEGNQLPY
HHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEECCCEEEEEECCCCCCCC
IDEINFGISQDVESLMLNVISGKIDIQERHISVLANKPTLSKNMEKGDYRLLTLVPSASQ
HHCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCHHCCCCCCCEEEEEEECCCCC
QCQIYFNITHKDPAMRKMFADKAFRQALSIGINRQELIDIVYFGQSEPYQAGPRPTHPWY
CEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEECCCCCCCCCCCCCCCCC
NETYARQFTEFDADKAGAMLDEAGYKKGGDGFRLRPDGQKVFFSIDVIPTLYPDLVDALE
CHHHHHHHHHCCCHHHCCHHHHCCCCCCCCCCEECCCCCEEEEEEEEHHHHHHHHHHHHH
LVKAHWAQIGIDMKVNTIERALYYTRGDDNAHDAAVWPGPGGLDPMLDPRDFFAFHPQGS
HHHHHHHHHCCCEEEHHHHHHHEEECCCCCCCCCEECCCCCCCCCCCCCCHHEEECCCCC
RYAIPWTLWYTSNGARGEEPPESQKKRMMLFDEARSTADLDKRGAIMKQIFDIAAEEFET
EEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VGLCLAVGGFGIIRNNLRNVPEKEPDSWSWPNPGPAMPQQFTFTS
HHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKEILSRGVTRRAVLGGMAGVAALSIAGRVSAAGGEAPALAQLAKDGKLPPLAERLPKK
CHHHHHCCCHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHCCCCCHHHHHCCCC
PMVVTPFEKVGTYGGSLRRGLRGSSDHNGILRMVGNQSLVRWNLDFTAVQPNLAERWEVS
CEEECCHHHHCCCCHHHHHCCCCCCCCCCEEEEECCCEEEEEECEEEEECCCHHHHCCCC
DDATQFTFHLIEGVRWSDGHPFTADDVVFAIEDCVKNTELYSSTPAQLAVAGKPVTVEKI
CCHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHCCCHHCCCCCCEEEECCCCEEEEEC
DDYTVKFTFAAANALYLENLATPLGQHPTLFPKHYCSQFLPKYNPNIEADAKKAGVTSWT
CCEEEEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHCCCHHHH
ELFRSRCGDIEIPSRWGNVDKPTLDPWVVKEPYAGGATRVVMTRNPYFWQVDTEGNQLPY
HHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEECCCEEEEEECCCCCCCC
IDEINFGISQDVESLMLNVISGKIDIQERHISVLANKPTLSKNMEKGDYRLLTLVPSASQ
HHCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCHHCCCCCCCEEEEEEECCCCC
QCQIYFNITHKDPAMRKMFADKAFRQALSIGINRQELIDIVYFGQSEPYQAGPRPTHPWY
CEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEECCCCCCCCCCCCCCCCC
NETYARQFTEFDADKAGAMLDEAGYKKGGDGFRLRPDGQKVFFSIDVIPTLYPDLVDALE
CHHHHHHHHHCCCHHHCCHHHHCCCCCCCCCCEECCCCCEEEEEEEEHHHHHHHHHHHHH
LVKAHWAQIGIDMKVNTIERALYYTRGDDNAHDAAVWPGPGGLDPMLDPRDFFAFHPQGS
HHHHHHHHHCCCEEEHHHHHHHEEECCCCCCCCCEECCCCCCCCCCCCCCHHEEECCCCC
RYAIPWTLWYTSNGARGEEPPESQKKRMMLFDEARSTADLDKRGAIMKQIFDIAAEEFET
EEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VGLCLAVGGFGIIRNNLRNVPEKEPDSWSWPNPGPAMPQQFTFTS
HHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9791127; 11481431 [H]