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The map label for this gene is ttuB [H]

Identifier: 116249282

GI number: 116249282

Start: 670707

End: 672104

Strand: Reverse

Name: ttuB [H]

Synonym: pRL120617

Alternate gene names: 116249282

Gene position: 672104-670707 (Counterclockwise)

Preceding gene: 116249287

Following gene: 116249281

Centisome position: 77.25

GC content: 59.51

Gene sequence:

>1398_bases
ATGGCAGCGCTGCCAAAAAGTGGCATGGCGTGCCGCGGTAGGATCTCAAGGAGACCGCGGCAACAATCGGAGGAGAAAAT
CATGACGCTGCAGACGCAAGCGCCAGTTGTTGGCTTACATCCCGCCCAGACGCTCGAAGACCGTGCCTATGGCAAGGTAT
TCTGGCGCATCGTACCGTTTTTGATGCTGTGCTACGTGGTCGCCTATCTCGACCGCGTCAATGTCGGTTTCGCCAAGCTG
CAGATGTCGAGCGAGCTCGGCCTCTCGGAAGCCGCCTATGGCATCGGCGCCGGCATTTTCTTCATCGGCTATTTTCTGTT
TGAAGTGCCGAGCAACATCATCATGAACAAGGTTGGCGCGCGGGTGTGGATCGCCCGCATCATGGTCACCTGGGGCATCA
TTTCCGCCGCCTTAATGTTCACCTCTTCGGAAACCGTCTTCTATGTCCTCCGTTTCCTGCTGGGCGTTGCCGAAGCCGGA
TTTTTTCCCGGCATCATTCTCTATCTGACCGCGTGGTACCCGGCCCATCGCCGCGCCAGGATCATCACCACCTTCATGTC
CGCGATCCCGATATCCGCCATTTTCGGCAATCCGCTTTCGGGTCTCCTGATGGATAGTTTCCACGGCACGCACGGACTTT
CCGGCTGGCAGTGGATGTTCCTGATCGAAGCCATTCCGGCTATTCTTTTCGGCGTTGCGACGTTCTTCTACCTTGATGAT
ACGATCCAGGGCGCGAAATGGCTGAACGATGAGGAAAAGCGCGTGCTGACGGCCAATATCGAGGCGGAGAACCGGGCCAA
GACAGCAAGCCCGCACAGCATCGGCGCAACGCTGACCGACCGTCGCGTCTGGCTGATGTGCCTGATCTATTTCTGCTTCG
TGCTCGGGCAATATGGCCTGAATTTCTGGATGCCGACCATCGTCAAGGCCTCGGGCGTCAACGGAAACCTCAATATCGGC
CTGATTTCCGCGATCCCCTATATCTGCACATTCGTCGTGATGCTGGCGCTCGGACGTTCCGCCGACAGGCTGCGCGAACG
CCGCTGGCACCTCGTCGTCCCGGCCTTCATCGCCGCCGGTGGGTTCGTCGCGGCGACGATGGCGACGAGCACGACGGTCT
CGATTGTCTGCCTGTCGCTGGCTGCTGCCGGCGCCATCAGTTGCGCGCCGCTGTTCTGGTCGCTTCCGACGGCTTTTCTC
GCCGGCACGGGCGCTGCGGCCGGCATTGCCTGGATCAATTCGGTCGGCAACCTCGCCGGGTTTCTCGGGCCGTTTCTGGT
AGGCTATCTCAAAGACTTTACCGGCACCAACAGCGCCGGCATGTATCTGCTGGCGGCTGCCTTAGTCATTGGTTCGCTGG
CCGTGTTGACGGTTCCGGCGAAAAGCGTCAATCGCTGA

Upstream 100 bases:

>100_bases
CGCTCTGCCCCATCTTTCACCGCTACCGCCAAGAAGCAAGGTTTTTTTGGCAGCGCTACCAATTTGCCGTTGGCAGCGCT
GCCAAAATGGATTAATAAGA

Downstream 100 bases:

>100_bases
ACAATAGCCCCTCCGGGATGGTACCCGGAGGGGCGCAGACCTCTCTCACAAGACTGGAGAAGCTCCTCATGTCACCGCTT
GCTGAAAACTCAGGTCCCGA

Product: MFS family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MAALPKSGMACRGRISRRPRQQSEEKIMTLQTQAPVVGLHPAQTLEDRAYGKVFWRIVPFLMLCYVVAYLDRVNVGFAKL
QMSSELGLSEAAYGIGAGIFFIGYFLFEVPSNIIMNKVGARVWIARIMVTWGIISAALMFTSSETVFYVLRFLLGVAEAG
FFPGIILYLTAWYPAHRRARIITTFMSAIPISAIFGNPLSGLLMDSFHGTHGLSGWQWMFLIEAIPAILFGVATFFYLDD
TIQGAKWLNDEEKRVLTANIEAENRAKTASPHSIGATLTDRRVWLMCLIYFCFVLGQYGLNFWMPTIVKASGVNGNLNIG
LISAIPYICTFVVMLALGRSADRLRERRWHLVVPAFIAAGGFVAATMATSTTVSIVCLSLAAAGAISCAPLFWSLPTAFL
AGTGAAAGIAWINSVGNLAGFLGPFLVGYLKDFTGTNSAGMYLLAAALVIGSLAVLTVPAKSVNR

Sequences:

>Translated_465_residues
MAALPKSGMACRGRISRRPRQQSEEKIMTLQTQAPVVGLHPAQTLEDRAYGKVFWRIVPFLMLCYVVAYLDRVNVGFAKL
QMSSELGLSEAAYGIGAGIFFIGYFLFEVPSNIIMNKVGARVWIARIMVTWGIISAALMFTSSETVFYVLRFLLGVAEAG
FFPGIILYLTAWYPAHRRARIITTFMSAIPISAIFGNPLSGLLMDSFHGTHGLSGWQWMFLIEAIPAILFGVATFFYLDD
TIQGAKWLNDEEKRVLTANIEAENRAKTASPHSIGATLTDRRVWLMCLIYFCFVLGQYGLNFWMPTIVKASGVNGNLNIG
LISAIPYICTFVVMLALGRSADRLRERRWHLVVPAFIAAGGFVAATMATSTTVSIVCLSLAAAGAISCAPLFWSLPTAFL
AGTGAAAGIAWINSVGNLAGFLGPFLVGYLKDFTGTNSAGMYLLAAALVIGSLAVLTVPAKSVNR
>Mature_464_residues
AALPKSGMACRGRISRRPRQQSEEKIMTLQTQAPVVGLHPAQTLEDRAYGKVFWRIVPFLMLCYVVAYLDRVNVGFAKLQ
MSSELGLSEAAYGIGAGIFFIGYFLFEVPSNIIMNKVGARVWIARIMVTWGIISAALMFTSSETVFYVLRFLLGVAEAGF
FPGIILYLTAWYPAHRRARIITTFMSAIPISAIFGNPLSGLLMDSFHGTHGLSGWQWMFLIEAIPAILFGVATFFYLDDT
IQGAKWLNDEEKRVLTANIEAENRAKTASPHSIGATLTDRRVWLMCLIYFCFVLGQYGLNFWMPTIVKASGVNGNLNIGL
ISAIPYICTFVVMLALGRSADRLRERRWHLVVPAFIAAGGFVAATMATSTTVSIVCLSLAAAGAISCAPLFWSLPTAFLA
GTGAAAGIAWINSVGNLAGFLGPFLVGYLKDFTGTNSAGMYLLAAALVIGSLAVLTVPAKSVNR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=390, Percent_Identity=21.7948717948718, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI87082071, Length=422, Percent_Identity=39.0995260663507, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI1789152, Length=446, Percent_Identity=25.7847533632287, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789515, Length=441, Percent_Identity=23.1292517006803, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI87082320, Length=415, Percent_Identity=22.4096385542169, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI2367379, Length=424, Percent_Identity=20.5188679245283, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI2367193, Length=263, Percent_Identity=24.3346007604563, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17560030, Length=373, Percent_Identity=23.3243967828418, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321698, Length=390, Percent_Identity=22.0512820512821, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322025, Length=180, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319876, Length=325, Percent_Identity=23.6923076923077, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323032, Length=260, Percent_Identity=26.1538461538462, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6321502, Length=409, Percent_Identity=21.760391198044, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322612, Length=287, Percent_Identity=22.2996515679443, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324410, Length=160, Percent_Identity=22.5, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24584153, Length=355, Percent_Identity=22.5352112676056, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583789, Length=371, Percent_Identity=23.989218328841, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50482; Mature: 50351

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALPKSGMACRGRISRRPRQQSEEKIMTLQTQAPVVGLHPAQTLEDRAYGKVFWRIVPF
CCCCCCCCCHHHHHHHCCCCHHHHHHHEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHH
LMLCYVVAYLDRVNVGFAKLQMSSELGLSEAAYGIGAGIFFIGYFLFEVPSNIIMNKVGA
HHHHHHHHHHHHCCCCHHHEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVWIARIMVTWGIISAALMFTSSETVFYVLRFLLGVAEAGFFPGIILYLTAWYPAHRRAR
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHH
IITTFMSAIPISAIFGNPLSGLLMDSFHGTHGLSGWQWMFLIEAIPAILFGVATFFYLDD
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TIQGAKWLNDEEKRVLTANIEAENRAKTASPHSIGATLTDRRVWLMCLIYFCFVLGQYGL
HHCHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCH
NFWMPTIVKASGVNGNLNIGLISAIPYICTFVVMLALGRSADRLRERRWHLVVPAFIAAG
HHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHEEEHHHHHCC
GFVAATMATSTTVSIVCLSLAAAGAISCAPLFWSLPTAFLAGTGAAAGIAWINSVGNLAG
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FLGPFLVGYLKDFTGTNSAGMYLLAAALVIGSLAVLTVPAKSVNR
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEECHHHCCC
>Mature Secondary Structure 
AALPKSGMACRGRISRRPRQQSEEKIMTLQTQAPVVGLHPAQTLEDRAYGKVFWRIVPF
CCCCCCCCHHHHHHHCCCCHHHHHHHEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHH
LMLCYVVAYLDRVNVGFAKLQMSSELGLSEAAYGIGAGIFFIGYFLFEVPSNIIMNKVGA
HHHHHHHHHHHHCCCCHHHEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVWIARIMVTWGIISAALMFTSSETVFYVLRFLLGVAEAGFFPGIILYLTAWYPAHRRAR
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHH
IITTFMSAIPISAIFGNPLSGLLMDSFHGTHGLSGWQWMFLIEAIPAILFGVATFFYLDD
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TIQGAKWLNDEEKRVLTANIEAENRAKTASPHSIGATLTDRRVWLMCLIYFCFVLGQYGL
HHCHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCH
NFWMPTIVKASGVNGNLNIGLISAIPYICTFVVMLALGRSADRLRERRWHLVVPAFIAAG
HHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHEEEHHHHHCC
GFVAATMATSTTVSIVCLSLAAAGAISCAPLFWSLPTAFLAGTGAAAGIAWINSVGNLAG
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FLGPFLVGYLKDFTGTNSAGMYLLAAALVIGSLAVLTVPAKSVNR
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEECHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]