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The map label for this gene is eutG [H]

Identifier: 116249104

GI number: 116249104

Start: 472485

End: 473642

Strand: Reverse

Name: eutG [H]

Synonym: pRL120439

Alternate gene names: 116249104

Gene position: 473642-472485 (Counterclockwise)

Preceding gene: 116249105

Following gene: 116249103

Centisome position: 54.44

GC content: 61.92

Gene sequence:

>1158_bases
ATGTCCACATTCACATTCGCGACCGTCCCGCAGATCATCGCGGGACCGGGCTGCATCGCAAGGCTTTCGGAGCTGACGAA
AACGCGACTTGGGTCGCGCGTCATGGTGATTTCGGACGAAGGCGTCGTCAAGGCGGGGCTTGTTCAGCCGGCCCTGGCAA
GCCTTGCGGACGGCGGCGTTGAAGTATCGGTCTTCACCGGCGTTGTCGCCGATCCGCCGGAAGCCATCATTCATGCGGCT
GTGGCGCAGGCGATCGGTTTCGGTGCCACGGGTGTGCTGGGCATTGGCGGCGGCTCGTCGCTCGATGTCGCAAAACTTGT
AGCCCTGCTCTGCAAAAGCGGCGAAGCACTCGGCGATATATATGGTGTAGCTAAGGTTCGTGGGCAGCGCCTTCCGCTGG
TACTCGTGCCGACGACGGCAGGCACCGGCTCCGAAGTCACTCCAATTTCCATTGTCACTACGGGTGCACACGAGAAAAAA
GGCGTCGTATCGCCGGTGCTACTGCCGGATGCGGCACTTCTCGACGCGGAGTTGACCCTCGGCCTTCCTCCAGCCGTGAC
GGCTGCAACGGGGATTGACGCCATGGTGCACGCCATCGAGGCTTTTACCTCCGCGAGTGCGAACAACAATCCGGTTTCCC
GTGCCCTAGCCAAGGAGGCTCTTCGGCTACTCGGGGCAAATATCGAGATCGCAGTCATGAAAGGAACCGATCTCGCCGCC
CGGCAGGCGATGCTGCTCGGCGCCATGTTGGCCGGTCAGGCCTTTGCCAATTCGCCGGTCGCTGCCGTCCATGCTCTCGC
CTACCCGATCGGTGGCCGCTATCACGTTGCGCACGGCCTTTCCAACAGTCTGGTCCTGCCGCATGTGCTGCGCTTCAACG
CGATCGCGTGCGGTGATGCCTATGCGGAACTGGCGCCGTGCCTTTTTCCTGACCTTGAGCCCGCCGGTCAGGCTGAGCGG
CTTGCCGGTTTCATCGAAGGACTGGCAATACTGCCTGTGCGCCTCAACCTGCCCGTACGCCTGAGGGATGTCGGAATTCC
CAAGGACGGGCTTCCCCTGCTAGCGGAAAGTGCGATGAAACAGATCCGCCTGCTGGTCAACAATCCGCGCACGGTGTCGC
TGTCGGATGCCGCGAGGATCTACGAAGTCGCTTGGTAA

Upstream 100 bases:

>100_bases
TATCCGACGAACATCGTCAGACGAAAGGATCTTGTCGTCATGCGCCAGCCGCATCACTATCAGCCGCTCGTCAAATGGCA
TCAGTGAGAGACAGGCCAAG

Downstream 100 bases:

>100_bases
CGAGGTGCCTAACGTTAGGATACGGAGCAGCGTACGACACAAGCCAAAACAACCGTATGATCCGGACGCAAGGACTTTTA
AAAACTGTTTTTTCTTTGCG

Product: putative alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MSTFTFATVPQIIAGPGCIARLSELTKTRLGSRVMVISDEGVVKAGLVQPALASLADGGVEVSVFTGVVADPPEAIIHAA
VAQAIGFGATGVLGIGGGSSLDVAKLVALLCKSGEALGDIYGVAKVRGQRLPLVLVPTTAGTGSEVTPISIVTTGAHEKK
GVVSPVLLPDAALLDAELTLGLPPAVTAATGIDAMVHAIEAFTSASANNNPVSRALAKEALRLLGANIEIAVMKGTDLAA
RQAMLLGAMLAGQAFANSPVAAVHALAYPIGGRYHVAHGLSNSLVLPHVLRFNAIACGDAYAELAPCLFPDLEPAGQAER
LAGFIEGLAILPVRLNLPVRLRDVGIPKDGLPLLAESAMKQIRLLVNNPRTVSLSDAARIYEVAW

Sequences:

>Translated_385_residues
MSTFTFATVPQIIAGPGCIARLSELTKTRLGSRVMVISDEGVVKAGLVQPALASLADGGVEVSVFTGVVADPPEAIIHAA
VAQAIGFGATGVLGIGGGSSLDVAKLVALLCKSGEALGDIYGVAKVRGQRLPLVLVPTTAGTGSEVTPISIVTTGAHEKK
GVVSPVLLPDAALLDAELTLGLPPAVTAATGIDAMVHAIEAFTSASANNNPVSRALAKEALRLLGANIEIAVMKGTDLAA
RQAMLLGAMLAGQAFANSPVAAVHALAYPIGGRYHVAHGLSNSLVLPHVLRFNAIACGDAYAELAPCLFPDLEPAGQAER
LAGFIEGLAILPVRLNLPVRLRDVGIPKDGLPLLAESAMKQIRLLVNNPRTVSLSDAARIYEVAW
>Mature_384_residues
STFTFATVPQIIAGPGCIARLSELTKTRLGSRVMVISDEGVVKAGLVQPALASLADGGVEVSVFTGVVADPPEAIIHAAV
AQAIGFGATGVLGIGGGSSLDVAKLVALLCKSGEALGDIYGVAKVRGQRLPLVLVPTTAGTGSEVTPISIVTTGAHEKKG
VVSPVLLPDAALLDAELTLGLPPAVTAATGIDAMVHAIEAFTSASANNNPVSRALAKEALRLLGANIEIAVMKGTDLAAR
QAMLLGAMLAGQAFANSPVAAVHALAYPIGGRYHVAHGLSNSLVLPHVLRFNAIACGDAYAELAPCLFPDLEPAGQAERL
AGFIEGLAILPVRLNLPVRLRDVGIPKDGLPLLAESAMKQIRLLVNNPRTVSLSDAARIYEVAW

Specific function: May act on the acetaldehyde produced from the degradation of ethanolamine [H]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=392, Percent_Identity=29.0816326530612, Blast_Score=107, Evalue=1e-23,
Organism=Escherichia coli, GI87082107, Length=381, Percent_Identity=35.4330708661417, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1789163, Length=374, Percent_Identity=30.4812834224599, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI48994951, Length=355, Percent_Identity=30.7042253521127, Blast_Score=178, Evalue=6e-46,
Organism=Escherichia coli, GI1787493, Length=349, Percent_Identity=30.3724928366762, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1789386, Length=395, Percent_Identity=25.0632911392405, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17537053, Length=395, Percent_Identity=26.3291139240506, Blast_Score=123, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321181, Length=369, Percent_Identity=32.520325203252, Blast_Score=186, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24657991, Length=408, Percent_Identity=30.1470588235294, Blast_Score=134, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: NA

Molecular weight: Translated: 39342; Mature: 39211

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTFTFATVPQIIAGPGCIARLSELTKTRLGSRVMVISDEGVVKAGLVQPALASLADGGV
CCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEHHHHHHHHHHHCCCCE
EVSVFTGVVADPPEAIIHAAVAQAIGFGATGVLGIGGGSSLDVAKLVALLCKSGEALGDI
EEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHCCCHHHHH
YGVAKVRGQRLPLVLVPTTAGTGSEVTPISIVTTGAHEKKGVVSPVLLPDAALLDAELTL
HHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCEECCCHHHCCCEEEE
GLPPAVTAATGIDAMVHAIEAFTSASANNNPVSRALAKEALRLLGANIEIAVMKGTDLAA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCHHH
RQAMLLGAMLAGQAFANSPVAAVHALAYPIGGRYHVAHGLSNSLVLPHVLRFNAIACGDA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCEECCCH
YAELAPCLFPDLEPAGQAERLAGFIEGLAILPVRLNLPVRLRDVGIPKDGLPLLAESAMK
HHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHHH
QIRLLVNNPRTVSLSDAARIYEVAW
HHHHHCCCCCEEEECCHHHEEEECC
>Mature Secondary Structure 
STFTFATVPQIIAGPGCIARLSELTKTRLGSRVMVISDEGVVKAGLVQPALASLADGGV
CCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEHHHHHHHHHHHCCCCE
EVSVFTGVVADPPEAIIHAAVAQAIGFGATGVLGIGGGSSLDVAKLVALLCKSGEALGDI
EEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHCCCHHHHH
YGVAKVRGQRLPLVLVPTTAGTGSEVTPISIVTTGAHEKKGVVSPVLLPDAALLDAELTL
HHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCEECCCHHHCCCEEEE
GLPPAVTAATGIDAMVHAIEAFTSASANNNPVSRALAKEALRLLGANIEIAVMKGTDLAA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCHHH
RQAMLLGAMLAGQAFANSPVAAVHALAYPIGGRYHVAHGLSNSLVLPHVLRFNAIACGDA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCEECCCH
YAELAPCLFPDLEPAGQAERLAGFIEGLAILPVRLNLPVRLRDVGIPKDGLPLLAESAMK
HHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHHH
QIRLLVNNPRTVSLSDAARIYEVAW
HHHHHCCCCCEEEECCHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]