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The map label for this gene is rhmA [H]

Identifier: 116249080

GI number: 116249080

Start: 448841

End: 449542

Strand: Direct

Name: rhmA [H]

Synonym: pRL120414

Alternate gene names: 116249080

Gene position: 448841-449542 (Clockwise)

Preceding gene: 116249079

Following gene: 116249082

Centisome position: 51.59

GC content: 62.82

Gene sequence:

>702_bases
ATGAACGGAGCCAAATTGCGCGCCCGGCTGTTGGCCGGCGAGGCGATCACCATGTATACGCCGCACCACTCCTCGTCGGG
GCTGGCAGCCCGACTGGTGGAGCTCGGCGCCGATTCCGTCTTCGTCGACTGCGAACACGGAACCTGGAGCTTCGACGATG
TGCGCATGACCGCACAGATTGTCCGTTCTGTCGGCGGAGCGGCGATCGTCCGGCCACATTCGCACGAACGCCCGATCATC
ATCAGATATCTGAATGCGGGAGCCGACGGCATCATGGTCCCGATGGTGGACACGGCCGAACAGGCGCGCGCCGTCGTCGA
TGCCGTCCGTTACGCTCTTCCGTCCGACTTCGACAAGCGCCTGGTGGTGGCGATGATCGAGACAGTGGATGCCATCGACA
ATCTCGACCAGATGCTGAAGGTCGACGGCATCGACGTCTTCTTCATCGGACCTGGCGATCTCTCACAGAATATGGGCTAT
CCGCCGGCTCCACCCTTCGGCGAGCCGCGTCCTGAAGCTGTCATGGAGAAGGTCGCGCTCGCCGTCGACAAGATCCGCGC
AGCAGGCAGGGTTGCAGGCACGCTGGCCACCGCCGATGAACTGCCTCATTGGCTGCAGAAGGGTGTTCAGTTCTTTTACA
TCCACACCGACCCCTTCCTGCGCCGCGGGATTGCCGGCATCAGGCAGACGCTGGCGCGATAG

Upstream 100 bases:

>100_bases
TTCATGCGGGACACGTCAGCGGATATCGAAATTGCGCGTTGGGTCGGTGCGCCGGCCGATACGCCCGATATGCCGAAAAA
ATAGAATTGGGAGGACATTG

Downstream 100 bases:

>100_bases
CAGGCGGGGTAGATTTCCTTCTTCGCTGACGCTGGGCTGCCATGCGGAGGGGCGCTCAATTAATATTAGCTTAGATCGCG
GTTCAGCGCCTGCCCCTCGT

Product: HpcH/HpaI family aldolase

Products: NA

Alternate protein names: KDR aldolase; 2-dehydro-3-deoxyrhamnonate aldolase [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MNGAKLRARLLAGEAITMYTPHHSSSGLAARLVELGADSVFVDCEHGTWSFDDVRMTAQIVRSVGGAAIVRPHSHERPII
IRYLNAGADGIMVPMVDTAEQARAVVDAVRYALPSDFDKRLVVAMIETVDAIDNLDQMLKVDGIDVFFIGPGDLSQNMGY
PPAPPFGEPRPEAVMEKVALAVDKIRAAGRVAGTLATADELPHWLQKGVQFFYIHTDPFLRRGIAGIRQTLAR

Sequences:

>Translated_233_residues
MNGAKLRARLLAGEAITMYTPHHSSSGLAARLVELGADSVFVDCEHGTWSFDDVRMTAQIVRSVGGAAIVRPHSHERPII
IRYLNAGADGIMVPMVDTAEQARAVVDAVRYALPSDFDKRLVVAMIETVDAIDNLDQMLKVDGIDVFFIGPGDLSQNMGY
PPAPPFGEPRPEAVMEKVALAVDKIRAAGRVAGTLATADELPHWLQKGVQFFYIHTDPFLRRGIAGIRQTLAR
>Mature_233_residues
MNGAKLRARLLAGEAITMYTPHHSSSGLAARLVELGADSVFVDCEHGTWSFDDVRMTAQIVRSVGGAAIVRPHSHERPII
IRYLNAGADGIMVPMVDTAEQARAVVDAVRYALPSDFDKRLVVAMIETVDAIDNLDQMLKVDGIDVFFIGPGDLSQNMGY
PPAPPFGEPRPEAVMEKVALAVDKIRAAGRVAGTLATADELPHWLQKGVQFFYIHTDPFLRRGIAGIRQTLAR

Specific function: Catalyzes the reversible retro-aldol cleavage of 2-keto- 3-deoxy-L-rhamnonate (KDR) to pyruvate and lactaldehyde [H]

COG id: COG3836

COG function: function code G; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family. KDR aldolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788578, Length=239, Percent_Identity=31.7991631799163, Blast_Score=111, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: NA

Molecular weight: Translated: 25358; Mature: 25358

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGAKLRARLLAGEAITMYTPHHSSSGLAARLVELGADSVFVDCEHGTWSFDDVRMTAQI
CCCHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHH
VRSVGGAAIVRPHSHERPIIIRYLNAGADGIMVPMVDTAEQARAVVDAVRYALPSDFDKR
HHHCCCEEEECCCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHH
LVVAMIETVDAIDNLDQMLKVDGIDVFFIGPGDLSQNMGYPPAPPFGEPRPEAVMEKVAL
HHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AVDKIRAAGRVAGTLATADELPHWLQKGVQFFYIHTDPFLRRGIAGIRQTLAR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNGAKLRARLLAGEAITMYTPHHSSSGLAARLVELGADSVFVDCEHGTWSFDDVRMTAQI
CCCHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHH
VRSVGGAAIVRPHSHERPIIIRYLNAGADGIMVPMVDTAEQARAVVDAVRYALPSDFDKR
HHHCCCEEEECCCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHH
LVVAMIETVDAIDNLDQMLKVDGIDVFFIGPGDLSQNMGYPPAPPFGEPRPEAVMEKVAL
HHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
AVDKIRAAGRVAGTLATADELPHWLQKGVQFFYIHTDPFLRRGIAGIRQTLAR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA