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The map label for this gene is nanR [H]

Identifier: 116249063

GI number: 116249063

Start: 430285

End: 431043

Strand: Direct

Name: nanR [H]

Synonym: pRL120397

Alternate gene names: 116249063

Gene position: 430285-431043 (Clockwise)

Preceding gene: 116249041

Following gene: 116249064

Centisome position: 49.46

GC content: 57.84

Gene sequence:

>759_bases
TTGTTCTCGACACGGAAACTGTTAGGAGAAAACATTTTGAGCCAGCGAGATGTGATGACCCAACCCCTCGAACAAATCGT
CCGCCGGAAACTCTCTGACGAAGTGTTTGATCGACTTGAGCGAATGATCACCTCGGGCGAGCTTCAGCCCGGCGACGAAA
TGCCGTCCGAGCGGGTGCTGATGGAACGCTTCGGCGTCGGCCGGCCGGCGATCAGGGAGGCGATGCAGTCCCTTGCCAAT
AAAGGTCTTGTCAGCATTTCGCATGGCGAGCGGGCGAAGGTCCTCAGGCTGACGGCAAAGTCGATATTCCGTCAGGTCGA
TCTCACCGCCAAGATCATGCTGTCGCAATCGTCGGACTCGTTGGAATATCTGAAGAGCGCGCGCATCTTCTTCGAGCGGG
GCATGGCGCGCGAGGCGGCGCAGCGGGCCTCCGCAAATGATATCGCTGACCTCAGGAATGTCATCGAACGCCAGCGCATG
TCGCTTGGCCGGGCAGAAGAGTTCATCGACGCGGACATGGAATTCCACACCCGCATCGCGCAGATATCAGGCAACCCGAT
CTACGTCGCCGTCAGCGAAGCAATGCTTGCCTGGCTGAAGGAATATCATACCGAGATGCTGATCTGGACCGGCAAGGAAA
AATTCACGCTCGCCGAACACGACGAGATCGTCGACCGCCTTGAAGCAAACGACGTGGATGGCTCGGAAACGGCACTCCTC
AAGCATCTCGAGCGGTCGCGAGCGCTTTACGCGAAGTAA

Upstream 100 bases:

>100_bases
CCACGCAGATTGCCATGGCGTCAACTCGTGATCTGGTATAATGAGTATTCCAACTTATGAAAAGTAGAATCTTCGGATCC
GCAAAATTTCGCCGACAGCT

Downstream 100 bases:

>100_bases
TATTCACGAACTCGGCGACCACCCTTGGCTGGCATACCTGGCCGTCGCTCGTCTCCTGACCCGTCTCACCCTTGATCCTC
GGCCGCGCGCGCATTTGCCG

Product: transcriptional regulator NanR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MFSTRKLLGENILSQRDVMTQPLEQIVRRKLSDEVFDRLERMITSGELQPGDEMPSERVLMERFGVGRPAIREAMQSLAN
KGLVSISHGERAKVLRLTAKSIFRQVDLTAKIMLSQSSDSLEYLKSARIFFERGMAREAAQRASANDIADLRNVIERQRM
SLGRAEEFIDADMEFHTRIAQISGNPIYVAVSEAMLAWLKEYHTEMLIWTGKEKFTLAEHDEIVDRLEANDVDGSETALL
KHLERSRALYAK

Sequences:

>Translated_252_residues
MFSTRKLLGENILSQRDVMTQPLEQIVRRKLSDEVFDRLERMITSGELQPGDEMPSERVLMERFGVGRPAIREAMQSLAN
KGLVSISHGERAKVLRLTAKSIFRQVDLTAKIMLSQSSDSLEYLKSARIFFERGMAREAAQRASANDIADLRNVIERQRM
SLGRAEEFIDADMEFHTRIAQISGNPIYVAVSEAMLAWLKEYHTEMLIWTGKEKFTLAEHDEIVDRLEANDVDGSETALL
KHLERSRALYAK
>Mature_252_residues
MFSTRKLLGENILSQRDVMTQPLEQIVRRKLSDEVFDRLERMITSGELQPGDEMPSERVLMERFGVGRPAIREAMQSLAN
KGLVSISHGERAKVLRLTAKSIFRQVDLTAKIMLSQSSDSLEYLKSARIFFERGMAREAAQRASANDIADLRNVIERQRM
SLGRAEEFIDADMEFHTRIAQISGNPIYVAVSEAMLAWLKEYHTEMLIWTGKEKFTLAEHDEIVDRLEANDVDGSETALL
KHLERSRALYAK

Specific function: Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789621, Length=237, Percent_Identity=36.7088607594937, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI48994961, Length=211, Percent_Identity=27.9620853080569, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790032, Length=224, Percent_Identity=26.3392857142857, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI48994955, Length=221, Percent_Identity=25.7918552036199, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789353, Length=171, Percent_Identity=30.4093567251462, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 28788; Mature: 28788

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSTRKLLGENILSQRDVMTQPLEQIVRRKLSDEVFDRLERMITSGELQPGDEMPSERVL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
MERFGVGRPAIREAMQSLANKGLVSISHGERAKVLRLTAKSIFRQVDLTAKIMLSQSSDS
HHHHCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LEYLKSARIFFERGMAREAAQRASANDIADLRNVIERQRMSLGRAEEFIDADMEFHTRIA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
QISGNPIYVAVSEAMLAWLKEYHTEMLIWTGKEKFTLAEHDEIVDRLEANDVDGSETALL
HCCCCEEEEEHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
KHLERSRALYAK
HHHHHHHHHCCC
>Mature Secondary Structure
MFSTRKLLGENILSQRDVMTQPLEQIVRRKLSDEVFDRLERMITSGELQPGDEMPSERVL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
MERFGVGRPAIREAMQSLANKGLVSISHGERAKVLRLTAKSIFRQVDLTAKIMLSQSSDS
HHHHCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LEYLKSARIFFERGMAREAAQRASANDIADLRNVIERQRMSLGRAEEFIDADMEFHTRIA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
QISGNPIYVAVSEAMLAWLKEYHTEMLIWTGKEKFTLAEHDEIVDRLEANDVDGSETALL
HCCCCEEEEEHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
KHLERSRALYAK
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA