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The map label for this gene is dapA [H]

Identifier: 116248997

GI number: 116248997

Start: 352573

End: 353490

Strand: Direct

Name: dapA [H]

Synonym: pRL120328

Alternate gene names: 116248997

Gene position: 352573-353490 (Clockwise)

Preceding gene: 116248996

Following gene: 116248998

Centisome position: 40.52

GC content: 62.96

Gene sequence:

>918_bases
ATGACCAAATTCAAGGGTGTCGTCCCTCCCGTCGTAACGCCGCTCAATCCGGATCTCACCGTCGATTACCCATCCTATAC
ACGCGTGCTCGAACATCTGATCGATGCCGGCTGCCATGGCGTATTCGTGCTCGGCTCGACGAGTGAGGTGATCTTCCATG
ACGAAAAGACCCGGCGGGACGTCATCGAACATTCGGCCAAGGTGGTGAATGGCCGGGTGCCGTTGATCGTCGGCGTCATC
GATCCGACCACGGATCGCGTCATCGCCCATGCGAAGGTCGCAAAGGCCGCCGGCGCCGATGCGGTCGTGGTGACGGCCCC
ATTCTATACTGTCACCAGCCAGTCCGAGATACTCGATCACTTCCGTTATATCCGCGACGCGGTGGACATTCCGCTGATCG
CCTACGACATTCCCGTCTGCGTTCACGTCAAGCTGCAGCGCCAGACCGTGGTCACGCTCGCCAGGGAAGGCGCGATTATT
GGTCTCAAGGATTCCAGCGGCGACGACGGCAACTTCCGCTATGCGCTCCTCGATCTTGCCGAACACAAGAACGTCTTCCT
GATGACCGGCTCCGAGATCGTCGTCGACACCGCCCTGCTGATGGGCGCCCATGGCGTCGTTCCCGGTATCGCCAATGTCG
ATCCGCACGGCTATGTCCGCCTTTGGGATGCTGCCCAGCGTGGCGACTGGGTCGCCGCAAGGAAGGAGCAGGAGCGCCTC
TGCCGCCTGTTCGAAATCGTCTGGGTCGCGCAGGGCCGCGTCAGCGGCGGCGCAGCCGGCATCGGCGCCTTCAAGGCGGC
GATGCGCAGCCTCGGCATCATCGATTCCGCCGTCATGCCGCGGCCGCGTGCCGCCCTCAACGATGCCGAAACGGCGCGGA
TCGACGAGATCCTGCGTGCAACCGGCCTGCTGAACTGA

Upstream 100 bases:

>100_bases
GCTCATCCTTGCCGTCCTGGCGATCAACTTCATTGGCGATGGCCTCAGAGATGCCTTCGACCCACGTGCCGAACTGAACT
GACAATCGAAAGAAGCGAAA

Downstream 100 bases:

>100_bases
GCCGGCTAATGGAACAGATCGCCGAACCCGTGCTCGACATCAAGGGATTGCGAACGGTCTTCCGCATCCGCGGCGGTGAG
ATCACGGCGGTCAACAATAT

Product: putative dihydropicolinate synthase family protein

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MTKFKGVVPPVVTPLNPDLTVDYPSYTRVLEHLIDAGCHGVFVLGSTSEVIFHDEKTRRDVIEHSAKVVNGRVPLIVGVI
DPTTDRVIAHAKVAKAAGADAVVVTAPFYTVTSQSEILDHFRYIRDAVDIPLIAYDIPVCVHVKLQRQTVVTLAREGAII
GLKDSSGDDGNFRYALLDLAEHKNVFLMTGSEIVVDTALLMGAHGVVPGIANVDPHGYVRLWDAAQRGDWVAARKEQERL
CRLFEIVWVAQGRVSGGAAGIGAFKAAMRSLGIIDSAVMPRPRAALNDAETARIDEILRATGLLN

Sequences:

>Translated_305_residues
MTKFKGVVPPVVTPLNPDLTVDYPSYTRVLEHLIDAGCHGVFVLGSTSEVIFHDEKTRRDVIEHSAKVVNGRVPLIVGVI
DPTTDRVIAHAKVAKAAGADAVVVTAPFYTVTSQSEILDHFRYIRDAVDIPLIAYDIPVCVHVKLQRQTVVTLAREGAII
GLKDSSGDDGNFRYALLDLAEHKNVFLMTGSEIVVDTALLMGAHGVVPGIANVDPHGYVRLWDAAQRGDWVAARKEQERL
CRLFEIVWVAQGRVSGGAAGIGAFKAAMRSLGIIDSAVMPRPRAALNDAETARIDEILRATGLLN
>Mature_304_residues
TKFKGVVPPVVTPLNPDLTVDYPSYTRVLEHLIDAGCHGVFVLGSTSEVIFHDEKTRRDVIEHSAKVVNGRVPLIVGVID
PTTDRVIAHAKVAKAAGADAVVVTAPFYTVTSQSEILDHFRYIRDAVDIPLIAYDIPVCVHVKLQRQTVVTLAREGAIIG
LKDSSGDDGNFRYALLDLAEHKNVFLMTGSEIVVDTALLMGAHGVVPGIANVDPHGYVRLWDAAQRGDWVAARKEQERLC
RLFEIVWVAQGRVSGGAAGIGAFKAAMRSLGIIDSAVMPRPRAALNDAETARIDEILRATGLLN

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=238, Percent_Identity=28.9915966386555, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI87082415, Length=307, Percent_Identity=28.0130293159609, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789620, Length=251, Percent_Identity=31.8725099601594, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786463, Length=245, Percent_Identity=27.7551020408163, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788823, Length=303, Percent_Identity=24.4224422442244, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 33015; Mature: 32884

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00445 FGGY_KINASES_2 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKFKGVVPPVVTPLNPDLTVDYPSYTRVLEHLIDAGCHGVFVLGSTSEVIFHDEKTRRD
CCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCEEEEECCCCEEEEECCHHHHH
VIEHSAKVVNGRVPLIVGVIDPTTDRVIAHAKVAKAAGADAVVVTAPFYTVTSQSEILDH
HHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECEEEECCHHHHHHH
FRYIRDAVDIPLIAYDIPVCVHVKLQRQTVVTLAREGAIIGLKDSSGDDGNFRYALLDLA
HHHHHHHCCCCEEEEECCEEEEEEECHHHEEEHHHCCCEEEEECCCCCCCCEEEEEEEHH
EHKNVFLMTGSEIVVDTALLMGAHGVVPGIANVDPHGYVRLWDAAQRGDWVAARKEQERL
CCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCEEHHHHHHHHH
CRLFEIVWVAQGRVSGGAAGIGAFKAAMRSLGIIDSAVMPRPRAALNDAETARIDEILRA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCCHHCCCCHHHHHHHHHHH
TGLLN
HCCCC
>Mature Secondary Structure 
TKFKGVVPPVVTPLNPDLTVDYPSYTRVLEHLIDAGCHGVFVLGSTSEVIFHDEKTRRD
CCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCEEEEECCCCEEEEECCHHHHH
VIEHSAKVVNGRVPLIVGVIDPTTDRVIAHAKVAKAAGADAVVVTAPFYTVTSQSEILDH
HHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECEEEECCHHHHHHH
FRYIRDAVDIPLIAYDIPVCVHVKLQRQTVVTLAREGAIIGLKDSSGDDGNFRYALLDLA
HHHHHHHCCCCEEEEECCEEEEEEECHHHEEEHHHCCCEEEEECCCCCCCCEEEEEEEHH
EHKNVFLMTGSEIVVDTALLMGAHGVVPGIANVDPHGYVRLWDAAQRGDWVAARKEQERL
CCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCEEHHHHHHHHH
CRLFEIVWVAQGRVSGGAAGIGAFKAAMRSLGIIDSAVMPRPRAALNDAETARIDEILRA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCCHHCCCCHHHHHHHHHHH
TGLLN
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]