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The map label for this gene is fhuA [H]

Identifier: 116248991

GI number: 116248991

Start: 344272

End: 346452

Strand: Reverse

Name: fhuA [H]

Synonym: pRL120322

Alternate gene names: 116248991

Gene position: 346452-344272 (Counterclockwise)

Preceding gene: 116249001

Following gene: 116248990

Centisome position: 39.82

GC content: 58.46

Gene sequence:

>2181_bases
ATGGCGCGTGTTTTTTTGAATGTTTCTAATAATGTATCGCGAATTTATAGAGATAGCCTATTTGTCACGACAGCGATCGT
CCTGATCGGCATTGCAGCATCGCCGGCCTCAGCCCAGAGCGCATCCGCAGATGCCGGCGCGACAGCGCTGGAACCGATCG
TCATTCAAGGCGCATCCTCTGATAGCAAGACGGACCGGACGTCCGTTGCCGCCAAGAACAGTTCGGCCGCGACCAAGGTC
AACACGCCGCTCGTCGAAACGCCGCGTTCGGTCTCGGTGACCACCGAGAAGGAAATCGAGCAGCGTGGCGCCCAGAGCAT
CATCGAGGCCGTGCGCTACTCGGCCGGCGTGACGACAGGGCCGAACGGCTTCGATCCGCGCTTCGACCAGATCTACATCC
GCGGCTTTAACGTTACGACGGTCGGTGACTACCGTGACAGCTTGCGCCAGCCCTACATCAATTACGGCATGTTCCGCACC
GATCCCTATCAACTGCAGCGCGTCGAGGTGATCAAGGGGCCGGTATCCGTGCTCTACGGCTCGGGATCGCCGGGCGGTCT
CGTCAACAAGATATCGAAGCTTCCGACCGAAGAGCCGATCCGCGAGGTGGGTATTTCATACAGCACCAAGGATCGGGCTC
AGGCGATGTTCGATTTCGGCGGGCCGATCAGCGAAGACAATGACGATTTCCTCTATCGCATCGTCGGCCTTGCCCGCCGT
GGCGACACCAATTTCGATATTGCCGACGACCGCTATTTCCTGGCGCCGTCCTTCACCTGGAAACCGGACGAGGGCACGAC
CTTCACGGTGTACGGTCTGGCGCAGGCCGACGAGACCGACTCCAACGTCGGCGCGATCACGACTCTGGACGGCAGAATAC
TCGACATCAGGCAGAGCGATCCCGACTACGACTACCAGAAGGTCAAGCAGCAGCAGGTCGGCTATCAGTTCGAGCATGAA
TTCGACAATGGCCTGACGTTCCGGCAGAACCTGCGTTACTCGCATCTCGATCTCAGGGCGCGCTACCTCGGCGTTTCCAG
CTGGACCGGGACCGTCGCACATCGCAACGCAAGTTCGATCCGGGACGAGATGAACGTCTTCCAGGTCGACAACCAGCTCG
AGGCGAAGTTCGATACAGGCCCGCTTGCCCATACGATGCTGTTCGGGCTCGACTACACCAATCTCCAATCCAATTGGGGC
TACGGCATTGGCGCCGTCAACTCGGCATTCGATTTCGATATCGCCAATCCGACCTATGGCGTCTCGGGCGCAACGCCGGC
CTATAACTTCATCGTTGCCGATGCCGACATGCGACAGGTCGGTGTTTACGCCATGGATCAGATCGAGGCCGGAAACTGGC
GCTTTAATCTCGGCGGCCGCCAGACCTGGGTGAACCAGACGCGAGATACGACCTACCCCTCCTTCGGGTCGAACGAATCG
GAAGACGTCAACAAGAATGCGTTCTCCTGGCAGGCCGGCGCGCTTTATCTCTTCGACAACGGCATCGCGCCCTTCGTCTC
TTACGCAACTTCGTTTGACCCGGTGACCAACCGGTCGACATCCGGCAAGATTCTTGAGCCGACAGAGGGTGAACAATACG
AACTCGGCGTAAAATACCAGCCGCCAGGGACAGATATCCTGCTGTCGGCGGTCGCCTATCATATCGTCGAACAGAACAAG
CCAGTGCTGGTCAATCCGGTAACCCTTGCCTATGACTCGCTCGGCGAGGTGACGGGAAAAGGCATCGAGCTTGAAGCCCG
CGCGGCAGTCGCCGATGGCCTGGATCTCATTGCAGCCTACACCTACAATCATTCCGAGGTGACCGGAGGCAACAACGAGG
GCAATACGCCAGCCGTGACGCCGTCACATGTCGCAAGCCTCTGGGCCAACTATACATTCCAGGAAACCAACCCCTTCAAC
GGCCTGTCGGTCGGCGCGGGTGTCCGTTATGTCAGCGAGAATTGGACAGATACAGCCAATACCTCGAAGAATCCCTCGAG
CTTCTACATCGATGCATCCGCCGCTTATGATTTCGGCGCGGTCGACAAGAAATATGAGGGCCTGACGGCCGCCTTCAATA
TCCGCAACATTGCCGACGAACGCGACACTGTCTGCAACGAAGGCTTCTGCTATCTCGGCCAGGGCCGCAACATGACCGGC
ACCCTGAAATACCGGTGGTAA

Upstream 100 bases:

>100_bases
ATTTTATCGATTAAAAGATGACTAAAATAATCATCTTATGTTGACAGAGCCAATTTCGCTCCATAGGTTCCGCCCGCATC
CGTGGCGTAGGGACCAAGCA

Downstream 100 bases:

>100_bases
GGCACGGCAATGGAGACAACCGGGGCGTTTCAGCGCCCGACCTTGATCGCTGACCATCCTGTCGCCCACCAGGCCGTCGA
CCTCGACGGTCTGGTGGGCG

Product: outer membrane siderophore receptor precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 726; Mature: 725

Protein sequence:

>726_residues
MARVFLNVSNNVSRIYRDSLFVTTAIVLIGIAASPASAQSASADAGATALEPIVIQGASSDSKTDRTSVAAKNSSAATKV
NTPLVETPRSVSVTTEKEIEQRGAQSIIEAVRYSAGVTTGPNGFDPRFDQIYIRGFNVTTVGDYRDSLRQPYINYGMFRT
DPYQLQRVEVIKGPVSVLYGSGSPGGLVNKISKLPTEEPIREVGISYSTKDRAQAMFDFGGPISEDNDDFLYRIVGLARR
GDTNFDIADDRYFLAPSFTWKPDEGTTFTVYGLAQADETDSNVGAITTLDGRILDIRQSDPDYDYQKVKQQQVGYQFEHE
FDNGLTFRQNLRYSHLDLRARYLGVSSWTGTVAHRNASSIRDEMNVFQVDNQLEAKFDTGPLAHTMLFGLDYTNLQSNWG
YGIGAVNSAFDFDIANPTYGVSGATPAYNFIVADADMRQVGVYAMDQIEAGNWRFNLGGRQTWVNQTRDTTYPSFGSNES
EDVNKNAFSWQAGALYLFDNGIAPFVSYATSFDPVTNRSTSGKILEPTEGEQYELGVKYQPPGTDILLSAVAYHIVEQNK
PVLVNPVTLAYDSLGEVTGKGIELEARAAVADGLDLIAAYTYNHSEVTGGNNEGNTPAVTPSHVASLWANYTFQETNPFN
GLSVGAGVRYVSENWTDTANTSKNPSSFYIDASAAYDFGAVDKKYEGLTAAFNIRNIADERDTVCNEGFCYLGQGRNMTG
TLKYRW

Sequences:

>Translated_726_residues
MARVFLNVSNNVSRIYRDSLFVTTAIVLIGIAASPASAQSASADAGATALEPIVIQGASSDSKTDRTSVAAKNSSAATKV
NTPLVETPRSVSVTTEKEIEQRGAQSIIEAVRYSAGVTTGPNGFDPRFDQIYIRGFNVTTVGDYRDSLRQPYINYGMFRT
DPYQLQRVEVIKGPVSVLYGSGSPGGLVNKISKLPTEEPIREVGISYSTKDRAQAMFDFGGPISEDNDDFLYRIVGLARR
GDTNFDIADDRYFLAPSFTWKPDEGTTFTVYGLAQADETDSNVGAITTLDGRILDIRQSDPDYDYQKVKQQQVGYQFEHE
FDNGLTFRQNLRYSHLDLRARYLGVSSWTGTVAHRNASSIRDEMNVFQVDNQLEAKFDTGPLAHTMLFGLDYTNLQSNWG
YGIGAVNSAFDFDIANPTYGVSGATPAYNFIVADADMRQVGVYAMDQIEAGNWRFNLGGRQTWVNQTRDTTYPSFGSNES
EDVNKNAFSWQAGALYLFDNGIAPFVSYATSFDPVTNRSTSGKILEPTEGEQYELGVKYQPPGTDILLSAVAYHIVEQNK
PVLVNPVTLAYDSLGEVTGKGIELEARAAVADGLDLIAAYTYNHSEVTGGNNEGNTPAVTPSHVASLWANYTFQETNPFN
GLSVGAGVRYVSENWTDTANTSKNPSSFYIDASAAYDFGAVDKKYEGLTAAFNIRNIADERDTVCNEGFCYLGQGRNMTG
TLKYRW
>Mature_725_residues
ARVFLNVSNNVSRIYRDSLFVTTAIVLIGIAASPASAQSASADAGATALEPIVIQGASSDSKTDRTSVAAKNSSAATKVN
TPLVETPRSVSVTTEKEIEQRGAQSIIEAVRYSAGVTTGPNGFDPRFDQIYIRGFNVTTVGDYRDSLRQPYINYGMFRTD
PYQLQRVEVIKGPVSVLYGSGSPGGLVNKISKLPTEEPIREVGISYSTKDRAQAMFDFGGPISEDNDDFLYRIVGLARRG
DTNFDIADDRYFLAPSFTWKPDEGTTFTVYGLAQADETDSNVGAITTLDGRILDIRQSDPDYDYQKVKQQQVGYQFEHEF
DNGLTFRQNLRYSHLDLRARYLGVSSWTGTVAHRNASSIRDEMNVFQVDNQLEAKFDTGPLAHTMLFGLDYTNLQSNWGY
GIGAVNSAFDFDIANPTYGVSGATPAYNFIVADADMRQVGVYAMDQIEAGNWRFNLGGRQTWVNQTRDTTYPSFGSNESE
DVNKNAFSWQAGALYLFDNGIAPFVSYATSFDPVTNRSTSGKILEPTEGEQYELGVKYQPPGTDILLSAVAYHIVEQNKP
VLVNPVTLAYDSLGEVTGKGIELEARAAVADGLDLIAAYTYNHSEVTGGNNEGNTPAVTPSHVASLWANYTFQETNPFNG
LSVGAGVRYVSENWTDTANTSKNPSSFYIDASAAYDFGAVDKKYEGLTAAFNIRNIADERDTVCNEGFCYLGQGRNMTGT
LKYRW

Specific function: Involved in the initial step of iron uptake by binding chrysobactin, an iron chelatin siderophore that allows the bacteria to extract iron from the environment [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=756, Percent_Identity=32.2751322751323, Blast_Score=341, Evalue=8e-95,
Organism=Escherichia coli, GI1787024, Length=712, Percent_Identity=23.5955056179775, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1787344, Length=791, Percent_Identity=21.4917825537295, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1790743, Length=681, Percent_Identity=22.7606461086637, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 79590; Mature: 79459

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVFLNVSNNVSRIYRDSLFVTTAIVLIGIAASPASAQSASADAGATALEPIVIQGASS
CEEEEEECCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCEEEECCCC
DSKTDRTSVAAKNSSAATKVNTPLVETPRSVSVTTEKEIEQRGAQSIIEAVRYSAGVTTG
CCCCCHHHEEECCCCCCEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCC
PNGFDPRFDQIYIRGFNVTTVGDYRDSLRQPYINYGMFRTDPYQLQRVEVIKGPVSVLYG
CCCCCCCCCEEEEEEEEEEEECHHHHHHCCCHHHCCCEECCHHHEEEEEEECCCEEEEEC
SGSPGGLVNKISKLPTEEPIREVGISYSTKDRAQAMFDFGGPISEDNDDFLYRIVGLARR
CCCCCHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHC
GDTNFDIADDRYFLAPSFTWKPDEGTTFTVYGLAQADETDSNVGAITTLDGRILDIRQSD
CCCCCEECCCCEEECCCCEECCCCCCEEEEEEEEECCCCCCCCCEEEEECCEEEEEECCC
PDYDYQKVKQQQVGYQFEHEFDNGLTFRQNLRYSHLDLRARYLGVSSWTGTVAHRNASSI
CCCHHHHHHHHHCCCEEEECCCCCCEEHHCCCCCCEEEEEEEEECCCCCCCEECCCHHHH
RDEMNVFQVDNQLEAKFDTGPLAHTMLFGLDYTNLQSNWGYGIGAVNSAFDFDIANPTYG
HHHHHEEEECCCCEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCC
VSGATPAYNFIVADADMRQVGVYAMDQIEAGNWRFNLGGRQTWVNQTRDTTYPSFGSNES
CCCCCCCEEEEEECCCHHHHCEEEEEEECCCCEEEECCCCHHHCCCCCCCCCCCCCCCCC
EDVNKNAFSWQAGALYLFDNGIAPFVSYATSFDPVTNRSTSGKILEPTEGEQYELGVKYQ
CCCCCCCEEECCCEEEEEECCCHHHHHHHCCCCCCCCCCCCCCEECCCCCCEEEEEEEEC
PPGTDILLSAVAYHIVEQNKPVLVNPVTLAYDSLGEVTGKGIELEARAAVADGLDLIAAY
CCCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHCCCCEEEEEHHHHHCCCEEEEEE
TYNHSEVTGGNNEGNTPAVTPSHVASLWANYTFQETNPFNGLSVGAGVRYVSENWTDTAN
EECCCEECCCCCCCCCCCCCHHHHHHHHHCCEEECCCCCCCEECCCCEEEECCCCCCCCC
TSKNPSSFYIDASAAYDFGAVDKKYEGLTAAFNIRNIADERDTVCNEGFCYLGQGRNMTG
CCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEHHHHCCHHHHHHCCCCEEEECCCCCEE
TLKYRW
EEEECC
>Mature Secondary Structure 
ARVFLNVSNNVSRIYRDSLFVTTAIVLIGIAASPASAQSASADAGATALEPIVIQGASS
EEEEEECCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCEEEECCCC
DSKTDRTSVAAKNSSAATKVNTPLVETPRSVSVTTEKEIEQRGAQSIIEAVRYSAGVTTG
CCCCCHHHEEECCCCCCEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCC
PNGFDPRFDQIYIRGFNVTTVGDYRDSLRQPYINYGMFRTDPYQLQRVEVIKGPVSVLYG
CCCCCCCCCEEEEEEEEEEEECHHHHHHCCCHHHCCCEECCHHHEEEEEEECCCEEEEEC
SGSPGGLVNKISKLPTEEPIREVGISYSTKDRAQAMFDFGGPISEDNDDFLYRIVGLARR
CCCCCHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHC
GDTNFDIADDRYFLAPSFTWKPDEGTTFTVYGLAQADETDSNVGAITTLDGRILDIRQSD
CCCCCEECCCCEEECCCCEECCCCCCEEEEEEEEECCCCCCCCCEEEEECCEEEEEECCC
PDYDYQKVKQQQVGYQFEHEFDNGLTFRQNLRYSHLDLRARYLGVSSWTGTVAHRNASSI
CCCHHHHHHHHHCCCEEEECCCCCCEEHHCCCCCCEEEEEEEEECCCCCCCEECCCHHHH
RDEMNVFQVDNQLEAKFDTGPLAHTMLFGLDYTNLQSNWGYGIGAVNSAFDFDIANPTYG
HHHHHEEEECCCCEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCC
VSGATPAYNFIVADADMRQVGVYAMDQIEAGNWRFNLGGRQTWVNQTRDTTYPSFGSNES
CCCCCCCEEEEEECCCHHHHCEEEEEEECCCCEEEECCCCHHHCCCCCCCCCCCCCCCCC
EDVNKNAFSWQAGALYLFDNGIAPFVSYATSFDPVTNRSTSGKILEPTEGEQYELGVKYQ
CCCCCCCEEECCCEEEEEECCCHHHHHHHCCCCCCCCCCCCCCEECCCCCCEEEEEEEEC
PPGTDILLSAVAYHIVEQNKPVLVNPVTLAYDSLGEVTGKGIELEARAAVADGLDLIAAY
CCCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHCCCCEEEEEHHHHHCCCEEEEEE
TYNHSEVTGGNNEGNTPAVTPSHVASLWANYTFQETNPFNGLSVGAGVRYVSENWTDTAN
EECCCEECCCCCCCCCCCCCHHHHHHHHHCCEEECCCCCCCEECCCCEEEECCCCCCCCC
TSKNPSSFYIDASAAYDFGAVDKKYEGLTAAFNIRNIADERDTVCNEGFCYLGQGRNMTG
CCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEHHHHCCHHHHHHCCCCEEEECCCCCEE
TLKYRW
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8576065 [H]