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The map label for this gene is agaZ [H]

Identifier: 116248919

GI number: 116248919

Start: 260276

End: 261574

Strand: Reverse

Name: agaZ [H]

Synonym: pRL120249

Alternate gene names: 116248919

Gene position: 261574-260276 (Counterclockwise)

Preceding gene: 116248920

Following gene: 116248918

Centisome position: 30.07

GC content: 61.2

Gene sequence:

>1299_bases
ATGACGTCGATCGAAGAGAACCGGCAGACCGCGCTGCGAAAGCTTTTCGGTGCCCGAAACCTGCCTTTTCCCCATGGCGT
CACTTCGGTCTGCTCGGCGCATCCGCTGGTTATCGAGGCAGCCGTTCGGCGTGCCGGCATGGAGCACCGGGCGGTCCTCA
TCGAAGCCACCTGCAATCAGGTCAATCAGGAGGGCGGCTATACCGCGATGACGCCGGTGGACTTTCGCCGGTTCATCGAG
GACATCGCCGCAGCGACTGATTTTCCAGCCGAACGCATCATCCTGGGAGGCGATCACCTCGGTCCCAACCCATGGAGAAA
ATTGGCGGCCGAGGAGGCAATGCTGCGCGCCGCGGCTATGGTGACGGCCTATGTCGAGGCAGGGTTTGAAAAGATTCACC
TGGACACGTCGATGGGCTGTGCCGGTGAACCAACGGCCATCGATGACGAATTGACCGCGGCGCGGGCCGCTCGATTGGCA
AAGGCCGCTGAGGAGGCCGCTCTTCGTTCAGGTCGCCGTCCGCCGGTCTATATCATCGGAACCGAGGTGCCGCCTCCAGG
TGGTGCAACGCACGCACTCGAAGAAATCGAAATTACCCGGGCCGATGCGGCGATGAAAACGCTGGCGGTTCACCGGGCGT
CGTTTGCCGAAGCAGGTTTGGCGTCGGCAATGGAGCGGGTCATTGGGATCGTGGTTCAGCCGGGCGTGGAATTTGGCAAC
ACGGACGTGGCGCTCTACAAGCCTGAACGGGCCAAGAGCCTCATTCGTTCGCTGGACGACATGCCGGGCTTGGTTTTCGA
AGCACATTCCACCGACTACCAACCGGCCGAAGCCTTGTCTGCTCTCGTTGACGGCGGCTTTGCAATCCTCAAGGTCGGAC
CAGGGCTGACTTTCGCGCTGCGCGAAGCGCTGTACGGTCTCGATGTGATCGCTGACGTGCTTGCCGGGAGGACGCCACGA
GCCGGACTGGTGACGACCATGGAAAAAATCATGGTCGAGCAGCCGGCAAGCTGGACGGGCCACTATGGCGGCAGTCCCGA
TGAGGAGCGACTGCAAAGGCATTTCAGCTATAGTGATCGAATTCGCTATTACTGGCCGGATCCTCGCGCATCCGCCGCGG
TCGGCGAATTGTTCAGCCGGCTCCCCGATGAAATTCCCGAAACTCTGATCAGCCAATATCTCGGCCGACTCTATTCCGAC
GTGGTGTCAAAGCGGGTCGCTCCGAAGGCCCGCGAACTCTGCCTTGCTGCGGTCGACGCGGTATTGGCGCCATATTCAGC
CGCCACGGCAATCCGATGA

Upstream 100 bases:

>100_bases
TTGTCCTTCCGGCGCTGCAGGTCCTCGGCGAACGCGCCGCGCAGGCTCGGCAAATCGACACTGTCTCTCCCCGTCACCTG
ACGAAGGTTGTGACGCTCGC

Downstream 100 bases:

>100_bases
GCAATCGACAGCCGTGTCAGACGAGCGGCTGCGTCCCGAAGATACCAACATTCAGCCGGAGAACGTTATGGCGTCAGTAA
GTGTGGCGAATGCCCGCAAG

Product: putative tagatose 6-phosphate kinase

Products: ADP; D-tagatose 1,6-bisphosphate

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MTSIEENRQTALRKLFGARNLPFPHGVTSVCSAHPLVIEAAVRRAGMEHRAVLIEATCNQVNQEGGYTAMTPVDFRRFIE
DIAAATDFPAERIILGGDHLGPNPWRKLAAEEAMLRAAAMVTAYVEAGFEKIHLDTSMGCAGEPTAIDDELTAARAARLA
KAAEEAALRSGRRPPVYIIGTEVPPPGGATHALEEIEITRADAAMKTLAVHRASFAEAGLASAMERVIGIVVQPGVEFGN
TDVALYKPERAKSLIRSLDDMPGLVFEAHSTDYQPAEALSALVDGGFAILKVGPGLTFALREALYGLDVIADVLAGRTPR
AGLVTTMEKIMVEQPASWTGHYGGSPDEERLQRHFSYSDRIRYYWPDPRASAAVGELFSRLPDEIPETLISQYLGRLYSD
VVSKRVAPKARELCLAAVDAVLAPYSAATAIR

Sequences:

>Translated_432_residues
MTSIEENRQTALRKLFGARNLPFPHGVTSVCSAHPLVIEAAVRRAGMEHRAVLIEATCNQVNQEGGYTAMTPVDFRRFIE
DIAAATDFPAERIILGGDHLGPNPWRKLAAEEAMLRAAAMVTAYVEAGFEKIHLDTSMGCAGEPTAIDDELTAARAARLA
KAAEEAALRSGRRPPVYIIGTEVPPPGGATHALEEIEITRADAAMKTLAVHRASFAEAGLASAMERVIGIVVQPGVEFGN
TDVALYKPERAKSLIRSLDDMPGLVFEAHSTDYQPAEALSALVDGGFAILKVGPGLTFALREALYGLDVIADVLAGRTPR
AGLVTTMEKIMVEQPASWTGHYGGSPDEERLQRHFSYSDRIRYYWPDPRASAAVGELFSRLPDEIPETLISQYLGRLYSD
VVSKRVAPKARELCLAAVDAVLAPYSAATAIR
>Mature_431_residues
TSIEENRQTALRKLFGARNLPFPHGVTSVCSAHPLVIEAAVRRAGMEHRAVLIEATCNQVNQEGGYTAMTPVDFRRFIED
IAAATDFPAERIILGGDHLGPNPWRKLAAEEAMLRAAAMVTAYVEAGFEKIHLDTSMGCAGEPTAIDDELTAARAARLAK
AAEEAALRSGRRPPVYIIGTEVPPPGGATHALEEIEITRADAAMKTLAVHRASFAEAGLASAMERVIGIVVQPGVEFGNT
DVALYKPERAKSLIRSLDDMPGLVFEAHSTDYQPAEALSALVDGGFAILKVGPGLTFALREALYGLDVIADVLAGRTPRA
GLVTTMEKIMVEQPASWTGHYGGSPDEERLQRHFSYSDRIRYYWPDPRASAAVGELFSRLPDEIPETLISQYLGRLYSDV
VSKRVAPKARELCLAAVDAVLAPYSAATAIR

Specific function: Component of the tagatose-1,6-bisphosphate aldolase kbaYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of kbaY. When expressed alone, kbaZ does not show any aldol

COG id: COG4573

COG function: function code G; Predicted tagatose 6-phosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gatZ/kbaZ family. KbaZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789520, Length=407, Percent_Identity=49.1400491400491, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1788411, Length=406, Percent_Identity=46.0591133004926, Blast_Score=349, Evalue=2e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012062 [H]

Pfam domain/function: PF08013 Tagatose_6_P_K [H]

EC number: 2.7.1.144

Molecular weight: Translated: 46618; Mature: 46486

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSIEENRQTALRKLFGARNLPFPHGVTSVCSAHPLVIEAAVRRAGMEHRAVLIEATCNQ
CCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCHHEEEEEHHHHH
VNQEGGYTAMTPVDFRRFIEDIAAATDFPAERIILGGDHLGPNPWRKLAAEEAMLRAAAM
HHHCCCEEECCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHH
VTAYVEAGFEKIHLDTSMGCAGEPTAIDDELTAARAARLAKAAEEAALRSGRRPPVYIIG
HHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
TEVPPPGGATHALEEIEITRADAAMKTLAVHRASFAEAGLASAMERVIGIVVQPGVEFGN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TDVALYKPERAKSLIRSLDDMPGLVFEAHSTDYQPAEALSALVDGGFAILKVGPGLTFAL
CCEEEECCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHH
REALYGLDVIADVLAGRTPRAGLVTTMEKIMVEQPASWTGHYGGSPDEERLQRHFSYSDR
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCC
IRYYWPDPRASAAVGELFSRLPDEIPETLISQYLGRLYSDVVSKRVAPKARELCLAAVDA
EEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VLAPYSAATAIR
HHCCCHHHHCCC
>Mature Secondary Structure 
TSIEENRQTALRKLFGARNLPFPHGVTSVCSAHPLVIEAAVRRAGMEHRAVLIEATCNQ
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCHHEEEEEHHHHH
VNQEGGYTAMTPVDFRRFIEDIAAATDFPAERIILGGDHLGPNPWRKLAAEEAMLRAAAM
HHHCCCEEECCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHH
VTAYVEAGFEKIHLDTSMGCAGEPTAIDDELTAARAARLAKAAEEAALRSGRRPPVYIIG
HHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
TEVPPPGGATHALEEIEITRADAAMKTLAVHRASFAEAGLASAMERVIGIVVQPGVEFGN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TDVALYKPERAKSLIRSLDDMPGLVFEAHSTDYQPAEALSALVDGGFAILKVGPGLTFAL
CCEEEECCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHH
REALYGLDVIADVLAGRTPRAGLVTTMEKIMVEQPASWTGHYGGSPDEERLQRHFSYSDR
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCC
IRYYWPDPRASAAVGELFSRLPDEIPETLISQYLGRLYSDVVSKRVAPKARELCLAAVDA
EEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VLAPYSAATAIR
HHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-tagatose 6-phosphate

Specific reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate

General reaction: Phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA