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The map label for this gene is tftE [H]

Identifier: 116248885

GI number: 116248885

Start: 222958

End: 224016

Strand: Reverse

Name: tftE [H]

Synonym: pRL120215

Alternate gene names: 116248885

Gene position: 224016-222958 (Counterclockwise)

Preceding gene: 116248886

Following gene: 116248884

Centisome position: 25.75

GC content: 62.51

Gene sequence:

>1059_bases
ATGGTCGCACCTTTCAGATACACGGTCAGCGCGGCCCAGGTGATCTTCGGGAGCGGCTCGTTGAGCCGTCTCGCCGATGC
GATGACAGAGCAGGGCGGCAAACGCGCCCTGATCCTTTCGACCCCGCACCAGAAAGCAGAGGCTGAACGGATCGCAGCTT
CCCTCGGCCCGCTTGCGGCGGGACTATTCCACGATGCGACGATGCATACGCCGGTCGATGTGACCGAGCGCGCGATGGCG
GCCTATAACGCAGCCGGTGCCGATTGCGTCATTGCGATTGGCGGCGGATCGACGATCGGTCTCGGCAAGGCAATTGCCTA
TCGCAACGACGCGCTGCAAATCGTGGTGGCGACGACCTATGCAGGGTCGGAGGTTACACCGATCCTCGGCCAGACAGAGA
ACGGGCAGAAAACGACGGTCCGTGGGGCCGGCATCCTGCCCGAAGTGGTGATCTACGATCCTGAATTGACATTAGGATTG
CCGGTCGCCATCAGCGTCAGCAGCGGGCTCAATGCGATGGCGCATGCGGTCGAAGGTCTCTACGCGCAGGATCGCAACCC
CATTTCGTCAATGATGGCGGTCGAGGGCTTGCGCGCGCTGAAGCAGGCTTTGCCTCAAATCGTCAATGCACCTGGGGATA
TCGAGCCGCGAAGCGAAGCGCTTTACGGTTCCTGGCTGTGCGGCACGGTGCTCGGAGCGGTTGGAATGGCCCTGCATCAC
AAGCTTTGCCATACGCTGGGCGGTAGCTTCGACCTGCCGCATGCGGAAACTCATGCGGTCATTCTTCCCCATTCTGCCGC
CTACAACGCTGAAGCCGCAGCGGACGCGCTAAAGCCCGCTGCCGATCTTTTTGGCGGCTCGCTGGGCAGCGGTCTTTATG
ATTTTGCCGCTTCGATCGGCGCCCCCCTGGCGCTGCGCGATCTGGGTATGAAGGAAGCCGATCTGGATCATGCAGCGGAA
CTCGCCGCCCAGAACCCCTACTGGAACCCGCGCCCGATCGAACGGGAAGCGATCCGGGCTTTGTTGCAGAGCGCCTGGGA
GGGCGCGCGGCCGCGTTAA

Upstream 100 bases:

>100_bases
CATGCTGCAAACTGGTTCGACAGCGCCACCATCTCCGAAGCCGACCGTCTGAAGATCGGTCGCACCAACGCAGTTTCACT
CTTCAAACTCGATCGATAGC

Downstream 100 bases:

>100_bases
TACCTTAGGAGGATGGCCACGTGCCTGAATATTTCAGCGAAGAGAGATCCGTGGAAGCCGTCAACTCGCGGATGGGGCAG
GACATTAATCCGCGCCTGGC

Product: putative maleylacetate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MVAPFRYTVSAAQVIFGSGSLSRLADAMTEQGGKRALILSTPHQKAEAERIAASLGPLAAGLFHDATMHTPVDVTERAMA
AYNAAGADCVIAIGGGSTIGLGKAIAYRNDALQIVVATTYAGSEVTPILGQTENGQKTTVRGAGILPEVVIYDPELTLGL
PVAISVSSGLNAMAHAVEGLYAQDRNPISSMMAVEGLRALKQALPQIVNAPGDIEPRSEALYGSWLCGTVLGAVGMALHH
KLCHTLGGSFDLPHAETHAVILPHSAAYNAEAAADALKPAADLFGGSLGSGLYDFAASIGAPLALRDLGMKEADLDHAAE
LAAQNPYWNPRPIEREAIRALLQSAWEGARPR

Sequences:

>Translated_352_residues
MVAPFRYTVSAAQVIFGSGSLSRLADAMTEQGGKRALILSTPHQKAEAERIAASLGPLAAGLFHDATMHTPVDVTERAMA
AYNAAGADCVIAIGGGSTIGLGKAIAYRNDALQIVVATTYAGSEVTPILGQTENGQKTTVRGAGILPEVVIYDPELTLGL
PVAISVSSGLNAMAHAVEGLYAQDRNPISSMMAVEGLRALKQALPQIVNAPGDIEPRSEALYGSWLCGTVLGAVGMALHH
KLCHTLGGSFDLPHAETHAVILPHSAAYNAEAAADALKPAADLFGGSLGSGLYDFAASIGAPLALRDLGMKEADLDHAAE
LAAQNPYWNPRPIEREAIRALLQSAWEGARPR
>Mature_352_residues
MVAPFRYTVSAAQVIFGSGSLSRLADAMTEQGGKRALILSTPHQKAEAERIAASLGPLAAGLFHDATMHTPVDVTERAMA
AYNAAGADCVIAIGGGSTIGLGKAIAYRNDALQIVVATTYAGSEVTPILGQTENGQKTTVRGAGILPEVVIYDPELTLGL
PVAISVSSGLNAMAHAVEGLYAQDRNPISSMMAVEGLRALKQALPQIVNAPGDIEPRSEALYGSWLCGTVLGAVGMALHH
KLCHTLGGSFDLPHAETHAVILPHSAAYNAEAAADALKPAADLFGGSLGSGLYDFAASIGAPLALRDLGMKEADLDHAAE
LAAQNPYWNPRPIEREAIRALLQSAWEGARPR

Specific function: Fucose metabolism; fourth step. [C]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789163, Length=374, Percent_Identity=25.4010695187166, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI48994951, Length=380, Percent_Identity=25, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87082107, Length=213, Percent_Identity=28.169014084507, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1787493, Length=407, Percent_Identity=24.5700245700246, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17537053, Length=424, Percent_Identity=22.1698113207547, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321181, Length=376, Percent_Identity=27.3936170212766, Blast_Score=120, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.3.1.32 [H]

Molecular weight: Translated: 36557; Mature: 36557

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAPFRYTVSAAQVIFGSGSLSRLADAMTEQGGKRALILSTPHQKAEAERIAASLGPLAA
CCCCCEEHHHHHHHEECCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
GLFHDATMHTPVDVTERAMAAYNAAGADCVIAIGGGSTIGLGKAIAYRNDALQIVVATTY
HHHHCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHEECCCCEEEEEEEEC
AGSEVTPILGQTENGQKTTVRGAGILPEVVIYDPELTLGLPVAISVSSGLNAMAHAVEGL
CCCCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCEEECCCEEEEECCCHHHHHHHHHHH
YAQDRNPISSMMAVEGLRALKQALPQIVNAPGDIEPRSEALYGSWLCGTVLGAVGMALHH
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KLCHTLGGSFDLPHAETHAVILPHSAAYNAEAAADALKPAADLFGGSLGSGLYDFAASIG
HHHHHCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
APLALRDLGMKEADLDHAAELAAQNPYWNPRPIEREAIRALLQSAWEGARPR
CCHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVAPFRYTVSAAQVIFGSGSLSRLADAMTEQGGKRALILSTPHQKAEAERIAASLGPLAA
CCCCCEEHHHHHHHEECCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
GLFHDATMHTPVDVTERAMAAYNAAGADCVIAIGGGSTIGLGKAIAYRNDALQIVVATTY
HHHHCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHEECCCCEEEEEEEEC
AGSEVTPILGQTENGQKTTVRGAGILPEVVIYDPELTLGLPVAISVSSGLNAMAHAVEGL
CCCCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCEEECCCEEEEECCCHHHHHHHHHHH
YAQDRNPISSMMAVEGLRALKQALPQIVNAPGDIEPRSEALYGSWLCGTVLGAVGMALHH
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KLCHTLGGSFDLPHAETHAVILPHSAAYNAEAAADALKPAADLFGGSLGSGLYDFAASIG
HHHHHCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
APLALRDLGMKEADLDHAAELAAQNPYWNPRPIEREAIRALLQSAWEGARPR
CCHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7538273 [H]