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The map label for this gene is srlR [H]

Identifier: 116248832

GI number: 116248832

Start: 159181

End: 159945

Strand: Reverse

Name: srlR [H]

Synonym: pRL120160

Alternate gene names: 116248832

Gene position: 159945-159181 (Counterclockwise)

Preceding gene: 116248833

Following gene: 116248831

Centisome position: 18.38

GC content: 59.74

Gene sequence:

>765_bases
ATGACCGACCATCCCCAGGCACGTCTGCAACACATTCTCGAAGAACTGGCCAAGCATGGCCGGGTCACGGTCAAGGAACT
GGCAGCGGAGTTTTCCGTCAGCCCGGAAACCGTGCGCCGCGACCTGAAGCAGCTGGAGATGGAAGGGCACCTGCGCTGCA
TCTATGGCGGCGGCGTGACGCCGCGTCGGGATGCCGACCAGCCGATCTCGCAACGTATGCGCGTCAATGCCCGTGAAAAG
GCAAAAATCGCAACCCTCGCCGCCAGGGAGCTGCGCGACCATTCCAAGATCTTCCTCGACAGCGGCACGACGATGCTGGC
GCTGTCGCGCTATCTTGTCGATCGGCCGCTGATCAATATCTACACCAACTCGCTGGATATCATCCAGACCTTGTCGGGGG
TGGAATCCAATAACGTGGTCGCGGTCGGCGGCGTTCTACGGCCGAGCTACCGGGCGTTTCTCGGCACCGATACGCTCAAC
GTGATCCGCGAACATCTCTTCGATATCGCCTTCGTCAGCGCGGTGACGGTCGATATCAACCTCGGTTTCATGGACCTCGG
CGAGGACGAGGCGCTGGTGCGCCGGGCGTTGCGCCGCCATGCCAAGCAGGTCGTGATGCTCGCCGACAGCAGCAAGTTCG
GCCGCCAGGGTAATTTCTGCACCTATAATTTTCGTGACGTTGATCTGCTCATCACTGATGCGCCTCCGCGGGCAGATTTT
CTTGAAAAGCTTGAGGAGGCGCAAGTGAAGGTGATTTATGCTTGA

Upstream 100 bases:

>100_bases
TCGAAACCCGGGGGGATCAGAGGATGAAAGAAACAGCAACTGCGGCGGGACACGCCTGCTCGACAGACTTGCCCATGGGC
TTGTGACCGGGAAAGCCCTC

Downstream 100 bases:

>100_bases
AACCCGCAGTGAACCTGCATCCCTGCCTGAGGTCGATGCCGAAGCCCTGCACCGGATGATGGAGGAAGTCTCCGTCTTTG
GCGGCGGGCCGGGTGGTGCG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTDHPQARLQHILEELAKHGRVTVKELAAEFSVSPETVRRDLKQLEMEGHLRCIYGGGVTPRRDADQPISQRMRVNAREK
AKIATLAARELRDHSKIFLDSGTTMLALSRYLVDRPLINIYTNSLDIIQTLSGVESNNVVAVGGVLRPSYRAFLGTDTLN
VIREHLFDIAFVSAVTVDINLGFMDLGEDEALVRRALRRHAKQVVMLADSSKFGRQGNFCTYNFRDVDLLITDAPPRADF
LEKLEEAQVKVIYA

Sequences:

>Translated_254_residues
MTDHPQARLQHILEELAKHGRVTVKELAAEFSVSPETVRRDLKQLEMEGHLRCIYGGGVTPRRDADQPISQRMRVNAREK
AKIATLAARELRDHSKIFLDSGTTMLALSRYLVDRPLINIYTNSLDIIQTLSGVESNNVVAVGGVLRPSYRAFLGTDTLN
VIREHLFDIAFVSAVTVDINLGFMDLGEDEALVRRALRRHAKQVVMLADSSKFGRQGNFCTYNFRDVDLLITDAPPRADF
LEKLEEAQVKVIYA
>Mature_253_residues
TDHPQARLQHILEELAKHGRVTVKELAAEFSVSPETVRRDLKQLEMEGHLRCIYGGGVTPRRDADQPISQRMRVNAREKA
KIATLAARELRDHSKIFLDSGTTMLALSRYLVDRPLINIYTNSLDIIQTLSGVESNNVVAVGGVLRPSYRAFLGTDTLNV
IREHLFDIAFVSAVTVDINLGFMDLGEDEALVRRALRRHAKQVVMLADSSKFGRQGNFCTYNFRDVDLLITDAPPRADFL
EKLEEAQVKVIYA

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=249, Percent_Identity=34.5381526104418, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1789829, Length=240, Percent_Identity=29.1666666666667, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788069, Length=248, Percent_Identity=32.258064516129, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI226510968, Length=230, Percent_Identity=31.7391304347826, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1789519, Length=250, Percent_Identity=28.8, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87082344, Length=252, Percent_Identity=27.3809523809524, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789170, Length=230, Percent_Identity=28.2608695652174, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790635, Length=248, Percent_Identity=25.8064516129032, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787540, Length=246, Percent_Identity=28.0487804878049, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787063, Length=250, Percent_Identity=24.4, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790753, Length=219, Percent_Identity=24.6575342465753, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28575; Mature: 28444

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDHPQARLQHILEELAKHGRVTVKELAAEFSVSPETVRRDLKQLEMEGHLRCIYGGGVT
CCCCHHHHHHHHHHHHHHCCCEEHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCC
PRRDADQPISQRMRVNAREKAKIATLAARELRDHSKIFLDSGTTMLALSRYLVDRPLINI
CCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCHHEE
YTNSLDIIQTLSGVESNNVVAVGGVLRPSYRAFLGTDTLNVIREHLFDIAFVSAVTVDIN
CCCHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHEEEEEEE
LGFMDLGEDEALVRRALRRHAKQVVMLADSSKFGRQGNFCTYNFRDVDLLITDAPPRADF
ECEEECCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCEEEEECCEEEEEEECCCCHHHH
LEKLEEAQVKVIYA
HHHHHHCCEEEEEC
>Mature Secondary Structure 
TDHPQARLQHILEELAKHGRVTVKELAAEFSVSPETVRRDLKQLEMEGHLRCIYGGGVT
CCCHHHHHHHHHHHHHHCCCEEHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCC
PRRDADQPISQRMRVNAREKAKIATLAARELRDHSKIFLDSGTTMLALSRYLVDRPLINI
CCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCHHEE
YTNSLDIIQTLSGVESNNVVAVGGVLRPSYRAFLGTDTLNVIREHLFDIAFVSAVTVDIN
CCCHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHEEEEEEE
LGFMDLGEDEALVRRALRRHAKQVVMLADSSKFGRQGNFCTYNFRDVDLLITDAPPRADF
ECEEECCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCEEEEECCEEEEEEECCCCHHHH
LEKLEEAQVKVIYA
HHHHHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062173; 9278503; 9205837 [H]