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The map label for this gene is ywqM [H]

Identifier: 116248828

GI number: 116248828

Start: 154712

End: 155620

Strand: Direct

Name: ywqM [H]

Synonym: pRL120155

Alternate gene names: 116248828

Gene position: 154712-155620 (Clockwise)

Preceding gene: 116248823

Following gene: 116248839

Centisome position: 17.78

GC content: 59.85

Gene sequence:

>909_bases
ATGAGCCTCAGTTTCCGGCAGCTCCGCTATTTCGTCGCAACCGCCGAGCAAGGACAGATCTCCTATGCAGCGGCACAGCT
CTCGATCTCGCAGTCGGCAGTGACGACCGCCATCAAGGAACTGGAAAAATCGATCGGCGTTGCTCTTTTCACGCGCATGC
CGCAGGGCATGGAACTGACCGCCGCCGGCCGGCAGTTTCTTTCCTACGCCTACGAGATCCTCGCCAAGGTCGATGAGGCA
ACGCATCTGAACTATGTCAGCAGCGACATCGAGGGCGATCTGACTGTTGCGGCGACCTACACCGTCATCGGCTACTTCCT
GCCGCTCCACATAGAGCGCATGCGGCGACTCTATCCTAAGCTGCGCATCCAGCTTTACGAGGTAAACCGCGAGTCGATCG
AGGAAGGCCTGCTGGTCAACCGGTACGACATTTCGGTACTTCTCACCTCGAATATCCTGAATACCGCGCTCACCACCGAG
ACGCTTTTGCGTTCCATCCGCAGGCTCTGGGTGGCGGCGCAGCATCCGCTACTGAAGCATGTGGGCGTCGGCCTGCAGGA
AATCGCCGAGGAGCCCTACATCATGCTGACGGTGGACGAGGCGGCGTATTCGTCGCTGAAGTACTGGAGCACGACACCCT
ATCAACCCCGCGTGATGCTGCGCACCTCGTCGATCGAGGCAGTACGCTCCATGGTCGCTAACAACCTCGGCGTCGCGATC
CTGTCGGATATGGTACACCGCCCCTGGTCGCTGGAAGGCCGGCGGATCGAGACAATCAACATCAAGGATCCGGTGCCACC
GATGGATGTCGGCCTCGCTTGGCGCGCCAACACCGACTTCACTCCAGCCATGCATGCCTTTCGCCGATATTTTCAGCAGG
CGTTCGGCCTGCCGGGCACCAATGCATGA

Upstream 100 bases:

>100_bases
TCGATTCCGCCTCAAATTCGTAGAGCACTCGCATAAGTTAAAAGCAGTCGATCGGATTTATTCAAGCCGAATTCAGATAA
TTCGATGGGAAAAACAGATC

Downstream 100 bases:

>100_bases
ATTCGTCTTCGAGCCTCGGCAGGTCAGGAATGGCTGCCGGTACGCGATGGTCCTCCGGACCACCAAAGCGTCCGAGATTT
GTGGCAACGACGACTTGCAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MSLSFRQLRYFVATAEQGQISYAAAQLSISQSAVTTAIKELEKSIGVALFTRMPQGMELTAAGRQFLSYAYEILAKVDEA
THLNYVSSDIEGDLTVAATYTVIGYFLPLHIERMRRLYPKLRIQLYEVNRESIEEGLLVNRYDISVLLTSNILNTALTTE
TLLRSIRRLWVAAQHPLLKHVGVGLQEIAEEPYIMLTVDEAAYSSLKYWSTTPYQPRVMLRTSSIEAVRSMVANNLGVAI
LSDMVHRPWSLEGRRIETINIKDPVPPMDVGLAWRANTDFTPAMHAFRRYFQQAFGLPGTNA

Sequences:

>Translated_302_residues
MSLSFRQLRYFVATAEQGQISYAAAQLSISQSAVTTAIKELEKSIGVALFTRMPQGMELTAAGRQFLSYAYEILAKVDEA
THLNYVSSDIEGDLTVAATYTVIGYFLPLHIERMRRLYPKLRIQLYEVNRESIEEGLLVNRYDISVLLTSNILNTALTTE
TLLRSIRRLWVAAQHPLLKHVGVGLQEIAEEPYIMLTVDEAAYSSLKYWSTTPYQPRVMLRTSSIEAVRSMVANNLGVAI
LSDMVHRPWSLEGRRIETINIKDPVPPMDVGLAWRANTDFTPAMHAFRRYFQQAFGLPGTNA
>Mature_301_residues
SLSFRQLRYFVATAEQGQISYAAAQLSISQSAVTTAIKELEKSIGVALFTRMPQGMELTAAGRQFLSYAYEILAKVDEAT
HLNYVSSDIEGDLTVAATYTVIGYFLPLHIERMRRLYPKLRIQLYEVNRESIEEGLLVNRYDISVLLTSNILNTALTTET
LLRSIRRLWVAAQHPLLKHVGVGLQEIAEEPYIMLTVDEAAYSSLKYWSTTPYQPRVMLRTSSIEAVRSMVANNLGVAIL
SDMVHRPWSLEGRRIETINIKDPVPPMDVGLAWRANTDFTPAMHAFRRYFQQAFGLPGTNA

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=301, Percent_Identity=29.5681063122924, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI145693105, Length=297, Percent_Identity=27.9461279461279, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787879, Length=308, Percent_Identity=29.5454545454545, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082132, Length=309, Percent_Identity=24.9190938511327, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788481, Length=247, Percent_Identity=27.1255060728745, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI87081904, Length=195, Percent_Identity=31.2820512820513, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787530, Length=251, Percent_Identity=23.5059760956175, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1787806, Length=155, Percent_Identity=30.3225806451613, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790399, Length=282, Percent_Identity=24.113475177305, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788296, Length=244, Percent_Identity=25.8196721311475, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788748, Length=164, Percent_Identity=26.8292682926829, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787601, Length=294, Percent_Identity=23.1292517006803, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788626, Length=272, Percent_Identity=27.2058823529412, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786401, Length=256, Percent_Identity=25.390625, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790208, Length=293, Percent_Identity=22.5255972696246, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788887, Length=296, Percent_Identity=22.972972972973, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34068; Mature: 33937

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSFRQLRYFVATAEQGQISYAAAQLSISQSAVTTAIKELEKSIGVALFTRMPQGMELT
CCCCHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCEEH
AAGRQFLSYAYEILAKVDEATHLNYVSSDIEGDLTVAATYTVIGYFLPLHIERMRRLYPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
LRIQLYEVNRESIEEGLLVNRYDISVLLTSNILNTALTTETLLRSIRRLWVAAQHPLLKH
HEEEEEECCHHHHHCCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VGVGLQEIAEEPYIMLTVDEAAYSSLKYWSTTPYQPRVMLRTSSIEAVRSMVANNLGVAI
HCCCHHHHCCCCEEEEEECHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCHHH
LSDMVHRPWSLEGRRIETINIKDPVPPMDVGLAWRANTDFTPAMHAFRRYFQQAFGLPGT
HHHHHCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCC
NA
CC
>Mature Secondary Structure 
SLSFRQLRYFVATAEQGQISYAAAQLSISQSAVTTAIKELEKSIGVALFTRMPQGMELT
CCCHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCEEH
AAGRQFLSYAYEILAKVDEATHLNYVSSDIEGDLTVAATYTVIGYFLPLHIERMRRLYPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
LRIQLYEVNRESIEEGLLVNRYDISVLLTSNILNTALTTETLLRSIRRLWVAAQHPLLKH
HEEEEEECCHHHHHCCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VGVGLQEIAEEPYIMLTVDEAAYSSLKYWSTTPYQPRVMLRTSSIEAVRSMVANNLGVAI
HCCCHHHHCCCCEEEEEECHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCHHH
LSDMVHRPWSLEGRRIETINIKDPVPPMDVGLAWRANTDFTPAMHAFRRYFQQAFGLPGT
HHHHHCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCC
NA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]