| Definition | Rhizobium leguminosarum bv. viciae 3841 plasmid pRL12, complete sequence. |
|---|---|
| Accession | NC_008378 |
| Length | 870,021 |
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The map label for this gene is yxbG [H]
Identifier: 116248799
GI number: 116248799
Start: 124043
End: 124804
Strand: Reverse
Name: yxbG [H]
Synonym: pRL120125
Alternate gene names: 116248799
Gene position: 124804-124043 (Counterclockwise)
Preceding gene: 116248800
Following gene: 116248798
Centisome position: 14.34
GC content: 62.99
Gene sequence:
>762_bases ATGACGACGCCGATGTCACGTCTTGAAGGCAAGGTGATTTTCCTGACCGGTGCAGCAAGCGGCATCGGCGCGGCGATCGC GCGCCGATGCATCGACGAGAAAGCCTTCGTGATCTGCGCAGACCAATCGCTCGATGGTGCCGACGCGCTTGCAAAATCGC TTGGCCCGCAGGCGTTGGGCATTCGGTGCGAGGTTACCGAGAGCGGCTCGGTCAAGCGCGCGGTGGAGACTAGCCTGGAA CATTTCGGGCGGCTCGATGGTCTTGTGCATAACGCGGCTGCACCTTCGATGGATGGTACGGTTATCGACCTTGCCGCGCC GCAATGGCAGTTGGAAATCGATGTCATACTGACCGGTGCCTTCCTCGCCAGCAAACATACGCTTCCGGCCATGATCGAAG GTGGCGGCGGTTCCGTCGTCTTCATCGCATCGCAATTCGCTCATGTGGCAACCGGCAAGGCTGTCGCCTACTGCGCTGCA AAGGCCGGTCTCGTGCATCTCGCCAAGGCTATGGCGGTTGACCATGCGGCGGATGGCATCCGCGTCAACAGCCTTTCGCC CGGCGCTGTCGCCACGCCGCGGCTGCTGCAACGGTGGCCGGATCTCGACGCGGCCAATGCCGGGCTGGGGCCTGCGCATT TGCTCGGACGCATCGGACAACCGGAGGAAATAGCCGCCGCCACGGCCTTTTTGTTGTCGTCGGATGCATCCTTCGTCACC GGAACCGATCTCCTGGCCGACGGCGGCTACGCGACGCGCTGA
Upstream 100 bases:
>100_bases GGAAGGACGGAAAAATCCTGGCGGAACCGGGCCGCGGCCAATTCATCGCCAGAGAGCGGCCTTTTCCGCCGCAGCAGGGA CTTTCTAAGGTCCTCGCATC
Downstream 100 bases:
>100_bases TATCTGTATTGAAAATCTTTGGATGGATTTGAAATGACCCTTCTCGTCACCGGTGGAACCGGCTTCGTCATGAGCGTCCT TGCACGGGAATGGCTCGAAC
Product: putative short-chain dehydrogenase
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 253; Mature: 252
Protein sequence:
>253_residues MTTPMSRLEGKVIFLTGAASGIGAAIARRCIDEKAFVICADQSLDGADALAKSLGPQALGIRCEVTESGSVKRAVETSLE HFGRLDGLVHNAAAPSMDGTVIDLAAPQWQLEIDVILTGAFLASKHTLPAMIEGGGGSVVFIASQFAHVATGKAVAYCAA KAGLVHLAKAMAVDHAADGIRVNSLSPGAVATPRLLQRWPDLDAANAGLGPAHLLGRIGQPEEIAAATAFLLSSDASFVT GTDLLADGGYATR
Sequences:
>Translated_253_residues MTTPMSRLEGKVIFLTGAASGIGAAIARRCIDEKAFVICADQSLDGADALAKSLGPQALGIRCEVTESGSVKRAVETSLE HFGRLDGLVHNAAAPSMDGTVIDLAAPQWQLEIDVILTGAFLASKHTLPAMIEGGGGSVVFIASQFAHVATGKAVAYCAA KAGLVHLAKAMAVDHAADGIRVNSLSPGAVATPRLLQRWPDLDAANAGLGPAHLLGRIGQPEEIAAATAFLLSSDASFVT GTDLLADGGYATR >Mature_252_residues TTPMSRLEGKVIFLTGAASGIGAAIARRCIDEKAFVICADQSLDGADALAKSLGPQALGIRCEVTESGSVKRAVETSLEH FGRLDGLVHNAAAPSMDGTVIDLAAPQWQLEIDVILTGAFLASKHTLPAMIEGGGGSVVFIASQFAHVATGKAVAYCAAK AGLVHLAKAMAVDHAADGIRVNSLSPGAVATPRLLQRWPDLDAANAGLGPAHLLGRIGQPEEIAAATAFLLSSDASFVTG TDLLADGGYATR
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=32.5301204819277, Blast_Score=125, Evalue=3e-29, Organism=Homo sapiens, GI59889578, Length=225, Percent_Identity=34.6666666666667, Blast_Score=114, Evalue=7e-26, Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=29.4573643410853, Blast_Score=110, Evalue=2e-24, Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=31.3253012048193, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=32.6359832635983, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=29.7619047619048, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=29.9610894941634, Blast_Score=95, Evalue=8e-20, Organism=Homo sapiens, GI66933014, Length=251, Percent_Identity=31.4741035856574, Blast_Score=94, Evalue=9e-20, Organism=Homo sapiens, GI10190704, Length=246, Percent_Identity=31.7073170731707, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=32.0441988950276, Blast_Score=85, Evalue=5e-17, Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=29.5, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=30.8510638297872, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=27.4590163934426, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4503301, Length=256, Percent_Identity=26.5625, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=29.2490118577075, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI40254986, Length=193, Percent_Identity=29.0155440414508, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI4504505, Length=201, Percent_Identity=26.865671641791, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI224922801, Length=171, Percent_Identity=28.6549707602339, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=34.7107438016529, Blast_Score=123, Evalue=1e-29, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=33.8582677165354, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=31.9838056680162, Blast_Score=97, Evalue=9e-22, Organism=Escherichia coli, GI1786812, Length=249, Percent_Identity=32.5301204819277, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=32.520325203252, Blast_Score=94, Evalue=8e-21, Organism=Escherichia coli, GI87082160, Length=257, Percent_Identity=28.7937743190661, Blast_Score=91, Evalue=9e-20, Organism=Escherichia coli, GI1790717, Length=245, Percent_Identity=30.2040816326531, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=25.4980079681275, Blast_Score=78, Evalue=7e-16, Organism=Escherichia coli, GI2367365, Length=248, Percent_Identity=30.6451612903226, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=27.9527559055118, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1789378, Length=239, Percent_Identity=24.6861924686192, Blast_Score=62, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=31.2741312741313, Blast_Score=125, Evalue=3e-29, Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=29.9610894941634, Blast_Score=104, Evalue=5e-23, Organism=Caenorhabditis elegans, GI17555706, Length=244, Percent_Identity=30.7377049180328, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=31.2, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17563726, Length=271, Percent_Identity=31.3653136531365, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=28.4090909090909, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17536651, Length=257, Percent_Identity=28.4046692607004, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI72000259, Length=267, Percent_Identity=29.5880149812734, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=25.830258302583, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=29.277566539924, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=28.8389513108614, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=29.7397769516729, Blast_Score=80, Evalue=8e-16, Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=27.8810408921933, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI71994600, Length=240, Percent_Identity=29.1666666666667, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=29.5546558704453, Blast_Score=78, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=29.6296296296296, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17536025, Length=263, Percent_Identity=28.8973384030418, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=27.6515151515151, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=29.5880149812734, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=30.1587301587302, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI193204405, Length=272, Percent_Identity=26.8382352941176, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17562910, Length=277, Percent_Identity=25.9927797833935, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17565030, Length=268, Percent_Identity=27.9850746268657, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17560220, Length=269, Percent_Identity=27.1375464684015, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=27.037037037037, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17538486, Length=275, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17561272, Length=253, Percent_Identity=27.6679841897233, Blast_Score=64, Evalue=1e-10, Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=29.8039215686275, Blast_Score=85, Evalue=1e-17, Organism=Saccharomyces cerevisiae, GI6322861, Length=233, Percent_Identity=27.8969957081545, Blast_Score=69, Evalue=5e-13, Organism=Saccharomyces cerevisiae, GI6322227, Length=226, Percent_Identity=25.6637168141593, Blast_Score=64, Evalue=2e-11, Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=34.5238095238095, Blast_Score=138, Evalue=3e-33, Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=31.640625, Blast_Score=110, Evalue=7e-25, Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=35.6275303643725, Blast_Score=110, Evalue=7e-25, Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=31.1023622047244, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=32.520325203252, Blast_Score=94, Evalue=9e-20, Organism=Drosophila melanogaster, GI24644339, Length=247, Percent_Identity=29.1497975708502, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=28.3464566929134, Blast_Score=88, Evalue=7e-18, Organism=Drosophila melanogaster, GI24644337, Length=118, Percent_Identity=38.9830508474576, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI18859837, Length=259, Percent_Identity=27.027027027027, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI21357673, Length=193, Percent_Identity=27.979274611399, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI17737361, Length=199, Percent_Identity=29.6482412060301, Blast_Score=68, Evalue=6e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 25838; Mature: 25707
Theoretical pI: Translated: 5.87; Mature: 5.87
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTTPMSRLEGKVIFLTGAASGIGAAIARRCIDEKAFVICADQSLDGADALAKSLGPQALG CCCCHHHHCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCCEE IRCEVTESGSVKRAVETSLEHFGRLDGLVHNAAAPSMDGTVIDLAAPQWQLEIDVILTGA EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEEEEEEH FLASKHTLPAMIEGGGGSVVFIASQFAHVATGKAVAYCAAKAGLVHLAKAMAVDHAADGI HHHCCCCCCEEEECCCCCEEEEECHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCE RVNSLSPGAVATPRLLQRWPDLDAANAGLGPAHLLGRIGQPEEIAAATAFLLSSDASFVT EEECCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCEEE GTDLLADGGYATR CCHHEECCCCCCC >Mature Secondary Structure TTPMSRLEGKVIFLTGAASGIGAAIARRCIDEKAFVICADQSLDGADALAKSLGPQALG CCCHHHHCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCCEE IRCEVTESGSVKRAVETSLEHFGRLDGLVHNAAAPSMDGTVIDLAAPQWQLEIDVILTGA EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEEEEEEH FLASKHTLPAMIEGGGGSVVFIASQFAHVATGKAVAYCAAKAGLVHLAKAMAVDHAADGI HHHCCCCCCEEEECCCCCEEEEECHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCE RVNSLSPGAVATPRLLQRWPDLDAANAGLGPAHLLGRIGQPEEIAAATAFLLSSDASFVT EEECCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCEEE GTDLLADGGYATR CCHHEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7584049; 9384377 [H]