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The map label for this gene is mcpA [H]

Identifier: 116248744

GI number: 116248744

Start: 69629

End: 71422

Strand: Direct

Name: mcpA [H]

Synonym: pRL120068

Alternate gene names: 116248744

Gene position: 69629-71422 (Clockwise)

Preceding gene: 116248743

Following gene: 116248746

Centisome position: 8.0

GC content: 58.47

Gene sequence:

>1794_bases
TTGCGCGTGAGTATTCTTAATCGTGGTGCAAATGCTGTCGCGGCTCTTGCCGCTCTATCGAATTCGCAAGCCATGATCGA
GTTTGATCTATCGGGCAGGATCCTCACCGCGAACGAAAACTTCTGCAGGGCGCTCGGCTACGAGTTGAGGGAGATTGTCG
GAAAACATCACAGCATGTTTGTCGAGCCTGCCTATGCGTCGTCGGCAGAATACAAGGCTTTCTGGACGAAGCTCGCAGCC
GGGAAATTCGACCAGCAGCAATATAAGCGTCTCGGAAAAGGCGGGCGCGAGGTCTGGATCGAAGCATCCTACAATCCCGT
GTTCCGACGCGGGAAGCCGGTCAAGGTCATCAAGATTGCAACTGACATCACCGCGCAGAAGCTGAAGTCTGCCGAGGATT
CGGGCAAGATCGATGCATTGTCCCGGGCTCAGGCGATCATCGAATTCACGCCGGCCGGCGAAATCCTGACCGCCAACGAC
AATTTCCTGTCGACGCTTGGTTATTCGCTTGCCGAAATCCAGGGCAAACATCACTCGATGTTCTGTGAAGCCGACTACTC
GAGATCGGAGGCTTACAAGGAATTCTGGCGGAGACTAGCGAGCGGCCAGCTGGTTGCCGACGAATTCATGCGTGTGGGCA
AGGGCGGCCGGAAGGTCTACATTCAGGCTTCCTACAATCCGATTTTCGACCTGAATGGCAAAGTGTTCAAAGTCGTGAAA
TTCGCAACCGATGTCACGGCGCGCGTCGAAAATGTCGAACAACTTGCCCGTTGCCTGACGAATCTTGCGGACGGCGACCT
GTCGCAGATGATCCAGAAGCCTTTCATTCCTTCGCTGGAAAGGCTGCGTGCCGACTTCAACAGCGCCTCGGAGAAGCTGA
AGGGCGCAATGGCAACGGTTGCCGAAAATGCCAAGGCGATATCAGCCGGTTCCAACGAAATCCGCACAGCGGCCGACGAC
TTGGCAAAGCGTACCGAGCAGCAAGCGGCATCCGTCGAAGAAACGGCCGCCGCCCTTGAGGAAATCACGACGACGGTCAA
GGATTCGAGCCGCCGCGCCGAAGAGGCCGGTCAACTCGTGGGGCGCGCCAGAAATCACGCCGAGCATTCCGGCCAGGTGG
TGCGTGACGCCATCGGAGCGATGGACCAGATTGAAAACTCGTCACGCGAAATTTCCAATATCATCGGAGTCATCGATGAG
ATTGCCTTCCAGACGAACCTTTTGGCGCTCAATGCCGGCGTAGAGGCGGCACGAGCAGGGGAGGCGGGCAAGGGTTTTGC
GGTCGTTGCCCAGGAGGTCCGTGAGCTGGCGCAGCGGTCGGCGAAAGCTGCCAAGGAGATAAAGAGCCTGATCACAGCGT
CCGGTTCTCATGTCGCAAACGGCGTCGCCCTCGTGACGAATGCCGGATCCGCGCTCCAGGAAATCGCCAGTCAGGTTCAC
GAAATCAATACCAACGTCACGGCGATCGTGGAGGCGGCGCGCGAGCAATCGACTGCGCTCGGCGGGATCAGCCAGTCCAT
CAACACCGTCGACCAGGGAACGCAGCAGAATGCCGCAATGGTCGAGGAGCAGACGGCTGCGAGCCATGGTCTCGCCCGAG
AGGCTGCCGCGCTCTTCGAGCTTCTTGAACAGTTCCGTTTCAACGATGCGCCGAGATCCAGGTCTTCGTTTGCGCAGGCG
GATCGTCACCCCGCCGCACCGACGGCTTTGAAAGTCGTTCGCAATTCGCCCCTCGCATCCATCCAGCGCGGGTCGGCCTC
CGTCGCGCTGAAGTCCGACTGGGAAGAGTTCTGA

Upstream 100 bases:

>100_bases
AAAATATCCTGCACGTTATATTCATAATTAAATCCTCGTTAATAAGCATAAGCGAATATTCGCGACATGGCTGGACCAAC
AGCAATGAAATCTAGGGGGA

Downstream 100 bases:

>100_bases
TTACGCTGACTGAGCCATTCTCGGCAGTGTTGGCGGCAATCAATCGAGCGACCACGAGCCGGGATAGTTCGGCTTGCGAC
GCTCGATCCACCCGTCGAGC

Product: putative methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 597; Mature: 597

Protein sequence:

>597_residues
MRVSILNRGANAVAALAALSNSQAMIEFDLSGRILTANENFCRALGYELREIVGKHHSMFVEPAYASSAEYKAFWTKLAA
GKFDQQQYKRLGKGGREVWIEASYNPVFRRGKPVKVIKIATDITAQKLKSAEDSGKIDALSRAQAIIEFTPAGEILTAND
NFLSTLGYSLAEIQGKHHSMFCEADYSRSEAYKEFWRRLASGQLVADEFMRVGKGGRKVYIQASYNPIFDLNGKVFKVVK
FATDVTARVENVEQLARCLTNLADGDLSQMIQKPFIPSLERLRADFNSASEKLKGAMATVAENAKAISAGSNEIRTAADD
LAKRTEQQAASVEETAAALEEITTTVKDSSRRAEEAGQLVGRARNHAEHSGQVVRDAIGAMDQIENSSREISNIIGVIDE
IAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSAKAAKEIKSLITASGSHVANGVALVTNAGSALQEIASQVH
EINTNVTAIVEAAREQSTALGGISQSINTVDQGTQQNAAMVEEQTAASHGLAREAAALFELLEQFRFNDAPRSRSSFAQA
DRHPAAPTALKVVRNSPLASIQRGSASVALKSDWEEF

Sequences:

>Translated_597_residues
MRVSILNRGANAVAALAALSNSQAMIEFDLSGRILTANENFCRALGYELREIVGKHHSMFVEPAYASSAEYKAFWTKLAA
GKFDQQQYKRLGKGGREVWIEASYNPVFRRGKPVKVIKIATDITAQKLKSAEDSGKIDALSRAQAIIEFTPAGEILTAND
NFLSTLGYSLAEIQGKHHSMFCEADYSRSEAYKEFWRRLASGQLVADEFMRVGKGGRKVYIQASYNPIFDLNGKVFKVVK
FATDVTARVENVEQLARCLTNLADGDLSQMIQKPFIPSLERLRADFNSASEKLKGAMATVAENAKAISAGSNEIRTAADD
LAKRTEQQAASVEETAAALEEITTTVKDSSRRAEEAGQLVGRARNHAEHSGQVVRDAIGAMDQIENSSREISNIIGVIDE
IAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSAKAAKEIKSLITASGSHVANGVALVTNAGSALQEIASQVH
EINTNVTAIVEAAREQSTALGGISQSINTVDQGTQQNAAMVEEQTAASHGLAREAAALFELLEQFRFNDAPRSRSSFAQA
DRHPAAPTALKVVRNSPLASIQRGSASVALKSDWEEF
>Mature_597_residues
MRVSILNRGANAVAALAALSNSQAMIEFDLSGRILTANENFCRALGYELREIVGKHHSMFVEPAYASSAEYKAFWTKLAA
GKFDQQQYKRLGKGGREVWIEASYNPVFRRGKPVKVIKIATDITAQKLKSAEDSGKIDALSRAQAIIEFTPAGEILTAND
NFLSTLGYSLAEIQGKHHSMFCEADYSRSEAYKEFWRRLASGQLVADEFMRVGKGGRKVYIQASYNPIFDLNGKVFKVVK
FATDVTARVENVEQLARCLTNLADGDLSQMIQKPFIPSLERLRADFNSASEKLKGAMATVAENAKAISAGSNEIRTAADD
LAKRTEQQAASVEETAAALEEITTTVKDSSRRAEEAGQLVGRARNHAEHSGQVVRDAIGAMDQIENSSREISNIIGVIDE
IAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSAKAAKEIKSLITASGSHVANGVALVTNAGSALQEIASQVH
EINTNVTAIVEAAREQSTALGGISQSINTVDQGTQQNAAMVEEQTAASHGLAREAAALFELLEQFRFNDAPRSRSSFAQA
DRHPAAPTALKVVRNSPLASIQRGSASVALKSDWEEF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=288, Percent_Identity=43.4027777777778, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI2367378, Length=324, Percent_Identity=42.9012345679012, Blast_Score=194, Evalue=9e-51,
Organism=Escherichia coli, GI1787690, Length=314, Percent_Identity=39.8089171974522, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1788194, Length=304, Percent_Identity=40.1315789473684, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1789453, Length=239, Percent_Identity=38.4937238493724, Blast_Score=153, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 64440; Mature: 64440

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVSILNRGANAVAALAALSNSQAMIEFDLSGRILTANENFCRALGYELREIVGKHHSMF
CEEEEECCCHHHHHHHHHHCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHCCHHHEE
VEPAYASSAEYKAFWTKLAAGKFDQQQYKRLGKGGREVWIEASYNPVFRRGKPVKVIKIA
ECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEECCCCHHHHCCCCEEEEEEE
TDITAQKLKSAEDSGKIDALSRAQAIIEFTPAGEILTANDNFLSTLGYSLAEIQGKHHSM
HHHHHHHHHCCCCCCCHHHHHHHHHHEEECCCCCEEECCCCHHHHHHHHHHHHCCCCCCE
FCEADYSRSEAYKEFWRRLASGQLVADEFMRVGKGGRKVYIQASYNPIFDLNGKVFKVVK
EEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCEEECCCHHHHHHH
FATDVTARVENVEQLARCLTNLADGDLSQMIQKPFIPSLERLRADFNSASEKLKGAMATV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AENAKAISAGSNEIRTAADDLAKRTEQQAASVEETAAALEEITTTVKDSSRRAEEAGQLV
HHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRARNHAEHSGQVVRDAIGAMDQIENSSREISNIIGVIDEIAFQTNLLALNAGVEAARAG
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCC
EAGKGFAVVAQEVRELAQRSAKAAKEIKSLITASGSHVANGVALVTNAGSALQEIASQVH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEEECCCHHHHHHHHHHH
EINTNVTAIVEAAREQSTALGGISQSINTVDQGTQQNAAMVEEQTAASHGLAREAAALFE
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLEQFRFNDAPRSRSSFAQADRHPAAPTALKVVRNSPLASIQRGSASVALKSDWEEF
HHHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHHHCCCHHHHHCCCCCEEECCCCCCC
>Mature Secondary Structure
MRVSILNRGANAVAALAALSNSQAMIEFDLSGRILTANENFCRALGYELREIVGKHHSMF
CEEEEECCCHHHHHHHHHHCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHCCHHHEE
VEPAYASSAEYKAFWTKLAAGKFDQQQYKRLGKGGREVWIEASYNPVFRRGKPVKVIKIA
ECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEECCCCHHHHCCCCEEEEEEE
TDITAQKLKSAEDSGKIDALSRAQAIIEFTPAGEILTANDNFLSTLGYSLAEIQGKHHSM
HHHHHHHHHCCCCCCCHHHHHHHHHHEEECCCCCEEECCCCHHHHHHHHHHHHCCCCCCE
FCEADYSRSEAYKEFWRRLASGQLVADEFMRVGKGGRKVYIQASYNPIFDLNGKVFKVVK
EEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCEEECCCHHHHHHH
FATDVTARVENVEQLARCLTNLADGDLSQMIQKPFIPSLERLRADFNSASEKLKGAMATV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AENAKAISAGSNEIRTAADDLAKRTEQQAASVEETAAALEEITTTVKDSSRRAEEAGQLV
HHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRARNHAEHSGQVVRDAIGAMDQIENSSREISNIIGVIDEIAFQTNLLALNAGVEAARAG
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCC
EAGKGFAVVAQEVRELAQRSAKAAKEIKSLITASGSHVANGVALVTNAGSALQEIASQVH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEEECCCHHHHHHHHHHH
EINTNVTAIVEAAREQSTALGGISQSINTVDQGTQQNAAMVEEQTAASHGLAREAAALFE
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLEQFRFNDAPRSRSSFAQADRHPAAPTALKVVRNSPLASIQRGSASVALKSDWEEF
HHHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHHHCCCHHHHHCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]