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The map label for this gene is mcpA [H]

Identifier: 116248732

GI number: 116248732

Start: 55461

End: 57380

Strand: Reverse

Name: mcpA [H]

Synonym: pRL120056

Alternate gene names: 116248732

Gene position: 57380-55461 (Counterclockwise)

Preceding gene: 116248734

Following gene: 116248721

Centisome position: 6.6

GC content: 60.1

Gene sequence:

>1920_bases
ATGCCAAAAGAATTAACCATATCTCAGTGTTCTTGCGAAATAATGCCATACGTAGATCAGGCATCTCGAAGCAGAGAGGC
CAAAAGTTATTTGGAGGCAGTCTTGGCACTTACCATTGCTCGTAGTTTGGTGGCGTTTGGTGTCGCCGTTTCAGCCGGCC
TTTTCATGTCGATCGGTTTGCAGCAATCGGCGCTCGAACGGCTGAAAGTCAACGGGCCGGTTTACGAGCAGGTCGTCTAC
GGCAAGGATTTGATCGCCGATATTCTGCCGCCGCCACTGTTTGTGGTGGAATCCTACATGCTGTCCTTCGAGGCGAGCAA
ATTTCCCGAGCTCACCGAAACCAATCTTGCCAAGATCGCAAATCTCAAGGCCGCCTACGACGACCGCCGCGCCTATTGGA
AAACCACCCGGCTGCCGCAGGCTTTGAAGGACGAGCTTGAAAACGATGTCATCGCCAAGGGCGATACATTCTGGGGGGTG
ATGAACCGTGAGATCATCCCGGCCCTGAATGCCAGGGATGAAGACAAGGCGCATGGTGCGATCGAGCAACTGCGCGTCGC
CTTTCATTCGCACCAGGATGCGGTCGAGAAACTCGTTGCCAATTCCGACGCCTTCCTGAAGGGCGAGGAGCGCAATGCAG
CCTCGGAGATCGTCACCTGGACGATCTATGCGGGTGCTGCGGGTCTCGGTTCGTTCGGGCTGTTGCTGGTGGGGCTCTAT
CTCCTGCGCCGCCGAGCAATCGTGCCGCTCGATGGCATGAAGGCCTATATGGGCAACCTTGCCGAAGGCGACTTTTCGAC
CGAAGTTCCCTACGCCAACCGGTCCGACGAGATCGGAGCCATGTCCAAGGCTGTGGCGGTATTCCGCCGCAACGCGCTCG
AGCGGCAGGAGGCGCAGAAGCGCGAGACCGCACTTCGCGATGCGGAATTTGAGCGCGAACGCAGCCAGCTGGCCGAAAGG
GCCGCAGAGGAGCAGATCCGCGAAACGGTGATCGATCGGTTGACATACGGCCTGGAACAGCTGTCGACCGGCAATCTCGA
TTGCCGGATCAAGACACCCTTCGCCGCCGCCTACGAGACTTTGCGCGCGAAGTTCAACGACAGTATGGACGCGCTTTGCG
CTTCGATGGCGGAGATCGCCCAGACCTCCAAGCAAGTGGGCAGTTCCTCGGCCGGCATCACCGATGCAGCCGACAGTCTT
GCGTCGCGCACGGAACAGCAGGCCGCAATGCTCGAAGAGGCGACAGCCGCGCTCGATGAAATGAATATTAAGGCCAAGGA
TGCCTCCGACCATGCCGGCAGGGCGACGGGCATGATGGCCGAGACCCGCACCAGCGCCGAACATTCGGCAGCCGTCGTTC
GCGAAGCCATCGCCGCCATGGAAAGGATCGAAGGTTCGTCCTCCCAGATCGGCGACATCGTCAATGTCATCGATGAAATC
GCCTTCCAGACCAATCTTCTGGCGCTCAATGCCGGGGTTGAAGCAGCGCGCGCCGGCGAAGCAGGCAAGGGTTTTGCCGT
CGTCGCGCAGGAAGTGCGCGAACTAGCCATGCGCTCGGCCAACGCCGCCAAGGAGATCAGATCTCTGATCTCCACCTCCT
CGGCGCAGGTCTCCACCGGTGTGGAGCTCGTCAACCGAACCGGCAAGGCGCTCCTGGAAATCGAAGGGCAGGTCGAGCAA
GTTGCCGGCCTGATCGCCCGCATCGTTTCGGTGTCTTCCGAGCAGGCGGTAGCGATCGGCGAGATCAACGCCTCCGTCAA
CGCGCTCGATCAGGTCACCCAGCGCAACGCAGCCATGGCGGTCGAAACTGCCTCGGCCTGCCGCGCCCTCGGTAGCCAGA
CACAGACACTGGAGGGGGTCGTCAACCGCTTTCAGGTCGATGCGGGAGCCAGCACGTCAAGGGCGCAAAAAGCTGCTTGA

Upstream 100 bases:

>100_bases
GTCGGTCTCCTTTCATCTGTATATACATCAGCCTGCCAGCCATCAAGATGGCAACTGATGGCTGGATACCACAAGTATTC
ACGACCCCTACTTTGTTCCG

Downstream 100 bases:

>100_bases
GGCAGCAGTCGAAACGGATCCCGCCTCTGCCTGTCCAATCACCTCAGCCCGTAACGATCGCCACGACGGCAACGCAGTCA
CCAGCCTTGACCAGCCCTGG

Product: putative methylation accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 639; Mature: 638

Protein sequence:

>639_residues
MPKELTISQCSCEIMPYVDQASRSREAKSYLEAVLALTIARSLVAFGVAVSAGLFMSIGLQQSALERLKVNGPVYEQVVY
GKDLIADILPPPLFVVESYMLSFEASKFPELTETNLAKIANLKAAYDDRRAYWKTTRLPQALKDELENDVIAKGDTFWGV
MNREIIPALNARDEDKAHGAIEQLRVAFHSHQDAVEKLVANSDAFLKGEERNAASEIVTWTIYAGAAGLGSFGLLLVGLY
LLRRRAIVPLDGMKAYMGNLAEGDFSTEVPYANRSDEIGAMSKAVAVFRRNALERQEAQKRETALRDAEFERERSQLAER
AAEEQIRETVIDRLTYGLEQLSTGNLDCRIKTPFAAAYETLRAKFNDSMDALCASMAEIAQTSKQVGSSSAGITDAADSL
ASRTEQQAAMLEEATAALDEMNIKAKDASDHAGRATGMMAETRTSAEHSAAVVREAIAAMERIEGSSSQIGDIVNVIDEI
AFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAMRSANAAKEIRSLISTSSAQVSTGVELVNRTGKALLEIEGQVEQ
VAGLIARIVSVSSEQAVAIGEINASVNALDQVTQRNAAMAVETASACRALGSQTQTLEGVVNRFQVDAGASTSRAQKAA

Sequences:

>Translated_639_residues
MPKELTISQCSCEIMPYVDQASRSREAKSYLEAVLALTIARSLVAFGVAVSAGLFMSIGLQQSALERLKVNGPVYEQVVY
GKDLIADILPPPLFVVESYMLSFEASKFPELTETNLAKIANLKAAYDDRRAYWKTTRLPQALKDELENDVIAKGDTFWGV
MNREIIPALNARDEDKAHGAIEQLRVAFHSHQDAVEKLVANSDAFLKGEERNAASEIVTWTIYAGAAGLGSFGLLLVGLY
LLRRRAIVPLDGMKAYMGNLAEGDFSTEVPYANRSDEIGAMSKAVAVFRRNALERQEAQKRETALRDAEFERERSQLAER
AAEEQIRETVIDRLTYGLEQLSTGNLDCRIKTPFAAAYETLRAKFNDSMDALCASMAEIAQTSKQVGSSSAGITDAADSL
ASRTEQQAAMLEEATAALDEMNIKAKDASDHAGRATGMMAETRTSAEHSAAVVREAIAAMERIEGSSSQIGDIVNVIDEI
AFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAMRSANAAKEIRSLISTSSAQVSTGVELVNRTGKALLEIEGQVEQ
VAGLIARIVSVSSEQAVAIGEINASVNALDQVTQRNAAMAVETASACRALGSQTQTLEGVVNRFQVDAGASTSRAQKAA
>Mature_638_residues
PKELTISQCSCEIMPYVDQASRSREAKSYLEAVLALTIARSLVAFGVAVSAGLFMSIGLQQSALERLKVNGPVYEQVVYG
KDLIADILPPPLFVVESYMLSFEASKFPELTETNLAKIANLKAAYDDRRAYWKTTRLPQALKDELENDVIAKGDTFWGVM
NREIIPALNARDEDKAHGAIEQLRVAFHSHQDAVEKLVANSDAFLKGEERNAASEIVTWTIYAGAAGLGSFGLLLVGLYL
LRRRAIVPLDGMKAYMGNLAEGDFSTEVPYANRSDEIGAMSKAVAVFRRNALERQEAQKRETALRDAEFERERSQLAERA
AEEQIRETVIDRLTYGLEQLSTGNLDCRIKTPFAAAYETLRAKFNDSMDALCASMAEIAQTSKQVGSSSAGITDAADSLA
SRTEQQAAMLEEATAALDEMNIKAKDASDHAGRATGMMAETRTSAEHSAAVVREAIAAMERIEGSSSQIGDIVNVIDEIA
FQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAMRSANAAKEIRSLISTSSAQVSTGVELVNRTGKALLEIEGQVEQV
AGLIARIVSVSSEQAVAIGEINASVNALDQVTQRNAAMAVETASACRALGSQTQTLEGVVNRFQVDAGASTSRAQKAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=267, Percent_Identity=43.4456928838951, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1788194, Length=290, Percent_Identity=37.9310344827586, Blast_Score=166, Evalue=5e-42,
Organism=Escherichia coli, GI2367378, Length=266, Percent_Identity=37.9699248120301, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1787690, Length=304, Percent_Identity=34.2105263157895, Blast_Score=152, Evalue=9e-38,
Organism=Escherichia coli, GI1789453, Length=246, Percent_Identity=38.2113821138211, Blast_Score=143, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 68734; Mature: 68603

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKELTISQCSCEIMPYVDQASRSREAKSYLEAVLALTIARSLVAFGVAVSAGLFMSIGL
CCCCCCHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QQSALERLKVNGPVYEQVVYGKDLIADILPPPLFVVESYMLSFEASKFPELTETNLAKIA
CHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
NLKAAYDDRRAYWKTTRLPQALKDELENDVIAKGDTFWGVMNREIIPALNARDEDKAHGA
HHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEECCCCHHHHHCCCHHCCCCCCCCHHHHHH
IEQLRVAFHSHQDAVEKLVANSDAFLKGEERNAASEIVTWTIYAGAAGLGSFGLLLVGLY
HHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHEEEEEECCCCCCHHHHHHHHHHH
LLRRRAIVPLDGMKAYMGNLAEGDFSTEVPYANRSDEIGAMSKAVAVFRRNALERQEAQK
HHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RETALRDAEFERERSQLAERAAEEQIRETVIDRLTYGLEQLSTGNLDCRIKTPFAAAYET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHH
LRAKFNDSMDALCASMAEIAQTSKQVGSSSAGITDAADSLASRTEQQAAMLEEATAALDE
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNIKAKDASDHAGRATGMMAETRTSAEHSAAVVREAIAAMERIEGSSSQIGDIVNVIDEI
CCCCCCCCCCCCCHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAMRSANAAKEIRSLISTSSAQVSTG
HHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHH
VELVNRTGKALLEIEGQVEQVAGLIARIVSVSSEQAVAIGEINASVNALDQVTQRNAAMA
HHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
VETASACRALGSQTQTLEGVVNRFQVDAGASTSRAQKAA
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHCCC
>Mature Secondary Structure 
PKELTISQCSCEIMPYVDQASRSREAKSYLEAVLALTIARSLVAFGVAVSAGLFMSIGL
CCCCCHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QQSALERLKVNGPVYEQVVYGKDLIADILPPPLFVVESYMLSFEASKFPELTETNLAKIA
CHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
NLKAAYDDRRAYWKTTRLPQALKDELENDVIAKGDTFWGVMNREIIPALNARDEDKAHGA
HHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEECCCCHHHHHCCCHHCCCCCCCCHHHHHH
IEQLRVAFHSHQDAVEKLVANSDAFLKGEERNAASEIVTWTIYAGAAGLGSFGLLLVGLY
HHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHEEEEEECCCCCCHHHHHHHHHHH
LLRRRAIVPLDGMKAYMGNLAEGDFSTEVPYANRSDEIGAMSKAVAVFRRNALERQEAQK
HHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RETALRDAEFERERSQLAERAAEEQIRETVIDRLTYGLEQLSTGNLDCRIKTPFAAAYET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHH
LRAKFNDSMDALCASMAEIAQTSKQVGSSSAGITDAADSLASRTEQQAAMLEEATAALDE
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNIKAKDASDHAGRATGMMAETRTSAEHSAAVVREAIAAMERIEGSSSQIGDIVNVIDEI
CCCCCCCCCCCCCHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAMRSANAAKEIRSLISTSSAQVSTG
HHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHH
VELVNRTGKALLEIEGQVEQVAGLIARIVSVSSEQAVAIGEINASVNALDQVTQRNAAMA
HHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
VETASACRALGSQTQTLEGVVNRFQVDAGASTSRAQKAA
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]