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The map label for this gene is thuF [C]

Identifier: 116248712

GI number: 116248712

Start: 35367

End: 36353

Strand: Direct

Name: thuF [C]

Synonym: pRL120036

Alternate gene names: 116248712

Gene position: 35367-36353 (Clockwise)

Preceding gene: 116248711

Following gene: 116248713

Centisome position: 4.07

GC content: 55.42

Gene sequence:

>987_bases
ATGAGCGAAATCGTAGTTCCACAAGCAGTCAAGCCCAGGGTTTCCCATTTCAGAGCCACCACGGAGTTGCGGTCCGAGCG
CATTCGATCGGCATGGATGTTTCTGGCGCCGACGCTGTTGATCTTGGCAATCGTCGCTGGCTGGCCGCTATTCAGAACGA
TCTATTTCAGTTTTACGAATGCGTCGCTGAACGACCTTGGCAATGCGCAGTTCGTCGGCTTTGACAATTATTTGTCGTGG
GTGACGCTGAAGAGCGGAAGGACCGTCTATCGCGGGCTGCTTGCCGATCCGGTCTGGTGGAATGCCGTCTGGAATACTGC
CAAGTTTACCGTCCTTTCGGTGGTAATCGAGACCGTACTAGGGCTGATCGTCGCCTTGGTGCTGAACGCACGGTTCGTCG
GGCGTGGGATCGTAAGGGCCGCAATCCTCATTCCTTGGGCGATCCCAACAATCGTCTCAGCAAAGATGTGGGCCTGGATG
CTCAATGATCAGTTCGGCATTCTGAACGATATTCTGCTCGGTTTCGGTCTTATCAGCGAGAAGATTGCCTGGACCGCCAA
TCTGGAAACGGCGATGATCGCAGTGCTGATCGTCGATGTCTGGAAGACGACGCCCTTCATGGCGCTTCTGATTCTTGCGG
GACTACAGATGGTTCCGGGAGACATCTATGAGGCTGCCAAGATCGACGGCGTCAATCCGGTCAAGGTTTTCTGGCGTCTG
ACGCTGCCGCTGATCCGACCGGCTATCATGGTTGCCGTGATCTTCCGGATGCTGGATGCAATGCGCATCTTCGACCTGAT
CTATGTTCTGACACCCAACAATGCGCAGACGAAGACCATGTCGGTCATGGCGCGCGAGAACCTGTTCGACTTCGACAAGT
TCGCCTACGGCGCCACCGCGTCAACGGTACTTTTCCTCATCATTGCCTCCGTAACCGTCCTTTATATCTGGCTCGGTCGC
GTCAAGCTCGGCGGGGAGGAACGTTGA

Upstream 100 bases:

>100_bases
CCTAACGACCCTCAAAGGCGACGCTTGGTGAGTATTCCGACCGGCGGCTGTCAGGCCGCCGGTCCGGTCTTCGGACGCGC
TAACGAGGGATAGACGTTTC

Downstream 100 bases:

>100_bases
TGCTGCTTTCGATCGCCAAAAATACGCTCTTCTACCTGCTCGTCACAATCATCGTCATCATTGCGGTATTTCCGTTCTAC
TATGCAATCCTCACGAGCCT

Product: putative permease component of ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSEIVVPQAVKPRVSHFRATTELRSERIRSAWMFLAPTLLILAIVAGWPLFRTIYFSFTNASLNDLGNAQFVGFDNYLSW
VTLKSGRTVYRGLLADPVWWNAVWNTAKFTVLSVVIETVLGLIVALVLNARFVGRGIVRAAILIPWAIPTIVSAKMWAWM
LNDQFGILNDILLGFGLISEKIAWTANLETAMIAVLIVDVWKTTPFMALLILAGLQMVPGDIYEAAKIDGVNPVKVFWRL
TLPLIRPAIMVAVIFRMLDAMRIFDLIYVLTPNNAQTKTMSVMARENLFDFDKFAYGATASTVLFLIIASVTVLYIWLGR
VKLGGEER

Sequences:

>Translated_328_residues
MSEIVVPQAVKPRVSHFRATTELRSERIRSAWMFLAPTLLILAIVAGWPLFRTIYFSFTNASLNDLGNAQFVGFDNYLSW
VTLKSGRTVYRGLLADPVWWNAVWNTAKFTVLSVVIETVLGLIVALVLNARFVGRGIVRAAILIPWAIPTIVSAKMWAWM
LNDQFGILNDILLGFGLISEKIAWTANLETAMIAVLIVDVWKTTPFMALLILAGLQMVPGDIYEAAKIDGVNPVKVFWRL
TLPLIRPAIMVAVIFRMLDAMRIFDLIYVLTPNNAQTKTMSVMARENLFDFDKFAYGATASTVLFLIIASVTVLYIWLGR
VKLGGEER
>Mature_327_residues
SEIVVPQAVKPRVSHFRATTELRSERIRSAWMFLAPTLLILAIVAGWPLFRTIYFSFTNASLNDLGNAQFVGFDNYLSWV
TLKSGRTVYRGLLADPVWWNAVWNTAKFTVLSVVIETVLGLIVALVLNARFVGRGIVRAAILIPWAIPTIVSAKMWAWML
NDQFGILNDILLGFGLISEKIAWTANLETAMIAVLIVDVWKTTPFMALLILAGLQMVPGDIYEAAKIDGVNPVKVFWRLT
LPLIRPAIMVAVIFRMLDAMRIFDLIYVLTPNNAQTKTMSVMARENLFDFDKFAYGATASTVLFLIIASVTVLYIWLGRV
KLGGEER

Specific function: Probably part of the binding-protein-dependent transport system y4oPQRS. This system probably transports a sugar-like molecule. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787570, Length=285, Percent_Identity=30.5263157894737, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1789861, Length=292, Percent_Identity=28.4246575342466, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790465, Length=236, Percent_Identity=26.271186440678, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36733; Mature: 36602

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIVVPQAVKPRVSHFRATTELRSERIRSAWMFLAPTLLILAIVAGWPLFRTIYFSFTN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
ASLNDLGNAQFVGFDNYLSWVTLKSGRTVYRGLLADPVWWNAVWNTAKFTVLSVVIETVL
CCHHHCCCEEEEEECCCEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GLIVALVLNARFVGRGIVRAAILIPWAIPTIVSAKMWAWMLNDQFGILNDILLGFGLISE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
KIAWTANLETAMIAVLIVDVWKTTPFMALLILAGLQMVPGDIYEAAKIDGVNPVKVFWRL
HHHEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHH
TLPLIRPAIMVAVIFRMLDAMRIFDLIYVLTPNNAQTKTMSVMARENLFDFDKFAYGATA
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCHHHHHCCCHH
STVLFLIIASVTVLYIWLGRVKLGGEER
HHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SEIVVPQAVKPRVSHFRATTELRSERIRSAWMFLAPTLLILAIVAGWPLFRTIYFSFTN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
ASLNDLGNAQFVGFDNYLSWVTLKSGRTVYRGLLADPVWWNAVWNTAKFTVLSVVIETVL
CCHHHCCCEEEEEECCCEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GLIVALVLNARFVGRGIVRAAILIPWAIPTIVSAKMWAWMLNDQFGILNDILLGFGLISE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
KIAWTANLETAMIAVLIVDVWKTTPFMALLILAGLQMVPGDIYEAAKIDGVNPVKVFWRL
HHHEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHH
TLPLIRPAIMVAVIFRMLDAMRIFDLIYVLTPNNAQTKTMSVMARENLFDFDKFAYGATA
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCHHHHHCCCHH
STVLFLIIASVTVLYIWLGRVKLGGEER
HHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]