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The map label for this gene is yneB [C]

Identifier: 116248703

GI number: 116248703

Start: 25903

End: 26703

Strand: Direct

Name: yneB [C]

Synonym: pRL120027

Alternate gene names: 116248703

Gene position: 25903-26703 (Clockwise)

Preceding gene: 116248701

Following gene: 116248704

Centisome position: 2.98

GC content: 64.29

Gene sequence:

>801_bases
ATGGGTCTCGGAACCAAAATCCGCCTCGCACGCCTGTTCTCGAACCCCTCGGGTCATCTGTTCGGAGGCGCCGTCGATCA
TTTTGTCGGTTATGGCAATGTGCGTGAGGGCGGGCTTGCCGACCTGCCCGGTGCGCTCAGACGCGTGATGGCGGGAGGCC
CCGACTATATCAGCATCCAGCCTGGCGCGGCGCGCCACCTGTGGTCGGAATATGCCGGAAAGGCAGCGCTGGTCATTCAG
GGTGGTTGCTTCACCGCCGACGACCGCATTCGTCAGCTCATTGCGACCCCGGAAGACGCGGTGCGTTATGGCGCGGACGC
TCTGGCTGTCGCCATTCCCGTGCGCGGCGCCACCGAAGGAGAGTATATCCGTTGGCTCACCGATACGGTCAACGCCGCCG
CCCGCTTCGAAATGCCGGTCGTCGCCCATGTCTATCCCCGCGATTTCTCCGACGGCGGCAAGATCGTGTTCACCCCGGAT
GAAATCGCTTACGCCGTGCGCATCGGCTTCGAGGCCGGCGTCGACGTGATCAAGGTCGGCTACACCGGCGATTTCGAGTC
CTTCCGCGAGACCGTTGCGACCTGCCCGATCCCGGTCGTGATCGCCGGTGGCCCGAAGACCGATACGCTGCTCGGAGCGC
TCGTCCAGACCTCGGAAGCATTGCGCGCAGGAGCCAAAGGCGCGGTCGTCGGTCGCAACCTTTGGGGTCACGGCGATACG
ACCATGGCCGCACGCGCCTTCAAATTCGTCATTCATAAAGGCATGACGCCGGAGGATGCGCTGGCGGCGGCCGGTGCTTG
A

Upstream 100 bases:

>100_bases
AGAAATCGAAATATTGAATATTTGTTTGTTTTCGAGTTAGGGTTTTGCCAGCATCGGCGCCAGCAATCGCAAAGGCTGCC
ATCACAAAGGAAGTATCGCC

Downstream 100 bases:

>100_bases
GAAGTGTCGCGCCCTTTCCAGGTTCTGGGCTTCGGTGCCCTGGCAATCGATGACATCATCTATGTCGATCGGGGGCTGAC
GGCCGGCAAGGGGAAGGTGA

Product: putative aldolase

Products: NA

Alternate protein names: ADH synthase; ADHS; Transaldolase-like ADHS [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MGLGTKIRLARLFSNPSGHLFGGAVDHFVGYGNVREGGLADLPGALRRVMAGGPDYISIQPGAARHLWSEYAGKAALVIQ
GGCFTADDRIRQLIATPEDAVRYGADALAVAIPVRGATEGEYIRWLTDTVNAAARFEMPVVAHVYPRDFSDGGKIVFTPD
EIAYAVRIGFEAGVDVIKVGYTGDFESFRETVATCPIPVVIAGGPKTDTLLGALVQTSEALRAGAKGAVVGRNLWGHGDT
TMAARAFKFVIHKGMTPEDALAAAGA

Sequences:

>Translated_266_residues
MGLGTKIRLARLFSNPSGHLFGGAVDHFVGYGNVREGGLADLPGALRRVMAGGPDYISIQPGAARHLWSEYAGKAALVIQ
GGCFTADDRIRQLIATPEDAVRYGADALAVAIPVRGATEGEYIRWLTDTVNAAARFEMPVVAHVYPRDFSDGGKIVFTPD
EIAYAVRIGFEAGVDVIKVGYTGDFESFRETVATCPIPVVIAGGPKTDTLLGALVQTSEALRAGAKGAVVGRNLWGHGDT
TMAARAFKFVIHKGMTPEDALAAAGA
>Mature_265_residues
GLGTKIRLARLFSNPSGHLFGGAVDHFVGYGNVREGGLADLPGALRRVMAGGPDYISIQPGAARHLWSEYAGKAALVIQG
GCFTADDRIRQLIATPEDAVRYGADALAVAIPVRGATEGEYIRWLTDTVNAAARFEMPVVAHVYPRDFSDGGKIVFTPDE
IAYAVRIGFEAGVDVIKVGYTGDFESFRETVATCPIPVVIAGGPKTDTLLGALVQTSEALRAGAKGAVVGRNLWGHGDTT
MAARAFKFVIHKGMTPEDALAAAGA

Specific function: Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH). Plays a key role

COG id: COG1830

COG function: function code G; DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. ADHS subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787796, Length=259, Percent_Identity=25.8687258687259, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR010210
- InterPro:   IPR002915 [H]

Pfam domain/function: PF01791 DeoC [H]

EC number: 4.2.1.- [C]

Molecular weight: Translated: 27973; Mature: 27842

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLGTKIRLARLFSNPSGHLFGGAVDHFVGYGNVREGGLADLPGALRRVMAGGPDYISIQ
CCCCCCEEEEEECCCCCCCEECCHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEC
PGAARHLWSEYAGKAALVIQGGCFTADDRIRQLIATPEDAVRYGADALAVAIPVRGATEG
CCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHCCCEEEEEEECCCCCCC
EYIRWLTDTVNAAARFEMPVVAHVYPRDFSDGGKIVFTPDEIAYAVRIGFEAGVDVIKVG
CEEEHHHHHHHHHHEECCCEEEEECCCCCCCCCEEEECCHHEEEEEEECHHCCCEEEEEC
YTGDFESFRETVATCPIPVVIAGGPKTDTLLGALVQTSEALRAGAKGAVVGRNLWGHGDT
CCCCHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCH
TMAARAFKFVIHKGMTPEDALAAAGA
HHHHHHHHHHHHCCCCCHHHHHCCCC
>Mature Secondary Structure 
GLGTKIRLARLFSNPSGHLFGGAVDHFVGYGNVREGGLADLPGALRRVMAGGPDYISIQ
CCCCCEEEEEECCCCCCCEECCHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEC
PGAARHLWSEYAGKAALVIQGGCFTADDRIRQLIATPEDAVRYGADALAVAIPVRGATEG
CCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHCCCEEEEEEECCCCCCC
EYIRWLTDTVNAAARFEMPVVAHVYPRDFSDGGKIVFTPDEIAYAVRIGFEAGVDVIKVG
CEEEHHHHHHHHHHEECCCEEEEECCCCCCCCCEEEECCHHEEEEEEECHHCCCEEEEEC
YTGDFESFRETVATCPIPVVIAGGPKTDTLLGALVQTSEALRAGAKGAVVGRNLWGHGDT
CCCCHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCH
TMAARAFKFVIHKGMTPEDALAAAGA
HHHHHHHHHHHHCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]