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The map label for this gene is rhtC [H]

Identifier: 115353148

GI number: 115353148

Start: 3418514

End: 3419161

Strand: Direct

Name: rhtC [H]

Synonym: Bamb_3097

Alternate gene names: 115353148

Gene position: 3418514-3419161 (Clockwise)

Preceding gene: 115353147

Following gene: 115353149

Centisome position: 96.12

GC content: 70.68

Gene sequence:

>648_bases
ATGAACTACCTGCCGATCCTGCTGCAAATCGCCGTCGTCTATCTCGTCGCGGCGATCACGCCCGGCCCGAACTTCTTCAT
GATTTCGCAGTTGTCGCTCGCGGGGCGGCGCAGCCTCGGCGCGGCGTCGGCACTCGGCGTCGGCACCGCATCGATGGCCT
GGGCGACGCTCGCGATGCTCGGCCTCGCGGCCGTCCTGCACCAGGTCGAATGGCTGTACGAGACGATCCGGATCGGCGGC
GCCGTCTATCTCGTGTATTTCGGCATCAAGCTGCTGCGCTCGGGCGTGCGCCGCGACGCGGCGCCGGCAGACACCGCGGA
TGTGAGCGCGCCGCTGGCCGCGCCGCGCCTGCGCGACTATCTGCGTGCGTATCGCAGCGGCCTGCTCACCTGCCTGACCA
ACCCGAAATCGTGCGCGTTCTGGACCAGCGTGTTCGCGGCGATGCTGCCCGCGCACGTGCCGCTGTGGTTCAACGGCGCG
GTGCTGGTGACGATCGGCGTGCTGTCGGCCGGCTGGTATTCGTGCGTGGCGTTCCTGTTCGCGAGCCCGCGCGCGCAGCG
CGGCTACCGGCGCGTGCGGCGCCCGCTCGACGCGCTGTGCGGCGTCGCGCTCGTCGGCCTCGGCGCGAAGCTCGCGGCCG
ATCGTTGA

Upstream 100 bases:

>100_bases
GCACCCTTGAAGCGCTGACGCCCTTGAAGCCCTGACACCGCAAGCGCGGTTGCACGGCGCGCGCTACAGTAACGCTTTGC
CCGCCTGCCACCCCGCCGCG

Downstream 100 bases:

>100_bases
AAGCTCGCTGAAATGATTCGTTGCGCCAAATCCGCGCAGCCGGGCGGGTCAAGCCCGCATCTGTCCCAAGCAGGGTAAAA
TAACCAGTTCCTCAAACGTC

Product: lysine exporter protein LysE/YggA

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MNYLPILLQIAVVYLVAAITPGPNFFMISQLSLAGRRSLGAASALGVGTASMAWATLAMLGLAAVLHQVEWLYETIRIGG
AVYLVYFGIKLLRSGVRRDAAPADTADVSAPLAAPRLRDYLRAYRSGLLTCLTNPKSCAFWTSVFAAMLPAHVPLWFNGA
VLVTIGVLSAGWYSCVAFLFASPRAQRGYRRVRRPLDALCGVALVGLGAKLAADR

Sequences:

>Translated_215_residues
MNYLPILLQIAVVYLVAAITPGPNFFMISQLSLAGRRSLGAASALGVGTASMAWATLAMLGLAAVLHQVEWLYETIRIGG
AVYLVYFGIKLLRSGVRRDAAPADTADVSAPLAAPRLRDYLRAYRSGLLTCLTNPKSCAFWTSVFAAMLPAHVPLWFNGA
VLVTIGVLSAGWYSCVAFLFASPRAQRGYRRVRRPLDALCGVALVGLGAKLAADR
>Mature_215_residues
MNYLPILLQIAVVYLVAAITPGPNFFMISQLSLAGRRSLGAASALGVGTASMAWATLAMLGLAAVLHQVEWLYETIRIGG
AVYLVYFGIKLLRSGVRRDAAPADTADVSAPLAAPRLRDYLRAYRSGLLTCLTNPKSCAFWTSVFAAMLPAHVPLWFNGA
VLVTIGVLSAGWYSCVAFLFASPRAQRGYRRVRRPLDALCGVALVGLGAKLAADR

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=212, Percent_Identity=33.4905660377358, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI1786522, Length=197, Percent_Identity=29.9492385786802, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1788099, Length=208, Percent_Identity=26.9230769230769, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23001; Mature: 23001

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYLPILLQIAVVYLVAAITPGPNFFMISQLSLAGRRSLGAASALGVGTASMAWATLAML
CCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHH
GLAAVLHQVEWLYETIRIGGAVYLVYFGIKLLRSGVRRDAAPADTADVSAPLAAPRLRDY
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
LRAYRSGLLTCLTNPKSCAFWTSVFAAMLPAHVPLWFNGAVLVTIGVLSAGWYSCVAFLF
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHH
ASPRAQRGYRRVRRPLDALCGVALVGLGAKLAADR
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MNYLPILLQIAVVYLVAAITPGPNFFMISQLSLAGRRSLGAASALGVGTASMAWATLAML
CCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHH
GLAAVLHQVEWLYETIRIGGAVYLVYFGIKLLRSGVRRDAAPADTADVSAPLAAPRLRDY
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
LRAYRSGLLTCLTNPKSCAFWTSVFAAMLPAHVPLWFNGAVLVTIGVLSAGWYSCVAFLF
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHH
ASPRAQRGYRRVRRPLDALCGVALVGLGAKLAADR
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]