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The map label for this gene is pcpR [H]

Identifier: 115352505

GI number: 115352505

Start: 2700631

End: 2701659

Strand: Direct

Name: pcpR [H]

Synonym: Bamb_2454

Alternate gene names: 115352505

Gene position: 2700631-2701659 (Clockwise)

Preceding gene: 115352503

Following gene: 115352506

Centisome position: 75.93

GC content: 69.48

Gene sequence:

>1029_bases
ATGCGGCGCGGCCCGCGCACATGCGCGTGGCGGCGGTCAGATCCACATGCTACGTTCCCGTCTCAACTGCAGGAAGTGCA
GTTTCTTCATCTGGACATGAACATGATGCATCCCGATTTGCGCCGTCTCGACCTGAACCTGCTGCTCGCGTTCGACGCGC
TGTACCGCCACCGGTCGGTGGCCGCGGCCGCGCACGAACTGGCGATGAGCCCGTCCGCGCTGAGTCACGCGCTCGCGCGG
CTGCGCGACGCGATCGGCGACGCGCTGTTCGTGCGGCTCGGCAACGAGATGCAGCCGACCGTGCGCGCCGACGACATCGC
CACCTGGGCCGGCGACGCGCTCGACACGATGTCGAAGGGGCTCGCCCGCGCGCGCCGCTTCGATCCCGCGCAAAGCGACC
GCACGTTCGTGTTCGCCGCGAGCGACTACACGGCGTTCGCCGTGCTGCCGGCCTTGCTCGCGCGCATCGAGCGGGTCGCG
CCGCGGCTGCGGATCCGCGTCGTCCATTCCGAGCGCAAGATTTCGATCGACGAGCTCGCGGCCGGCCGCATCGATTTCGC
GCTCGGCTATCACGAGGAGTCGACCGCCGACTCGCCGGGCATCGAGGATTTCGACTGGTTCTCGGACGACTACGTGGTGA
TTGCGAGCGCCGCGCATCCGGACATCCGCCGGCGGCTGACGCTGGACCAGTATCTCGCGGCACGCCACGTGGTCGTCACG
CCGTGGAACGAGTCGCGCGGCGTCGTCGACTACGTGCTCGACCGGCTCGGCCTCGCGCGGCAGGTCGCCGTGCGGCTGCC
GAGCGTGCTGGCCGCACCGTTCGCGATCGCGGAATCGACGCTGCTGATGACGGTGCCGAACCGCGCCGCCCAGGCGCTGC
GTCACGCGGCGCCGATCCGCATCTTCCCCGCGCCGTTCGAGATCCCGCGCTATACGGTGAAGGTCTACTCGCACGCGAAG
CACGCACGCACCGATGCGCACCGATGGATCCGCGCGCAATTGCTCGATGCCCGACCCGCGCAGGGTTGA

Upstream 100 bases:

>100_bases
GGTGATGAAGCGCAGGATTTGCGGGACGTCGGCGACGGTGGCGCAACGGATGTCGATTTGCACGGCGGGGAGCCCTCCTT
CGGCCCGGACGGGAAACGGA

Downstream 100 bases:

>100_bases
GCCGGGCGCGCTTGTCCGGCGGTCGATGGCCCCAGTGTCAGAGCCATTGCAGAGGCGGCCCGGCGCCGTTGGGCCATGCC
GAATTTATTACGAAATACTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MRRGPRTCAWRRSDPHATFPSQLQEVQFLHLDMNMMHPDLRRLDLNLLLAFDALYRHRSVAAAAHELAMSPSALSHALAR
LRDAIGDALFVRLGNEMQPTVRADDIATWAGDALDTMSKGLARARRFDPAQSDRTFVFAASDYTAFAVLPALLARIERVA
PRLRIRVVHSERKISIDELAAGRIDFALGYHEESTADSPGIEDFDWFSDDYVVIASAAHPDIRRRLTLDQYLAARHVVVT
PWNESRGVVDYVLDRLGLARQVAVRLPSVLAAPFAIAESTLLMTVPNRAAQALRHAAPIRIFPAPFEIPRYTVKVYSHAK
HARTDAHRWIRAQLLDARPAQG

Sequences:

>Translated_342_residues
MRRGPRTCAWRRSDPHATFPSQLQEVQFLHLDMNMMHPDLRRLDLNLLLAFDALYRHRSVAAAAHELAMSPSALSHALAR
LRDAIGDALFVRLGNEMQPTVRADDIATWAGDALDTMSKGLARARRFDPAQSDRTFVFAASDYTAFAVLPALLARIERVA
PRLRIRVVHSERKISIDELAAGRIDFALGYHEESTADSPGIEDFDWFSDDYVVIASAAHPDIRRRLTLDQYLAARHVVVT
PWNESRGVVDYVLDRLGLARQVAVRLPSVLAAPFAIAESTLLMTVPNRAAQALRHAAPIRIFPAPFEIPRYTVKVYSHAK
HARTDAHRWIRAQLLDARPAQG
>Mature_342_residues
MRRGPRTCAWRRSDPHATFPSQLQEVQFLHLDMNMMHPDLRRLDLNLLLAFDALYRHRSVAAAAHELAMSPSALSHALAR
LRDAIGDALFVRLGNEMQPTVRADDIATWAGDALDTMSKGLARARRFDPAQSDRTFVFAASDYTAFAVLPALLARIERVA
PRLRIRVVHSERKISIDELAAGRIDFALGYHEESTADSPGIEDFDWFSDDYVVIASAAHPDIRRRLTLDQYLAARHVVVT
PWNESRGVVDYVLDRLGLARQVAVRLPSVLAAPFAIAESTLLMTVPNRAAQALRHAAPIRIFPAPFEIPRYTVKVYSHAK
HARTDAHRWIRAQLLDARPAQG

Specific function: Transcriptional activator for the pcpA, pcpB and pcpE genes for pentachlorophenol (PCP) degradation. Essential for PCP degradation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=307, Percent_Identity=27.3615635179153, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI87081766, Length=272, Percent_Identity=24.6323529411765, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790147, Length=270, Percent_Identity=27.037037037037, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786820, Length=62, Percent_Identity=46.7741935483871, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 38370; Mature: 38370

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRGPRTCAWRRSDPHATFPSQLQEVQFLHLDMNMMHPDLRRLDLNLLLAFDALYRHRSV
CCCCCCCCEECCCCCCCCCHHHHHHHHHHEECHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AAAAHELAMSPSALSHALARLRDAIGDALFVRLGNEMQPTVRADDIATWAGDALDTMSKG
HHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEHCCCCCCCCCCCCHHHHHCCHHHHHHHHH
LARARRFDPAQSDRTFVFAASDYTAFAVLPALLARIERVAPRLRIRVVHSERKISIDELA
HHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHH
AGRIDFALGYHEESTADSPGIEDFDWFSDDYVVIASAAHPDIRRRLTLDQYLAARHVVVT
CCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEE
PWNESRGVVDYVLDRLGLARQVAVRLPSVLAAPFAIAESTLLMTVPNRAAQALRHAAPIR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHCCCCE
IFPAPFEIPRYTVKVYSHAKHARTDAHRWIRAQLLDARPAQG
EECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRRGPRTCAWRRSDPHATFPSQLQEVQFLHLDMNMMHPDLRRLDLNLLLAFDALYRHRSV
CCCCCCCCEECCCCCCCCCHHHHHHHHHHEECHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AAAAHELAMSPSALSHALARLRDAIGDALFVRLGNEMQPTVRADDIATWAGDALDTMSKG
HHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEHCCCCCCCCCCCCHHHHHCCHHHHHHHHH
LARARRFDPAQSDRTFVFAASDYTAFAVLPALLARIERVAPRLRIRVVHSERKISIDELA
HHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHH
AGRIDFALGYHEESTADSPGIEDFDWFSDDYVVIASAAHPDIRRRLTLDQYLAARHVVVT
CCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEE
PWNESRGVVDYVLDRLGLARQVAVRLPSVLAAPFAIAESTLLMTVPNRAAQALRHAAPIR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHCCCCE
IFPAPFEIPRYTVKVYSHAKHARTDAHRWIRAQLLDARPAQG
EECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12169590 [H]