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The map label for this gene is can [H]

Identifier: 115352347

GI number: 115352347

Start: 2531903

End: 2532544

Strand: Direct

Name: can [H]

Synonym: Bamb_2296

Alternate gene names: 115352347

Gene position: 2531903-2532544 (Clockwise)

Preceding gene: 115352345

Following gene: 115352348

Centisome position: 71.19

GC content: 71.34

Gene sequence:

>642_bases
ATGAACCGCCCCAAGAGCATGCTGGTTGCCAACATCGCCTGGGCCCGCGAGACGCGCGATCACACGCCCGGCTTCTTCGA
CGCGCTTGCACGCGGCCAGAACCCGCGCGTGCTGTGGATCGGCTGCGCCGACAGCCGGGTGCCGGCCGAAACCATCACGC
ACAGCGTGCCCGGCGAGCTGTTCGTCCATCGCAACATCGCCAACCTGTTCCATCCCGACGATGACAATTCGGCCAGCGTG
CTCGAATACGCGGTGCGCGTGCTCGAAGTCGACCACGTGATCGTGTGCGGCCACTACGGGTGCGGCGGCGTGCGCGCGTC
GCTGCTGCCGCCGCCCGCCGACCTGCCGCACGTCGCGCGCCGCATCGCGCCGCTTTGCGCGCTCGCGCGACGCCATCGCG
ACGCGCTCGACGGACTCGACGACACGGCCGCCGCCGACCGCCTGGCCGAGCTGAACGTGCTCGAACAGGTGCGGCTGCTG
CGCGCGTCGCCGATCGTGCAAGGCCGGAAGCGGCCGCCGCTCGTGCACGGCTGGATCTTCTCTCTCGCCGACGGCCTCCT
GAAGGAACTCGACTCCGGCTATGCGGCGCCGCCGGCCGAACCCGAACCGGAGCATGCCGCCACGGCCGCCGCAGCCGCCT
GA

Upstream 100 bases:

>100_bases
TCAGTCGAAATTGAACCTTTCAGTTCAGAAAGGATCCTATTGCTCCACATCGTCCCGTCTTTGTTTGCCATTTGTTTTCC
TTTATCGGAAAGGAGTCCTT

Downstream 100 bases:

>100_bases
CCCGCGCCCTTCCCCAACGCTACGAAATCGCCCAACCATGAAACTGAACGAGCGCCTGTCCACCCTGCCGCGCGACATCG
TCGCCGGCATCGTCGTTTTC

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MNRPKSMLVANIAWARETRDHTPGFFDALARGQNPRVLWIGCADSRVPAETITHSVPGELFVHRNIANLFHPDDDNSASV
LEYAVRVLEVDHVIVCGHYGCGGVRASLLPPPADLPHVARRIAPLCALARRHRDALDGLDDTAAADRLAELNVLEQVRLL
RASPIVQGRKRPPLVHGWIFSLADGLLKELDSGYAAPPAEPEPEHAATAAAAA

Sequences:

>Translated_213_residues
MNRPKSMLVANIAWARETRDHTPGFFDALARGQNPRVLWIGCADSRVPAETITHSVPGELFVHRNIANLFHPDDDNSASV
LEYAVRVLEVDHVIVCGHYGCGGVRASLLPPPADLPHVARRIAPLCALARRHRDALDGLDDTAAADRLAELNVLEQVRLL
RASPIVQGRKRPPLVHGWIFSLADGLLKELDSGYAAPPAEPEPEHAATAAAAA
>Mature_213_residues
MNRPKSMLVANIAWARETRDHTPGFFDALARGQNPRVLWIGCADSRVPAETITHSVPGELFVHRNIANLFHPDDDNSASV
LEYAVRVLEVDHVIVCGHYGCGGVRASLLPPPADLPHVARRIAPLCALARRHRDALDGLDDTAAADRLAELNVLEQVRLL
RASPIVQGRKRPPLVHGWIFSLADGLLKELDSGYAAPPAEPEPEHAATAAAAA

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=194, Percent_Identity=44.8453608247423, Blast_Score=170, Evalue=7e-44,
Organism=Escherichia coli, GI1786534, Length=201, Percent_Identity=31.3432835820896, Blast_Score=86, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324292, Length=209, Percent_Identity=30.1435406698565, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 23062; Mature: 23062

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRPKSMLVANIAWARETRDHTPGFFDALARGQNPRVLWIGCADSRVPAETITHSVPGEL
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCCCCE
FVHRNIANLFHPDDDNSASVLEYAVRVLEVDHVIVCGHYGCGGVRASLLPPPADLPHVAR
EEEHHHHHHCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCCHHHHHH
RIAPLCALARRHRDALDGLDDTAAADRLAELNVLEQVRLLRASPIVQGRKRPPLVHGWIF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCHHHHHHH
SLADGLLKELDSGYAAPPAEPEPEHAATAAAAA
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MNRPKSMLVANIAWARETRDHTPGFFDALARGQNPRVLWIGCADSRVPAETITHSVPGEL
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCCCCE
FVHRNIANLFHPDDDNSASVLEYAVRVLEVDHVIVCGHYGCGGVRASLLPPPADLPHVAR
EEEHHHHHHCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCCHHHHHH
RIAPLCALARRHRDALDGLDDTAAADRLAELNVLEQVRLLRASPIVQGRKRPPLVHGWIF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCHHHHHHH
SLADGLLKELDSGYAAPPAEPEPEHAATAAAAA
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]