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The map label for this gene is argA [H]

Identifier: 115352244

GI number: 115352244

Start: 2416966

End: 2418345

Strand: Direct

Name: argA [H]

Synonym: Bamb_2193

Alternate gene names: 115352244

Gene position: 2416966-2418345 (Clockwise)

Preceding gene: 115352238

Following gene: 115352245

Centisome position: 67.96

GC content: 66.88

Gene sequence:

>1380_bases
ATGAATTCCCAAACCGACCTCCCTCCCGCCCAGACCGGCGCCGCGACGCCGCCGGCTGCCGACGATTCGGCCGCCAGCCA
CGCGCAGTTCGTCGACTGGATGCGCTCCGTCGCGCCCTATATCCACAAGTTCCGCAACAGCACGTTCGTCGTGGGGTTCG
GCGGCGAGGTGGTGCAGCAGGGACTCCTGAACGCGCTCGTGTCCGACATCGCGCTGCTGCAGGCGATGGGCATCCAGATC
GTGCTGGTGCACGGCTCGCGCCCGCAGGTCGAGGAGCAGCTGAGCCTGCATGGTGTCGAATCCGAGTTTTCGCACGGGCT
GCGCATCACCGATGCGCGCGCGCTCGAATCCGCGAAGGAAGCGGCCGGCGAAGTGCGTCTCGACATCGAGGCCGCGATCA
GCCAGGGTCTGCCGAACTCGCCGATGGCGCACGCGCACATCAGCGTCGTGTCCGGCAACTTCGTGACCGCACGACCGGTG
GGGATTCTCGACGGGGTCGATTTCGCGCACACGGGCATCGTGCGCAAGATCGACGCCGAATCGATCCGTCATTCGCTCGC
GAGCCGCAAGCTCGTGCTGCTGTCGCCGCTCGGTTTCTCGCCGACCGGCGAAGCGTTCAACCTGTCGATGGAAGACGTCG
CGTCGGCGGCCGCGATCGCGCTGCGCGCCGACAAGATCATCTTCCTGACCGAGGCGCCCGGCATCGTCGGCGACGAAGGC
GAGCTGGTCCGTGAAATGTCGCTCGACGCGGCCGCCGAGCTGCTCGATTCCGGCAACGTCCAGGGCGACGACGCGTTCTT
CCTGAAGCATTCGATCCGCGCGTGCCGCGGCGGCGTGACCCGTGCCCACCTGATCCCGCAATCGCTCGACGGCAGCATGC
TGCTCGAACTGTTCCTGCACGACGGCGTCGGCACGATGATCTCGTACGAGAATCTCGAGAGCCTGCGCGAAGCGACGCCG
GACGACGTCGGCGGCATCCTGTCGCTGATCGAGCCGCTCGAGTCGGACGGCACGCTGGTGCGACGCGGCCGCCACCAGAT
CGAACGCGACATCGACCACTTCTCGGTGATCGAGCACGATGGCGTGCTGTTCGGCTGCGCGGCGCTGTATCCGTACCAGC
AGGAAAAGATCGGCGAGATGGCGTGCCTGACGGTCGCGCCGGAAGCGCAGGGCTCGGGCGACGGCGAACGCCTGCTCAAG
CGCATCGAGCAGCGCGCCCGCGCGCGCGGCCTCACGCATATCTTCGTGCTCACGACGCGCACCGAGCACTGGTTCCTCAA
GCGCGGCTTCGTCAAGGTCAGCGTCGACGACCTGCCGGAAGACCGCCGCAAACTCTATAACTGGCAGCGCAAGTCGCTCG
TGCTGATGAAGCAGCTCTGA

Upstream 100 bases:

>100_bases
TCGGCCGCACCATCCGGGTGCCGCGCCGACGGCGCTTTGGCCCGCGTCGGCGCGGGACTTTTAGGTACATTCGACATGGG
GGCGCATTATAATCCCGCCC

Downstream 100 bases:

>100_bases
GCGCAGGCACGACTGCCCTCCCCCAGTCCGATTACAGGAGAAGTACACGATGGCTCGAATGATTCAATGCGCGAAGCTCG
GCAAGGAAGCCGAGGCTCTC

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MNSQTDLPPAQTGAATPPAADDSAASHAQFVDWMRSVAPYIHKFRNSTFVVGFGGEVVQQGLLNALVSDIALLQAMGIQI
VLVHGSRPQVEEQLSLHGVESEFSHGLRITDARALESAKEAAGEVRLDIEAAISQGLPNSPMAHAHISVVSGNFVTARPV
GILDGVDFAHTGIVRKIDAESIRHSLASRKLVLLSPLGFSPTGEAFNLSMEDVASAAAIALRADKIIFLTEAPGIVGDEG
ELVREMSLDAAAELLDSGNVQGDDAFFLKHSIRACRGGVTRAHLIPQSLDGSMLLELFLHDGVGTMISYENLESLREATP
DDVGGILSLIEPLESDGTLVRRGRHQIERDIDHFSVIEHDGVLFGCAALYPYQQEKIGEMACLTVAPEAQGSGDGERLLK
RIEQRARARGLTHIFVLTTRTEHWFLKRGFVKVSVDDLPEDRRKLYNWQRKSLVLMKQL

Sequences:

>Translated_459_residues
MNSQTDLPPAQTGAATPPAADDSAASHAQFVDWMRSVAPYIHKFRNSTFVVGFGGEVVQQGLLNALVSDIALLQAMGIQI
VLVHGSRPQVEEQLSLHGVESEFSHGLRITDARALESAKEAAGEVRLDIEAAISQGLPNSPMAHAHISVVSGNFVTARPV
GILDGVDFAHTGIVRKIDAESIRHSLASRKLVLLSPLGFSPTGEAFNLSMEDVASAAAIALRADKIIFLTEAPGIVGDEG
ELVREMSLDAAAELLDSGNVQGDDAFFLKHSIRACRGGVTRAHLIPQSLDGSMLLELFLHDGVGTMISYENLESLREATP
DDVGGILSLIEPLESDGTLVRRGRHQIERDIDHFSVIEHDGVLFGCAALYPYQQEKIGEMACLTVAPEAQGSGDGERLLK
RIEQRARARGLTHIFVLTTRTEHWFLKRGFVKVSVDDLPEDRRKLYNWQRKSLVLMKQL
>Mature_459_residues
MNSQTDLPPAQTGAATPPAADDSAASHAQFVDWMRSVAPYIHKFRNSTFVVGFGGEVVQQGLLNALVSDIALLQAMGIQI
VLVHGSRPQVEEQLSLHGVESEFSHGLRITDARALESAKEAAGEVRLDIEAAISQGLPNSPMAHAHISVVSGNFVTARPV
GILDGVDFAHTGIVRKIDAESIRHSLASRKLVLLSPLGFSPTGEAFNLSMEDVASAAAIALRADKIIFLTEAPGIVGDEG
ELVREMSLDAAAELLDSGNVQGDDAFFLKHSIRACRGGVTRAHLIPQSLDGSMLLELFLHDGVGTMISYENLESLREATP
DDVGGILSLIEPLESDGTLVRRGRHQIERDIDHFSVIEHDGVLFGCAALYPYQQEKIGEMACLTVAPEAQGSGDGERLLK
RIEQRARARGLTHIFVLTTRTEHWFLKRGFVKVSVDDLPEDRRKLYNWQRKSLVLMKQL

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=436, Percent_Identity=45.8715596330275, Blast_Score=418, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6320913, Length=285, Percent_Identity=26.3157894736842, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 49868; Mature: 49868

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSQTDLPPAQTGAATPPAADDSAASHAQFVDWMRSVAPYIHKFRNSTFVVGFGGEVVQQ
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHH
GLLNALVSDIALLQAMGIQIVLVHGSRPQVEEQLSLHGVESEFSHGLRITDARALESAKE
HHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHCCCHHHHHCCCEEEHHHHHHHHHH
AAGEVRLDIEAAISQGLPNSPMAHAHISVVSGNFVTARPVGILDGVDFAHTGIVRKIDAE
HCCCEEEEHHHHHHCCCCCCCCCEEEEEEEECCEEEECCCCEECCCCHHHCCHHHCCCHH
SIRHSLASRKLVLLSPLGFSPTGEAFNLSMEDVASAAAIALRADKIIFLTEAPGIVGDEG
HHHHHHHHCCEEEEECCCCCCCCCEEECCHHHHHHHHHHEEECCEEEEEECCCCCCCCCH
ELVREMSLDAAAELLDSGNVQGDDAFFLKHSIRACRGGVTRAHLIPQSLDGSMLLELFLH
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEHCCCCCCCHHHHHHHHHH
DGVGTMISYENLESLREATPDDVGGILSLIEPLESDGTLVRRGRHQIERDIDHFSVIEHD
CCCCHHEEHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHEECC
GVLFGCAALYPYQQEKIGEMACLTVAPEAQGSGDGERLLKRIEQRARARGLTHIFVLTTR
CEEEEHHHHCCCCHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEC
TEHWFLKRGFVKVSVDDLPEDRRKLYNWQRKSLVLMKQL
CHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSQTDLPPAQTGAATPPAADDSAASHAQFVDWMRSVAPYIHKFRNSTFVVGFGGEVVQQ
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHH
GLLNALVSDIALLQAMGIQIVLVHGSRPQVEEQLSLHGVESEFSHGLRITDARALESAKE
HHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHCCCHHHHHCCCEEEHHHHHHHHHH
AAGEVRLDIEAAISQGLPNSPMAHAHISVVSGNFVTARPVGILDGVDFAHTGIVRKIDAE
HCCCEEEEHHHHHHCCCCCCCCCEEEEEEEECCEEEECCCCEECCCCHHHCCHHHCCCHH
SIRHSLASRKLVLLSPLGFSPTGEAFNLSMEDVASAAAIALRADKIIFLTEAPGIVGDEG
HHHHHHHHCCEEEEECCCCCCCCCEEECCHHHHHHHHHHEEECCEEEEEECCCCCCCCCH
ELVREMSLDAAAELLDSGNVQGDDAFFLKHSIRACRGGVTRAHLIPQSLDGSMLLELFLH
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEHCCCCCCCHHHHHHHHHH
DGVGTMISYENLESLREATPDDVGGILSLIEPLESDGTLVRRGRHQIERDIDHFSVIEHD
CCCCHHEEHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHEECC
GVLFGCAALYPYQQEKIGEMACLTVAPEAQGSGDGERLLKRIEQRARARGLTHIFVLTTR
CEEEEHHHHCCCCHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEC
TEHWFLKRGFVKVSVDDLPEDRRKLYNWQRKSLVLMKQL
CHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]