Click here to switch to the map view.

The map label for this gene is cobL [H]

Identifier: 115351628

GI number: 115351628

Start: 1743048

End: 1744283

Strand: Direct

Name: cobL [H]

Synonym: Bamb_1575

Alternate gene names: 115351628

Gene position: 1743048-1744283 (Clockwise)

Preceding gene: 115351621

Following gene: 115351629

Centisome position: 49.01

GC content: 75.08

Gene sequence:

>1236_bases
ATGACGGCGTGGCTGACGGTAGTGGGCATCGGCGACGACGGTTACGCGGGGCTCGGGCGCAGCGCGCGGCGCGCGCTGCT
CGACGCGACGCGGGTCGTCGGCGCGAAGCGGCACCTCGACATGCTGCCCGCGCGGCTGCGGGCCGCGCGCGAGCCATGGC
CGTCGCCGTTCGACGTGTCGGGCCTGCTCGCGCGACGCGACGCGCCCGTCTGCGTGCTGGCAAGCGGCGACCCGATGCTG
TTCGGCGTCGGCGCCACGCTCGCGCGCGAGCTATCCCCAGACGAATGGCGCGTGCTGCCCGCCCCGTCGTCGCTGTCGCT
GGCGGCCGCACGGCTCGGCTGGGCGCTGCAGGACGTCGGCGCGGTGTCGCTCGTCGGCCGACCGCTCGCGACGCTCGTGC
GCCACCTGCTGCCGGGCCGGCGCCTGTTCGTGCTGAGCGCCGACGGCCGCACGCCGGCCACGGTCGCCGCCGAACTCACG
GCGCGCGGCTTCGGCCCGACCCGCATCAGCGTGTTCGAACATCTCGGTGGCCCGCTCGAGCGGCGTCTCGATGGTCTCGC
GCAAGACTGGCCCGTCGCCGAAACCGCCGCGCTCAACCTGATCGCGCTCGACTGCCGGGCCGGCCCCGATGCGCCGCGCC
GCGCGCTCACGCCCGGTCTGCCCGACGACGCGTACCGCCACGACGGCCAGCTCACCAAGCGCGACATGCGCGCATTGACG
CTCGGGCGCCTCGCGCCCGCACCCGGCGAACTGTTGTGGGACGTCGGCGCGGGCAGCGGCTCGATCGGCATCGAATGGAT
GCGCGCGCATCCGTCGTGCCAGACGATCGCGATCGAGTCGCATGCGGAGCGTCAGCGCTTCATCGAGCACAACCGCGACG
CGCTCGGCGTGCCGGGGCTGCAACTCGTCGCGGGGCGCGCGCCCCACGCGCTCGCGGGGCTCGCCGCGCCGGACGCGATC
TTCATCGGCGGCGGCGCGAGCGCACCCGGCGTGCTCGATGCATGCTGGTCGGCGCTGAAGCCCGGCGGCCGGCTCGTCGC
GAACGCGGTCACGCTGCAGGGCGAACTGGCGCTCGCGGCTTGGCGCGACGTGCATGGCGGCACGCTCACGCGCGTGTCGC
TCGCGCATGCCGAGCCGCTCGGCCGTTTCGACACGTGGCGGCAGCCGTTGCCGGTCACGCTGTACGACGGGCGCAAGCCC
GATCCCGCGGCAACGGAATTCACGGGCCCCGCGTGA

Upstream 100 bases:

>100_bases
ACACGGTACCATGCCGACTTTCGCAACGCGGACGGCCGCACCGGCGCCTTCACGGCCGCCGTGCGGCGACTCGATGGAAT
CGGACGATGGGGAAGGGTGC

Downstream 100 bases:

>100_bases
TGCGCGACGAAACCCCCGAACGACCGGCGCCGCTGCGGTTCGGCTATACGACCGGCAGCTGCGCGACCGCGACGTCGCTC
GCCGCCGCGCGACTGCTGCT

Product: precorrin-6y C5,15-methyltransferase subunit CbiE

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MTAWLTVVGIGDDGYAGLGRSARRALLDATRVVGAKRHLDMLPARLRAAREPWPSPFDVSGLLARRDAPVCVLASGDPML
FGVGATLARELSPDEWRVLPAPSSLSLAAARLGWALQDVGAVSLVGRPLATLVRHLLPGRRLFVLSADGRTPATVAAELT
ARGFGPTRISVFEHLGGPLERRLDGLAQDWPVAETAALNLIALDCRAGPDAPRRALTPGLPDDAYRHDGQLTKRDMRALT
LGRLAPAPGELLWDVGAGSGSIGIEWMRAHPSCQTIAIESHAERQRFIEHNRDALGVPGLQLVAGRAPHALAGLAAPDAI
FIGGGASAPGVLDACWSALKPGGRLVANAVTLQGELALAAWRDVHGGTLTRVSLAHAEPLGRFDTWRQPLPVTLYDGRKP
DPAATEFTGPA

Sequences:

>Translated_411_residues
MTAWLTVVGIGDDGYAGLGRSARRALLDATRVVGAKRHLDMLPARLRAAREPWPSPFDVSGLLARRDAPVCVLASGDPML
FGVGATLARELSPDEWRVLPAPSSLSLAAARLGWALQDVGAVSLVGRPLATLVRHLLPGRRLFVLSADGRTPATVAAELT
ARGFGPTRISVFEHLGGPLERRLDGLAQDWPVAETAALNLIALDCRAGPDAPRRALTPGLPDDAYRHDGQLTKRDMRALT
LGRLAPAPGELLWDVGAGSGSIGIEWMRAHPSCQTIAIESHAERQRFIEHNRDALGVPGLQLVAGRAPHALAGLAAPDAI
FIGGGASAPGVLDACWSALKPGGRLVANAVTLQGELALAAWRDVHGGTLTRVSLAHAEPLGRFDTWRQPLPVTLYDGRKP
DPAATEFTGPA
>Mature_410_residues
TAWLTVVGIGDDGYAGLGRSARRALLDATRVVGAKRHLDMLPARLRAAREPWPSPFDVSGLLARRDAPVCVLASGDPMLF
GVGATLARELSPDEWRVLPAPSSLSLAAARLGWALQDVGAVSLVGRPLATLVRHLLPGRRLFVLSADGRTPATVAAELTA
RGFGPTRISVFEHLGGPLERRLDGLAQDWPVAETAALNLIALDCRAGPDAPRRALTPGLPDDAYRHDGQLTKRDMRALTL
GRLAPAPGELLWDVGAGSGSIGIEWMRAHPSCQTIAIESHAERQRFIEHNRDALGVPGLQLVAGRAPHALAGLAAPDAIF
IGGGASAPGVLDACWSALKPGGRLVANAVTLQGELALAAWRDVHGGTLTRVSLAHAEPLGRFDTWRQPLPVTLYDGRKPD
PAATEFTGPA

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 43362; Mature: 43231

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS00047 HISTONE_H4 ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAWLTVVGIGDDGYAGLGRSARRALLDATRVVGAKRHLDMLPARLRAAREPWPSPFDVS
CCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
GLLARRDAPVCVLASGDPMLFGVGATLARELSPDEWRVLPAPSSLSLAAARLGWALQDVG
HHHHCCCCCEEEEECCCCEEEECCHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCC
AVSLVGRPLATLVRHLLPGRRLFVLSADGRTPATVAAELTARGFGPTRISVFEHLGGPLE
HHHHHCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCHHH
RRLDGLAQDWPVAETAALNLIALDCRAGPDAPRRALTPGLPDDAYRHDGQLTKRDMRALT
HHHHHHHCCCCCHHHHEEEEEEEECCCCCCCCHHHCCCCCCCHHHHCCCCHHHHHHHHHH
LGRLAPAPGELLWDVGAGSGSIGIEWMRAHPSCQTIAIESHAERQRFIEHNRDALGVPGL
HHCCCCCCCCEEEEECCCCCCCCEEEEECCCCCEEEEECCHHHHHHHHHCCCCCCCCCCH
QLVAGRAPHALAGLAAPDAIFIGGGASAPGVLDACWSALKPGGRLVANAVTLQGELALAA
HEECCCCCHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCEEEEE
WRDVHGGTLTRVSLAHAEPLGRFDTWRQPLPVTLYDGRKPDPAATEFTGPA
HHHCCCCEEEEEEEHHCCCCCCHHCCCCCCCEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TAWLTVVGIGDDGYAGLGRSARRALLDATRVVGAKRHLDMLPARLRAAREPWPSPFDVS
CEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
GLLARRDAPVCVLASGDPMLFGVGATLARELSPDEWRVLPAPSSLSLAAARLGWALQDVG
HHHHCCCCCEEEEECCCCEEEECCHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCC
AVSLVGRPLATLVRHLLPGRRLFVLSADGRTPATVAAELTARGFGPTRISVFEHLGGPLE
HHHHHCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCHHH
RRLDGLAQDWPVAETAALNLIALDCRAGPDAPRRALTPGLPDDAYRHDGQLTKRDMRALT
HHHHHHHCCCCCHHHHEEEEEEEECCCCCCCCHHHCCCCCCCHHHHCCCCHHHHHHHHHH
LGRLAPAPGELLWDVGAGSGSIGIEWMRAHPSCQTIAIESHAERQRFIEHNRDALGVPGL
HHCCCCCCCCEEEEECCCCCCCCEEEEECCCCCEEEEECCHHHHHHHHHCCCCCCCCCCH
QLVAGRAPHALAGLAAPDAIFIGGGASAPGVLDACWSALKPGGRLVANAVTLQGELALAA
HEECCCCCHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCEEEEE
WRDVHGGTLTRVSLAHAEPLGRFDTWRQPLPVTLYDGRKPDPAATEFTGPA
HHHCCCCEEEEEEEHHCCCCCCHHCCCCCCCEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]