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The map label for this gene is thrS

Identifier: 115351412

GI number: 115351412

Start: 1493119

End: 1495026

Strand: Direct

Name: thrS

Synonym: Bamb_1359

Alternate gene names: 115351412

Gene position: 1493119-1495026 (Clockwise)

Preceding gene: 115351411

Following gene: 115351413

Centisome position: 41.98

GC content: 61.84

Gene sequence:

>1908_bases
ATGGTTTCGATACGCTTGCCTGACGGCTCAGTTCGACAATACGAGCATCCGGTGACAGTTGCCGAGGTTGCAGCCTCGAT
CGGTCCCGGCCTCGCGAAGGCTGCGCTTGGAGGCAAGCTCGACGGCGAGCTCGTCGACACGTCCACGGTCATCGATCGCG
ACGCAGCGCTCGCGATCATCACGGACAAGGATGCCGACGGTCTCGACATCATCCGTCACTCGACCGCGCACTTGCTCGCG
TACGCGGTGAAGGAACTGTATCCGGATGCGCAGGTGACGATCGGTCCCGTGATCGACAACGGCTTCTACTACGACTTCTC
GTATAACCGCCCGTTTACGCCCGAAGATCTGGAAAAGATCGAAAAGCGCATGCAGGAAATCGCGAAGAAGGACGAGCCGG
TGACGCGCCGCGTCGTGTCGCGCGACGAGGCGGCCGGCTATTTCCGCAGCATCGGCGAGAAGTACAAGGCCGAGATCATC
GAATCGATTCCGCAAACCGACGAAATCAAGCTGTACTCGCACGGCGGCTTCACGGATCTGTGCCGCGGCCCGCACGTGCC
GTCGACCGGCAAGCTGAAGGTCTTCAAGCTGATGAAGGTCGCGGGCGCGTACTGGCGCGGCGACTCGAAGAACGAGCAGC
TGCAGCGCATCTACGGTACGGCCTGGACGAAGAAGGAAGACCAGGACCAATACCTGCACATGCTCGAGGAAGCGGAAAAG
CGCGACCACCGCAAGCTCGGCAAGCAGCTCGACCTGTTCCACATGCAGGAAGAGTCTCCGGGCATGGTGTTCTGGCATCC
GAAGGGCTGGGCGCTGTGGCAGCAGGTCGAGCAGTACATGCGCCGCCGCGTGAACGACGCCGGCTACCTCGAGATCAAGA
CGCCGATGATCATGGACCGCTCGCTGTGGGAAGCGTCGGGCCACTGGCAGAACTACCGCGAGAACATGTTCACGACGGAG
TCGGAGAAGCGCGACTACGCGATCAAGCCGATGAACTGTCCGGGGCACGTTCAGGTGTTCAAGCACGGTCTGCGCTCGTA
CCGCGACCTGCCGCTGCGCTACGCGGAATTCGGTTCGTGCCACCGCAACGAGGCATCGGGCGCGCTGCATGGCCTGATGC
GCGTGCGCGGCTTCGTGCAGGACGATGCGCACATCTTCTGTACGGAAGAGCAGTTCATCGCCGAGTCGATCGCGTTCAAT
ACGCTGGCGATGAGCGTGTACAAGGATTTCGGGTTCGAGCACATCGACATCAAGCTGTCGCTGCGCCCCGAACAGCGTGC
GGGCACGGATGAGACGTGGGATCGTGCCGAGCAGGGCCTGCGCGACGCGCTGACGGCGTGCGGCCTGTCGTGGGAAGAGC
TGCCGGGCGAAGGTGCGTTCTATGGTCCGAAGATCGAGTACCACATCAAGGACGCGCTCGGCCGGTCGTGGCAGTGCGGC
ACGCTGCAGCTCGACATGGTGCTGCCGGAGCGCCTCGGTGCCGAGTACGTCGCGGAGGACAACAGCCGCCGCCGGCCGGT
GATGCTGCACCGTGCGATCGTCGGTTCGATGGAGCGATTCCTCGGCATTCTGATCGAGCACCATGCCGGCGCGATGCCGG
CCTGGCTCGCGCCGTTCCAGGCAGTTGTGCTCAATATCGCCGAAAGTCAGGTGGAATATGCACACTCTCTGACCCAAACG
TTGCAAAAACAAGGGGTTAGGGTGGCGGGCGATTTGCGCAACGAGAAGATTAGCTATAAAATACGCGAGCACACGCTGGA
AAAGGTGCCTTATCTCCTCGTCGTGGGTGATAAGGAGCGTGATGCGCAAACGGTAGCCGTGCGTGCCCGTGGCGGCGTCG
ATCTTGGCGTTATGCCGATCGAAGCCTTCGTTGAGCGTCTGCAGGAAGACCTGCGCTCGTTCAAGTAA

Upstream 100 bases:

>100_bases
TCGAAAGCGGGGCCGCATTTTTTTTGTCGCGAAATTTCGCGCGCGACTTTTATATCGCGTACCTGGTTTGCCGCCCACTG
TCGGCATCACGGAGATTGCT

Downstream 100 bases:

>100_bases
CCGCCCTGGCAGCGCGGCTCGTTTTTTTAATTTTTAGAGGAAACGTAACATCGCTACTGATAAGTCGTCGCATCGCATCA
ACGGTGAAATCTCTGCGCCG

Product: threonyl-tRNA synthetase

Products: NA

Alternate protein names: Threonine--tRNA ligase; ThrRS [H]

Number of amino acids: Translated: 635; Mature: 635

Protein sequence:

>635_residues
MVSIRLPDGSVRQYEHPVTVAEVAASIGPGLAKAALGGKLDGELVDTSTVIDRDAALAIITDKDADGLDIIRHSTAHLLA
YAVKELYPDAQVTIGPVIDNGFYYDFSYNRPFTPEDLEKIEKRMQEIAKKDEPVTRRVVSRDEAAGYFRSIGEKYKAEII
ESIPQTDEIKLYSHGGFTDLCRGPHVPSTGKLKVFKLMKVAGAYWRGDSKNEQLQRIYGTAWTKKEDQDQYLHMLEEAEK
RDHRKLGKQLDLFHMQEESPGMVFWHPKGWALWQQVEQYMRRRVNDAGYLEIKTPMIMDRSLWEASGHWQNYRENMFTTE
SEKRDYAIKPMNCPGHVQVFKHGLRSYRDLPLRYAEFGSCHRNEASGALHGLMRVRGFVQDDAHIFCTEEQFIAESIAFN
TLAMSVYKDFGFEHIDIKLSLRPEQRAGTDETWDRAEQGLRDALTACGLSWEELPGEGAFYGPKIEYHIKDALGRSWQCG
TLQLDMVLPERLGAEYVAEDNSRRRPVMLHRAIVGSMERFLGILIEHHAGAMPAWLAPFQAVVLNIAESQVEYAHSLTQT
LQKQGVRVAGDLRNEKISYKIREHTLEKVPYLLVVGDKERDAQTVAVRARGGVDLGVMPIEAFVERLQEDLRSFK

Sequences:

>Translated_635_residues
MVSIRLPDGSVRQYEHPVTVAEVAASIGPGLAKAALGGKLDGELVDTSTVIDRDAALAIITDKDADGLDIIRHSTAHLLA
YAVKELYPDAQVTIGPVIDNGFYYDFSYNRPFTPEDLEKIEKRMQEIAKKDEPVTRRVVSRDEAAGYFRSIGEKYKAEII
ESIPQTDEIKLYSHGGFTDLCRGPHVPSTGKLKVFKLMKVAGAYWRGDSKNEQLQRIYGTAWTKKEDQDQYLHMLEEAEK
RDHRKLGKQLDLFHMQEESPGMVFWHPKGWALWQQVEQYMRRRVNDAGYLEIKTPMIMDRSLWEASGHWQNYRENMFTTE
SEKRDYAIKPMNCPGHVQVFKHGLRSYRDLPLRYAEFGSCHRNEASGALHGLMRVRGFVQDDAHIFCTEEQFIAESIAFN
TLAMSVYKDFGFEHIDIKLSLRPEQRAGTDETWDRAEQGLRDALTACGLSWEELPGEGAFYGPKIEYHIKDALGRSWQCG
TLQLDMVLPERLGAEYVAEDNSRRRPVMLHRAIVGSMERFLGILIEHHAGAMPAWLAPFQAVVLNIAESQVEYAHSLTQT
LQKQGVRVAGDLRNEKISYKIREHTLEKVPYLLVVGDKERDAQTVAVRARGGVDLGVMPIEAFVERLQEDLRSFK
>Mature_635_residues
MVSIRLPDGSVRQYEHPVTVAEVAASIGPGLAKAALGGKLDGELVDTSTVIDRDAALAIITDKDADGLDIIRHSTAHLLA
YAVKELYPDAQVTIGPVIDNGFYYDFSYNRPFTPEDLEKIEKRMQEIAKKDEPVTRRVVSRDEAAGYFRSIGEKYKAEII
ESIPQTDEIKLYSHGGFTDLCRGPHVPSTGKLKVFKLMKVAGAYWRGDSKNEQLQRIYGTAWTKKEDQDQYLHMLEEAEK
RDHRKLGKQLDLFHMQEESPGMVFWHPKGWALWQQVEQYMRRRVNDAGYLEIKTPMIMDRSLWEASGHWQNYRENMFTTE
SEKRDYAIKPMNCPGHVQVFKHGLRSYRDLPLRYAEFGSCHRNEASGALHGLMRVRGFVQDDAHIFCTEEQFIAESIAFN
TLAMSVYKDFGFEHIDIKLSLRPEQRAGTDETWDRAEQGLRDALTACGLSWEELPGEGAFYGPKIEYHIKDALGRSWQCG
TLQLDMVLPERLGAEYVAEDNSRRRPVMLHRAIVGSMERFLGILIEHHAGAMPAWLAPFQAVVLNIAESQVEYAHSLTQT
LQKQGVRVAGDLRNEKISYKIREHTLEKVPYLLVVGDKERDAQTVAVRARGGVDLGVMPIEAFVERLQEDLRSFK

Specific function: Thrs Is Also A Translational Repressor Protein, It Controls The Translation Of Its Own Gene By Binding To Its mRNA. [C]

COG id: COG0441

COG function: function code J; Threonyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI38570111, Length=632, Percent_Identity=39.7151898734177, Blast_Score=474, Evalue=1e-133,
Organism=Homo sapiens, GI38202255, Length=638, Percent_Identity=39.1849529780564, Blast_Score=456, Evalue=1e-128,
Organism=Homo sapiens, GI20070344, Length=651, Percent_Identity=37.3271889400922, Blast_Score=404, Evalue=1e-112,
Organism=Escherichia coli, GI1788013, Length=634, Percent_Identity=59.1482649842271, Blast_Score=792, Evalue=0.0,
Organism=Escherichia coli, GI1786392, Length=137, Percent_Identity=27.7372262773723, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71984184, Length=636, Percent_Identity=38.9937106918239, Blast_Score=473, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI71984192, Length=636, Percent_Identity=38.9937106918239, Blast_Score=473, Evalue=1e-133,
Organism=Saccharomyces cerevisiae, GI6322112, Length=654, Percent_Identity=38.5321100917431, Blast_Score=455, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6322654, Length=398, Percent_Identity=39.9497487437186, Blast_Score=301, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24583842, Length=631, Percent_Identity=39.1442155309033, Blast_Score=473, Evalue=1e-133,
Organism=Drosophila melanogaster, GI28574141, Length=631, Percent_Identity=39.1442155309033, Blast_Score=473, Evalue=1e-133,
Organism=Drosophila melanogaster, GI24583839, Length=631, Percent_Identity=39.1442155309033, Blast_Score=473, Evalue=1e-133,

Paralogues:

None

Copy number: 700 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR012675
- InterPro:   IPR004095
- InterPro:   IPR012676
- InterPro:   IPR002320
- InterPro:   IPR018163
- InterPro:   IPR012947 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF02824 TGS; PF00587 tRNA-synt_2b; PF07973 tRNA_SAD [H]

EC number: =6.1.1.3 [H]

Molecular weight: Translated: 72307; Mature: 72307

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSIRLPDGSVRQYEHPVTVAEVAASIGPGLAKAALGGKLDGELVDTSTVIDRDAALAII
CEEEECCCCCCHHHCCCCHHHHHHHHHCCCHHHHHHCCCCCCCEECCHHHCCCCCEEEEE
TDKDADGLDIIRHSTAHLLAYAVKELYPDAQVTIGPVIDNGFYYDFSYNRPFTPEDLEKI
ECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHH
EKRMQEIAKKDEPVTRRVVSRDEAAGYFRSIGEKYKAEIIESIPQTDEIKLYSHGGFTDL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHH
CRGPHVPSTGKLKVFKLMKVAGAYWRGDSKNEQLQRIYGTAWTKKEDQDQYLHMLEEAEK
HCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
RDHRKLGKQLDLFHMQEESPGMVFWHPKGWALWQQVEQYMRRRVNDAGYLEIKTPMIMDR
HHHHHHCCCCCCEEECCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEECCCHHHCH
SLWEASGHWQNYRENMFTTESEKRDYAIKPMNCPGHVQVFKHGLRSYRDLPLRYAEFGSC
HHHHCCCCHHHHHHHCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCC
HRNEASGALHGLMRVRGFVQDDAHIFCTEEQFIAESIAFNTLAMSVYKDFGFEHIDIKLS
CCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
LRPEQRAGTDETWDRAEQGLRDALTACGLSWEELPGEGAFYGPKIEYHIKDALGRSWQCG
ECCHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEECCEEEEEEHHHCCCCCCCC
TLQLDMVLPERLGAEYVAEDNSRRRPVMLHRAIVGSMERFLGILIEHHAGAMPAWLAPFQ
CEEEEEECHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
AVVLNIAESQVEYAHSLTQTLQKQGVRVAGDLRNEKISYKIREHTLEKVPYLLVVGDKER
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEHHHHHHHHHCCEEEEECCCCC
DAQTVAVRARGGVDLGVMPIEAFVERLQEDLRSFK
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSIRLPDGSVRQYEHPVTVAEVAASIGPGLAKAALGGKLDGELVDTSTVIDRDAALAII
CEEEECCCCCCHHHCCCCHHHHHHHHHCCCHHHHHHCCCCCCCEECCHHHCCCCCEEEEE
TDKDADGLDIIRHSTAHLLAYAVKELYPDAQVTIGPVIDNGFYYDFSYNRPFTPEDLEKI
ECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHH
EKRMQEIAKKDEPVTRRVVSRDEAAGYFRSIGEKYKAEIIESIPQTDEIKLYSHGGFTDL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHH
CRGPHVPSTGKLKVFKLMKVAGAYWRGDSKNEQLQRIYGTAWTKKEDQDQYLHMLEEAEK
HCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
RDHRKLGKQLDLFHMQEESPGMVFWHPKGWALWQQVEQYMRRRVNDAGYLEIKTPMIMDR
HHHHHHCCCCCCEEECCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEECCCHHHCH
SLWEASGHWQNYRENMFTTESEKRDYAIKPMNCPGHVQVFKHGLRSYRDLPLRYAEFGSC
HHHHCCCCHHHHHHHCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCC
HRNEASGALHGLMRVRGFVQDDAHIFCTEEQFIAESIAFNTLAMSVYKDFGFEHIDIKLS
CCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
LRPEQRAGTDETWDRAEQGLRDALTACGLSWEELPGEGAFYGPKIEYHIKDALGRSWQCG
ECCHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEECCEEEEEEHHHCCCCCCCC
TLQLDMVLPERLGAEYVAEDNSRRRPVMLHRAIVGSMERFLGILIEHHAGAMPAWLAPFQ
CEEEEEECHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
AVVLNIAESQVEYAHSLTQTLQKQGVRVAGDLRNEKISYKIREHTLEKVPYLLVVGDKER
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEHHHHHHHHHCCEEEEECCCCC
DAQTVAVRARGGVDLGVMPIEAFVERLQEDLRSFK
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA