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The map label for this gene is iorA [H]

Identifier: 115351284

GI number: 115351284

Start: 1342728

End: 1343189

Strand: Direct

Name: iorA [H]

Synonym: Bamb_1231

Alternate gene names: 115351284

Gene position: 1342728-1343189 (Clockwise)

Preceding gene: 115351283

Following gene: 115351285

Centisome position: 37.75

GC content: 66.45

Gene sequence:

>462_bases
ATGATCACGCTGACCGTCAACGGTGGCGAACGGCATTTCGACGGCAATCCCGACATGCCGTTGCTCTGGTATCTGCGCGA
TGTCCTCGGCCACACGGGCACCAAGTTCGGCTGCGGGATGGCGCTGTGCGGCGCCTGCACCGTGCATCTCGACGGCGTCG
CGATCCGGTCGTGCATCACACCCGTCGCGGCGGCCGCCGGCAAGAAGGTGACGACGATCGAGGGCCTCTCGACGGACGTG
AACCATCCGCTGCAGCAAGCGTGGCAGGAACTGAACGTCGCGCAATGCGGCTACTGTCAGTCCGGGCAGATCATGCAGGC
CGCGTCGCTGCTGAAGACGAATCCCCATCCGAGCGACGCCGACATCGACGACGCGATGTCCGGCAACATCTGCCGCTGCG
GTACCTATACGCGCATCCGCGCGGCGATCCGGCTGGCGGTGCGCCGCGGAGGTGCCGCATGA

Upstream 100 bases:

>100_bases
AACGGCGTCAGGCCCACTTGGTCGTTCGGAATGTGCCCAGCGCCGTTCAAATCCCCACACGACGCCCGCGCGACGCGGCG
TCGCAACCAGGAGGTGAACG

Downstream 100 bases:

>100_bases
ACGCGCCGGAACTCTCCGTCCACAACGAAAGCCGCCGCGCATTGCTGCTCGGCTTCGCATCCGGCGGACTGCTGCTCGCG
TTCGGCGTGCCGTCGCTTGC

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MITLTVNGGERHFDGNPDMPLLWYLRDVLGHTGTKFGCGMALCGACTVHLDGVAIRSCITPVAAAAGKKVTTIEGLSTDV
NHPLQQAWQELNVAQCGYCQSGQIMQAASLLKTNPHPSDADIDDAMSGNICRCGTYTRIRAAIRLAVRRGGAA

Sequences:

>Translated_153_residues
MITLTVNGGERHFDGNPDMPLLWYLRDVLGHTGTKFGCGMALCGACTVHLDGVAIRSCITPVAAAAGKKVTTIEGLSTDV
NHPLQQAWQELNVAQCGYCQSGQIMQAASLLKTNPHPSDADIDDAMSGNICRCGTYTRIRAAIRLAVRRGGAA
>Mature_153_residues
MITLTVNGGERHFDGNPDMPLLWYLRDVLGHTGTKFGCGMALCGACTVHLDGVAIRSCITPVAAAAGKKVTTIEGLSTDV
NHPLQQAWQELNVAQCGYCQSGQIMQAASLLKTNPHPSDADIDDAMSGNICRCGTYTRIRAAIRLAVRRGGAA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=147, Percent_Identity=35.3741496598639, Blast_Score=81, Evalue=3e-16,
Organism=Homo sapiens, GI71773480, Length=97, Percent_Identity=32.9896907216495, Blast_Score=73, Evalue=9e-14,
Organism=Escherichia coli, GI1786480, Length=161, Percent_Identity=40.3726708074534, Blast_Score=105, Evalue=1e-24,
Organism=Escherichia coli, GI1789232, Length=142, Percent_Identity=38.0281690140845, Blast_Score=84, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17540638, Length=140, Percent_Identity=40.7142857142857, Blast_Score=112, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17539860, Length=154, Percent_Identity=35.7142857142857, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32566215, Length=154, Percent_Identity=34.4155844155844, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17737937, Length=152, Percent_Identity=34.8684210526316, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24647193, Length=157, Percent_Identity=34.3949044585987, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24647199, Length=135, Percent_Identity=34.0740740740741, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24647201, Length=152, Percent_Identity=31.5789473684211, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24647195, Length=159, Percent_Identity=32.0754716981132, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24647197, Length=159, Percent_Identity=32.0754716981132, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16214; Mature: 16214

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLTVNGGERHFDGNPDMPLLWYLRDVLGHTGTKFGCGMALCGACTVHLDGVAIRSCIT
CEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEECHHHHHHHHH
PVAAAAGKKVTTIEGLSTDVNHPLQQAWQELNVAQCGYCQSGQIMQAASLLKTNPHPSDA
HHHHHCCCCEEEECCCCCCCCCHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHCCCCCCCC
DIDDAMSGNICRCGTYTRIRAAIRLAVRRGGAA
CCCHHCCCCEEECCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MITLTVNGGERHFDGNPDMPLLWYLRDVLGHTGTKFGCGMALCGACTVHLDGVAIRSCIT
CEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEECHHHHHHHHH
PVAAAAGKKVTTIEGLSTDVNHPLQQAWQELNVAQCGYCQSGQIMQAASLLKTNPHPSDA
HHHHHCCCCEEEECCCCCCCCCHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHCCCCCCCC
DIDDAMSGNICRCGTYTRIRAAIRLAVRRGGAA
CCCHHCCCCEEECCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]