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The map label for this gene is exuR [H]

Identifier: 115351282

GI number: 115351282

Start: 1341596

End: 1342345

Strand: Direct

Name: exuR [H]

Synonym: Bamb_1229

Alternate gene names: 115351282

Gene position: 1341596-1342345 (Clockwise)

Preceding gene: 115351271

Following gene: 115351283

Centisome position: 37.72

GC content: 66.8

Gene sequence:

>750_bases
GTGAACGCGAAGCTCCGGCCAATTCCGTCGACCATTTTTCGGATCATGAAGCAGACAGAACCCAAGCGGCTTTACCAATC
CGTGGCCGCGCAAATCCTCGCATTGATCCGTCAGGGAGGCATTCCCGCCGGTGGGCGACTGCCGCCCGAGCGCGAGCTCG
CGACGACGCTCGGGGTCTCGCGCCCGTCGTTGCGCGAAGCCTTGATCGCCCTCGAAATCGGCGGGCAGATCGAGATACGT
CTCGGCTCCGGGGTCTACGTTCGCGATCCGGGCGAGAGCGACAGCGGCGGCGTGCCGGCGCTGGGCGAGAGCCCGTCGGA
GCTGATGCAGGCGCGCGGGGCCATCGAGGGTTCGGTGATCGTGCTGGCGACTGCGCGATTCTCGGCAGCCACGCTGGACC
GATTGCGTCGCACGGTCGAGCGCATGAAGCGGCTCGCCGTCGCGGGCAAATCGCCCGTCGACGCGGACCGGCAGTTTCAT
ATGCTCATTGCGGAGGTGGCAGGCAACTCCGTGTTGAGCCGCTTCGTGGGCGAGTTGTTCGATAGCCGACACGATCCGAT
TGCCGCCGCGATTCGCGGACATTCGGAAAGCCCGGAAACCTGGGCCGCCGCGGTGCGCGAGCACGAGCAGATCCTGAAGG
CGTTGCAAGCGGGCGATCCGATCGCGGCGCAAACCGCGATGCGCGCCCATCTTCAGGCGTCGGAGGAGCGCTGGATCGGC
GGCGCATTGCAGCACGGGATTGCGCCCTGA

Upstream 100 bases:

>100_bases
CAATTGTGATTATTTTGAAGTGACCATACCAATGGTGTAAACCCTTGTGCCGGGTCTATCCCATGCTGGTCGGGGGTTTC
GCCGCCGTGATAGACTCCGC

Downstream 100 bases:

>100_bases
CGGTGCCGAGGCCGGTCCCGCGAAAGCGCTGACGTCCGGCCTGCGCGAGCATGCGCGCAATGCCGAAACGCGTGCACTCA
TCGCGCGTTCTGCAGGTTCG

Product: GntR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MNAKLRPIPSTIFRIMKQTEPKRLYQSVAAQILALIRQGGIPAGGRLPPERELATTLGVSRPSLREALIALEIGGQIEIR
LGSGVYVRDPGESDSGGVPALGESPSELMQARGAIEGSVIVLATARFSAATLDRLRRTVERMKRLAVAGKSPVDADRQFH
MLIAEVAGNSVLSRFVGELFDSRHDPIAAAIRGHSESPETWAAAVREHEQILKALQAGDPIAAQTAMRAHLQASEERWIG
GALQHGIAP

Sequences:

>Translated_249_residues
MNAKLRPIPSTIFRIMKQTEPKRLYQSVAAQILALIRQGGIPAGGRLPPERELATTLGVSRPSLREALIALEIGGQIEIR
LGSGVYVRDPGESDSGGVPALGESPSELMQARGAIEGSVIVLATARFSAATLDRLRRTVERMKRLAVAGKSPVDADRQFH
MLIAEVAGNSVLSRFVGELFDSRHDPIAAAIRGHSESPETWAAAVREHEQILKALQAGDPIAAQTAMRAHLQASEERWIG
GALQHGIAP
>Mature_249_residues
MNAKLRPIPSTIFRIMKQTEPKRLYQSVAAQILALIRQGGIPAGGRLPPERELATTLGVSRPSLREALIALEIGGQIEIR
LGSGVYVRDPGESDSGGVPALGESPSELMQARGAIEGSVIVLATARFSAATLDRLRRTVERMKRLAVAGKSPVDADRQFH
MLIAEVAGNSVLSRFVGELFDSRHDPIAAAIRGHSESPETWAAAVREHEQILKALQAGDPIAAQTAMRAHLQASEERWIG
GALQHGIAP

Specific function: Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the exuT, uxaCA and uxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082208, Length=228, Percent_Identity=35.0877192982456, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1790780, Length=227, Percent_Identity=34.3612334801762, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790032, Length=223, Percent_Identity=31.8385650224215, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789621, Length=229, Percent_Identity=26.2008733624454, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786303, Length=225, Percent_Identity=30.6666666666667, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1789353, Length=226, Percent_Identity=27.4336283185841, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26708; Mature: 26708

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAKLRPIPSTIFRIMKQTEPKRLYQSVAAQILALIRQGGIPAGGRLPPERELATTLGVS
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCC
RPSLREALIALEIGGQIEIRLGSGVYVRDPGESDSGGVPALGESPSELMQARGAIEGSVI
CHHHHHHHHHEEECCEEEEEECCCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEE
VLATARFSAATLDRLRRTVERMKRLAVAGKSPVDADRQFHMLIAEVAGNSVLSRFVGELF
EEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHH
DSRHDPIAAAIRGHSESPETWAAAVREHEQILKALQAGDPIAAQTAMRAHLQASEERWIG
HCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GALQHGIAP
HHHHCCCCC
>Mature Secondary Structure
MNAKLRPIPSTIFRIMKQTEPKRLYQSVAAQILALIRQGGIPAGGRLPPERELATTLGVS
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCC
RPSLREALIALEIGGQIEIRLGSGVYVRDPGESDSGGVPALGESPSELMQARGAIEGSVI
CHHHHHHHHHEEECCEEEEEECCCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEE
VLATARFSAATLDRLRRTVERMKRLAVAGKSPVDADRQFHMLIAEVAGNSVLSRFVGELF
EEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHH
DSRHDPIAAAIRGHSESPETWAAAVREHEQILKALQAGDPIAAQTAMRAHLQASEERWIG
HCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GALQHGIAP
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA