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The map label for this gene is shiA [H]

Identifier: 115351184

GI number: 115351184

Start: 1241081

End: 1242391

Strand: Direct

Name: shiA [H]

Synonym: Bamb_1131

Alternate gene names: 115351184

Gene position: 1241081-1242391 (Clockwise)

Preceding gene: 115351182

Following gene: 115351185

Centisome position: 34.9

GC content: 68.95

Gene sequence:

>1311_bases
ATGACCCAGTCCCTTCCTTCCGCCCGCCAGCCGGCACGTGCCGCGACGGCCGCGTTCGTCGGCACGATGATCGAGTGGTA
CGACTTCTACATCTACGCGACCGCCGCCGCGCTCGTGTTCGGCGAACTCTATTTCCCGTCGCATGACCGCTTCGTCAGCA
CGATGGCGTCGTTCGCGACGTTCGCGGTCGGCTTCTTCGCGCGCCCGCTCGGTGGCATCGTGTTCGGCCACCTCGGCGAC
CGCATCGGCCGCAAGAAGGCGCTGATGACGACGCTGATGATGATGGGCGTCGCGACCGTGTGCGTCGGGCTGCTGCCCGA
CTATTCGCAGGTCGGCATGCTCGCGCCGGTGCTGCTGATCGTGCTGCGCGTCGTGCAGGGGATCGCCGTCGGCGGCGAGT
GGGGCGGCGCGGTGCTGATGGCGGGCGAGCACGCGCCGCAGGGCCGCCGCACCTTCTTCGCGTCGTTCGCGCAGCTCGGC
AGCCCGGCCGGGCTGATCCTGTCGCTGGTCGCGTTTCGCGCGGTCACGTCGATGGACAAGGCCGATTTCCTCGCATGGGG
CTGGCGCCTGCCGTTTCTCGCGAGCTCGGTGCTGCTCGTCGTCGGCATCCTGATCCGGCTCGGCGTGAACGAGTCGCCGG
AATTCGCGCGCGTGAAGGAAGCGAACCGCACCGTGAAGCTGCCGGTGGCCGAAGTGCTGCGCTCCGCGTCGGGGCTCGTG
CTGCTCTGCATCGGCGCGAACACGATCGGGATCGCGGGCGTCTATTTCACCAACACGTTCATGATCGCGTACACCACGCA
GTACGTCGGCGTGTCGCGTTCGCTGATCCTCGACAGCCTGTTCGCGGTCGCGATCATCCAGTTCATCGCCCAGCCGCTCG
CCGCGTGGATCGCCGAGCGTATCGGCGGCGCGCGTTTCCTGAAGATCGCCGCGCTGCTCGCGATGCTGTCGCCGTACCCG
ATGTTCATGCTCGTGCAGGGTGGCACGTCCGGGTCGCTCGTCGCCGGCATCGCGCTCGCGGTCGTGTGCATGGCCGGCTT
CTACTCGGTGATCGCCGGCTTCGTGAGCGGCGTGTTTCCCGCGCACGTGCGCTATTCGGCGATCTCGCTCGCTTATCAGG
TGTGCGGCGCGATCGCGGGCGGCCTGACGCCGCTCGTCGGCACCTGGCTCGCGCATCGCTTCGCGGGCCAGTGGTGGCCG
CTCGCGGTGTTCTACACGTGTCTCGCCGGCATCTCGCTGCTTTGCATCGTCGCGCTCGACGCGCGACGCGCGGGCCGGCC
GGCCGCGGCCGAAGCGCTCGGCTCGCACTGA

Upstream 100 bases:

>100_bases
CGCCGATAAAGGAGGGGCGCCGCACCGTGCGGCGCGAGGCCGCGACAGACGGCCCGCCACCACGATATAGCGCGTGCCGC
GGCGCGCGTCAGGAGCCCGC

Downstream 100 bases:

>100_bases
CCCTCGACGAACGAATTCATCGGAGTGCAAATGAAAGACCTGTTGGAAATCGACGGTGCCCGCCTGTGGCGGAGCCTGGC
CGACATGGCGCGCATCGGCG

Product: major facilitator transporter

Products: Proton [Cytoplasm]; shikimate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MTQSLPSARQPARAATAAFVGTMIEWYDFYIYATAAALVFGELYFPSHDRFVSTMASFATFAVGFFARPLGGIVFGHLGD
RIGRKKALMTTLMMMGVATVCVGLLPDYSQVGMLAPVLLIVLRVVQGIAVGGEWGGAVLMAGEHAPQGRRTFFASFAQLG
SPAGLILSLVAFRAVTSMDKADFLAWGWRLPFLASSVLLVVGILIRLGVNESPEFARVKEANRTVKLPVAEVLRSASGLV
LLCIGANTIGIAGVYFTNTFMIAYTTQYVGVSRSLILDSLFAVAIIQFIAQPLAAWIAERIGGARFLKIAALLAMLSPYP
MFMLVQGGTSGSLVAGIALAVVCMAGFYSVIAGFVSGVFPAHVRYSAISLAYQVCGAIAGGLTPLVGTWLAHRFAGQWWP
LAVFYTCLAGISLLCIVALDARRAGRPAAAEALGSH

Sequences:

>Translated_436_residues
MTQSLPSARQPARAATAAFVGTMIEWYDFYIYATAAALVFGELYFPSHDRFVSTMASFATFAVGFFARPLGGIVFGHLGD
RIGRKKALMTTLMMMGVATVCVGLLPDYSQVGMLAPVLLIVLRVVQGIAVGGEWGGAVLMAGEHAPQGRRTFFASFAQLG
SPAGLILSLVAFRAVTSMDKADFLAWGWRLPFLASSVLLVVGILIRLGVNESPEFARVKEANRTVKLPVAEVLRSASGLV
LLCIGANTIGIAGVYFTNTFMIAYTTQYVGVSRSLILDSLFAVAIIQFIAQPLAAWIAERIGGARFLKIAALLAMLSPYP
MFMLVQGGTSGSLVAGIALAVVCMAGFYSVIAGFVSGVFPAHVRYSAISLAYQVCGAIAGGLTPLVGTWLAHRFAGQWWP
LAVFYTCLAGISLLCIVALDARRAGRPAAAEALGSH
>Mature_435_residues
TQSLPSARQPARAATAAFVGTMIEWYDFYIYATAAALVFGELYFPSHDRFVSTMASFATFAVGFFARPLGGIVFGHLGDR
IGRKKALMTTLMMMGVATVCVGLLPDYSQVGMLAPVLLIVLRVVQGIAVGGEWGGAVLMAGEHAPQGRRTFFASFAQLGS
PAGLILSLVAFRAVTSMDKADFLAWGWRLPFLASSVLLVVGILIRLGVNESPEFARVKEANRTVKLPVAEVLRSASGLVL
LCIGANTIGIAGVYFTNTFMIAYTTQYVGVSRSLILDSLFAVAIIQFIAQPLAAWIAERIGGARFLKIAALLAMLSPYPM
FMLVQGGTSGSLVAGIALAVVCMAGFYSVIAGFVSGVFPAHVRYSAISLAYQVCGAIAGGLTPLVGTWLAHRFAGQWWPL
AVFYTCLAGISLLCIVALDARRAGRPAAAEALGSH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788292, Length=431, Percent_Identity=39.4431554524362, Blast_Score=286, Evalue=1e-78,
Organism=Escherichia coli, GI1790550, Length=425, Percent_Identity=32, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1789941, Length=418, Percent_Identity=34.2105263157895, Blast_Score=204, Evalue=8e-54,
Organism=Escherichia coli, GI1788942, Length=380, Percent_Identity=29.7368421052632, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI87082231, Length=237, Percent_Identity=23.2067510548523, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082404, Length=395, Percent_Identity=22.0253164556962, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004736
- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 46156; Mature: 46025

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSLPSARQPARAATAAFVGTMIEWYDFYIYATAAALVFGELYFPSHDRFVSTMASFAT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
FAVGFFARPLGGIVFGHLGDRIGRKKALMTTLMMMGVATVCVGLLPDYSQVGMLAPVLLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VLRVVQGIAVGGEWGGAVLMAGEHAPQGRRTFFASFAQLGSPAGLILSLVAFRAVTSMDK
HHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCH
ADFLAWGWRLPFLASSVLLVVGILIRLGVNESPEFARVKEANRTVKLPVAEVLRSASGLV
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEECCHHHHHCCCCCEE
LLCIGANTIGIAGVYFTNTFMIAYTTQYVGVSRSLILDSLFAVAIIQFIAQPLAAWIAER
EEEECCCCHHHHHHHHHHEEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGGARFLKIAALLAMLSPYPMFMLVQGGTSGSLVAGIALAVVCMAGFYSVIAGFVSGVFP
HCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHVRYSAISLAYQVCGAIAGGLTPLVGTWLAHRFAGQWWPLAVFYTCLAGISLLCIVALD
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ARRAGRPAAAEALGSH
HHCCCCCHHHHHCCCC
>Mature Secondary Structure 
TQSLPSARQPARAATAAFVGTMIEWYDFYIYATAAALVFGELYFPSHDRFVSTMASFAT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
FAVGFFARPLGGIVFGHLGDRIGRKKALMTTLMMMGVATVCVGLLPDYSQVGMLAPVLLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VLRVVQGIAVGGEWGGAVLMAGEHAPQGRRTFFASFAQLGSPAGLILSLVAFRAVTSMDK
HHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCH
ADFLAWGWRLPFLASSVLLVVGILIRLGVNESPEFARVKEANRTVKLPVAEVLRSASGLV
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEECCHHHHHCCCCCEE
LLCIGANTIGIAGVYFTNTFMIAYTTQYVGVSRSLILDSLFAVAIIQFIAQPLAAWIAER
EEEECCCCHHHHHHHHHHEEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGGARFLKIAALLAMLSPYPMFMLVQGGTSGSLVAGIALAVVCMAGFYSVIAGFVSGVFP
HCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHVRYSAISLAYQVCGAIAGGLTPLVGTWLAHRFAGQWWPLAVFYTCLAGISLLCIVALD
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ARRAGRPAAAEALGSH
HHCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; shikimate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + shikimate [Periplasm] = Proton [Cytoplasm] + shikimate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9524262; 9097040; 9278503 [H]