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The map label for this gene is uvrC

Identifier: 115351073

GI number: 115351073

Start: 1107945

End: 1109999

Strand: Direct

Name: uvrC

Synonym: Bamb_1019

Alternate gene names: 115351073

Gene position: 1107945-1109999 (Clockwise)

Preceding gene: 115351069

Following gene: 115351074

Centisome position: 31.15

GC content: 68.08

Gene sequence:

>2055_bases
ATGACATCCCCAGAAGCCGTCGACATCCCGTTCGAACCGAAGAAGATCCTCGCCCAGTTGCCGCACATGCCGGGCGTCTA
CCGCTACTACGACACGGCGGGCGCCGTGCTTTACGTCGGCAAGGCGCGCGACCTGAAGAAGCGCGTGTCGAGCTATTTCA
CGAAGACGCAGCTGTCGCCGCGCATCGCGATGATGGTCACGCGCATCGCGCGCATCGAGACGACCGTCACGCGCTCCGAG
GCCGAGGCGCTGCTGCTCGAGAACAACCTGATCAAGGCGCTCGCGCCGCGCTACAACATCCTGTTTCGCGACGACAAGTC
GTATCCGTACCTGAAGCTCACCGCGCACCGCTTTCCGCGCATGGCCTACTACCGCGGCTCGGTCGACAAGCAGAACCAGT
ATTTCGGACCGTTCCCCAGCGCGTGGGCCGTGCGCGAGAGCATCCAGATCCTGCAGCGCGTCTTCCAGTTGCGCACCTGC
GAGGATTCCGTCTTCAACAACCGCACGCGGCCGTGCCTGCTGCATCAGATCGGGCGCTGCACGGCGCCGTGCGTCGGCGC
GATTTCCGCGGACGACTACGCGATCGACGTGTCGAACGCCGCGCGTTTCCTGCTCGGCCGGCAGTCGGAAGTGATGAAGG
AGCTCGAGCAGAAGATGCACGCGTTCGCGGCCGAGCTGAAGTTCGAGCAGGCGGCGGCCGTGCGCAACCAGATGAGTTCG
CTCGCGACGGTGCTGCACCAGCAGGCGATCGAGGTCGGCAGCGACAGCGACGTCGACATCCTCGCGGTGGTCGCGCAGGG
CGGACGCGTGTGCGTGAACCTGGCGATGGTGCGCGGCGGCCGGCATCTTGGCGACAAGGCCTATTTCCCCGCGCATGTCG
AAAGTGCGCTGACGCTTGCCGAAGGTGGCCTCGGCGACGAAGCCGACGGTGCGGATGGTGCCGACGAAGCCGCCGCGGCG
TTGCCCGGCGAGCCCGCGGACGAAGCTGCCGCCGCGCGTGACGCGGCGTCGTCGGCGTCGGGGGCATCGTCGGCATCGGT
CGAGGCCGAGGTGCTCGATGCGTTCATCGCGCAGCACTATCTCGGCAATCGCGTGCCGCCCGTGCTTGTCGTGAGCCATG
CGCCCGCCAGCCGCGACCTGCTCGAGCTGCTGTCCGAGCAGGCCGGTCACAAGGTTTCGCTGGTGCGGCAGCCGCAGGGG
CAGCGGCGCGCATGGCTGTCGATGGCTGAACAGAATGCCCGGCTCGCGCTTGCGCGGCTGCTGTCCGAGCAGGGCTCGCA
GCAGGCGCGCACGCGCGCGCTCGCGGAGACGCTCAGCTTCGAATGCGACGATCTCGCGATGCTGCGGATCGAGTGTTTCG
ACATCAGTCACACGATGGGCGAGGCGACGCAGGCGTCGTGCGTCGTCTACCACCATCACAAGATGCAGTCGGGCGAGTAC
CGTCGCTACAACATCACCGGCATCACGCCGGGCGACGATTACGCGGCCATGCGGCAGGTGCTGACGCGCCGCTACGAGAA
GATGGTCGAGCAGGCCGCGCAGGCTGCCGCCGCCGACGCGGCAGCCGGCATCGACGGCGAATCGACGCGCGAGGCCGAGG
CGTCGAGTTTGCTGCCGAACATCGTGCTGATCGACGGCGGCAAGGGACAGGTCGAGATCGCGCGGCAGGTGTTCACCGAG
CTCGGGCTCGACACGTCGATGCTGGTTGGCGTCGCGAAGGGCGAGGGGCGCAAGGTCGGCCTCGAGACGCTCGTGTTCGC
GGACGGCCGCACGCCGCTCGAACTCGGCAAGGAGAGCGCCGCGCTGATGCTCGTCGCGCAGATCCGCGACGAGGCGCACC
GCTTTGCGATCACCGGGATGCGCGCGAAGCGGGCGAAGGCACGCCAGACGTCGCGGCTCGAGGAGCTCGAAGGGATCGGC
GCGAAACGCCGTCAGCGGCTGCTCGCGCGGTTCGGCGGGCTGCGCGGGGTGGTCGCCGCGAGCGTCGAGGAACTGGCGAG
CGTCGAGGGCATCTCGCACGCGCTCGCCGAGCAGATCTACAAGCAGCTTCACTGA

Upstream 100 bases:

>100_bases
CGGGGGCGGGGGCGGTGCGGGGCATCGATGCGGGCGGTGAATGCTCTAAACTGGCGATTCTAATGGACCCGTTCCGCGCC
ACAAGGCCCCCGGATCACGC

Downstream 100 bases:

>100_bases
TCCGGGCCGTGCGACCGGCCGTGCCTGCCCGCGCTCTCGCGTTCTTGCGTCCTTGTAGCAGGCCGGTCGACACGGCACAA
TTGCGAATCCCTTACTGACC

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 684; Mature: 683

Protein sequence:

>684_residues
MTSPEAVDIPFEPKKILAQLPHMPGVYRYYDTAGAVLYVGKARDLKKRVSSYFTKTQLSPRIAMMVTRIARIETTVTRSE
AEALLLENNLIKALAPRYNILFRDDKSYPYLKLTAHRFPRMAYYRGSVDKQNQYFGPFPSAWAVRESIQILQRVFQLRTC
EDSVFNNRTRPCLLHQIGRCTAPCVGAISADDYAIDVSNAARFLLGRQSEVMKELEQKMHAFAAELKFEQAAAVRNQMSS
LATVLHQQAIEVGSDSDVDILAVVAQGGRVCVNLAMVRGGRHLGDKAYFPAHVESALTLAEGGLGDEADGADGADEAAAA
LPGEPADEAAAARDAASSASGASSASVEAEVLDAFIAQHYLGNRVPPVLVVSHAPASRDLLELLSEQAGHKVSLVRQPQG
QRRAWLSMAEQNARLALARLLSEQGSQQARTRALAETLSFECDDLAMLRIECFDISHTMGEATQASCVVYHHHKMQSGEY
RRYNITGITPGDDYAAMRQVLTRRYEKMVEQAAQAAAADAAAGIDGESTREAEASSLLPNIVLIDGGKGQVEIARQVFTE
LGLDTSMLVGVAKGEGRKVGLETLVFADGRTPLELGKESAALMLVAQIRDEAHRFAITGMRAKRAKARQTSRLEELEGIG
AKRRQRLLARFGGLRGVVAASVEELASVEGISHALAEQIYKQLH

Sequences:

>Translated_684_residues
MTSPEAVDIPFEPKKILAQLPHMPGVYRYYDTAGAVLYVGKARDLKKRVSSYFTKTQLSPRIAMMVTRIARIETTVTRSE
AEALLLENNLIKALAPRYNILFRDDKSYPYLKLTAHRFPRMAYYRGSVDKQNQYFGPFPSAWAVRESIQILQRVFQLRTC
EDSVFNNRTRPCLLHQIGRCTAPCVGAISADDYAIDVSNAARFLLGRQSEVMKELEQKMHAFAAELKFEQAAAVRNQMSS
LATVLHQQAIEVGSDSDVDILAVVAQGGRVCVNLAMVRGGRHLGDKAYFPAHVESALTLAEGGLGDEADGADGADEAAAA
LPGEPADEAAAARDAASSASGASSASVEAEVLDAFIAQHYLGNRVPPVLVVSHAPASRDLLELLSEQAGHKVSLVRQPQG
QRRAWLSMAEQNARLALARLLSEQGSQQARTRALAETLSFECDDLAMLRIECFDISHTMGEATQASCVVYHHHKMQSGEY
RRYNITGITPGDDYAAMRQVLTRRYEKMVEQAAQAAAADAAAGIDGESTREAEASSLLPNIVLIDGGKGQVEIARQVFTE
LGLDTSMLVGVAKGEGRKVGLETLVFADGRTPLELGKESAALMLVAQIRDEAHRFAITGMRAKRAKARQTSRLEELEGIG
AKRRQRLLARFGGLRGVVAASVEELASVEGISHALAEQIYKQLH
>Mature_683_residues
TSPEAVDIPFEPKKILAQLPHMPGVYRYYDTAGAVLYVGKARDLKKRVSSYFTKTQLSPRIAMMVTRIARIETTVTRSEA
EALLLENNLIKALAPRYNILFRDDKSYPYLKLTAHRFPRMAYYRGSVDKQNQYFGPFPSAWAVRESIQILQRVFQLRTCE
DSVFNNRTRPCLLHQIGRCTAPCVGAISADDYAIDVSNAARFLLGRQSEVMKELEQKMHAFAAELKFEQAAAVRNQMSSL
ATVLHQQAIEVGSDSDVDILAVVAQGGRVCVNLAMVRGGRHLGDKAYFPAHVESALTLAEGGLGDEADGADGADEAAAAL
PGEPADEAAAARDAASSASGASSASVEAEVLDAFIAQHYLGNRVPPVLVVSHAPASRDLLELLSEQAGHKVSLVRQPQGQ
RRAWLSMAEQNARLALARLLSEQGSQQARTRALAETLSFECDDLAMLRIECFDISHTMGEATQASCVVYHHHKMQSGEYR
RYNITGITPGDDYAAMRQVLTRRYEKMVEQAAQAAAADAAAGIDGESTREAEASSLLPNIVLIDGGKGQVEIARQVFTEL
GLDTSMLVGVAKGEGRKVGLETLVFADGRTPLELGKESAALMLVAQIRDEAHRFAITGMRAKRAKARQTSRLEELEGIGA
KRRQRLLARFGGLRGVVAASVEELASVEGISHALAEQIYKQLH

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=683, Percent_Identity=41.5812591508053, Blast_Score=510, Evalue=1e-145,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 74549; Mature: 74418

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPEAVDIPFEPKKILAQLPHMPGVYRYYDTAGAVLYVGKARDLKKRVSSYFTKTQLSP
CCCCCCCCCCCCHHHHHHHCCCCCCHHHEECCCCEEEEECCHHHHHHHHHHHHHHHCCCH
RIAMMVTRIARIETTVTRSEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTAHRFPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEHHHCCC
MAYYRGSVDKQNQYFGPFPSAWAVRESIQILQRVFQLRTCEDSVFNNRTRPCLLHQIGRC
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
TAPCVGAISADDYAIDVSNAARFLLGRQSEVMKELEQKMHAFAAELKFEQAAAVRNQMSS
CCCCCCCCCCCCEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATVLHQQAIEVGSDSDVDILAVVAQGGRVCVNLAMVRGGRHLGDKAYFPAHVESALTLA
HHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEHHHHCCCCCCCCCCCCHHHHHHHHHH
EGGLGDEADGADGADEAAAALPGEPADEAAAARDAASSASGASSASVEAEVLDAFIAQHY
CCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
LGNRVPPVLVVSHAPASRDLLELLSEQAGHKVSLVRQPQGQRRAWLSMAEQNARLALARL
HCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
LSEQGSQQARTRALAETLSFECDDLAMLRIECFDISHTMGEATQASCVVYHHHKMQSGEY
HHHCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEECHHHHCCCCCCEEEEEEECCCCCCCC
RRYNITGITPGDDYAAMRQVLTRRYEKMVEQAAQAAAADAAAGIDGESTREAEASSLLPN
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCE
IVLIDGGKGQVEIARQVFTELGLDTSMLVGVAKGEGRKVGLETLVFADGRTPLELGKESA
EEEEECCCCHHHHHHHHHHHHCCCHHHEEEEECCCCCEECCEEEEEECCCCHHHHCCCHH
ALMLVAQIRDEAHRFAITGMRAKRAKARQTSRLEELEGIGAKRRQRLLARFGGLRGVVAA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHH
SVEELASVEGISHALAEQIYKQLH
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSPEAVDIPFEPKKILAQLPHMPGVYRYYDTAGAVLYVGKARDLKKRVSSYFTKTQLSP
CCCCCCCCCCCHHHHHHHCCCCCCHHHEECCCCEEEEECCHHHHHHHHHHHHHHHCCCH
RIAMMVTRIARIETTVTRSEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTAHRFPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEHHHCCC
MAYYRGSVDKQNQYFGPFPSAWAVRESIQILQRVFQLRTCEDSVFNNRTRPCLLHQIGRC
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
TAPCVGAISADDYAIDVSNAARFLLGRQSEVMKELEQKMHAFAAELKFEQAAAVRNQMSS
CCCCCCCCCCCCEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATVLHQQAIEVGSDSDVDILAVVAQGGRVCVNLAMVRGGRHLGDKAYFPAHVESALTLA
HHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEHHHHCCCCCCCCCCCCHHHHHHHHHH
EGGLGDEADGADGADEAAAALPGEPADEAAAARDAASSASGASSASVEAEVLDAFIAQHY
CCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
LGNRVPPVLVVSHAPASRDLLELLSEQAGHKVSLVRQPQGQRRAWLSMAEQNARLALARL
HCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
LSEQGSQQARTRALAETLSFECDDLAMLRIECFDISHTMGEATQASCVVYHHHKMQSGEY
HHHCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEECHHHHCCCCCCEEEEEEECCCCCCCC
RRYNITGITPGDDYAAMRQVLTRRYEKMVEQAAQAAAADAAAGIDGESTREAEASSLLPN
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCE
IVLIDGGKGQVEIARQVFTELGLDTSMLVGVAKGEGRKVGLETLVFADGRTPLELGKESA
EEEEECCCCHHHHHHHHHHHHCCCHHHEEEEECCCCCEECCEEEEEECCCCHHHHCCCHH
ALMLVAQIRDEAHRFAITGMRAKRAKARQTSRLEELEGIGAKRRQRLLARFGGLRGVVAA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHH
SVEELASVEGISHALAEQIYKQLH
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA