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The map label for this gene is rnc [H]

Identifier: 115351064

GI number: 115351064

Start: 1098776

End: 1100053

Strand: Direct

Name: rnc [H]

Synonym: Bamb_1010

Alternate gene names: 115351064

Gene position: 1098776-1100053 (Clockwise)

Preceding gene: 115351063

Following gene: 115351065

Centisome position: 30.89

GC content: 69.25

Gene sequence:

>1278_bases
ATGCCCCCATCCCAGTTGGAAAGCCGGCTGCGCTACGAATTTCGCAATGCGGAATTGTTGCGCCAGGCTTTGACCCACCG
CAGTCACAGTGCCACGCATAACGAACGGCTCGAGTTTCTCGGCGATTCCGTTCTGAATTGCGCGGTGGCCGCCCTTTTGT
TCCAGCGTTTCAGCAAGCTGGACGAAGGCGACCTGTCGCGCGTGCGCGCCAATCTCGTCAAGCAGCAGTCGCTGTATGAA
ATCGCTCAGGCCCTGAATATCTCCGAAGGGTTGCGGCTGGGCGAGGGCGAGCTGCGCAGCGGCGGCTTCCGCCGCCCGTC
GATCCTCGCGGACGCGTTCGAAGCCATCATCGGGGCCGTATTCCTCGATGGCGGCTTCGAAGCCGCCCAAGGGGTCATCA
AGCGCCTCTATATCCCGATTCTCGACCACATCGATCCGCGCACGCTCGGCAAGGACGCGAAGACGCTGCTGCAGGAGTAC
CTGCAGGGGCACAAGATCGCGCTGCCGACCTACACGGTCGTCGCGACGCATGGTGCGGCGCACAATCAGCAGTTCGAGGT
CGAATGCACGGTGCCGAAGCTCGACGTGAAGGTGTCGGGCTCCGGCGCGAGCCGGCGGGCAGCCGAGCAGGCTGCCGCGA
AGAAGGCGCTCGACGAGGTGCTGGCGGCCGCGCCGATGCTGGCCGCGAAGCCGAAGCGTTCGAAGAACGCACGCGGATCG
AAGCACGTCGAGCCCGAAATCGTGCCGGGCGTGAAGGGTGTGCAGGAAGCGCTCGACCTGCGTTCTCCGGAACGCAAGGA
GCGTGCGGCGGCGCGCGATGCGAAGGTGGCCGCGGCTGCGGTTGCAGCGACCGACGCCGACACGCCGCCGAGCGAGCGAC
CGACGCCGACGCCGATGGCCGCGATTCGCGCGGCGCATGTGGAAACGGCCGCGGACAAGGCTGACCGTGCCGCGAAGCCG
ACGGCCGACAAACCTGCCGAAAAGGCGTCCGACAAGCCGTCGGATCGCGGCGAAACCGGCCCGCGCGCGGCGGACAAGCC
GGCCGAGCGTGCCGACAAGCCCGCGGAAAGTGCAGGCGCACCGCGTGCAGCCGACAAGCCGGCGGGCCAGGCGGCCGATC
CGGCCGTGTCGTCCACGGACAAGCCGGCTGCCGGTTCCGATGCCGCCACGCGCGCGACGCTGCGCGCCCGCGACGCCGCG
GCGCCCGATGCCGACACGCCGCCGGGCGGCGCGACCCTCGCCGCCGCGCAGGCGCGCGCGGCCGATGCCGACCACTGA

Upstream 100 bases:

>100_bases
GGACTACTTTAAGAACCGGCGGTAACACCGCTCCGTCACGCCTTTTCGCGTCCGGCCGTGCCGTTTCGGCCCGACCGGCG
CCCGCGTTATACTCCTGCAC

Downstream 100 bases:

>100_bases
ATTGCCCACCGATCGTGCCGCGCGCCGCGCGGCCGGTTCAGAACCTGTCTCCCAAACGATATGAACACTCCCGCTCCTAC
CGGTTTCCGTTGCGGCATGA

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III [H]

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MPPSQLESRLRYEFRNAELLRQALTHRSHSATHNERLEFLGDSVLNCAVAALLFQRFSKLDEGDLSRVRANLVKQQSLYE
IAQALNISEGLRLGEGELRSGGFRRPSILADAFEAIIGAVFLDGGFEAAQGVIKRLYIPILDHIDPRTLGKDAKTLLQEY
LQGHKIALPTYTVVATHGAAHNQQFEVECTVPKLDVKVSGSGASRRAAEQAAAKKALDEVLAAAPMLAAKPKRSKNARGS
KHVEPEIVPGVKGVQEALDLRSPERKERAAARDAKVAAAAVAATDADTPPSERPTPTPMAAIRAAHVETAADKADRAAKP
TADKPAEKASDKPSDRGETGPRAADKPAERADKPAESAGAPRAADKPAGQAADPAVSSTDKPAAGSDAATRATLRARDAA
APDADTPPGGATLAAAQARAADADH

Sequences:

>Translated_425_residues
MPPSQLESRLRYEFRNAELLRQALTHRSHSATHNERLEFLGDSVLNCAVAALLFQRFSKLDEGDLSRVRANLVKQQSLYE
IAQALNISEGLRLGEGELRSGGFRRPSILADAFEAIIGAVFLDGGFEAAQGVIKRLYIPILDHIDPRTLGKDAKTLLQEY
LQGHKIALPTYTVVATHGAAHNQQFEVECTVPKLDVKVSGSGASRRAAEQAAAKKALDEVLAAAPMLAAKPKRSKNARGS
KHVEPEIVPGVKGVQEALDLRSPERKERAAARDAKVAAAAVAATDADTPPSERPTPTPMAAIRAAHVETAADKADRAAKP
TADKPAEKASDKPSDRGETGPRAADKPAERADKPAESAGAPRAADKPAGQAADPAVSSTDKPAAGSDAATRATLRARDAA
APDADTPPGGATLAAAQARAADADH
>Mature_424_residues
PPSQLESRLRYEFRNAELLRQALTHRSHSATHNERLEFLGDSVLNCAVAALLFQRFSKLDEGDLSRVRANLVKQQSLYEI
AQALNISEGLRLGEGELRSGGFRRPSILADAFEAIIGAVFLDGGFEAAQGVIKRLYIPILDHIDPRTLGKDAKTLLQEYL
QGHKIALPTYTVVATHGAAHNQQFEVECTVPKLDVKVSGSGASRRAAEQAAAKKALDEVLAAAPMLAAKPKRSKNARGSK
HVEPEIVPGVKGVQEALDLRSPERKERAAARDAKVAAAAVAATDADTPPSERPTPTPMAAIRAAHVETAADKADRAAKPT
ADKPAEKASDKPSDRGETGPRAADKPAERADKPAESAGAPRAADKPAGQAADPAVSSTDKPAAGSDAATRATLRARDAAA
PDADTPPGGATLAAAQARAADADH

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Homo sapiens, GI155030236, Length=226, Percent_Identity=26.9911504424779, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI155030234, Length=226, Percent_Identity=26.9911504424779, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1788920, Length=203, Percent_Identity=53.2019704433498, Blast_Score=215, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI193202651, Length=197, Percent_Identity=30.9644670050761, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17506883, Length=197, Percent_Identity=30.9644670050761, Blast_Score=94, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323895, Length=97, Percent_Identity=35.0515463917526, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17137682, Length=235, Percent_Identity=27.6595744680851, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 44725; Mature: 44594

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS50137 DS_RBD ; PS00517 RNASE_3_1 ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPSQLESRLRYEFRNAELLRQALTHRSHSATHNERLEFLGDSVLNCAVAALLFQRFSKL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DEGDLSRVRANLVKQQSLYEIAQALNISEGLRLGEGELRSGGFRRPSILADAFEAIIGAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
FLDGGFEAAQGVIKRLYIPILDHIDPRTLGKDAKTLLQEYLQGHKIALPTYTVVATHGAA
HHCCCHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHCCCEEECCEEEEEEECCCC
HNQQFEVECTVPKLDVKVSGSGASRRAAEQAAAKKALDEVLAAAPMLAAKPKRSKNARGS
CCCEEEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
KHVEPEIVPGVKGVQEALDLRSPERKERAAARDAKVAAAAVAATDADTPPSERPTPTPMA
CCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
AIRAAHVETAADKADRAAKPTADKPAEKASDKPSDRGETGPRAADKPAERADKPAESAGA
HHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHCCCCHHHCCC
PRAADKPAGQAADPAVSSTDKPAAGSDAATRATLRARDAAAPDADTPPGGATLAAAQARA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
ADADH
CCCCC
>Mature Secondary Structure 
PPSQLESRLRYEFRNAELLRQALTHRSHSATHNERLEFLGDSVLNCAVAALLFQRFSKL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DEGDLSRVRANLVKQQSLYEIAQALNISEGLRLGEGELRSGGFRRPSILADAFEAIIGAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
FLDGGFEAAQGVIKRLYIPILDHIDPRTLGKDAKTLLQEYLQGHKIALPTYTVVATHGAA
HHCCCHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHCCCEEECCEEEEEEECCCC
HNQQFEVECTVPKLDVKVSGSGASRRAAEQAAAKKALDEVLAAAPMLAAKPKRSKNARGS
CCCEEEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
KHVEPEIVPGVKGVQEALDLRSPERKERAAARDAKVAAAAVAATDADTPPSERPTPTPMA
CCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
AIRAAHVETAADKADRAAKPTADKPAEKASDKPSDRGETGPRAADKPAERADKPAESAGA
HHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHCCCCHHHCCC
PRAADKPAGQAADPAVSSTDKPAAGSDAATRATLRARDAAAPDADTPPGGATLAAAQARA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
ADADH
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]