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The map label for this gene is degP [H]

Identifier: 115351060

GI number: 115351060

Start: 1093955

End: 1095454

Strand: Direct

Name: degP [H]

Synonym: Bamb_1006

Alternate gene names: 115351060

Gene position: 1093955-1095454 (Clockwise)

Preceding gene: 115351059

Following gene: 115351061

Centisome position: 30.76

GC content: 68.13

Gene sequence:

>1500_bases
ATGACGAAACTCACGCTGCGCAACGTGTTCGCGGCGGCGGTGCTGTGTGCCTGCCTGCCCCTCATCCCGCATACCGCGGT
GGCGGCCACGCCGCCCGCCGCCAGCCTTCCCGACTTCGCCGATCTGGTCGAAAAGGTCGGGCCGGCCGTCGTGAACATCC
GGACTACCGCGAACGTGCCGATTCCCGGCCCGCGCGGTGCGCTCCCGCCGGGCTTCGACAACGGCGACATGTCGGAATTC
TTCCGGCGCTTCTTCGGCATTCCGCTGCCGCAGGCGCCCGGCAACGGTGGCGGCAACGGCAATCCGAAGAACGCGCCGGC
GCCGGACAATCCGCCCGACGCCGAGCAGAACCGCGGCGTCGGTTCGGGCTTCATCGTGTCGGCGGACGGTTACGTGATGA
CGAACGCGCACGTCGTCGACGATGCGGACACCATCTACGTGACGCTGACCGACAAGCGCGAATTCAAGGCGAAGCTGATC
GGCGTCGACGACCGCACGGACGTCGCGGTGGTCAAGATCCAGGCGTCGAACCTGCCGGTCGTCGCGATCGGCGATTCGAA
CAAGGTGCGCGTCGGCGAGTGGGTCGTCGCGATCGGTTCGCCGTTCGGCCTCGACAACACCGTGACGGCCGGCATCGTGA
GCTCGAAGAGCCGCAACACGGGCGACTACCTGCCGTTCATCCAGACCGACGTCGCGGTGAACCCCGGCAACTCGGGCGGC
CCGCTGATCAACATGCAGGGCGAGGTGATCGGCATCAACTCGCAGATCTACAGCCGCACCGGCGGTTTCATGGGCATTTC
GTTCGCGATCCCGATCGACGAGGCGATGCGCGTGGCCGACCAGCTGAAGGCGACCGGCAAGGTCACGCGCGGCCGCATCG
CGGTGGCGATCGGCGAGGTGACGAAGGACGTGGCCGATTCGATCGGGCTGCCGAAGGCGGAGGGCGCGCTCGTCAGCAGC
GTCGAGCCGGGCGGTCCGGCCGACAAGGCGGGCATCCAGCCGGGCGACATCATCCTGAAGTTCAACGGCCGGCCGGTCGA
GACGGCGTCGGATCTGCCGCGCATGGTCGGCGACACGAAACCGGGCACGAAGGCGACCGTCAGCGTATGGCGCAAGGGTC
AGGCGCGCGATCTGCCGATCACGATCGCCGAGACGCCGGCAGAGACCACGGCGAAGGCCGAGCAGCGCAAGAACACGCCG
CAGAAGCCGCGCCAGGCAAATTCGCTTGGCTTGACGGTCAGCGACATTCCGGCGGATCAGATGAAATCGCTGAAGCTGAA
GAACGGCGTGCAGATCGACGCCGTCGACGGCCCGGCCGCCCGTGCGGGCCTGCAGCGCGGCGACATCGTGCTGCGCGTCG
GCGACACCGACATCACGAGCGCGAAGCAGTTCGCGGAAGTGACCGCGCAGCTGGATTCGCAGAAGGCGGTCGCGGTGCTC
GTGCGGCGCGGCGACAACACGCAGTTCGTGCCGGTGCGCCCGCGCCCGACGCAGAAGTAA

Upstream 100 bases:

>100_bases
TACTGGATCACCGTGCTCGGCGAAGTGCCGCCGGCCACGTTGCAGCAGTTCGCGGCTGCCATAGAATACAAGGCTTCCAA
GTAACGCTACGGCTTCCGAC

Downstream 100 bases:

>100_bases
CGCGCCGATGTTCACGCTCTACGGCCGCGGCTGGTGCCACCTGTGCGACGACATGCGCGACGCGCTGGCGCCGGTGGCGG
CCGAATCCGGCATCGAAGTC

Product: protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MTKLTLRNVFAAAVLCACLPLIPHTAVAATPPAASLPDFADLVEKVGPAVVNIRTTANVPIPGPRGALPPGFDNGDMSEF
FRRFFGIPLPQAPGNGGGNGNPKNAPAPDNPPDAEQNRGVGSGFIVSADGYVMTNAHVVDDADTIYVTLTDKREFKAKLI
GVDDRTDVAVVKIQASNLPVVAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSSKSRNTGDYLPFIQTDVAVNPGNSGG
PLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKATGKVTRGRIAVAIGEVTKDVADSIGLPKAEGALVSS
VEPGGPADKAGIQPGDIILKFNGRPVETASDLPRMVGDTKPGTKATVSVWRKGQARDLPITIAETPAETTAKAEQRKNTP
QKPRQANSLGLTVSDIPADQMKSLKLKNGVQIDAVDGPAARAGLQRGDIVLRVGDTDITSAKQFAEVTAQLDSQKAVAVL
VRRGDNTQFVPVRPRPTQK

Sequences:

>Translated_499_residues
MTKLTLRNVFAAAVLCACLPLIPHTAVAATPPAASLPDFADLVEKVGPAVVNIRTTANVPIPGPRGALPPGFDNGDMSEF
FRRFFGIPLPQAPGNGGGNGNPKNAPAPDNPPDAEQNRGVGSGFIVSADGYVMTNAHVVDDADTIYVTLTDKREFKAKLI
GVDDRTDVAVVKIQASNLPVVAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSSKSRNTGDYLPFIQTDVAVNPGNSGG
PLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKATGKVTRGRIAVAIGEVTKDVADSIGLPKAEGALVSS
VEPGGPADKAGIQPGDIILKFNGRPVETASDLPRMVGDTKPGTKATVSVWRKGQARDLPITIAETPAETTAKAEQRKNTP
QKPRQANSLGLTVSDIPADQMKSLKLKNGVQIDAVDGPAARAGLQRGDIVLRVGDTDITSAKQFAEVTAQLDSQKAVAVL
VRRGDNTQFVPVRPRPTQK
>Mature_498_residues
TKLTLRNVFAAAVLCACLPLIPHTAVAATPPAASLPDFADLVEKVGPAVVNIRTTANVPIPGPRGALPPGFDNGDMSEFF
RRFFGIPLPQAPGNGGGNGNPKNAPAPDNPPDAEQNRGVGSGFIVSADGYVMTNAHVVDDADTIYVTLTDKREFKAKLIG
VDDRTDVAVVKIQASNLPVVAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSSKSRNTGDYLPFIQTDVAVNPGNSGGP
LINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKATGKVTRGRIAVAIGEVTKDVADSIGLPKAEGALVSSV
EPGGPADKAGIQPGDIILKFNGRPVETASDLPRMVGDTKPGTKATVSVWRKGQARDLPITIAETPAETTAKAEQRKNTPQ
KPRQANSLGLTVSDIPADQMKSLKLKNGVQIDAVDGPAARAGLQRGDIVLRVGDTDITSAKQFAEVTAQLDSQKAVAVLV
RRGDNTQFVPVRPRPTQK

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=280, Percent_Identity=38.9285714285714, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI22129776, Length=262, Percent_Identity=38.9312977099237, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI24308541, Length=250, Percent_Identity=36.8, Blast_Score=158, Evalue=9e-39,
Organism=Homo sapiens, GI7019477, Length=251, Percent_Identity=39.8406374501992, Blast_Score=149, Evalue=4e-36,
Organism=Escherichia coli, GI1789629, Length=497, Percent_Identity=36.6197183098592, Blast_Score=257, Evalue=2e-69,
Organism=Escherichia coli, GI1786356, Length=485, Percent_Identity=34.639175257732, Blast_Score=248, Evalue=6e-67,
Organism=Escherichia coli, GI1789630, Length=294, Percent_Identity=38.0952380952381, Blast_Score=184, Evalue=8e-48,
Organism=Drosophila melanogaster, GI24646839, Length=262, Percent_Identity=38.9312977099237, Blast_Score=168, Evalue=9e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 52175; Mature: 52044

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLTLRNVFAAAVLCACLPLIPHTAVAATPPAASLPDFADLVEKVGPAVVNIRTTANVP
CCEEHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCHHHHHHHHCCCEEEEEEEECCCC
IPGPRGALPPGFDNGDMSEFFRRFFGIPLPQAPGNGGGNGNPKNAPAPDNPPDAEQNRGV
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCC
GSGFIVSADGYVMTNAHVVDDADTIYVTLTDKREFKAKLIGVDDRTDVAVVKIQASNLPV
CCCEEEECCCEEEECCEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEEEECCCCE
VAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSSKSRNTGDYLPFIQTDVAVNPGNSGG
EEECCCCCEEECEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEEECEEECCCCCCC
PLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKATGKVTRGRIAVAIGEV
CEEEECCCEEEECHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEEEHHH
TKDVADSIGLPKAEGALVSSVEPGGPADKAGIQPGDIILKFNGRPVETASDLPRMVGDTK
HHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCC
PGTKATVSVWRKGQARDLPITIAETPAETTAKAEQRKNTPQKPRQANSLGLTVSDIPADQ
CCCHHHHHEECCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHH
MKSLKLKNGVQIDAVDGPAARAGLQRGDIVLRVGDTDITSAKQFAEVTAQLDSQKAVAVL
HHHHHHCCCCEEEECCCCHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEE
VRRGDNTQFVPVRPRPTQK
EEECCCCEEEECCCCCCCC
>Mature Secondary Structure 
TKLTLRNVFAAAVLCACLPLIPHTAVAATPPAASLPDFADLVEKVGPAVVNIRTTANVP
CEEHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCHHHHHHHHCCCEEEEEEEECCCC
IPGPRGALPPGFDNGDMSEFFRRFFGIPLPQAPGNGGGNGNPKNAPAPDNPPDAEQNRGV
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCC
GSGFIVSADGYVMTNAHVVDDADTIYVTLTDKREFKAKLIGVDDRTDVAVVKIQASNLPV
CCCEEEECCCEEEECCEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEEEECCCCE
VAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSSKSRNTGDYLPFIQTDVAVNPGNSGG
EEECCCCCEEECEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEEECEEECCCCCCC
PLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKATGKVTRGRIAVAIGEV
CEEEECCCEEEECHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEEEHHH
TKDVADSIGLPKAEGALVSSVEPGGPADKAGIQPGDIILKFNGRPVETASDLPRMVGDTK
HHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCC
PGTKATVSVWRKGQARDLPITIAETPAETTAKAEQRKNTPQKPRQANSLGLTVSDIPADQ
CCCHHHHHEECCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHH
MKSLKLKNGVQIDAVDGPAARAGLQRGDIVLRVGDTDITSAKQFAEVTAQLDSQKAVAVL
HHHHHHCCCCEEEECCCCHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEE
VRRGDNTQFVPVRPRPTQK
EEECCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]