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The map label for this gene is fabF [H]

Identifier: 115351055

GI number: 115351055

Start: 1089742

End: 1091007

Strand: Direct

Name: fabF [H]

Synonym: Bamb_1001

Alternate gene names: 115351055

Gene position: 1089742-1091007 (Clockwise)

Preceding gene: 115351054

Following gene: 115351056

Centisome position: 30.64

GC content: 65.17

Gene sequence:

>1266_bases
TTGTTTTTGTCATCCAATGGAAAAGAGGTTACCGTGAGCCGCCGTCGTGTTGTCGTTACAGGCCTGGGGCTGATTTCGCC
CGTTGGCAATAATGTTGCCGACGGCTGGGCCAATCTCGTCGCCGGCAAGTCCGGCATCGCCACCGTCACGAAGTTCGATC
CGTCGAACCTCGCCGTGCATTTCGCGGGCGAGGTGAAGGGTTTCAGCGCCGAGGAATACATCCCGGCGAAGGAAGCCCGC
AACATGGACACGTTCATCCATTACGGCATCGCAGCCGGCGTCCAGGCAATCCGGGACAGCGGCCTCGAGGTGAACGAAGC
CAATGCGGAACGCATCGGCGTGCTGGTCGGCTCCGGCATCGGCGGCCTGCCGATGATCGAAGACACGCACCAGACCTACG
TCGATCGCGGCGCACGCCGGATTTCGCCGTTCTTCGTGCCGGGTTCGATCATCAACATGATCTCGGGTCACCTGAGCATC
ATGTTCGGCCTGAAGGGCCCGAACCTCGCGGCCGTCACGGCCTGCACGACCGGCCTGCACAGCATCGGCCTCGCGGCACG
CCTGATCCAGGCCGGCGACGCCGACGTGATGGTCGCGGGCGGCGCCGAATCGACGGTGTCGCCGCTGGGCATCGGCGGCT
TCGCGGCCGCGCGGGCGCTGTCGACCCGCAACGACGATCCGGCCACCGCGTCCCGTCCGTGGGACAAGGACCGCGACGGC
TTCGTGCTGGGCGAGGGTTCCGGCGTGATGGTGCTCGAAGAGTACGAGGCGGCGAAGGCACGCGGCGCGAAGATCTATGC
GGAAGTCTCGGGCTTCGGCATGACGGGCGACGCATACCACATGACCGCGCCGAACATGGACGGTCCGCGCCGCTGCATGG
TCGCGGCCCTGCGCGACGCCGGCGTGAACCCGGACGAGGTCCAGTACCTGAACGCGCACGGCACGTCGACGCAGCTCGGT
GACAAGAACGAGTCCGACGCGGTGAAGGCGGCATTCGGCGAGCACGCGTACAAGCTCATCGTGAACTCGACGAAGTCGAT
GACGGGCCACCTGCTGGGTGGCGCGGGTGGTCTGGAGTCGGTGTTCACGGTGCTGGCGCTGCACAACAACGTGTCGCCGC
CGACCATCAACATCTTCAACCAGGACCCCGAGTGCGATCTCGATTACTGCGCGAACACCGCGCGGGACATGAAGATCGAC
GTGGCCGTGAAGAACAACTTCGGCTTCGGTGGTACCAACGGCACGCTGGTGTTCAAGCGCGTCTGA

Upstream 100 bases:

>100_bases
CGCGATCTTCGCGATTGACGCGCCATCCTGCCGGCATTCGCGCCGGACGGACTAACAGCCGCAGGGCTCGCAGGGCTGGT
TCCTGGGGCCACTGTGGCTT

Downstream 100 bases:

>100_bases
CGTCGAAATCGCTTGACGAGTCCAATCGATGCTCCGGCCGGGCGTCCGCAGCGCTTTGCGTTGCGGGCCTCGGCCGTGTC
GTATGTCGTGCTGGCCGCGT

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MFLSSNGKEVTVSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIATVTKFDPSNLAVHFAGEVKGFSAEEYIPAKEAR
NMDTFIHYGIAAGVQAIRDSGLEVNEANAERIGVLVGSGIGGLPMIEDTHQTYVDRGARRISPFFVPGSIINMISGHLSI
MFGLKGPNLAAVTACTTGLHSIGLAARLIQAGDADVMVAGGAESTVSPLGIGGFAAARALSTRNDDPATASRPWDKDRDG
FVLGEGSGVMVLEEYEAAKARGAKIYAEVSGFGMTGDAYHMTAPNMDGPRRCMVAALRDAGVNPDEVQYLNAHGTSTQLG
DKNESDAVKAAFGEHAYKLIVNSTKSMTGHLLGGAGGLESVFTVLALHNNVSPPTINIFNQDPECDLDYCANTARDMKID
VAVKNNFGFGGTNGTLVFKRV

Sequences:

>Translated_421_residues
MFLSSNGKEVTVSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIATVTKFDPSNLAVHFAGEVKGFSAEEYIPAKEAR
NMDTFIHYGIAAGVQAIRDSGLEVNEANAERIGVLVGSGIGGLPMIEDTHQTYVDRGARRISPFFVPGSIINMISGHLSI
MFGLKGPNLAAVTACTTGLHSIGLAARLIQAGDADVMVAGGAESTVSPLGIGGFAAARALSTRNDDPATASRPWDKDRDG
FVLGEGSGVMVLEEYEAAKARGAKIYAEVSGFGMTGDAYHMTAPNMDGPRRCMVAALRDAGVNPDEVQYLNAHGTSTQLG
DKNESDAVKAAFGEHAYKLIVNSTKSMTGHLLGGAGGLESVFTVLALHNNVSPPTINIFNQDPECDLDYCANTARDMKID
VAVKNNFGFGGTNGTLVFKRV
>Mature_421_residues
MFLSSNGKEVTVSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIATVTKFDPSNLAVHFAGEVKGFSAEEYIPAKEAR
NMDTFIHYGIAAGVQAIRDSGLEVNEANAERIGVLVGSGIGGLPMIEDTHQTYVDRGARRISPFFVPGSIINMISGHLSI
MFGLKGPNLAAVTACTTGLHSIGLAARLIQAGDADVMVAGGAESTVSPLGIGGFAAARALSTRNDDPATASRPWDKDRDG
FVLGEGSGVMVLEEYEAAKARGAKIYAEVSGFGMTGDAYHMTAPNMDGPRRCMVAALRDAGVNPDEVQYLNAHGTSTQLG
DKNESDAVKAAFGEHAYKLIVNSTKSMTGHLLGGAGGLESVFTVLALHNNVSPPTINIFNQDPECDLDYCANTARDMKID
VAVKNNFGFGGTNGTLVFKRV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=423, Percent_Identity=46.5721040189125, Blast_Score=365, Evalue=1e-101,
Organism=Homo sapiens, GI223972627, Length=148, Percent_Identity=51.3513513513513, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI41872631, Length=438, Percent_Identity=23.7442922374429, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI1787337, Length=413, Percent_Identity=60.0484261501211, Blast_Score=483, Evalue=1e-138,
Organism=Escherichia coli, GI1788663, Length=411, Percent_Identity=37.956204379562, Blast_Score=241, Evalue=8e-65,
Organism=Caenorhabditis elegans, GI71983541, Length=412, Percent_Identity=35.1941747572816, Blast_Score=231, Evalue=5e-61,
Organism=Caenorhabditis elegans, GI71983535, Length=255, Percent_Identity=40, Blast_Score=178, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI212642053, Length=367, Percent_Identity=24.7956403269755, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17550940, Length=376, Percent_Identity=25.7978723404255, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320904, Length=449, Percent_Identity=36.5256124721604, Blast_Score=263, Evalue=5e-71,
Organism=Drosophila melanogaster, GI24644341, Length=415, Percent_Identity=44.3373493975904, Blast_Score=337, Evalue=1e-92,
Organism=Drosophila melanogaster, GI19920632, Length=355, Percent_Identity=25.6338028169014, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI221330659, Length=355, Percent_Identity=25.6338028169014, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24581345, Length=428, Percent_Identity=22.4299065420561, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 44081; Mature: 44081

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLSSNGKEVTVSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIATVTKFDPSNLAVH
CCCCCCCCEEEEECCEEEEEECCHHCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCEEEE
FAGEVKGFSAEEYIPAKEARNMDTFIHYGIAAGVQAIRDSGLEVNEANAERIGVLVGSGI
EECCCCCCCHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEECCC
GGLPMIEDTHQTYVDRGARRISPFFVPGSIINMISGHLSIMFGLKGPNLAAVTACTTGLH
CCCCCCCCHHHHHHHCCHHHCCCEECCHHHHHHHCCCEEEEEECCCCCEEEEHHHHHHHH
SIGLAARLIQAGDADVMVAGGAESTVSPLGIGGFAAARALSTRNDDPATASRPWDKDRDG
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
FVLGEGSGVMVLEEYEAAKARGAKIYAEVSGFGMTGDAYHMTAPNMDGPRRCMVAALRDA
EEEECCCCEEEEECCCHHHCCCCEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHC
GVNPDEVQYLNAHGTSTQLGDKNESDAVKAAFGEHAYKLIVNSTKSMTGHLLGGAGGLES
CCCHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHCEEEEEEECCCCCCEEEECCCCCHHH
VFTVLALHNNVSPPTINIFNQDPECDLDYCANTARDMKIDVAVKNNFGFGGTNGTLVFKR
HHHHHHHHCCCCCCEEEEECCCCCCCHHHHCCCCCCEEEEEEEECCCCCCCCCCEEEEEE
V
C
>Mature Secondary Structure
MFLSSNGKEVTVSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIATVTKFDPSNLAVH
CCCCCCCCEEEEECCEEEEEECCHHCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCEEEE
FAGEVKGFSAEEYIPAKEARNMDTFIHYGIAAGVQAIRDSGLEVNEANAERIGVLVGSGI
EECCCCCCCHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEECCC
GGLPMIEDTHQTYVDRGARRISPFFVPGSIINMISGHLSIMFGLKGPNLAAVTACTTGLH
CCCCCCCCHHHHHHHCCHHHCCCEECCHHHHHHHCCCEEEEEECCCCCEEEEHHHHHHHH
SIGLAARLIQAGDADVMVAGGAESTVSPLGIGGFAAARALSTRNDDPATASRPWDKDRDG
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
FVLGEGSGVMVLEEYEAAKARGAKIYAEVSGFGMTGDAYHMTAPNMDGPRRCMVAALRDA
EEEECCCCEEEEECCCHHHCCCCEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHC
GVNPDEVQYLNAHGTSTQLGDKNESDAVKAAFGEHAYKLIVNSTKSMTGHLLGGAGGLES
CCCHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHCEEEEEEECCCCCCEEEECCCCCHHH
VFTVLALHNNVSPPTINIFNQDPECDLDYCANTARDMKIDVAVKNNFGFGGTNGTLVFKR
HHHHHHHHCCCCCCEEEEECCCCCCCHHHHCCCCCCEEEEEEEECCCCCCCCCCEEEEEE
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]