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The map label for this gene is fabD [H]

Identifier: 115351052

GI number: 115351052

Start: 1087510

End: 1088442

Strand: Direct

Name: fabD [H]

Synonym: Bamb_0998

Alternate gene names: 115351052

Gene position: 1087510-1088442 (Clockwise)

Preceding gene: 115351051

Following gene: 115351053

Centisome position: 30.58

GC content: 68.7

Gene sequence:

>933_bases
ATGAAATTTGCATTCGTTTTTCCGGGGCAGGGCTCGCAGTCGGTCGGCATGCTCAACGCATTCGCCGATCTGGCCGTCGT
GCGCGAGACGCTCCAGGAAGCATCCGATGCACTCAATCAGGATATCGGCAAGCTGATCGCCGAAGGTCCGGCCGAAGAGC
TGAATCTGACCACCAACACGCAGCCGGTGATGCTGACGGCCGCCTACGCGTGCTATCGCGCGTGGCAGCAGGCCGGCGGC
CCGGCGCCGTCGATCGTCGCGGGCCACAGCCTCGGCGAATACACGGCGCTCGTCGCGGCAGGCGCGATCGCGTTCAAGGA
CGCGGTGCCGCTCGTGCGCTTCCGTGCGCAGGCGATGCAGACGGCCGTGCCGGTCGGCCAGGGCGGCATGGCCGCGATCC
TGGGCCTCGATGACGATACGGTGCGCGCGGTGTGCGCCGAAGCCGCGGCAGCGGGCGTCGTCGAAGCCGTGAACTTCAAC
GCGCCGGCGCAGGTCGTGATCGCGGGCGCGAAGGCGGCCGTCGAGAAGGCGTGCGAAATCGCGAAGGCGAAGGGCGCGAA
GCGCGCGCTGCCGCTGCCGGTGTCGGCGCCGTTCCATTCGTCGTTGCTCAAGCCGGCGTCGGACCAGTTGCGCGACTATC
TCGCGAGCGTCGACGTGAAGGCGCCGCAGATTCCGGTCGTCAACAACATCGACGTCGCGGTGGTCAGCGATCCGGCCGCG
ATCAAGGACGCGCTGGTGCGCCAGGCCGCGGGCCCCGTGCGCTGGGTCGAATGCGTGCAGCACATCGCGGGCACGGGCGT
CACGCACGTGATCGAATGCGGTCCGGGCAAGGTGCTGGCGGGCCTCACGAAGCGCATCGACGGCAACCTGGTCGGCGCCT
CGGTGTTCGATCCGGCTTCGCTCGACGAAGCACTGAAGCTGGCGACCGCCTGA

Upstream 100 bases:

>100_bases
GTCTTCCGCTTCTGATCCGCGGCGCGCGACTGCCGCGCGCGGCTCCCAAACCGGCGCGCCGTTCGCGCGCGCCGTTCGAA
TCGATTCAATTGGGGACGAT

Downstream 100 bases:

>100_bases
CGCGGCGCCTTTCCTCAAGAGACGGATATTCGATTCATGGAAAAGACTCTCGATAAACAGGTCGCGATCGTGACCGGCGC
ATCGCGCGGCATCGGCCGTG

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKFAFVFPGQGSQSVGMLNAFADLAVVRETLQEASDALNQDIGKLIAEGPAEELNLTTNTQPVMLTAAYACYRAWQQAGG
PAPSIVAGHSLGEYTALVAAGAIAFKDAVPLVRFRAQAMQTAVPVGQGGMAAILGLDDDTVRAVCAEAAAAGVVEAVNFN
APAQVVIAGAKAAVEKACEIAKAKGAKRALPLPVSAPFHSSLLKPASDQLRDYLASVDVKAPQIPVVNNIDVAVVSDPAA
IKDALVRQAAGPVRWVECVQHIAGTGVTHVIECGPGKVLAGLTKRIDGNLVGASVFDPASLDEALKLATA

Sequences:

>Translated_310_residues
MKFAFVFPGQGSQSVGMLNAFADLAVVRETLQEASDALNQDIGKLIAEGPAEELNLTTNTQPVMLTAAYACYRAWQQAGG
PAPSIVAGHSLGEYTALVAAGAIAFKDAVPLVRFRAQAMQTAVPVGQGGMAAILGLDDDTVRAVCAEAAAAGVVEAVNFN
APAQVVIAGAKAAVEKACEIAKAKGAKRALPLPVSAPFHSSLLKPASDQLRDYLASVDVKAPQIPVVNNIDVAVVSDPAA
IKDALVRQAAGPVRWVECVQHIAGTGVTHVIECGPGKVLAGLTKRIDGNLVGASVFDPASLDEALKLATA
>Mature_310_residues
MKFAFVFPGQGSQSVGMLNAFADLAVVRETLQEASDALNQDIGKLIAEGPAEELNLTTNTQPVMLTAAYACYRAWQQAGG
PAPSIVAGHSLGEYTALVAAGAIAFKDAVPLVRFRAQAMQTAVPVGQGGMAAILGLDDDTVRAVCAEAAAAGVVEAVNFN
APAQVVIAGAKAAVEKACEIAKAKGAKRALPLPVSAPFHSSLLKPASDQLRDYLASVDVKAPQIPVVNNIDVAVVSDPAA
IKDALVRQAAGPVRWVECVQHIAGTGVTHVIECGPGKVLAGLTKRIDGNLVGASVFDPASLDEALKLATA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=301, Percent_Identity=32.2259136212625, Blast_Score=144, Evalue=1e-34,
Organism=Escherichia coli, GI1787334, Length=307, Percent_Identity=56.6775244299674, Blast_Score=319, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI71984332, Length=272, Percent_Identity=30.5147058823529, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17550940, Length=294, Percent_Identity=29.5918367346939, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI212642053, Length=292, Percent_Identity=27.0547945205479, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24665753, Length=308, Percent_Identity=31.1688311688312, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31751; Mature: 31751

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAFVFPGQGSQSVGMLNAFADLAVVRETLQEASDALNQDIGKLIAEGPAEELNLTTNT
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCC
QPVMLTAAYACYRAWQQAGGPAPSIVAGHSLGEYTALVAAGAIAFKDAVPLVRFRAQAMQ
CCHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVPVGQGGMAAILGLDDDTVRAVCAEAAAAGVVEAVNFNAPAQVVIAGAKAAVEKACEI
HHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHH
AKAKGAKRALPLPVSAPFHSSLLKPASDQLRDYLASVDVKAPQIPVVNNIDVAVVSDPAA
HHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCHH
IKDALVRQAAGPVRWVECVQHIAGTGVTHVIECGPGKVLAGLTKRIDGNLVGASVFDPAS
HHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCEECCCCCCCHH
LDEALKLATA
HHHHHHHHCC
>Mature Secondary Structure
MKFAFVFPGQGSQSVGMLNAFADLAVVRETLQEASDALNQDIGKLIAEGPAEELNLTTNT
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCC
QPVMLTAAYACYRAWQQAGGPAPSIVAGHSLGEYTALVAAGAIAFKDAVPLVRFRAQAMQ
CCHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVPVGQGGMAAILGLDDDTVRAVCAEAAAAGVVEAVNFNAPAQVVIAGAKAAVEKACEI
HHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHH
AKAKGAKRALPLPVSAPFHSSLLKPASDQLRDYLASVDVKAPQIPVVNNIDVAVVSDPAA
HHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCHH
IKDALVRQAAGPVRWVECVQHIAGTGVTHVIECGPGKVLAGLTKRIDGNLVGASVFDPAS
HHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCEECCCCCCCHH
LDEALKLATA
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]