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The map label for this gene is cysM

Identifier: 115350985

GI number: 115350985

Start: 1023449

End: 1024351

Strand: Direct

Name: cysM

Synonym: Bamb_0931

Alternate gene names: 115350985

Gene position: 1023449-1024351 (Clockwise)

Preceding gene: 115350984

Following gene: 115350987

Centisome position: 28.78

GC content: 64.89

Gene sequence:

>903_bases
ATGGCTTACAAAACTATCGAAGACACGATCGGCAACACGCCGCTCGTGCAACTGGTCCGCCTGCCGGACGACGAGATTCG
CGCACGCAACAACGTGGTGCTCGCCAAGCTGGAAGGCAACAATCCGGCAGGGTCCGTGAAGGATCGCCCGGCGCTGTCGA
TGATCAGCAAGGCCGAGGCGCGCGGTCGCATCAAGCCGGGCGATACGCTGATCGAGGCGACGAGCGGCAACACCGGCATC
GCGCTCGCGATGGCCGCGGCAATCCGTGGCTACAAGATGGTGCTGGTCATGCCCGAGGATCTGTCGGTCGAGCGTCGCCA
GAGCATGGCCGCTTACGGCGCCGAAATCATCCTGACGCCGGTAAAGGGCGGGATGGAACTGGCGCGCGACCTCGCGGAGC
AAATGCAGCGCGAAGGCAAGGGCGTGATCCTCGATCAGTTCGGGAACCCCGACAATCCGGTCGCGCACTACGAAGGAACG
GGCCCGGAGATCTGGCGCGACACCGAAGGGCGCATCACGCACTTCGTATCGGCGATGGGCACGACGGGCACGATCATGGG
CACGTCGCGCTATCTGAAGGAACAGAATCCGGCGATCGAGATCGTCGGCGCGCAGCCGGAAGAAGGGTCGCGCATTCCGG
GCATTCGCAAATGGCCGGAAGCCTACATGCCGACGATCTTCGATCGCAGCCGCGTCGATCGCGTCGAGAGCGTGAGCCAG
GCCGCGTCGGAGACGATGGCGCGCCGGCTCGCGGCCGTCGAAGGCATCTTTGCCGGCATTTCGTCGGGCGGCGCATGCGA
AGTCGCGATGCGCATCGCTCGCCAGGTCGAGAACGCGACGATCGTGTTCATCGTCTGCGACCGCGGCGACCGCTATCTGT
CGACCGGCGTGTTTCCTGCCTGA

Upstream 100 bases:

>100_bases
GCGGCAGACCTATTCCATCGTCGCGATGGGGTTGCCGGCGCGCGCCCCCGCGCTGGTTTACAATCGATTGATTGATCTGC
CTCGCACTCACGGTATCTCC

Downstream 100 bases:

>100_bases
GCCCGATCGGCGTCCGCTGCGTCGAACGATAAAAAAACGCCGCATGAGCGGCGTTTTTTCTTTGCGCGGGCCGGGCTTAC
TGCGCCGGCGTCTCCGTATC

Product: cysteine synthase B

Products: NA

Alternate protein names: CSase B; O-acetylserine (thiol)-lyase B; OAS-TL B; O-acetylserine sulfhydrylase B [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MAYKTIEDTIGNTPLVQLVRLPDDEIRARNNVVLAKLEGNNPAGSVKDRPALSMISKAEARGRIKPGDTLIEATSGNTGI
ALAMAAAIRGYKMVLVMPEDLSVERRQSMAAYGAEIILTPVKGGMELARDLAEQMQREGKGVILDQFGNPDNPVAHYEGT
GPEIWRDTEGRITHFVSAMGTTGTIMGTSRYLKEQNPAIEIVGAQPEEGSRIPGIRKWPEAYMPTIFDRSRVDRVESVSQ
AASETMARRLAAVEGIFAGISSGGACEVAMRIARQVENATIVFIVCDRGDRYLSTGVFPA

Sequences:

>Translated_300_residues
MAYKTIEDTIGNTPLVQLVRLPDDEIRARNNVVLAKLEGNNPAGSVKDRPALSMISKAEARGRIKPGDTLIEATSGNTGI
ALAMAAAIRGYKMVLVMPEDLSVERRQSMAAYGAEIILTPVKGGMELARDLAEQMQREGKGVILDQFGNPDNPVAHYEGT
GPEIWRDTEGRITHFVSAMGTTGTIMGTSRYLKEQNPAIEIVGAQPEEGSRIPGIRKWPEAYMPTIFDRSRVDRVESVSQ
AASETMARRLAAVEGIFAGISSGGACEVAMRIARQVENATIVFIVCDRGDRYLSTGVFPA
>Mature_299_residues
AYKTIEDTIGNTPLVQLVRLPDDEIRARNNVVLAKLEGNNPAGSVKDRPALSMISKAEARGRIKPGDTLIEATSGNTGIA
LAMAAAIRGYKMVLVMPEDLSVERRQSMAAYGAEIILTPVKGGMELARDLAEQMQREGKGVILDQFGNPDNPVAHYEGTG
PEIWRDTEGRITHFVSAMGTTGTIMGTSRYLKEQNPAIEIVGAQPEEGSRIPGIRKWPEAYMPTIFDRSRVDRVESVSQA
ASETMARRLAAVEGIFAGISSGGACEVAMRIARQVENATIVFIVCDRGDRYLSTGVFPA

Specific function: Two Cysteine Synthase Enzymes Are Found. Both Catalyze The Same Reaction. Cysteine Synthase B Can Also Use Thiosulfate In Place Of Sulfide To Give Cysteine Thiosulfonate As A Product. [C]

COG id: COG0031

COG function: function code E; Cysteine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cysteine synthase/cystathionine beta- synthase family [H]

Homologues:

Organism=Homo sapiens, GI295821202, Length=302, Percent_Identity=38.4105960264901, Blast_Score=185, Evalue=5e-47,
Organism=Homo sapiens, GI295821200, Length=302, Percent_Identity=38.4105960264901, Blast_Score=185, Evalue=5e-47,
Organism=Homo sapiens, GI4557415, Length=302, Percent_Identity=38.4105960264901, Blast_Score=185, Evalue=5e-47,
Organism=Escherichia coli, GI2367138, Length=295, Percent_Identity=63.0508474576271, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI1788754, Length=317, Percent_Identity=42.2712933753943, Blast_Score=200, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI17562970, Length=302, Percent_Identity=44.0397350993377, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17535051, Length=305, Percent_Identity=42.2950819672131, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI32566674, Length=297, Percent_Identity=44.7811447811448, Blast_Score=217, Evalue=8e-57,
Organism=Caenorhabditis elegans, GI115535073, Length=300, Percent_Identity=40.6666666666667, Blast_Score=205, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17561720, Length=302, Percent_Identity=41.7218543046358, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI25147552, Length=318, Percent_Identity=36.1635220125786, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17534315, Length=317, Percent_Identity=36.9085173501577, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI32566672, Length=212, Percent_Identity=39.1509433962264, Blast_Score=143, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6321594, Length=316, Percent_Identity=39.873417721519, Blast_Score=185, Evalue=7e-48,
Organism=Saccharomyces cerevisiae, GI6321449, Length=333, Percent_Identity=32.1321321321321, Blast_Score=126, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24643623, Length=311, Percent_Identity=39.5498392282958, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI20129101, Length=311, Percent_Identity=39.5498392282958, Blast_Score=179, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001216
- InterPro:   IPR005856
- InterPro:   IPR005858
- InterPro:   IPR001926 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =2.5.1.47 [H]

Molecular weight: Translated: 32452; Mature: 32320

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00901 CYS_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYKTIEDTIGNTPLVQLVRLPDDEIRARNNVVLAKLEGNNPAGSVKDRPALSMISKAEA
CCCCCHHHHCCCCCCEEEEECCCHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHH
RGRIKPGDTLIEATSGNTGIALAMAAAIRGYKMVLVMPEDLSVERRQSMAAYGAEIILTP
CCCCCCCCEEEEECCCCCCHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEE
VKGGMELARDLAEQMQREGKGVILDQFGNPDNPVAHYEGTGPEIWRDTEGRITHFVSAMG
CCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEECCCCCCCEECCCCHHHHHHHHHC
TTGTIMGTSRYLKEQNPAIEIVGAQPEEGSRIPGIRKWPEAYMPTIFDRSRVDRVESVSQ
CCCEEECCHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHH
AASETMARRLAAVEGIFAGISSGGACEVAMRIARQVENATIVFIVCDRGDRYLSTGVFPA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEECCCCCCC
>Mature Secondary Structure 
AYKTIEDTIGNTPLVQLVRLPDDEIRARNNVVLAKLEGNNPAGSVKDRPALSMISKAEA
CCCCHHHHCCCCCCEEEEECCCHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHH
RGRIKPGDTLIEATSGNTGIALAMAAAIRGYKMVLVMPEDLSVERRQSMAAYGAEIILTP
CCCCCCCCEEEEECCCCCCHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEE
VKGGMELARDLAEQMQREGKGVILDQFGNPDNPVAHYEGTGPEIWRDTEGRITHFVSAMG
CCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEECCCCCCCEECCCCHHHHHHHHHC
TTGTIMGTSRYLKEQNPAIEIVGAQPEEGSRIPGIRKWPEAYMPTIFDRSRVDRVESVSQ
CCCEEECCHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHH
AASETMARRLAAVEGIFAGISSGGACEVAMRIARQVENATIVFIVCDRGDRYLSTGVFPA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]