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The map label for this gene is hldD [H]

Identifier: 115350983

GI number: 115350983

Start: 1021853

End: 1022845

Strand: Direct

Name: hldD [H]

Synonym: Bamb_0929

Alternate gene names: 115350983

Gene position: 1021853-1022845 (Clockwise)

Preceding gene: 115350982

Following gene: 115350984

Centisome position: 28.73

GC content: 63.65

Gene sequence:

>993_bases
ATGACCGTCATCGTCACCGGCGCAGCCGGTTTTATCGGCGCGAACATCGTCAAGGCGCTCAACGAGCGCGGCGAGTCGCG
CATCATCGCGGTCGACAATCTGACGCGCGCGGACAAGTTCCGCAACCTCGTCGATTGCGAGATCGACGACTATCTCGACA
AGACGGAATTCGTCGAACGCTTCACGCGCGGCGATTTCGGCAAGGTACGCGCGGTGTTCCACGAAGGCGCCTGTTCGGAC
ACGATGGAAACCGACGGCCGCTACATGATGGACAACAACTTCCGCTACAGCCGCGCGGTGCTCGATGCGTGCCTCGCGCA
GGGCGCGCAGTTCCTGTACGCGTCGTCGGCCGCGATCTACGGCGGCTCGACGCGGTTCGTCGAGGAGCGCGAGGTCGAGG
CGCCGCTGAACGTCTACGGCTATTCGAAGTTCCTGTTCGACCAGGTGATCCGCCGCGTGCTGCCGAGCGCGAAGAGCCAG
ATCGCCGGGTTTCGCTACTTCAACGTGTACGGCCCGCGCGAGACGCACAAGGGCCGCATGGCATCGGTCGCGTTCCACAA
CTTCAACCAGTTCCGCGCGGAAGGCAAGGTCAAGCTGTTCGGCGAGTACAACGGTTATGCGCCGGGCGAGCAGACGCGCG
ATTTCGTGTCGGTCGAGGACGTCGCGAAAGTGAACCTGTTCTTCTTCGATCATCCGGAGAAGTCGGGCATCTTCAACCTC
GGCACCGGCCGTGCGCAGCCGTTCAACGACATCGCATCGACGGTCGTGAACACGTTGCGCGCGCTCGACAACCTGCCGCC
GCTGACGCTCGCGCAGCAGGTCGAGCAAGGGCTGATCGAATACGTGGCGTTCCCCGACGCGCTGCGCGGCAAGTACCAGT
GCTTCACGCAGGCCGACCAGACGAAGCTGCGCAGTGCCGGCTACGATGCGCCGTTCCTGACGGTGCAGGAAGGTGTCGAC
CGCTACGTGCGTTGGCTGTCCGGCCAGGTTTAA

Upstream 100 bases:

>100_bases
AAGCTCGGTACGGCCACGGTAGACTACGACGAACTGTTTCACTGAGTGCATTCGGCGGCGCGCCGCGCGGATGTCTCGCA
ATTTTTCAGGCAGAACGATC

Downstream 100 bases:

>100_bases
ACGCACGCGCTGCGTCGCTAGACTGGGTCTCACGGTCGGCAGCCGCCGATCGTTTTCATCGGAGATCCAGCACATGATCA
AAAAATGGTTTGCCGCGGCC

Product: ADP-L-glycero-D-manno-heptose-6-epimerase

Products: NA

Alternate protein names: ADP-L-glycero-beta-D-manno-heptose-6-epimerase; ADP-glyceromanno-heptose 6-epimerase; ADP-hep 6-epimerase; AGME [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTVIVTGAAGFIGANIVKALNERGESRIIAVDNLTRADKFRNLVDCEIDDYLDKTEFVERFTRGDFGKVRAVFHEGACSD
TMETDGRYMMDNNFRYSRAVLDACLAQGAQFLYASSAAIYGGSTRFVEEREVEAPLNVYGYSKFLFDQVIRRVLPSAKSQ
IAGFRYFNVYGPRETHKGRMASVAFHNFNQFRAEGKVKLFGEYNGYAPGEQTRDFVSVEDVAKVNLFFFDHPEKSGIFNL
GTGRAQPFNDIASTVVNTLRALDNLPPLTLAQQVEQGLIEYVAFPDALRGKYQCFTQADQTKLRSAGYDAPFLTVQEGVD
RYVRWLSGQV

Sequences:

>Translated_330_residues
MTVIVTGAAGFIGANIVKALNERGESRIIAVDNLTRADKFRNLVDCEIDDYLDKTEFVERFTRGDFGKVRAVFHEGACSD
TMETDGRYMMDNNFRYSRAVLDACLAQGAQFLYASSAAIYGGSTRFVEEREVEAPLNVYGYSKFLFDQVIRRVLPSAKSQ
IAGFRYFNVYGPRETHKGRMASVAFHNFNQFRAEGKVKLFGEYNGYAPGEQTRDFVSVEDVAKVNLFFFDHPEKSGIFNL
GTGRAQPFNDIASTVVNTLRALDNLPPLTLAQQVEQGLIEYVAFPDALRGKYQCFTQADQTKLRSAGYDAPFLTVQEGVD
RYVRWLSGQV
>Mature_329_residues
TVIVTGAAGFIGANIVKALNERGESRIIAVDNLTRADKFRNLVDCEIDDYLDKTEFVERFTRGDFGKVRAVFHEGACSDT
METDGRYMMDNNFRYSRAVLDACLAQGAQFLYASSAAIYGGSTRFVEEREVEAPLNVYGYSKFLFDQVIRRVLPSAKSQI
AGFRYFNVYGPRETHKGRMASVAFHNFNQFRAEGKVKLFGEYNGYAPGEQTRDFVSVEDVAKVNLFFFDHPEKSGIFNLG
TGRAQPFNDIASTVVNTLRALDNLPPLTLAQQVEQGLIEYVAFPDALRGKYQCFTQADQTKLRSAGYDAPFLTVQEGVDR
YVRWLSGQV

Specific function: Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose [H]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family. HldD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790049, Length=327, Percent_Identity=56.5749235474006, Blast_Score=349, Evalue=2e-97,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR011912
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.20 [H]

Molecular weight: Translated: 37060; Mature: 36929

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVIVTGAAGFIGANIVKALNERGESRIIAVDNLTRADKFRNLVDCEIDDYLDKTEFVER
CEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCHHHHCCHHHHHHH
FTRGDFGKVRAVFHEGACSDTMETDGRYMMDNNFRYSRAVLDACLAQGAQFLYASSAAIY
HHCCCHHHHHHHHHCCCCCCCHHCCCCEEECCCCHHHHHHHHHHHHCCCCEEEECCEEEE
GGSTRFVEEREVEAPLNVYGYSKFLFDQVIRRVLPSAKSQIAGFRYFNVYGPRETHKGRM
CCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEEECCCCCCCCCCE
ASVAFHNFNQFRAEGKVKLFGEYNGYAPGEQTRDFVSVEDVAKVNLFFFDHPEKSGIFNL
EHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHCHHHHHEEEEEEEECCCCCCEEEC
GTGRAQPFNDIASTVVNTLRALDNLPPLTLAQQVEQGLIEYVAFPDALRGKYQCFTQADQ
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHH
TKLRSAGYDAPFLTVQEGVDRYVRWLSGQV
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TVIVTGAAGFIGANIVKALNERGESRIIAVDNLTRADKFRNLVDCEIDDYLDKTEFVER
EEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCHHHHCCHHHHHHH
FTRGDFGKVRAVFHEGACSDTMETDGRYMMDNNFRYSRAVLDACLAQGAQFLYASSAAIY
HHCCCHHHHHHHHHCCCCCCCHHCCCCEEECCCCHHHHHHHHHHHHCCCCEEEECCEEEE
GGSTRFVEEREVEAPLNVYGYSKFLFDQVIRRVLPSAKSQIAGFRYFNVYGPRETHKGRM
CCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEEECCCCCCCCCCE
ASVAFHNFNQFRAEGKVKLFGEYNGYAPGEQTRDFVSVEDVAKVNLFFFDHPEKSGIFNL
EHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHCHHHHHEEEEEEEECCCCCCEEEC
GTGRAQPFNDIASTVVNTLRALDNLPPLTLAQQVEQGLIEYVAFPDALRGKYQCFTQADQ
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHH
TKLRSAGYDAPFLTVQEGVDRYVRWLSGQV
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA