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The map label for this gene is xdhA [H]

Identifier: 115350766

GI number: 115350766

Start: 792070

End: 794433

Strand: Direct

Name: xdhA [H]

Synonym: Bamb_0712

Alternate gene names: 115350766

Gene position: 792070-794433 (Clockwise)

Preceding gene: 115350765

Following gene: 115350767

Centisome position: 22.27

GC content: 68.7

Gene sequence:

>2364_bases
ATGAACCAGCAAGCAGAACCGTTCCTGAACACCCTCGACCAGCAAGCCGACGCCGCGCAGGTGCACATCTCGCGTCCGCA
CGAATCCGCCCATCTGCACGTGAGCGGGCGCGCGACCTACACCGACGACATCCCGATCGTCGCCGGCACGCTGCACGCGG
CGCTCGGGTTGTCGGCCAAACCGCACGCGAAGATCGTGTCGATGAACTTCGATGCGGTGCGCGCGACGCCGGGCGTGGTC
GCCGTGTTCACGGCCGACGACATCCCGGGCGTCAACGACTGCGGCCCGATCATCCACGACGACCCGGTGCTCGCGAAAGG
CATCGTGCAGTTCGTCGGCCAGCCGATGTTCATCGTCGTCGCGACGTCGCATGACATCGCGCGGCTCGCCGCGCGCCGCG
CGCAGGTCGACTACGAGGAGCTGCCCGCGATCCTGACCGCGCAGGAAGCGCGCCAGGCCGAAACCTACGTGATCCCGCCG
CTGAAGCTCGCGCGCGGCGACGCGGCCGCGCGCCTGGCTGCCGCGCCGCATCGCGAGTCGGGCGAGATGCTGCTCGGCGG
CCAGGAGCAGTTCTATCTGGAAGGGCAGATTGCCTACGCGGTGCCGAAGGACGACGACGGGATGCACGTGTACTGCTCGA
CGCAGCACCCGAGCGAAATGCAGCACCTCGTCGCGCACGTGCTCGGCGTCGCGTCGCACAACGTGCTGGTCGAATGTCGC
CGGATGGGCGGCGGCTTCGGCGGCAAGGAATCGCAGTCGGGCCTGTTCGCATGCTGCGCGGCGCTCGCCGCGTGGAAGCT
GCTGTGCCCGGTGAAGCTGCGCCCGGACCGCGACGACGACATGCTGATCACCGGCAAGCGGCACGACTTCCATTACCGCT
TCGACGTCGGTTACGACGACGACGGCCGCCTCGACGGCGTCGCGCTCGAGATGACGTCGCGCTGCGGCTTCTCGGCCGAC
CTGTCGGGCCCGGTGATGACGCGCGCGGTGTGCCACTTCGACAACGCGTACTGGCTCGGCGACGTCGACATCGCCGGCTA
CTGCGGCAAGACCAACACGCAGTCGAACACCGCGTTCCGCGGCTTCGGCGGCCCGCAGGGCGCGTTCGCGATCGAGTACA
TCCTCGACGACATCGCGCGCGCGCTCGGCCGCGATCCGCTCGACGTGCGCTACGCGAACCTGTACGGCAAGACCGAACGC
AACGTGACGCCTTACGGGCAGACGGTCGAGGACAACGTGCTGCAGGAGCTGCTCGGCGAACTCGAGACGACGAGCGACTA
CCGCGCGCGGCGCGCGGGCGTGCGCGACTTCAACGCCCGCAACACGGTGCTGAAGAAGGGCATCGCGCTCACGCCGGTGA
AGTTCGGCATCGCGTTCAACGTCACGCACTTCAACCAGGCCGGCGCGCTGGTGCACATCTATACCGACGGCTCGGTGCTC
GTGAACCACGGCGGCACGGAGATGGGGCAGGGGCTCAACACGAAGGTCGCGCAGGTCGTCGCGCACGAGCTCGGCATCCG
CTTCGGCCGGATCCGCGTGACGGCGACCGACACGAGCAAGGTCGCGAACACGTCCGCGACGGCCGCGTCGACGGGCTCCG
ACCTGAACGGCAAGGCCGCGCAGGATGCGGCGCGCCAGCTGCGCGAGCGGCTCGCGGTGTTCGCGGCGAAGCAGTTCGGC
GACGGCAAGGTCGATGCGGCCGACGTGAAGTTCGGCAACGACTTCGTGTGGGTCGGCGGCGCGAGCGTGCCGTTCGGCGA
GGTGATCGCGAAGGCGTATCTGGCGCGCGTGCAGCTGTGGTCCGACGGCTTCTATGCGACGCCGAAGCTGTACTGGGATC
AGTCGAAGCTGCAGGGCCGGCCGTTCTACTACTACTCGTACGGCGCGGCCGTGTCGGAAGTCGTGATCGATACGCTGACG
GGCGAGATGCGCACGCTGCGCGTCGATGCGCTGCACGACGTCGGCGCGTCGCTGAACCCGGCGCTCGACATCGGCCAGGT
CGAAGGCGCGTTCATCCAGGGGATGGGCTGGCTCACGACCGAGGAGCTGTGGTGGAACGCGGGCGGCAAGCTGATGACGC
ACGCGCCGTCCACGTACAAGATCCCGACGGTCAACGACACGCCGCCCGAGTTCAACGTGCGGCTGTTCCAGAACCGCAAC
GTGGAGGACAGCATCCATCGTTCGAAGGCCGTCGGCGAGCCGCCGCTGCTGCTGCCGTTCTCGGTGTTCTTCGCGGTGCG
CGACGCCATTGCCGCGGTCGGCGACTATCAGGTGAATCCGCCGCTCGACGCGCCGGCCACCGGCGAGTCGATCCTGCGTG
CGGTGAACGCGGTGCGTGCGGCAAGCGCCGCGCGGGCAGGTTGA

Upstream 100 bases:

>100_bases
GCACGACCCGCTGCCGCCGCAAGCCGTGAATGTGCGCGAAGTGGCCGCCGAAGCCGGCGCCGACGCCGACGCGCGCGTCT
GAAGACGGAGAACACCGAAC

Downstream 100 bases:

>100_bases
GATGAAACGACGCCCATGCTCACTTCATTCGCTGCTTCCCGAGGAGGCGGTCAGCCACCTTGGGCCGGCTCGGCGGAGGC
TGACATGAACGCACCTGTTC

Product: xanthine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 787; Mature: 787

Protein sequence:

>787_residues
MNQQAEPFLNTLDQQADAAQVHISRPHESAHLHVSGRATYTDDIPIVAGTLHAALGLSAKPHAKIVSMNFDAVRATPGVV
AVFTADDIPGVNDCGPIIHDDPVLAKGIVQFVGQPMFIVVATSHDIARLAARRAQVDYEELPAILTAQEARQAETYVIPP
LKLARGDAAARLAAAPHRESGEMLLGGQEQFYLEGQIAYAVPKDDDGMHVYCSTQHPSEMQHLVAHVLGVASHNVLVECR
RMGGGFGGKESQSGLFACCAALAAWKLLCPVKLRPDRDDDMLITGKRHDFHYRFDVGYDDDGRLDGVALEMTSRCGFSAD
LSGPVMTRAVCHFDNAYWLGDVDIAGYCGKTNTQSNTAFRGFGGPQGAFAIEYILDDIARALGRDPLDVRYANLYGKTER
NVTPYGQTVEDNVLQELLGELETTSDYRARRAGVRDFNARNTVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGSVL
VNHGGTEMGQGLNTKVAQVVAHELGIRFGRIRVTATDTSKVANTSATAASTGSDLNGKAAQDAARQLRERLAVFAAKQFG
DGKVDAADVKFGNDFVWVGGASVPFGEVIAKAYLARVQLWSDGFYATPKLYWDQSKLQGRPFYYYSYGAAVSEVVIDTLT
GEMRTLRVDALHDVGASLNPALDIGQVEGAFIQGMGWLTTEELWWNAGGKLMTHAPSTYKIPTVNDTPPEFNVRLFQNRN
VEDSIHRSKAVGEPPLLLPFSVFFAVRDAIAAVGDYQVNPPLDAPATGESILRAVNAVRAASAARAG

Sequences:

>Translated_787_residues
MNQQAEPFLNTLDQQADAAQVHISRPHESAHLHVSGRATYTDDIPIVAGTLHAALGLSAKPHAKIVSMNFDAVRATPGVV
AVFTADDIPGVNDCGPIIHDDPVLAKGIVQFVGQPMFIVVATSHDIARLAARRAQVDYEELPAILTAQEARQAETYVIPP
LKLARGDAAARLAAAPHRESGEMLLGGQEQFYLEGQIAYAVPKDDDGMHVYCSTQHPSEMQHLVAHVLGVASHNVLVECR
RMGGGFGGKESQSGLFACCAALAAWKLLCPVKLRPDRDDDMLITGKRHDFHYRFDVGYDDDGRLDGVALEMTSRCGFSAD
LSGPVMTRAVCHFDNAYWLGDVDIAGYCGKTNTQSNTAFRGFGGPQGAFAIEYILDDIARALGRDPLDVRYANLYGKTER
NVTPYGQTVEDNVLQELLGELETTSDYRARRAGVRDFNARNTVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGSVL
VNHGGTEMGQGLNTKVAQVVAHELGIRFGRIRVTATDTSKVANTSATAASTGSDLNGKAAQDAARQLRERLAVFAAKQFG
DGKVDAADVKFGNDFVWVGGASVPFGEVIAKAYLARVQLWSDGFYATPKLYWDQSKLQGRPFYYYSYGAAVSEVVIDTLT
GEMRTLRVDALHDVGASLNPALDIGQVEGAFIQGMGWLTTEELWWNAGGKLMTHAPSTYKIPTVNDTPPEFNVRLFQNRN
VEDSIHRSKAVGEPPLLLPFSVFFAVRDAIAAVGDYQVNPPLDAPATGESILRAVNAVRAASAARAG
>Mature_787_residues
MNQQAEPFLNTLDQQADAAQVHISRPHESAHLHVSGRATYTDDIPIVAGTLHAALGLSAKPHAKIVSMNFDAVRATPGVV
AVFTADDIPGVNDCGPIIHDDPVLAKGIVQFVGQPMFIVVATSHDIARLAARRAQVDYEELPAILTAQEARQAETYVIPP
LKLARGDAAARLAAAPHRESGEMLLGGQEQFYLEGQIAYAVPKDDDGMHVYCSTQHPSEMQHLVAHVLGVASHNVLVECR
RMGGGFGGKESQSGLFACCAALAAWKLLCPVKLRPDRDDDMLITGKRHDFHYRFDVGYDDDGRLDGVALEMTSRCGFSAD
LSGPVMTRAVCHFDNAYWLGDVDIAGYCGKTNTQSNTAFRGFGGPQGAFAIEYILDDIARALGRDPLDVRYANLYGKTER
NVTPYGQTVEDNVLQELLGELETTSDYRARRAGVRDFNARNTVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGSVL
VNHGGTEMGQGLNTKVAQVVAHELGIRFGRIRVTATDTSKVANTSATAASTGSDLNGKAAQDAARQLRERLAVFAAKQFG
DGKVDAADVKFGNDFVWVGGASVPFGEVIAKAYLARVQLWSDGFYATPKLYWDQSKLQGRPFYYYSYGAAVSEVVIDTLT
GEMRTLRVDALHDVGASLNPALDIGQVEGAFIQGMGWLTTEELWWNAGGKLMTHAPSTYKIPTVNDTPPEFNVRLFQNRN
VEDSIHRSKAVGEPPLLLPFSVFFAVRDAIAAVGDYQVNPPLDAPATGESILRAVNAVRAASAARAG

Specific function: Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism) [H]

COG id: COG4631

COG function: function code F; Xanthine dehydrogenase, molybdopterin-binding subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=768, Percent_Identity=42.96875, Blast_Score=579, Evalue=1e-165,
Organism=Homo sapiens, GI71773480, Length=777, Percent_Identity=37.7091377091377, Blast_Score=476, Evalue=1e-134,
Organism=Escherichia coli, GI1789230, Length=752, Percent_Identity=27.6595744680851, Blast_Score=205, Evalue=7e-54,
Organism=Escherichia coli, GI1789246, Length=768, Percent_Identity=26.0416666666667, Blast_Score=189, Evalue=5e-49,
Organism=Escherichia coli, GI1786478, Length=737, Percent_Identity=24.2876526458616, Blast_Score=93, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17540638, Length=769, Percent_Identity=40.8322496749025, Blast_Score=508, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI32566215, Length=708, Percent_Identity=32.2033898305085, Blast_Score=335, Evalue=6e-92,
Organism=Caenorhabditis elegans, GI17539860, Length=720, Percent_Identity=32.0833333333333, Blast_Score=319, Evalue=4e-87,
Organism=Drosophila melanogaster, GI17737937, Length=763, Percent_Identity=43.6435124508519, Blast_Score=580, Evalue=1e-165,
Organism=Drosophila melanogaster, GI24647199, Length=775, Percent_Identity=30.9677419354839, Blast_Score=322, Evalue=8e-88,
Organism=Drosophila melanogaster, GI24647193, Length=768, Percent_Identity=32.2916666666667, Blast_Score=321, Evalue=1e-87,
Organism=Drosophila melanogaster, GI24647201, Length=762, Percent_Identity=30.7086614173228, Blast_Score=291, Evalue=1e-78,
Organism=Drosophila melanogaster, GI24647195, Length=774, Percent_Identity=30.8785529715762, Blast_Score=289, Evalue=5e-78,
Organism=Drosophila melanogaster, GI24647197, Length=774, Percent_Identity=30.8785529715762, Blast_Score=288, Evalue=8e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 85001; Mature: 85001

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQQAEPFLNTLDQQADAAQVHISRPHESAHLHVSGRATYTDDIPIVAGTLHAALGLSAK
CCCCCCHHHHHHHCCCCCEEEEEECCCCCEEEEEECCEEECCCCCEEHHHHHHHHCCCCC
PHAKIVSMNFDAVRATPGVVAVFTADDIPGVNDCGPIIHDDPVLAKGIVQFVGQPMFIVV
CCCEEEEECCCCEECCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEE
ATSHDIARLAARRAQVDYEELPAILTAQEARQAETYVIPPLKLARGDAAARLAAAPHRES
ECCCHHHHHHHHHHCCCHHHCCHHEEHHHHHCCCEEECCCHHCCCCCHHHHHHCCCCCCC
GEMLLGGQEQFYLEGQIAYAVPKDDDGMHVYCSTQHPSEMQHLVAHVLGVASHNVLVECR
CCEEECCCCEEEEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHH
RMGGGFGGKESQSGLFACCAALAAWKLLCPVKLRPDRDDDMLITGKRHDFHYRFDVGYDD
HHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCEEEECCCCCEEEEEECCCCC
DGRLDGVALEMTSRCGFSADLSGPVMTRAVCHFDNAYWLGDVDIAGYCGKTNTQSNTAFR
CCCCCCEEEEEHHCCCCCCCCCCCHHHHHHHHCCCEEEEECCEEECCCCCCCCCCCCEEE
GFGGPQGAFAIEYILDDIARALGRDPLDVRYANLYGKTERNVTPYGQTVEDNVLQELLGE
CCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
LETTSDYRARRAGVRDFNARNTVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGSVL
HCCCCHHHHHHCCCCCCCCHHHHHHCCCEECEEEEEEEEEEEEECCCCCEEEEEECCEEE
VNHGGTEMGQGLNTKVAQVVAHELGIRFGRIRVTATDTSKVANTSATAASTGSDLNGKAA
EECCCHHHCCCCCHHHHHHHHHHHCCEEEEEEEEECCCHHHCCCCCCCCCCCCCCCCHHH
QDAARQLRERLAVFAAKQFGDGKVDAADVKFGNDFVWVGGASVPFGEVIAKAYLARVQLW
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHEEE
SDGFYATPKLYWDQSKLQGRPFYYYSYGAAVSEVVIDTLTGEMRTLRVDALHDVGASLNP
CCCCEECCEEEECHHHCCCCCEEEEECCHHHHHHHHHHHCCCEEEEEEEHHHHCCCCCCC
ALDIGQVEGAFIQGMGWLTTEELWWNAGGKLMTHAPSTYKIPTVNDTPPEFNVRLFQNRN
CCCCCCCCCHHCCCCCCCEEHHHHHCCCCEEEEECCCCEECCCCCCCCCCCEEEEEECCC
VEDSIHRSKAVGEPPLLLPFSVFFAVRDAIAAVGDYQVNPPLDAPATGESILRAVNAVRA
CHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
ASAARAG
HHHHCCC
>Mature Secondary Structure
MNQQAEPFLNTLDQQADAAQVHISRPHESAHLHVSGRATYTDDIPIVAGTLHAALGLSAK
CCCCCCHHHHHHHCCCCCEEEEEECCCCCEEEEEECCEEECCCCCEEHHHHHHHHCCCCC
PHAKIVSMNFDAVRATPGVVAVFTADDIPGVNDCGPIIHDDPVLAKGIVQFVGQPMFIVV
CCCEEEEECCCCEECCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEE
ATSHDIARLAARRAQVDYEELPAILTAQEARQAETYVIPPLKLARGDAAARLAAAPHRES
ECCCHHHHHHHHHHCCCHHHCCHHEEHHHHHCCCEEECCCHHCCCCCHHHHHHCCCCCCC
GEMLLGGQEQFYLEGQIAYAVPKDDDGMHVYCSTQHPSEMQHLVAHVLGVASHNVLVECR
CCEEECCCCEEEEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHH
RMGGGFGGKESQSGLFACCAALAAWKLLCPVKLRPDRDDDMLITGKRHDFHYRFDVGYDD
HHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCEEEECCCCCEEEEEECCCCC
DGRLDGVALEMTSRCGFSADLSGPVMTRAVCHFDNAYWLGDVDIAGYCGKTNTQSNTAFR
CCCCCCEEEEEHHCCCCCCCCCCCHHHHHHHHCCCEEEEECCEEECCCCCCCCCCCCEEE
GFGGPQGAFAIEYILDDIARALGRDPLDVRYANLYGKTERNVTPYGQTVEDNVLQELLGE
CCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
LETTSDYRARRAGVRDFNARNTVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGSVL
HCCCCHHHHHHCCCCCCCCHHHHHHCCCEECEEEEEEEEEEEEECCCCCEEEEEECCEEE
VNHGGTEMGQGLNTKVAQVVAHELGIRFGRIRVTATDTSKVANTSATAASTGSDLNGKAA
EECCCHHHCCCCCHHHHHHHHHHHCCEEEEEEEEECCCHHHCCCCCCCCCCCCCCCCHHH
QDAARQLRERLAVFAAKQFGDGKVDAADVKFGNDFVWVGGASVPFGEVIAKAYLARVQLW
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHEEE
SDGFYATPKLYWDQSKLQGRPFYYYSYGAAVSEVVIDTLTGEMRTLRVDALHDVGASLNP
CCCCEECCEEEECHHHCCCCCEEEEECCHHHHHHHHHHHCCCEEEEEEEHHHHCCCCCCC
ALDIGQVEGAFIQGMGWLTTEELWWNAGGKLMTHAPSTYKIPTVNDTPPEFNVRLFQNRN
CCCCCCCCCHHCCCCCCCEEHHHHHCCCCEEEEECCCCEECCCCCCCCCCCEEEEEECCC
VEDSIHRSKAVGEPPLLLPFSVFFAVRDAIAAVGDYQVNPPLDAPATGESILRAVNAVRA
CHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
ASAARAG
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]