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The map label for this gene is hmp [H]

Identifier: 115350681

GI number: 115350681

Start: 703358

End: 704566

Strand: Direct

Name: hmp [H]

Synonym: Bamb_0627

Alternate gene names: 115350681

Gene position: 703358-704566 (Clockwise)

Preceding gene: 115350680

Following gene: 115350689

Centisome position: 19.78

GC content: 66.91

Gene sequence:

>1209_bases
ATGACCCACATCACCGCTGACCAGATGGCCCGTGTGAAGGCCACCGCCCCTGTCCTTGCCGAGCACGGCGCGACGATCAC
GAAGCACTTCTATCAGCGCATGTTCGCGCGTCATCCGGAACTGAAGAACCTGTTCAACCAGACGCACCAGAAGACCGGCA
GCCAGCCGGAAACGCTCGCGAAGGCGGTCTACGCGTATGCCGCGAACATCGACAATCTCGGTGCGCTGGGCGGCGCGGTG
TCGCGCATCTCGCACAAGCACGCGAGCCTCAATATCCGTCCGGAGCATTACCCGATCGTCGGCGAGAACCTGCTCGCGTC
GATCGTCGAAGTGCTCGGCGACGCGGTCGACGCGGAAACGCTCGAAGCCTGGCGCGTCGCGTACGGCCAGCTCGCGCAGA
TCATGATCGGCGCCGAGGCCGACCTGTACGCGAACGCCGCATGGAGCGGCTTCCGCCCGTTCAAGGTCGCCCGCAAGGTG
CGCGAAAGCGACGAGATCACGTCGTTCTACCTGACCCCCGCCGACGGCGGCGACGCGCCGAAGTTCGAGCCGGGCCAGTA
CATCTCGGTGAAGCGCTTCGTCGGCGAGCTGGGTGTCGACCAGCCGCGCCAGTACAGCCTGTCCGATGCGCCGCACGGCA
AGTGGCTGCGCATTTCGGTGAAGCGCGAGGCGGGCAGGGCGGAAGCGATCCCGGCCGGCAAGGTGTCGACGCTGATGCAC
GATGGCGTGGAAGAGGGCGCGATCGTCGAAGTGACCGCGCCGATGGGCGACTTCTCGCTGAAGCGCGATGTCGAGACGCC
GGTCGTGCTGATCTCGGGCGGTGTCGGCATCACGCCGATGATGTCGATGGCGTCGACGCTGATCGCCGAAGGCAGCAAGC
GCGAAGTGCAGTTCGTCCACGCGTGCCGTTCGGGCGCGGTGCACGCGTTCCGCGACTGGCTGAACGACGCGGCGCGCGAG
CACGCGAACGTGAAGCGCACGGTGCTGTACGAGCTGGTCGGCCCGAACGACCGTGCCGGTGTCGATCACGACCTCGAAGG
GCGCCTGACGCCGGAGCGCGTGAAGCAGCATGCGCTGGTGCCGGATGCCGACTACTACATCTGCGGCCCGATCGCGTTCA
TGAAGGCGCAACGCGATGCGCTCGTCGCGCTGGGCGTCGCGCCGGAGCGTGTGAACACCGAGATCTTCGGCTCGGGTGCG
CTCGAGTGA

Upstream 100 bases:

>100_bases
CGCTGACGCGCGGCATCGATTTCCGCACTGCGACAATTTGTCCGAGGGGCGCTTTAATTTTAAAGATGTATCGTATGTGC
ATGTTTAACGGAGAACGCAC

Downstream 100 bases:

>100_bases
TGCGCGAACGGACGGTCTCAGGCCAGTAAAAAAGCCCGGCGCGAGCCGGGCTTCGATTTTGTCGCGTGCATGACGATGTC
AGGCACGCAGCATCAGCGTG

Product: globin

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MTHITADQMARVKATAPVLAEHGATITKHFYQRMFARHPELKNLFNQTHQKTGSQPETLAKAVYAYAANIDNLGALGGAV
SRISHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDAETLEAWRVAYGQLAQIMIGAEADLYANAAWSGFRPFKVARKV
RESDEITSFYLTPADGGDAPKFEPGQYISVKRFVGELGVDQPRQYSLSDAPHGKWLRISVKREAGRAEAIPAGKVSTLMH
DGVEEGAIVEVTAPMGDFSLKRDVETPVVLISGGVGITPMMSMASTLIAEGSKREVQFVHACRSGAVHAFRDWLNDAARE
HANVKRTVLYELVGPNDRAGVDHDLEGRLTPERVKQHALVPDADYYICGPIAFMKAQRDALVALGVAPERVNTEIFGSGA
LE

Sequences:

>Translated_402_residues
MTHITADQMARVKATAPVLAEHGATITKHFYQRMFARHPELKNLFNQTHQKTGSQPETLAKAVYAYAANIDNLGALGGAV
SRISHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDAETLEAWRVAYGQLAQIMIGAEADLYANAAWSGFRPFKVARKV
RESDEITSFYLTPADGGDAPKFEPGQYISVKRFVGELGVDQPRQYSLSDAPHGKWLRISVKREAGRAEAIPAGKVSTLMH
DGVEEGAIVEVTAPMGDFSLKRDVETPVVLISGGVGITPMMSMASTLIAEGSKREVQFVHACRSGAVHAFRDWLNDAARE
HANVKRTVLYELVGPNDRAGVDHDLEGRLTPERVKQHALVPDADYYICGPIAFMKAQRDALVALGVAPERVNTEIFGSGA
LE
>Mature_401_residues
THITADQMARVKATAPVLAEHGATITKHFYQRMFARHPELKNLFNQTHQKTGSQPETLAKAVYAYAANIDNLGALGGAVS
RISHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDAETLEAWRVAYGQLAQIMIGAEADLYANAAWSGFRPFKVARKVR
ESDEITSFYLTPADGGDAPKFEPGQYISVKRFVGELGVDQPRQYSLSDAPHGKWLRISVKREAGRAEAIPAGKVSTLMHD
GVEEGAIVEVTAPMGDFSLKRDVETPVVLISGGVGITPMMSMASTLIAEGSKREVQFVHACRSGAVHAFRDWLNDAAREH
ANVKRTVLYELVGPNDRAGVDHDLEGRLTPERVKQHALVPDADYYICGPIAFMKAQRDALVALGVAPERVNTEIFGSGAL
E

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=399, Percent_Identity=41.1027568922306, Blast_Score=290, Evalue=8e-80,
Organism=Escherichia coli, GI1787658, Length=261, Percent_Identity=25.6704980842912, Blast_Score=73, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321673, Length=396, Percent_Identity=37.3737373737374, Blast_Score=245, Evalue=8e-66,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 43757; Mature: 43626

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHITADQMARVKATAPVLAEHGATITKHFYQRMFARHPELKNLFNQTHQKTGSQPETLA
CCCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHH
KAVYAYAANIDNLGALGGAVSRISHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDAET
HHHHHHHCCCCCHHHHHHHHHHHHHHHCEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHH
LEAWRVAYGQLAQIMIGAEADLYANAAWSGFRPFKVARKVRESDEITSFYLTPADGGDAP
HHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCC
KFEPGQYISVKRFVGELGVDQPRQYSLSDAPHGKWLRISVKREAGRAEAIPAGKVSTLMH
CCCCCCEEHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHH
DGVEEGAIVEVTAPMGDFSLKRDVETPVVLISGGVGITPMMSMASTLIAEGSKREVQFVH
CCCCCCCEEEEECCCCCCCHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHH
ACRSGAVHAFRDWLNDAAREHANVKRTVLYELVGPNDRAGVDHDLEGRLTPERVKQHALV
HHHCCCHHHHHHHHHHHHHHHCCCHHEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCC
PDADYYICGPIAFMKAQRDALVALGVAPERVNTEIFGSGALE
CCCCEEEECHHHHHHHCCCEEEEECCCCHHCCCEECCCCCCC
>Mature Secondary Structure 
THITADQMARVKATAPVLAEHGATITKHFYQRMFARHPELKNLFNQTHQKTGSQPETLA
CCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHH
KAVYAYAANIDNLGALGGAVSRISHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDAET
HHHHHHHCCCCCHHHHHHHHHHHHHHHCEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHH
LEAWRVAYGQLAQIMIGAEADLYANAAWSGFRPFKVARKVRESDEITSFYLTPADGGDAP
HHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCC
KFEPGQYISVKRFVGELGVDQPRQYSLSDAPHGKWLRISVKREAGRAEAIPAGKVSTLMH
CCCCCCEEHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHH
DGVEEGAIVEVTAPMGDFSLKRDVETPVVLISGGVGITPMMSMASTLIAEGSKREVQFVH
CCCCCCCEEEEECCCCCCCHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHH
ACRSGAVHAFRDWLNDAAREHANVKRTVLYELVGPNDRAGVDHDLEGRLTPERVKQHALV
HHHCCCHHHHHHHHHHHHHHHCCCHHEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCC
PDADYYICGPIAFMKAQRDALVALGVAPERVNTEIFGSGALE
CCCCEEEECHHHHHHHCCCEEEEECCCCHHCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]